Introduction About KOFFGO NEW SYRUP

KOFFGO NEW SYRUP is a combination of Bromhexine, Chlorpheniramine maleate and Guaifenesin which belongs to the group of medicines called Mucolytics, Antihistamines and Nasal decongestants. It is used for symptomatic relief of productive cough.

Avoid alcohol consumption while taking KOFFGO NEW SYRUP as it may increase drowsiness. KOFFGO NEW SYRUP is not recommended for use in patients with severe hypertension, severe coronary artery disease or porphyria. KOFFGO NEW SYRUP should be used with caution in patients with asthma, bronchitis, bronchiectasis or chronic lung disorders; severe liver or kidney disease; hypotension; ischaemic heart disease or cardiovascular collapse; fits; diabetes mellitus; a peptic ulcer; and glaucoma.

KOFFGO NEW SYRUP is not recommended for use in pregnancy unless considered necessary. KOFFGO NEW SYRUP is not recommended for breastfeeding women unless considered necessary, as it may pass through breast milk. In children aged 2 to 12 years, KOFFGO NEW SYRUP should be used with caution.KOFFGO NEW SYRUP should be used with caution in patients over the age of 65.

The most common side effects of taking KOFFGO NEW SYRUP are drowsiness and sedation, change in concentration, incoordination, dizziness, headache, blurred vision, nausea, vomiting, dry mouth and fatigue. If your symptoms worsen, consult your doctor.

Uses Of KOFFGO NEW SYRUP

• For symptomatic relief of productive cough

How KOFFGO NEW SYRUP Works

KOFFGO NEW SYRUP is a cough suppressant, whereas Bromhexine is a mucolytic that thins and breaks down phlegm, making it easier to cough up. Chlorpheniramine maleate is an antihistamine that blocks the binding of histamine (responsible for allergic reactions such as sneezing, watery and itchy eyes and a runny nose) to histamine H1 receptors, thus managing allergic reactions. Guaifenesin is an expectorant that relieves chest congestion, making breathing easier by loosening and clearing phlegm from the lungs and making it easier to cough up.

How to use KOFFGO NEW SYRUP

Take KOFFGO NEW SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

Side Effects Of KOFFGO NEW SYRUP

How To Manage Side Effects

Dizziness and drowsiness:

Try to rest and relax. Get enough sleep. Do not drive or operate any machines if you feel dizzy or drowsy. Do not consume alcohol, as it increases dizziness or drowsiness. Contact your doctor if your dizziness or drowsiness does not improve.

Headache:

Rest and relax. Drink plenty of fluids, such as water or electrolytes and apply a pain-relieving balm on the head if necessary. Do not consume alcohol. Contact your doctor if the headache worsens.

Nausea, vomiting:

Eat simple meals. Avoid eating oily or spicy foods. Contact your doctor if nausea and vomiting worsen.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices, to keep you hydrated. Take no medication on your own to manage diarrhea. Contact your doctor if your diarrhoea does not improve.

Stomach pain:

Try to rest and relax. Consume small meals regularly. Keep a heating pad on your stomach. Contact your doctor if your stomach pain worsens.

Skin rash:

Avoid a hot water bath as it irritates the skin and does not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturisers to soothe and hydrate the affected area. Contact your doctor if the rashes worsen.

Warning & Precautions

Pregnancy

KOFFGO NEW SYRUP is not recommended for use in pregnancy unless considered necessary. Contact your doctor before taking it.

Breastfeeding

KOFFGO NEW SYRUP is not recommended for use in breastfeeding women unless considered clearly necessary as it may pass through the breast milk. Contact your doctor before taking it.

Driving and Using Machines

Do not drive or operate machines if you feel drowsiness, dizziness and blurred vision after taking KOFFGO NEW SYRUP.

Alcohol

Avoid alcohol consumption while taking KOFFGO NEW SYRUP as it may increase drowsiness.

Kidney

KOFFGO NEW SYRUP should be used with caution in patients with severe kidney disease. Contact your doctor before taking it.

Liver

KOFFGO NEW SYRUP should be used with caution in patients with severe liver disease. Contact your doctor before taking it.

