OLEMAR AM 40 Tablet 10's
OLEMAR AM 40 Tablet 10's

OLEMAR AM 40 Tablet 10's

10 Tablet(s) in a Strip Mkt: Shrrishti Health Care Products Pvt Ltd Country of Origin: India
Hypertension Rx required
MRP ₹120.00
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OLEMAR AM 40 Tablet 10's ₹98.40
MRP ₹120.00
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Generic Name
Amlodipine 5 mg+Olmesartan 40 mg
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Introduction About OLEMAR AM 40 TABLET

OLEMAR AM 40 TABLET is used for the management of high blood pressure among patients who remain unresponsive to therapy with either olmesartan or amlodipine alone. It is a combination of Amlodipine and Olmesartan, which belongs to the group of medicines called Antihypertensive agents.

During management with OLEMAR AM 40 TABLET, your doctor might check your kidney function, blood pressure, and electrolyte (Ex. potassium) concentration in your blood at regular intervals to avoid the risk of unwanted side effects. Avoid consumption of grapefruit or grapefruit juice while taking the medicine, as it could lead to an unpredictable decrease in blood pressure. Before taking OLEMAR AM 40 TABLET, inform your doctor if you have any liver, kidney, or heart disease. It is not recommended in early pregnancy and must not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if used at that stage.

It is not recommended for mothers who are breast-feeding, and your doctor may choose another treatment for you if you wish to breast-feed, especially if your baby is newborn, or was born prematurely. OLEMAR AM 40 TABLET is not recommended for use in children and adolescents (aged under 18 years) due to a lack of safety data. It should be taken with caution in elderly patients (aged 65 years or older). The most common side effects are headache, dizziness, tiredness, edema, sore throat, and constipation. Consult your doctor if any of the side effects worsen.

Uses Of OLEMAR AM 40 TABLET

How OLEMAR AM 40 TABLET Works

OLEMAR AM 40 TABLET effectively reduces elevated blood pressure, where Olmesartan acts by inhibiting the actions of angiotensin-II (a peptide hormone that causes narrowing of blood vessels and an increase in blood pressure) at the angiotensin-II receptors of the kidneys, and Amlodipine acts by blocking the influx of calcium in the blood vessels by inhibiting the voltage-gated calcium channels, thus causing vascular smooth muscle relaxation, vasodilation, and a marked decrease in blood pressure.

How to use OLEMAR AM 40 TABLET

  • Take OLEMAR AM 40 TABLET as advised by your physician
  • Swallow the medicine with a glass of water. Do not crush or chew the medicine
  • Your doctor will decide the correct dose and duration of OLEMAR AM 40 TABLET for you depending upon your age, body weight, and disease condition

Side Effects Of OLEMAR AM 40 TABLET

Common Side Effects of OLEMAR AM 40 TABLET:

  • dizziness
  • headache
  • tiredness
  • sore throat, runny nose, cough
  • diarrhea, constipation, abdominal pain, or indigestion

Stop taking OLEMAR AM 40 TABLET and contact your doctor immediately if you experience any of the following side effects:

  • severe allergic reactions (such as skin rash with itching and swelling of the face, mouth, and/or larynx)
  • signs of hypotension (such as severe dizziness or light-headedness and fainting)
  • severe, persistent diarrhea with substantial weight loss
  • yellowing of the whites of the eyes, dark urine, and itching of the skin

Warning & Precautions

Pregnancy

Contraindicated

It is not recommended in early pregnancy and must not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if used at that stage.

Breastfeeding

Contraindicated

It is not recommended for mothers who are breast-feeding, and your doctor may choose another treatment for you if you wish to breast-feed, especially if your baby is newborn, or was born prematurely.

Driving and Using Machines

Use with Caution

Do not drive or operate any tools or machines if you experience dizziness, sleepiness, or headache after taking the medicine.

Alcohol

Consult your doctor

Avoid consuming alcohol while taking this medicine, as it could aggravate your dizziness and tiredness.  

Kidney

Consult your doctor

OLEMAR AM 40 TABLET is not recommended for use in patients with impaired kidney function and should be used with caution in patients with kidney problems or with a surgical history of kidney transplant.

Liver

Consult your doctor

OLEMAR AM 40 TABLET is not recommended for use in patients with severe liver problems (such as biliary obstruction, gallstones, and jaundice) and should be used with caution in patients with liver disease.  

