Introduction About OCUVIR SR 1.2GM TABLET

OCUVIR SR 1.2GM TABLET contains Acyclovir, which belongs to the group of medicines called Antivirals. It is used to manage chickenpox, shingles, cold sores, genital herpes and other herpes simplex infections to manage infections in people with a weakened immune system.

Cold sores, (a virus causing contagious sores, most often around the mouth or on the genitals), genital herpes (a common sexually transmitted infection caused by the herpes simplex virus and symptoms include genital pain and sores, pain, itching and small sores).

Before taking OCUVIR SR 1.2GM TABLET inform your doctor if you have kidney problems. OCUVIR SR 1.2GM TABLET should be used with caution among pregnant or breastfeeding women. Consult your doctor before taking OCUVIR SR 1.2GM TABLET.

The most common side effects of taking OCUVIR SR 1.2GM TABLET are headache, dizziness, feeling or being sick, diarrhea, stomach pain and rashes. Contact your doctor if the symptom persists.

Uses Of OCUVIR SR 1.2GM TABLET

OCUVIR SR 1.2GM TABLET is used in the following conditions:

• Manage chickenpox and Herpes zoster (shingles)
• Manage cold sores, genital herpes
• Manage herpes simplex infections
• Prevents problems in those people infected with a virus
• Prevents infections in low immunity patients

How OCUVIR SR 1.2GM TABLET Works

OCUVIR SR 1.2GM TABLET works by killing or stopping the growth of viruses (herpes virus). It has a higher affinity for viral DNA cells than human DNA cells and incorporates into the viral DNA and causes DNA chain termination and inactivation, leading to the death of cells.

How to use OCUVIR SR 1.2GM TABLET

Take OCUVIR SR 1.2GM TABLET as advised by your physician. Swallow the medicine by mouth with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

Side Effects Of OCUVIR SR 1.2GM TABLET

How To Manage Side Effects

Headache:

Take rest and drink plenty of fluids. If not subsided. Consult your doctor if your symptom gets worse or persist.

Diarrhea:

Drink lots of fluids, such as water or fruit juice to keep you hydrated. Do not consume any medicine on your own without consulting your doctor.

Stomach pain:

Try to rest and relax. Eat smaller meals but take them frequently. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.

Dizziness:

If OCUVIR SR 1.2GM TABLET makes you feel dizzy, take rest until you feel better. Do not drive or operate machines.

Nausea or vomiting:

Take simple meals and do not eat rich or spicy food.

Sensitivity to sunlight:

Stay out of the bright sun and use sun creams (SPF-15) when going outside. If the symptom does not improve, contact your doctor.

Itchy skin:

Try to use an unscented moisturiser. If the symptom does not improve, contact your doctor.

Warning & Precautions

Pregnancy

OCUVIR SR 1.2GM TABLET should be used with caution in pregnant women. Consult your doctor before taking it.

Breastfeeding

OCUVIR SR 1.2GM TABLET should be used with caution in breastfeeding women. Consult your doctor before taking it.

Driving and Using Machines

Do not drive or operate any machines if you feel dizzy, drowsiness or asleep after taking OCUVIR SR 1.2GM TABLET.

Kidney

OCUVIR SR 1.2GM TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking OCUVIR SR 1.2GM TABLET.

Allergy

Do not take OCUVIR SR 1.2GM TABLET if you are allergic to Acyclovir, valacyclovir or any of the other ingredients of this medicine.

Interactions

A. Drug - Drug interactions:

Before taking OCUVIR SR 1.2GM TABLET, inform your doctor if you are taking any of the following medicine:

• probenecid (used to manage gout)
• cimetidine (used to manage stomach ulcers)
• drugs acting on the immune system (Ex. mycophenolate mofetil)
• amikacin, amphotericin B, atovaquone, lumefantrine, mefloquine, azithromycin, capreomycin, caspofungin, clarithromycin, clindamycin, doxycycline, erythromycin (used to manage infections)
• antivirals Ex. valacyclovir, valganciclovir, ganciclovir, tenofovir, cidofovir (used to manage viral infections)
• albendazole (used to manage parasitic infections)
• dapsone, isoniazid (used to manage mycobacterial infections)
• antifungals Ex. fluconazole, itraconazole

B. Drug - Food interaction:

NA

Overdosage:

If you or anyone else accidentally take too much of OCUVIR SR 1.2GM TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are agitation, coma, seizures, lethargy etc.

