INTRODUCTION

MUCOMIX ET 600MG contains Acetyl Cysteine which belongs to the group of medicines called Mucolytics. It is used in adults to manage acute airway diseases such as bronchitis (inflammation of the lining of bronchial tubes which carries air to the lungs), emphysema (disorder affecting the alveoli (tiny air sacs) of the lungs), mucoviscidosis (inherited life-threatening disorder that damages the lungs and digestive system) and bronchiectasis (condition in which the lung airways become damaged and making it hard to clear the mucus).

MUCOMIX ET 600MG is not recommended for use in patients who are allergic to acetylcysteine. It is also not recommended for use in patients with bronchial asthma. Before taking MUCOMIX ET 600MG, inform your doctor if you have stomach ulcers, liver diseases (such as non-alcoholic fatty acid disease) and chronic kidney disease.

It should be used with caution in pregnant and breastfeeding women only if it is clearly advised by the doctor. MUCOMIX ET 600MG is not recommended for use in children and adolescents (below 18 years of age) and it should be used with caution in elderly patients.

The most common side effects associated with the use of MUCOMIX ET 600MG are nausea and vomiting. Consult your doctor if any of the side effect worsens.

USES OF MUCOMIX ET 600MG

Used in adults:

• to manage airway diseases (such as bronchitis, emphysema, mucoviscidosis and bronchiectasis)

HOW MUCOMIX ET 600MG WORKS

MUCOMIX ET 600MG works by enhancing airway secretions and mucociliary function (a defence mechanism of lungs that promote movement and removal of excess mucus) which causes the mucus (phlegm) to become less sticky resulting in its easy removal through cough, thus helps in manageing the airway diseases.

DIRECTIONS FOR USE

Take MUCOMIX ET 600MG as advised by your physician. Dissolve the medicine in half a glass of water and drink the solution immediately. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF MUCOMIX ET 600MG

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Take MUCOMIX ET 600MG with or just after meals. Stick to simple meals. Avoid eating oily, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.

Diarrhoea:

Drink lot of fluids such as water. Avoid eating high-fat or spicy foods. Do not consume any medicine on your own to manage diarrhoea without consulting your doctor.

Stomach pain:

Try to rest and relax. Eat and drink slowly or try to have smaller meals more frequently. Keep a heat pad on your stomach. If the symptom does not improve, consult your doctor.

Headache:

Drink ample amount of water. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interactions

Before taking MUCOMIX ET 600MG, inform your doctor, if you are taking any of the following medicines:

• cough suppressants (medicines used to suppress cough reflex) Ex. benzonatate
• nitroglycerin (used to manage angina pectoris)
• activated charcoal (used to manage traveller’s diarrhoea)

Overdosage:

If you or anyone else accidentally takes too much of MUCOMIX ET 600MG, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting, and diarrhoea.

SYNOPSIS

MORE INFORMATION

• Keep the medicine out of reach of children
• Store MUCOMIX ET 600MG at room temperature

FAQs ABOUT MUCOMIX ET 600MG

What is MUCOMIX ET 600MG used for?

MUCOMIX ET 600MG is used in adults as a mucolytic agent (phlegm loosening medicine) to manage airway diseases such as bronchitis, emphysema, mucoviscidosis (cystic fibrosis) and bronchiectasis. Consult your doctor before taking MUCOMIX ET 600MG.

What happens if you take more MUCOMIX ET 600MG than your required dose?

If you or anyone else accidentally takes too much of MUCOMIX ET 600MG, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting and diarrhoea.

Is it safe to use MUCOMIX ET 600MG in pregnant and breastfeeding women?

MUCOMIX ET 600MG should be used with caution in pregnant and breastfeeding women only if it is clearly advised by your doctor. Consult your doctor before taking MUCOMIX ET 600MG if you are pregnant or planning to get pregnant or breast-feeding your child.

Who should avoid taking MUCOMIX ET 600MG?

MUCOMIX ET 600MG is not recommended for use in patients who are allergic to acetylcysteine and in patients who suffer from bronchial asthma. It is also not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking the medicine.

What if I forget to take a dose of MUCOMIX ET 600MG?

If you forget to take a dose of MUCOMIX ET 600MG, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take MUCOMIX ET 600MG twice to make up for a forgotten dose.

Does MUCOMIX ET 600MG cause liver damage?

MUCOMIX ET 600MG should be used with caution in patients with liver diseases such non-alcoholic fatty acid disease (liver condition that leads to build-up of fat in liver in non-alcoholic individuals) as it may cause serious liver damage in such patients. Consult your doctor before taking MUCOMIX ET 600MG.

REFERENCES

1. Laurence Brunton. Pulmonary Pharmacology. Goodman and Gillman’s The Pharmacological Basics of Therapeutics. Twelfth Edition. 2011. Page – 1057.

2. Micaely Cristina dos Santos Tenorio, Nayara Gomes Graciliano, Fabiana Andrea Moura, Alane Cabral Menezes de Oliveira, Marilia Oliveira Fonseca Goulart. N-Acetylcysteine (NAC): Impacts on Human Health. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. June 2021. [Accessed on 22nd August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234027/

3. Manouchehr Khoshbaten, Akbar Aliasgarzadeh, Koorosh Masnadi, Mohammad K Tarzamani, Sara Farhang, Hosain Babaei, Javad Kiani, Maryam Zaare, Farzad Najafipoor. N-Acetylcysteine Improves Liver Function in Patients with Non-Alcoholic Fatty Liver Disease. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. March 2010. [Accessed on 22nd August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270338/

4. Minyuan Ye, Weiyuan Lin, Jing Zheng, Shaopeng Lin. N-acetylcysteine for chronic kidney disease: a systematic review and meta-analysis. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. April 2021. [Accessed on 22nd August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129408/

5. Mark F. McCarty and James J. DiNicolantonio. An increased need for dietary cysteine in support of glutathione synthesis may underlie the increased risk for mortality associated with low protein intake in the elderly. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. October 2015. [Accessed on 22nd August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129408/

6. Elara Pharmaceuticals Limited. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 22nd August 2022] https://www.medicines.org.uk/emc/files/pil.8576.pd

USEFUL DIAGNOSTIC TESTS

• Lung Function Test