Allergy

Contraindicated

Do not take OLEMAR AM 40 TABLET if you are allergic to Olmesartan, Amlodipine, or any other ingredients of this medicine.

Heart Disease

Contraindicated

OLEMAR AM 40 TABLET is not recommended for use in patients with heart disease (such as aortic stenosis (narrowing of the aorta), cardiogenic shock, circulatory failure, or heart attack).

Use In Pediatrics

Contraindicated

OLEMAR AM 40 TABLET is not recommended for use in children and adolescents (aged below 18 years) due to a lack of safety data.  

Use In Geriatrics

Use with Caution

OLEMAR AM 40 TABLET should be taken with caution in elderly patients (aged 65 years or older). Proper dose adjustments and careful monitoring of blood pressure and kidney function are required in such patients.  

Others

OLEMAR AM 40 TABLET is not recommended for use if you have:

  • diabetes-related kidney problems
  • severe hypotension (very low blood pressure)

Before taking this medicine, inform your physician if you:

  • have severe vomiting and/or diarrhea
  • are on a low-sodium diet
  • have hyperkalemia (increased levels of potassium in the blood)
  • have problems with the adrenal glands

Interactions

A. Drug-Drug interactions:

Before taking the medicine, inform your doctor if you are taking any of these medicines:

  • Angiotensin-converting enzyme (ACE) inhibitors (Ex. enalapril, lisinopril, ramipril) or aliskiren
  • Potassium-containing medicines (Ex. potassium supplements, salt substitutes containing potassium (Ex. losartan potassium)
  • Diuretics (Ex. spironolactone)
  • Non-steroidal anti-inflammatory drugs (Ex. ibuprofen, aspirin, diclofenac)
  • Antacids (Ex. aluminium hydroxide or magnesium hydroxide)
  • Bile acid sequestrants (Ex. colesevelam, simvastatin)
  • Anti-viral agents (Ex. ritonavir, nelfinavir, or indinavir)
  • Antifungal agents (Ex. ketoconazole or itraconazole)
  • Immunosuppressants (Ex. tacrolimus, sirolimus, temsirolimus, everolimus, and cyclosporin)
  • Anticoagulants (Ex. heparin)
  • Anti-manic agents (Ex. Lithium)
  • Calcium-channel blockers (Ex. Diltiazem, Verapamil)
  • Antibiotics (Ex. Rifampicin, Erythromycin or Clarithromycin)
  • St. John’s wort
  • Skeletal muscle relaxants (Ex. Dantrolene)

B. Drug-Food interaction:

Avoid eating grapefruit or consuming grapefruit juice while taking OLEMAR AM 40 TABLET, as it could lead to an increase in the levels of amlodipine in the blood, which may lead to an unpredictable decrease in blood pressure.

Overdosage:

If you or anyone else accidentally takes too much of OLEMAR AM 40 TABLET, contact your doctor immediately or go to a hospital right away. Overdosage symptoms include low blood pressure, dizziness, and a fast or slow heartbeat.

Synopsis

Drug :   Amlodipine, Olmesartan
Pharmacological Category :   Antihypertensive agents
Therapeutic Indication :   Hypertension
Dosage Forms :   Tablet

More Information

FAQs About OLEMAR AM 40 TABLET

Q: What is OLEMAR AM 40 TABLET used for?

A: OLEMAR AM 40 TABLET is a combination of Amlodipine and olmesartan, which belongs to the group of medicines called Antihypertensive agents. It is indicated for the management of high blood pressure among patients who remain unresponsive to therapy with either olmesartan or amlodipine alone.

Q: What are the side effects of taking OLEMAR AM 40 TABLET?

A: The most common side effects are headache, dizziness, tiredness, edema, sore throat, and constipation. 

Q: How does OLEMAR AM 40 TABLET work?

A: OLEMAR AM 40 TABLET effectively reduces elevated blood pressure, where olmesartan acts by inhibiting the actions of angiotensin-II (a peptide hormone that causes narrowing of blood vessels and an increase in blood pressure) at the angiotensin-II receptors of the kidneys, and Amlodipine acts by blocking the influx of calcium in the blood vessels by inhibiting the voltage-gated calcium channels, thus causing vascular smooth muscle relaxation, vasodilation, and a marked decrease in blood pressure.

Q: What are the precautions that I should follow while taking OLEMAR AM 40 TABLET?

