Introduction About MYOSONE 50MG TABLET

MYOSONE 50MG TABLET contains Eperisone, which belongs to the group of medicines called Muscle Relaxants. It is used to manage and improve the myotonic condition of the muscles caused by neck-shoulder arm syndrome (a condition causing muscle pain and stiffness in the neck, arm, and shoulder region), scapulohumeral periarthritis (a condition causing muscle pain and stiffness in the shoulder joint), and low back pain (a painful condition affecting the lower region of the spine due to a muscle or ligament injury).

The myotonic condition causes wasting and weakness of the muscle when its functional ability to relax is impaired. It is also used to manage spastic paralysis (loss of muscle function along with pain and muscle stiffness) caused by a spinal or neurological disorder, trauma, cerebral palsy, tumour in the spine, etc.

MYOSONE 50MG TABLET should be used with caution in patients with liver function disorders. MYOSONE 50MG TABLET is generally not recommended for use during pregnancy unless recommended by your doctor. MYOSONE 50MG TABLET is not recommended for use by breastfeeding women. Its safety and efficiency for use in children have not been established. Consult your doctor for advice before taking MYOSONE 50MG TABLET.

The most common side effects of taking MYOSONE 50MG TABLET may include weakness, light-headedness, fatigue, sleepiness, insomnia, headache, nausea, vomiting, loss of appetite, abdominal pain, diarrhea, constipation, and thirst. Consult your doctor if any of the above side effects worsen or persist.

Uses Of MYOSONE 50MG TABLET

• Manage and improves the myotonic condition (wasting and weakness) of the muscle
• Manage spastic muscle paralysis

How MYOSONE 50MG TABLET Works

MYOSONE 50MG TABLET works by blocking the voltage-gated sodium channel in the brain stem. As a result, it stops nerve signals and aids in the relaxation of muscles.

How to use MYOSONE 50MG TABLET

Take MYOSONE 50MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose, frequency, and duration of management for you depending upon your age, body weight, and disease condition.

Side Effects Of MYOSONE 50MG TABLET

Warning & Precautions

Pregnancy

MYOSONE 50MG TABLET is generally not recommended for use during pregnancy unless recommended by your doctor. Contact your doctor before taking MYOSONE 50MG TABLET.

Breastfeeding

MYOSONE 50MG TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking MYOSONE 50MG TABLET.

Driving and Using Machines

Do not drive or operate any machines if you feel weakness, sleepiness, or light-headedness after taking MYOSONE 50MG TABLET.

Liver

MYOSONE 50MG TABLET should be used with caution in patients with a disorder of liver function. Consult your doctor before taking MYOSONE 50MG TABLET.

Allergy

MYOSONE 50MG TABLET is not recommended for use if you are allergic to Eperisone.

Interactions

A. Drug-Drug interactions:

• methocarbamol (a medicine used to manage muscle spasms or stiffness)

Overdosage:

If you or anyone else have accidentally taken too much of MYOSONE 50MG TABLET, consult your doctor immediately or visit the nearby hospital as overdosage can result in abnormal heart function.

Synopsis

More Information

• keep MYOSONE 50MG TABLET out of reach from children
• store at room temperature

FAQs About MYOSONE 50MG TABLET

Can MYOSONE 50MG TABLET be used to manage muscle pain?

Yes, MYOSONE 50MG TABLET relieves muscle pain and relaxes the muscle by blocking the voltage-gated sodium channel in the brain stem, thereby stopping the conduction of nerve signals.

Can MYOSONE 50MG TABLET be used in pregnant and nursing mothers?

MYOSONE 50MG TABLET is generally not recommended for use during pregnancy unless considered necessary by your doctor. MYOSONE 50MG TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking it.

Can MYOSONE 50MG TABLET cause dizziness?

Yes, MYOSONE 50MG TABLET may cause dizziness. If you start to feel dizzy, sit down immediately or lay down in a quiet and dark area with your eyes closed. Consult your doctor if the symptom worsens or persists.

Can MYOSONE 50MG TABLET be taken by patients with liver disease?

MYOSONE 50MG TABLET should be used with caution in patients having a liver function disorder, as this medicine may aggravate the existing condition. Consult your doctor for advice.

How does MYOSONE 50MG TABLET work?

MYOSONE 50MG TABLET works by blocking the voltage-gated sodium channel in the brain stem. As a result, it stops nerve signals and aids in the relaxation of muscles.

References

1. Kamran Ahmed, Muhammad Harris Shoaib, Rabia Ismail Yousuf, Fahad Siddiqui, Faaiza Qazi, Javeria Iftikhar, Farrukh Rafiq Ahmed, and Muhammad Iqbal Nasiri. Comparative pharmacokinetics of osmotic-controlled and immediate-release Eperisone tablet formulation in healthy human subjects using a sensitive plasma LC-ESI-MS/MS method. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. October 2020. [Accessed 7th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002734/

2. Takeshi Yamagiwa, Seiji Morita, Mari Amino, Naoya Miura, Takeshi Saito, Sadaki Inokuchi. Serum concentration of eperisone hydrochloride correlates with QT interval. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. January 2014. [Accessed 7th June 2022] https://pubmed.ncbi.nlm.nih.gov/24135462/

3. Rizaldy Taslim Pinzon, Vincent Ongko Wijaya, Dessy Paramitha, and Raymondus Ranga Bagaskara. Effects of Eperisone Hydrochloride and Non-Steroid Anti-Inflammatory Drugs for Acute Non-Specific Back Pain with Muscle Spasm: A Prospective, Open-Label Study. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. November 2020. [Accessed 7th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678690/

4. Eisai Co., Ltd. [Revised in July 2009] [Accessed 7th June 2022] http://www.shijiebiaopin.net/upload/product/201082521391314.pdf