NOCTORYL Syrup 100ml
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Introduction About NOCTORYL SYRUP
NOCTORYL SYRUP contains Melatonin which belongs to the group of medicines called Hormones. It is used for the management of jetlag (temporary sleep problem that can affect those who travel quickly across multiple time zones) in adults and sleep onset insomnia in children and adolescents aged 6-17 years suffering from attention-deficit hyperactivity disorder (ADHD) where other sleep routine measures have not been sufficient.
Avoid smoking as it may reduce the effect of this medicine and alcohol consumption while taking NOCTORYL SYRUP as it can impair sleep and potentially worsen certain symptoms of jetlag (Ex. headache, morning fatigue and concentration).
NOCTORYL SYRUP should be used with caution in patients with impaired liver or kidney function, epilepsy, autoimmune disease (where the body is attacked by its own immune system), diabetes or impaired glucose tolerance and hereditary fructose intolerance. Consult your doctor before taking it.
NOCTORYL SYRUP is not recommended for use in children under 6 years of age as its safety and effectiveness are not known. It should be used with caution in elderly patients (aged 65 years and above).
The most common side effects of taking NOCTORYL SYRUP are headache and sleepiness. Consult your doctor if any of the side effect worsens or persist for a long period of time.
Uses Of NOCTORYL SYRUP
Manage:
- jetlag in adults
- sleep onset insomnia in children and adolescents aged 6-17 years suffering from attention-deficit hyperactivity disorder (ADHD)
How NOCTORYL SYRUP Works
NOCTORYL SYRUP helps to restore the normal day-and-night rhythm by synchronizing the body’s biological day-and-night rhythm as disturbances in biological rhythm may cause sleep disturbances, daytime tiredness, fatigue, mild mental impairment, irritability and other symptoms. Thus NOCTORYL SYRUP helps to restore the normal day-and-night rhythm and reduce the symptoms.
How to use NOCTORYL SYRUP
Take NOCTORYL SYRUP as advised by your physician. Shake well before use. Use a measuring cup or a spoon to properly measure the dose. Your doctor will decide the correct dose and duration of the management for you depending upon your age, body weight and disease severity.
Side Effects Of NOCTORYL SYRUP
Common
- headache
- sleepiness
Uncommon
- irritability, nervousness, restlessness, anxiety
- abnormal dreams, night sweats, lack of energy and enthusiasm
- dizziness, migraine
- high blood pressure
- abdominal pain, dry mouth, ulceration in mouth, nausea
- skin disorders (such as dermatitis, pruritus, rash, dry skin)
- pain in arms and legs
- menopausal symptoms
- chest pain
- weight gain
Rare
- shingles (herpes zoster)
- altered mood, aggression, agitation, crying, stress symptoms, disorientation, increased sex drive
- fainting, memory impairment, disturbance in attention, uncomfortable sensation in legs (restless legs syndrome), poor quality sleep, tiredness
- visual disturbances, blurred vision, increase tearing
- dizziness or vertigo (spinning), dizziness when standing or sitting
- fast heartbeat
- acid reflux
- blisters in the mouth, tongue ulcers
- stomach upset, vomiting, abnormal bowel sounds
- increased salivation, bad breath
- wind, abdominal discomfort
- abnormal sensations of skin (paraesthesia), skin disorders (eczema, erythema, psoriasis)
- nail disorder
- sudden feeling of heat (hot flush)
- pain, arthritis, muscle spasms, neck pain, night cramps
- passing large volumes of urine, need to urinate at night
- prolonged erection (priapism), swelling of the prostate (prostatitis)
- thirst
Stop taking NOCTORYL SYRUP and contact your doctor immediately if you experience any of the following side effects:
- allergic reactions (signs include swelling of deeper layers of skin (angioedema), itching, swelling of the mouth and tongue (oedema) causing difficulty to breath)
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any machines if you feel drowsiness. Avoid alcohol consumption as it aggravates drowsiness. Consult your doctor if the symptom does not improve.
Dry Mouth
Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.
Headache
Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.
Nausea And Vomiting
Stick to simple meals while taking NOCTORYL SYRUP. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve.
Stomach Pain
Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, inform your doctor.
Warning & Precautions
Pregnancy
ContraindicatedNOCTORYL SYRUP is not recommended for use in pregnant women and women of childbearing potential must use effective contraception. Consult your doctor before taking NOCTORYL SYRUP.
Breastfeeding
ContraindicatedNOCTORYL SYRUP is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking NOCTORYL SYRUP.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel drowsiness and decreased alertness for several hours after taking NOCTORYL SYRUP.
Alcohol
Consult your doctorAvoid alcohol consumption while taking NOCTORYL SYRUP as it can impair sleep and potentially worsen certain symptoms of jetlag (Ex. headache, morning fatigue and concentration).
