Introduction About MOXIZEST OPHTHALMIC SOLUTION

MOXIZEST OPHTHALMIC SOLUTION contains Moxifloxacin which belongs to the group of medicines called Antibiotics. It is used to manage bacterial conjunctivitis and other eye infections.

Bacterial conjunctivitis is the infection of the transparent membrane (conjunctiva) that lines the eyelid and covers the white part of your eyeball. Symptoms of bacterial conjunctivitis include pain, discomfort, redness, itching, irritation, and watering of the eyes.

Patients should be advised not to wear contact lenses if they have signs and symptoms of bacterial conjunctivitis.

MOXIZEST OPHTHALMIC SOLUTION should be used with caution in pregnant women or if you think you may be pregnant and a breastfeeding woman. Consult your doctor before using.

MOXIZEST OPHTHALMIC SOLUTION is not recommended for use in newborns and it should be used with caution in children and adolescents. Your doctor will prescribe the right dose depending on your child’s age and body weight.

MOXIZEST OPHTHALMIC SOLUTION should be used with caution in elderly patients above 65 years of age. The common side effects are eye pain or irritation. Consult your doctor if the above symptoms does not improve.

Uses Of MOXIZEST OPHTHALMIC SOLUTION

• Used to manage bacterial conjunctivitis and other eye infections

How MOXIZEST OPHTHALMIC SOLUTION Works

MOXIZEST OPHTHALMIC SOLUTION works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV which are required for DNA replication and transcription resulting in cell death. This manages the bacterial cells from dividing and repairing and destroys them.

How to use MOXIZEST OPHTHALMIC SOLUTION

Use MOXIZEST OPHTHALMIC SOLUTION exactly as directed by your physician. Instil the medicine as advised by the physician. It is for ophthalmic use only. Your doctor will prescribe the right dose depending on your age, body weight and severity of the infection.

Side Effects Of MOXIZEST OPHTHALMIC SOLUTION

How To Manage Side Effects

Vomiting:

Stick to simple meals. Try to Avoid oil rich or spicy foods, sugary snacks, and drinks. Try to drink liquid slowly along with your meals, or in between meals. Consult your doctor if your symptom is not improving.

Headache:

Apply a hot or cold-water bag on your head. Try to take rest in a quiet and dark room. Drink tea or coffee. Massage on the scalp or head with mild pressure. Consult your doctor for advice.

Eye itching or Burning:

Close your eyes and relax for some time. Place an ice pack over the eyes for a few minutes. Avoid watching mobile phones, systems, laptops, or any other light sources which might irritate your eyes. If the symptom persists or worsens, contact your doctor.

Warning & Precautions

Pregnancy

MOXIZEST OPHTHALMIC SOLUTION should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus. Consult your doctor before using.

Breastfeeding

There are no adequate and well-controlled studies on the use of MOXIZEST OPHTHALMIC SOLUTION in breastfeeding women. Consult your doctor before using.

Driving and Using Machines

Do not drive or handle any machines while using this MOXIZEST OPHTHALMIC SOLUTION, since it may cause blurred vision.

Allergy

Do not use MOXIZEST OPHTHALMIC SOLUTION if you are allergic to Moxifloxacin or any other ingredients of this medicine.

Interactions

A. Drug - Drug interactions:

Inform your doctor if you are taking, using or have recently taken any other medicines, including prescription, non-prescription and herbal supplements.

Overdosage:

If you or anyone else accidentally use too much of MOXIZEST OPHTHALMIC SOLUTION, consult your doctor immediately or visit the nearby hospital. Wash your eyes and rinse it all out with warm water.

Synopsis

More Information

• Keep out of reach of children
• Store at room temperature

FAQs About MOXIZEST OPHTHALMIC SOLUTION

What is MOXIZEST OPHTHALMIC SOLUTION and why it is given?

MOXIZEST OPHTHALMIC SOLUTION contains moxifloxacin which is used to manage bacterial conjunctivitis and other eye infections.

How does MOXIZEST OPHTHALMIC SOLUTION works?

MOXIZEST OPHTHALMIC SOLUTION works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV which are required for DNA replication and transcription resulting in cell death. This manages the bacterial cells from dividing and repairing and destroys them.

How to use MOXIZEST OPHTHALMIC SOLUTION?

Always use this MOXIZEST OPHTHALMIC SOLUTION directed by your physician. It is for ophthalmic use only. Wash your hands thoroughly. Gently pull your lower eyelid gently and instil one or two drops of this medicine inside the lower eyelid. Close your eyelid and gently press on the inner corner of your eyelid for 2-3 minutes to manage the drainage of the solution into your nose and throat. If required, repeat the same for the other eye.

Does MOXIZEST OPHTHALMIC SOLUTION cause eye irritation?

Yes, it may cause itching and burning sensation in the eyes in some patients. Close your eyes and relax for some time. Place an ice pack over the eyes for a few minutes. Avoid watching mobile phones, systems, laptops, or any other light sources which might irritate your eyes. If the symptom persists or worsens, contact your doctor.

Can MOXIZEST OPHTHALMIC SOLUTION be used in children?

MOXIZEST OPHTHALMIC SOLUTION is not recommended for use in infants below 1 year of age. Consult your doctor for advice before using the medicine.

References

1. KD. Tripathi. Sulfonamides, Cotrimoxazole and Quinolones. Essentials of medical pharmacology. Eighth edition. 2013. Page – 764.

2. Darlene Miller. Review of moxifloxacin hydrochloride ophthalmic solution in the treatment of bacterial eye infections. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. March 2008. [Accessed 29th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698721/

3. Panel Barry A.SchlechPhD, EduardoAlfonsoMD. Overview of the Potency of Moxifloxacin Ophthalmic Solution 0.5% (VIGAMOX®). Science Direct. November 2005. [Accessed 29th June 2022] https://www.sciencedirect.com/science/article/abs/pii/S0039625705000524

4. Novartis Pharmaceuticals UK Limited. S.A. Alcon-Couvreur N.V. Electronic Medicines Compendium (EMC) [Revised in October 2020] [Accessed 29th June 2022] https://www.medicines.org.uk/emc/files/pil.5721.pdf

5. Alcon Laboratories, Inc. U.S. Food & Drug Administration [Revised in July 2011] [Accessed 29th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021598s017lbl.pdf

6. Maxim gel. His eyeness ophhalmics. [Accessed 29th June 2022] https://hiseyeness.com/shop/product/maxim-gel/

7. Mocare gel. Care group. [Accessed 29th June 2022] https://caregroupiol.com/products/ophthalmic-solutions/pharmaceutical-products/mocare/

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 21 Oct 2022 | 10:20 AM(IST)