Allergy

Do not use KOFFGO NEW SYRUP if you are allergic to Bromhexine, Chlorpheniramine maleate, Guaifenesin or other ingredients of the medicine.

Lungs

KOFFGO NEW SYRUP should be used with caution in patients with asthma, bronchitis, bronchiectasis or chronic lung disorders. Contact your doctor before taking it.

Heart Disease

KOFFGO NEW SYRUP is not recommended for use in patients with severe hypertension and severe coronary artery disease and should be used with hypotension, ischaemic heart disease or cardiovascular collapse. Contact your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking KOFFGO NEW SYRUP, inform your doctor if you are taking any of the following medicine:

• monoamine oxidase (MAO) inhibitors Ex. moclobemide (medicines used for depression)
• antibiotics such as ampicillin, amoxicillin, erythromycin or oxytetracycline (medicines used for bacterial infections)
• phenytoin (medicines used to manage fits)
• benzodiazepines Ex. diazepam, lorazepam (medicines used for anxiety, fits)
• paracetamol (medicines used for pain and fever)

Overdosage:

If you or anyone else accidentally take too much of KOFFGO NEW SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting, diarrhoea, indigestion, drowsiness, fever, ataxia, excitement, tremors, psychosis, hallucinations and fits, dilated pupils, dry mouth and facial flushing. Cardiorespiratory collapse, coma and even death.

Synopsis

More Information

• Keep KOFFGO NEW SYRUP out of the sight and reach from children
• Store KOFFGO NEW SYRUP below 30°C

FAQs About KOFFGO NEW SYRUP

Q: What is KOFFGO NEW SYRUP and how does it work?

A: KOFFGO NEW SYRUP is a combination of bromhexine, chlorpheniramine maleate and guaifenesin, which belongs to the group of medicines called mucolytics, antihistamines and nasal decongestants. It is used to manage the symptoms of a productive cough.

Q: Can I use KOFFGO NEW SYRUP with children?

A: Yes. In children aged 2 to 12 years, KOFFGO NEW SYRUP should be used with caution. Contact your doctor before taking it.

Q: Is KOFFGO NEW SYRUP safe during pregnancy?

A: No. KOFFGO NEW SYRUP is not recommended for use in pregnancy unless clearly necessary. Contact your doctor before taking it.

Q: Does KOFFGO NEW SYRUP cause drowsiness?

A: Yes. KOFFGO NEW SYRUP may cause drowsiness. Try to rest and relax. Get enough sleep. Do not drive or operate any machines if you feel drowsy. Do not consume alcohol, as it increases drowsiness. Contact your doctor if your drowsiness does not improve.

Q: What are the side effects of taking KOFFGO NEW SYRUP?

A: The most common side effects of taking KOFFGO NEW SYRUP are drowsiness and sedation, change in concentration, incoordination, dizziness, headache, blurred vision, nausea, vomiting, dry mouth and fatigue. If your symptoms worsen, consult your doctor.

References

1. KD Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 219, 220, 218.

2. Delpharm Reims S.A.S. Health Products Regulatory Authority (HPRA). Revised in September 2021] [Accessed on 23rd July 2022] https://www.hpra.ie/img/uploaded/swedocuments/4550f813-c219-4e0a-b51a-5e6ed8a8e9f0.pdf

3. Farmaclair. Electronic Medicines Compendium (EMC). Revised in March 2022] [Accessed on 23rd July 2022] https://www.medicines.org.uk/emc/files/pil.3928.pdf

4. Reckitt Benckiser Healthcare (UK) Limited. Electronic Medicines Compendium (EMC). Revised in May 2016] [Accessed on 23rd July 2022] https://www.medicines.org.uk/emc/files/pil.8440.pdf

5. Reckitt Benckiser Healthcare (UK) Limited. Health Products Regulatory Authority (HPRA). [Accessed on 23rd July 2022] http://www.hpra.ie/img/uploaded/swedocuments/33802379-fb3b-42e2-a664-44a2ae2b4657.pdf

6. Cheston Expectorant (Bromhexine, Chlorpheniramine maleate and Guaifenesin). [Revised in November 2013] [Accessed on 23rd July 2022] https://www.ciplamed.com/content/Cheston-expectorantdt