Introduction About MUCOBREX LC SYRUP

MUCOBREX LC SYRUP is a combination of Chlorpheniramine and Levodropropizine which belongs to the group of medicines called Antihistamines and Cough suppressants respectively. It is used to manage dry cough due to various reasons. It is also used to manage allergic cough, hay fever, common cold, watery eyes, itchy throat/skin, rhinitis, urticaria.

Avoid consumption of alcohol while taking this medicine as this may lead to unwanted effects. MUCOBREX LC SYRUP is not recommended for use in patients with severe liver disease. Contact your doctor before taking.

Before taking MUCOBREX LC SYRUP inform your doctor if you have lung, kidney, liver or heart disease.

MUCOBREX LC SYRUP is generally not recommended for use in pregnancy. Contact your doctor before taking. MUCOBREX LC SYRUP is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking.

MUCOBREX LC SYRUP is not recommended for use in children under 6 years of age. Contact your doctor before taking.

MUCOBREX LC SYRUP should be used with caution in elderly patients (aged 65 years or above). Contact your doctor before taking.

The most common side effects of this medicine are sedation, somnolence, exhaustion, constipation, vomiting, dry mouth, attention deficit, abnormal coordination, dizziness. Contact your physician if any of the side effects worsen.

Uses Of MUCOBREX LC SYRUP

• Used to manage dry cough

How MUCOBREX LC SYRUP Works

MUCOBREX LC SYRUP helps to manage dry cough, where Chlorpheniramine is an antihistamine works by blocking the histamine H1 receptor and manages the release of histamine (which normally produces symptoms of sneezing, itching, watery eyes, and runny nose) and Levodropropizine is a cough suppressant which relieves cough by activity on the cough centre in the brain.

How to use MUCOBREX LC SYRUP

Take MUCOBREX LC SYRUP as advised by your physician. Shake well before use. Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of MUCOBREX LC SYRUP

How To Manage Side Effects

Nausea or Vomiting:

Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods.

Constipation:

Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals and drink water. Exercise regularly.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Contact your doctor if the symptom did not improve.

Warning & Precautions

Pregnancy

MUCOBREX LC SYRUP is generally not recommended for use in pregnancy. Contact your doctor before taking.

Breastfeeding

MUCOBREX LC SYRUP is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking.

Driving and Using Machines

Do not drive or operate any machines if you feel drowsiness after taking MUCOBREX LC SYRUP.

Alcohol

Avoid consumption of alcohol while taking MUCOBREX LC SYRUP as it may lead to unwanted effects.

Kidney

MUCOBREX LC SYRUP should be used with caution in patients with severe kidney disease. Contact your doctor before taking.

Liver

MUCOBREX LC SYRUP is not recommended for use in patients with severe liver disease. Contact your doctor before taking.

Allergy

Do not take MUCOBREX LC SYRUP if you are allergic to Chlorpheniramine, Levodropropizine, or to other ingredients of this medicine.

Lungs

MUCOBREX LC SYRUP should be used with caution in patients with lung diseases such as bronchitis, bronchiectasis, asthma or chronic lung disorders (difficulty in breathing and cough). Contact your doctor before taking.

Heart Disease

MUCOBREX LC SYRUP should be used with caution in patients with heart diseases or heart rhythm disorders. Contact your doctor before taking  

Interactions

A. Drug - Drug interactions:

Inform your physician if you are taking any of the following medicine:

• alprazolam, bromezapam, diazepam, clonazepam, clorazepate, chlordiazepoxide (medicines used to manage anxiety, fits, insomnia)
• buspirone, hydroxyzine (medicines used for anxiety)
• zolpidem (medicines used to manage insomnia)
• isocarboxazid, phenelzine, tranylcypromine and tricyclic antidepressants like amitriptyline, desipramine (medicines used for depression)
• linezolid (medicines used to manage bacterial infections)

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep out of reach of children
• Store MUCOBREX LC SYRUP below 25°C

FAQs About MUCOBREX LC SYRUP

For what conditions MUCOBREX LC SYRUP is used?

MUCOBREX LC SYRUP is used for the management of dry cough. It is also used to manage allergic cough, hay fever, common cold, watery eyes, itchy throat/skin, rhinitis, urticaria. Contact your doctor before taking the medicine.

How MUCOBREX LC SYRUP work?

MUCOBREX LC SYRUP helps to manage dry cough, where Chlorpheniramine is an antihistamine works by blocking the histamine H1 receptor and manages the release of histamine (which normally produces symptoms of sneezing, itching, watery eyes, and runny nose) and Levodropropizine is a cough suppressant which relieves cough by activity on the cough centre in the brain.

What are the possible side effects of taking MUCOBREX LC SYRUP?

The most common side effects of this medicine are sedation, somnolence, exhaustion, constipation, vomiting, dry mouth, attention deficit, abnormal coordination, dizziness. Contact your physician if any of the side effects worsen.

Does MUCOBREX LC SYRUP cause drowsiness?

Yes. MUCOBREX LC SYRUP may cause drowsiness. Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Contact your doctor if the symptom did not improve.

Can I use MUCOBREX LC SYRUP in children?

Yes. MUCOBREX LC SYRUP should be used with caution in children aged above 6 years. Contact your doctor before taking the medicine.

References

1. K.D. Tripathi. Drugs for cough and bronchial asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 220.

2. Bethesda (MD). Levodropropizine. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 18th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Levodropropizine

3. Alessandro Zanasi, Luigi Lanata, Giovanni Fontana, Federico, Saibene, Peter Dicpinigaitis, and Francesco De Blasio. Uses of Levodropropizine. National Institute of Health. NLM. National Centre for Biotechnology Information. Pubmed.gov. May 2015. [Accessed on 18th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472410/

4. Berko ilac, Kimya San. A.S. Chlorpheniramine and Levodropropizine. [Revised in February 2016] [Accessed on 18th June 2022] http://berkoilac.com.tr/wp-content/uploads/2017/05/dropolev-syrup-en.pdf

5. GlaxoSmithKline Consumer Healthcare (UK). Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed on 18th June 2022] https://www.medicines.org.uk/emc/files/pil.3928.pdf

6. Chlorpheniramine and Levodropropizine. Green Cross Remedies. [Accessed on 18th June 2022] http://www.greencrossindia.com/p/astagon-clv-cough-syrup.html

7. Chlorpheniramine and Levodropropizine.  Orion Life science. [Accessed on 18th June 2022] https://www.orionlifes.com/product/levodropropizine-and-chlorpheniramine-maleate-syrup/

8. Levodropropizine. Mims.com. [Accessed on 18th June 2022] https://www.mims.com/philippines/drug/info/levopront?type=full

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 17 Dec 2022 | 06:13 PM(IST)