Kidney
Use with CautionNOCTORYL SYRUP should be used with caution in patients with impaired kidney function. Consult your doctor before taking NOCTORYL SYRUP.
Liver
Use with CautionNOCTORYL SYRUP should be used with caution in patients with impaired liver function. Consult your doctor before taking NOCTORYL SYRUP.
Allergy
ContraindicatedDo not take NOCTORYL SYRUP if you are allergic to melatonin or other ingredients of this medicine.
Use In Pediatrics
Monitoring requiredNOCTORYL SYRUP is not recommended for use in children under 6 years of age as its safety and effectiveness are not known. Contact your child’s doctor for advice.
Use In Geriatrics
Use with CautionNOCTORYL SYRUP should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking NOCTORYL SYRUP.
Others
Before taking NOCTORYL SYRUP, inform your doctor if you have:
- epilepsy
- autoimmune disease (where the body is attacked by its own immune system)
- diabetes or glucose intolerance
- smoking habit
- hereditary fructose intolerance
Interactions
A. Drug-Drug Interactions:
Before taking NOCTORYL SYRUP inform your doctor if you are taking any of following medicines:
- fluvoxamine (used to manage of depression and obsessive-compulsive disorder)
- psoralens (used for managing skin disorders like psoriasis)
- cimetidine (used to manage stomach problems such as ulcers)
- estrogens (used as contraceptives or hormone replacement preparations)
- quinolones, rifampicin (used to manage bacterial infections)
- carbamazepine (used to manage epilepsy)
- benzodiazepines and non-benzodiazepine hypnotics (medicines that induce sleep, Ex. midazolam, temazepam, zaleplon, zolpidem and zopiclone)
- warfarin (used to manage or manage blood clots)
B. Drug-Food Interactions:
Food should not be consumed 2 hours before or 2 hours after taking NOCTORYL SYRUP.
Overdosage:
If you or anyone else accidentally take too much of NOCTORYL SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage includes drowsiness, headache, dizziness and nausea.
Synopsis
| Drug | : | Melatonin |
| Pharmacological Category | : | Hormones |
| Therapeutic Indication | : | Jet-lag, sleep onset insomnia |
| Dosage Forms | : | Tablet, Syrup, Oral Spray, Gel, Lozenges |
More Information
- Keep NOCTORYL SYRUP out of reach of children
- Do not store NOCTORYL SYRUP above 25°C
FAQs About NOCTORYL SYRUP
Q: What is NOCTORYL SYRUP used for?
A: It is used for the management of jetlag (temporary sleep problem that can affect those who travel quickly across multiple time zones) in adults and sleep onset insomnia in children and adolescents aged 6-17 years suffering from attention-deficit hyperactivity disorder (ADHD) where other sleep routine measures have not been sufficient.
Q: Is NOCTORYL SYRUP safe in pregnant women?
A: NOCTORYL SYRUP is not recommended for use in pregnant women and women of childbearing potential must use effective contraception. Consult your doctor for advice before taking it.
Q: Can I drink alcohol while taking NOCTORYL SYRUP?
A: Avoid alcohol consumption while taking NOCTORYL SYRUP as it can impair sleep and potentially worsen certain symptoms of jetlag (Ex. headache, morning fatigue and concentration).
Q: How does NOCTORYL SYRUP work?
A: NOCTORYL SYRUP helps to restore the normal day-and-night rhythm by synchronizing the body’s biological day-and-night rhythm as disturbances in biological rhythm may cause sleep disturbances, daytime tiredness, fatigue, mild mental impairment, irritability and other symptoms. Thus NOCTORYL SYRUP helps to restore the normal day-and-night rhythm and reduce the symptoms.
Q: What are the side effects of taking NOCTORYL SYRUP?
A: The most common side effects of taking NOCTORYL SYRUP are headache and sleepiness. Consult your doctor if any of the side effect worsens or persist for a long period of time.
References
1. K.D. Tripathi. Drugs acting on Central Nervous System. Essentials of Medical Pharmacology. 7th edition. 2013. Page 409
2. Rosemary A. Savage, Nowera Zafar, Sandesh Yohannan, John-Mark M. Miller. Melatonin. National Institute of Health. NLM. National Centre for Biotechnology Information. Stat pearls. August 2021. [Accessed on 21st July 2022] https://www.ncbi.nlm.nih.gov/books/NBK534823/
3. E J Sanchez-Barcelo, M D Mediavilla, D X Tan, R J Reiter. Clinical uses of melatonin: evaluation of human trials. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. 2010. [Accessed on 22nd July 2022] https://pubmed.ncbi.nlm.nih.gov/20423309/
4. Rafarm SA. Electronic Medicines Compendium (EMC). [Revised in June 2022] [Accessed on 22nd July 2022] https://www.medicines.org.uk/emc/files/pil.10419.pdf
Useful Diagnostic Tests
- Polysomnography
Author Details
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