Introduction About NEXOSCAB LOTION

NEXOSCAB LOTION contains Cetrimide and Gamma benzene hexachloride, which belong to the group of medicines called Antiseptics and Antiparasitic drugs, respectively. It is used for the management of scabies (skin infection with itchy skin rashes caused by mites), pediculosis (infestation of scalp caused by eggs, larvae, or adults of lice), and lice.

It is advised to avoid person-to-person contact and sharing of clothes and utensils with infected persons to avoid the risk of spreading of scabies and lice. It is not recommended to use NEXOSCAB LOTION if you have fits, allergies to any of its ingredients, open, broken, or cranky skin. Before using NEXOSCAB LOTION, inform your doctor if you have HIV or AIDS, have a history of fits or conditions like a head injury, tumour in your brain or spinal cord, cirrhosis of the liver, or are heavy alcohol drinkers.

NEXOSCAB LOTION is not recommended to be used during pregnancy and breastfeeding unless it is clearly necessary. Do not use NEXOSCAB LOTION to manage a premature infant, young baby, or elderly patient. The most common side effects of using NEXOSCAB LOTION include tingling, itching, burning in the skin, and skin rashes. Consult a doctor if any of these symptoms worsen.

Uses Of NEXOSCAB LOTION

It is used to manage:

• Scabies (skin infection with itchy skin rashes caused by mites)
• Pediculosis (infestation of the scalp caused by eggs, larvae, or adults of lice)
• Lice

How NEXOSCAB LOTION Works

NEXOSCAB LOTION contains cetrimide and Gamma benzene hexachloride. Cetrimide is an antiseptic agent that kills disease-causing bacteria. Gamma benzene hexachloride is an insecticide that kills insects by damaging the brains of mites.

How to use NEXOSCAB LOTION

Apply NEXOSCAB LOTION as advised by your physician. It is for external use only. Shake well before use. Wash your hands before applying NEXOSCAB LOTION. Take adequate amounts of medicine and apply on affected areas (apply on the entire body in cases of scabies). Wash off completely with warm water after 8–12 hours.

Read the instructions within the label before using the medicine. Avoid contact with your eyes, nose, and mouth. Avoid making your skin too oily by applying creams while using NEXOSCAB LOTION. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

Side Effects Of NEXOSCAB LOTION

How To Manage Side Effects

Skin rash Or Itching

Apply a cool compress or wet cloth over the burned area. Apply moisturizers if required. Contact the doctor if it is not subsiding.

Warning & Precautions

Pregnancy

Monitoring required

NEXOSCAB LOTION is not recommended to use if you are pregnant or planning to get pregnant unless it is considered clearly necessary due to the lack of safety data. Consult your doctor before using NEXOSCAB LOTION.

Breastfeeding

Contraindicated

NEXOSCAB LOTION is not recommended for use in breastfeeding women as it may pass through the breast milk. If you use NEXOSCAB LOTION, pump your breast milk and throw away the milk for at least 24 hours after using the medicine.

During this time, feed your baby formula or breast milk you stored before you used this medicine. Consult a doctor before using it.

Liver

Use with Caution

NEXOSCAB LOTION should be used with caution if you have cirrhosis of the liver. Consult your doctor before using.

Allergy

Contraindicated

Do not use NEXOSCAB LOTION if you are allergic to cetrimide, Gamma benzene hexachloride, or any other constituents of this medicine. Consult your doctor before using NEXOSCAB LOTION.

Use In Pediatrics

Use with Caution

NEXOSCAB LOTION should be used with extreme caution in premature infants and young children. Consult a doctor before using it for children.

Use In Geriatrics

Contraindicated

NEXOSCAB LOTION is not recommended in elderly patients due to the lack of safety data. Consult a doctor before using it.

Interactions

A. Drug-drug interactions:

Before using NEXOSCAB LOTION, inform your doctor if you are taking any of the following medicines:

• Antipsychotics (medicines used to manage mental disorders) Ex. chlorpromazine, haloperidol)
• Antidepressants (medicines used to manage depression) Ex. citalopram, escitalopram)
• Theophylline (medicine used to manage wheezing and shortness of breath)
• Cyclosporin, mycophenolate mofetil, and tacrolimus capsules (medicines used to manage transplant rejection)
• Penicillin, imipenem, and quinolone antibiotics (medicines used to manage bacterial infection)
• Chloroquine sulfate (medicine used to manage malaria)
• Pyrimethamine (medicine used to manage a parasitic infection called toxoplasmosis)
• Isoniazid (medicine used to manage tuberculosis)
• Meperidine (medicine used to relieve moderate to severe pain)
• Methocarbamol (medicine used to relieve musculo-skeletal pain)
• Centrally active anticholinesterases (Ex. rivastigmine, donepezil)
• Radiographic contrast agents (Ex. iodine, barium sulfate)

Overdosage:

If you or anyone else accidentally apply too much NEXOSCAB LOTION, consult your doctor immediately.