A: Before taking OLEMAR AM 40 TABLET, inform your doctor if you have diabetes, liver, kidney, or heart disease, or if you are pregnant or might be pregnant, as a precaution. Avoid consumption of grapefruit or grapefruit juice while taking the medicine, as it could lead to an unpredictable decrease in blood pressure.

Q: Can I consume alcohol while taking OLEMAR AM 40 TABLET?

A: Avoid consumption of alcohol while taking this medicine, as it could aggravate your dizziness and tiredness. 

Q: Can OLEMAR AM 40 TABLET be taken during pregnancy?

A: No, OLEMAR AM 40 TABLET is not recommended for use in early pregnancy and should not be taken when more than 3 months pregnant, as it may cause serious harm to your baby. 

Q: Does OLEMAR AM 40 TABLET cause weight gain?

A: OLEMAR AM 40 TABLET does not have any direct impact on your body weight. However, it can cause fluid retention (edema) in your hands, arms, legs, and feet, which might make you feel heavy. 

Q: How long should I take OLEMAR AM 40 TABLET?

A: Continue to take OLEMAR AM 40 TABLET as long as your doctor tells you to do so. Do not stop taking OLEMAR AM 40 TABLET on your own once your blood pressure is controlled without consulting your doctor, as it could raise your blood pressure again. 

Q: Can OLEMAR AM 40 TABLET make me feel dizzy?

A: Yes, OLEMAR AM 40 TABLET can make you feel dizzy. Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve during or after management with OLEMAR AM 40 TABLET.

Q: Is OLEMAR AM 40 TABLET safe to use in patients with liver disease?

A: OLEMAR AM 40 TABLET is not recommended for use in patients with severe liver problems (such as biliary obstruction, gall stones, or jaundice) and should be taken with caution in patients with liver disease.

References

1. KD. Tripathi. Antihypertensive Drugs and Drugs Affecting Renin Angiotensin System and Plasma Kinins. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 562-563 & 505-508.

2. Randa Hilal-Dandan. Renin and angiotensin. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 738-739.

3. Thomas Michel and Brian B. Hoffman. Treatment of myocardial ischemia and hypertension. Goodman & Gilman’s: The Pharmacological Basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 755-760.

4. Gerald G. Briggs and Roger K. Freeman. A & O. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 196-198 & 2852-2853.

5. Daiichi Sankyo, Inc.: Parallel-Group Comparison of Olmesartan (OLM), Amlodipine (AML), and Hydrochlorothiazide (HCTZ) in Hypertension. NIH U.S. National Library of Medicine, ClinicalTrials.gov. [Revised in January 2019] [Accessed on 1st July 2024]  click here

6. Henry Punzi, Joel M Neutel, Dean J Kereiakes, Ali Shojaee, William F Waverczak, Robert Dubiel, and Jen-Fue Maa. Efficacy of amlodipine and olmesartan medoxomil in patients with hypertension: the AZOR Trial Evaluating Blood Pressure Reductions and Control (AZTEC) study. NIH, National Library of Medicine, National Center for Biotechnology Information. PuMed.gov. August 2010. [Accessed on 1st July 2024]  click here

7. Henry Punzi, Ali Shojaee, William F Waverczak, Jen-Fue Maa. Efficacy of amlodipine and olmesartan medoxomil in hypertensive patients with diabetes and obesity. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed.gov. June 2011. [Accessed on 1st July 2024]  href = "https://pubmed.ncbi.nlm.nih.gov/21649842/"target="_blank"> click here

8. Daiichi Sankyo Europe GmbH. Electronic Medicines Compendium (EMC). [Revised in September 2021] [Accessed on 1st July 2024]  click here

9. Torrent Pharmaceuticals Ltd., Olmetor AM. Torrentian.com. [Revised in October 2019]. [Accessed on 1st July 2024]  click here

10. Cipla Ltd. Olmecip AM Tablets (Olmesartan medoxomil + Amlodipine). Ciplamed.com. [Revised in February 2020]. [Accessed on 1st July 2024]  click here

11. John Lee Pharmaceuticals Pvt. Ltd. Omten-40 AM. [Accessed on 1st July 2024]  click here

Author Details

Written By Srilekha. R - B.Pharm
Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile
Last updated on 19 Nov 2024 | 04:09 PM(IST)
    Net Qty
    1 N
    Shelf Life
    720 Days
    Item Weight
    17.5 g
    Ingredient
    Amlodipine 5 mg+Olmesartan 40 mg
    Hsn Code
    30049079
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