Synopsis

More Information

• Keep OCUVIR SR 1.2GM TABLET out of the sight and reach from children
• Store OCUVIR SR 1.2GM TABLET below 25°C

FAQs About OCUVIR SR 1.2GM TABLET

Can OCUVIR SR 1.2GM TABLET be used to manage Urinary Tract Infections?

Yes. OCUVIR SR 1.2GM TABLET may be used to manage cystitis caused by the herpes simplex virus. Consult your doctor before taking OCUVIR SR 1.2GM TABLET.

What precautions do I need to follow while taking OCUVIR SR 1.2GM TABLET?

Patients taking OCUVIR SR 1.2GM TABLET must inform their doctor about their pre-existing disease conditions like kidney, heart or liver problems and if they are elderly above 65 years.

Can OCUVIR SR 1.2GM TABLET be used on pregnancy?

Yes. OCUVIR SR 1.2GM TABLET should be used with caution in pregnant women. Consult your doctor before taking OCUVIR SR 1.2GM TABLET.

Who should avoid taking OCUVIR SR 1.2GM TABLET?

OCUVIR SR 1.2GM TABLET is not recommended for patients having kidney diseases or elderly above 65 years and patients with allergic history to acyclovir. Consult your doctor before taking OCUVIR SR 1.2GM TABLET.

How long does it take for OCUVIR SR 1.2GM TABLET to show its effects?

OCUVIR SR 1.2GM TABLET works within 24-48 hours of administration.

Can OCUVIR SR 1.2GM TABLET manage a bacterial infection?

No. OCUVIR SR 1.2GM TABLET is an antiviral drug used to manage herpes simplex virus, chicken pox and shingles. Talk to your doctor before taking OCUVIR SR 1.2GM TABLET.

References

1. KD Tripathi. Antiviral drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page - 799

2. Laurence L. Brunton, Randa Hilal-Dandan, Bjorn C. Knollman, Antiviral agents (Non-retroviral), Goodman & Gillman’s: The pharmacological basics of therapeutics, 13th edition. 2018. Page – 1105

3. Terapia S.A & Sun Pharmaceutical Industries Europe BV. Electronic Medicines Compendium (EMC). [Revised in October 2019] [Accessed on 18th April 2022] https://www.medicines.org.uk/emc/files/pil.4336.pdf

4. Terapia S.A. & Sun Pharmaceutical Industries Europe BV. Electronic Medicines Compendium (EMC). [Revised in October 2019] [Accessed on 18th April 2022] https://www.medicines.org.uk/emc/files/pil.4335.pdf

5. GlaxoSmithKline. U.S. Food & Drug Administration. [Revised in June 2005] [Accessed on 18th April 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/018828s030,020089s019,019909s020lbl.pdf

6. Acyclovir. CDSCO. [Revised in September 2010] [Accessed on 18th April 2022] https://cdscoonline.gov.in/CDSCO/Drugs

7. Significant drug interactions for drugs used to treat or prevent opportunistic infections https://clinicalinfo.hiv.gov/en/guidelines/pediatric-opportunistic-infection/table-5-significant-drug-interactions-drugs-used-treat

8. Drugbank. Mechanism of action of acyclovir https://go.drugbank.com/drugs/DB00787

Useful Diagnostic Tests

• Herpes Simplex Virus 1 DNA PCR
• Herpes Simplex Virus 1 IgG
• Herpes Simplex Virus 2 DNA PCR
• Herpes Simplex Virus 2 IgG
• Herpes Simplex Virus 2 IgM
• Varicella Zoster IgG
• Varicella Zoster IgM