Synopsis

More Information

FAQs About NEXOSCAB LOTION

Q: What is NEXOSCAB LOTION used for?

A: NEXOSCAB LOTION is used for the management of scabies (skin infection with itchy skin rashes caused by mites), pediculosis (infestation of scalp caused by eggs, larvae, or adults of lice), and lice. Consult a doctor before using it.

Q: How NEXOSCAB LOTION works?

A: NEXOSCAB LOTION contains cetrimide and Gamma benzene hexachloride. Cetrimide is an antiseptic agent that kills disease-causing bacteria. Gamma benzene hexachloride is an insecticide that kills insects by damaging the brains of mites.

Q: Can I apply moisturizing lotion while using NEXOSCAB LOTION?

A: No. It is better to avoid use of moisturizing lotions or creams that make your skin oily while using NEXOSCAB LOTION, as oily skin increases the chances of faster absorption of medicine and may lead to neurotoxicity (fits) in individuals.

Q: Does NEXOSCAB LOTION cause any side effects?

A: It may cause stinging, burning, redness, itching, and tingling in the skin along with skin rashes in some individuals. Consult a doctor if you experience any unusual symptoms while using this medicine.

Q: Is it safe to use NEXOSCAB LOTION during pregnancy?

A: NEXOSCAB LOTION is not recommended to use if you are pregnant or planning to get pregnant unless it is clearly necessary due to the lack of safety data. Consult your doctor before using it.

Q: Can NEXOSCAB LOTION be used in children?

A: NEXOSCAB LOTION should be used with extreme caution in premature infants and young children. Consult a doctor before using it for children.

Q: How should I use NEXOSCAB LOTION?

A: Apply NEXOSCAB LOTION as advised by your physician. It is for external use only. Shake well before use. Wash your hands before applying NEXOSCAB LOTION. Take adequate amounts of medicine and apply on affected areas (apply on the entire body in cases of scabies). Wash off completely with warm water after 8–12 hours. Read the instructions within the label before using the medicine. Avoid contact with your eyes, nose, and mouth. Avoid making your skin too oily by applying creams while using NEXOSCAB LOTION. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

Q: Who should not use NEXOSCAB LOTION?

A: Do not use NEXOSCAB LOTION if you are allergic to Cetrimide, Gamma benzene hexachloride, or if you have open, broken, or cranky skin, or are suffering from fits.

Q: What precautions must be taken while using NEXOSCAB LOTION?

A: NEXOSCAB LOTION should be used with caution if you have cirrhosis of the liver, HIV or AIDS, a history of fits or conditions like a head injury, a tumour in your brain or spinal cord, or a heavy alcohol drinking habit. Consult your doctor before using.

Q: Can I use NEXOSCAB LOTION daily?

A: Apply NEXOSCAB LOTION as advised by your physician. It is for external use only. Shake well before use. Read the instructions within the label before using the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

References

1. KD Tripathi. Antiseptics. Disinfectants and Ectoparasiticides. Essentials of Medical Pharmacology. Eighth Edition (2019). Page - 962

2. James G.H. Dinulos, MD. Lindane. Science Direct. Habif's Clinical Dermatology, 2021 [Accessed on 25th July 2024] https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/lindane

3. L M Solomon, L Fahrner, and D P West. Gamma benzene hexachloride toxicity: a review. NIH, National Library of Medicine, National Center for Biotechnology Information. PubMed.gov. March 1977. [Accessed on 25th July 2024] https://pubmed.ncbi.nlm.nih.gov/65941/

4. Lindane Lotion. United States Food and Drug Administration (USFDA) [Accessed on 25th July 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/006309lotionlbl.pdf

5. Cetrimide + Gamma benzene hexachloride. Leeford pharma [Accessed on 25th July 2024] https://www.leeford.in/product/1286/neoscab-lotion

6. Cetrimide + Gamma benzene hexachloride. Ikon remedies [Accessed on 25th July 2024] https://www.ikonremedies.com/product/gamabion-lotion/

7. Cetrimide + Gamma benzene hexachloride. Orion Life Science [Accessed on 25th July 2024] http://www.orionlifeindia.com/gamma-benzene-hexachloride-cetrimide-emulsion-5043668.html

8. Cetrimide + Gamma benzene hexachloride. Alpha drugs [Accessed on 25th July 2024] https://www.alphadrug.in/product/scabnyl-lotion/

9. Cetrimide + Gamma benzene hexachloride. Talent India Pharmaceuticals [Accessed on 25th July 2024] https://talentindia.com/html/dermatology-and-cosmetology/

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Serum Electrolytes/ Electrolytes Profile
• Complete Women Checkup
• Women Health Checkup - Essential
• Full Body Checkup – Gold
• Elderly Checkup - Female
• Elderly Checkup – Male
• Full Body Checkup – Silver

Author Details

Written By Dr. N. Sai Swaroop - Pharm.D

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 26 Jul 2024 | 05:47 PM(IST)