Introduction About MEREX 1000MG INJECTION

MEREX 1000MG INJECTION is also used to manage psoriasis, which is severe and not manageable by other managements.

Before receiving MEREX 1000MG INJECTION, it is recommended to inform the doctor about your medical and family history, including the list of medicines (prescription, non-prescription medicines, and herbal medicines) that are being taken.

Also, MEREX 1000MG INJECTION is not recommended to be administered to pregnant and nursing women, women planning pregnancy, those who drink huge amounts of alcohol, or patients suffering from liver and kidney impairment.

Caution must be exercised by patients suffering from lung disorders, blood disorders, and gastric disorders before receiving MEREX 1000MG INJECTION.

Care must be taken to avoid taking products containing caffeine, such as black tea, coffee, and cold drinks, while receiving MEREX 1000MG INJECTION.

The common side effects that can be experienced after receiving MEREX 1000MG INJECTION are headache, nausea, vomiting, dizziness, and altered levels of blood cells. Consult a doctor if any of the above side effects worsen after receiving MEREX 1000MG INJECTION.

• acute lymphocytic lymphoma (ALL)
• meningeal leukemia
• Non-Hodgkin’s Lymphoma
• bone cancer (osteogenic sarcoma)
• advanced breast cancer
• recurrent and aggressive cancer of the head and neck region
• advanced cancer of the urinary bladder
• lung cancer (bronchogenic carcinoma)
• choriocarcinoma
• severe form of psoriasis

Before receiving MEREX 1000MG INJECTION, inform your doctor if you are taking any of the following medicines:

• medicines used to manage diabetes (Ex. sulphonylureas)
• medicines used to manage various skin and autoimmune diseases (Ex. para-aminobenzoic acid)
• medicines used to remove excess fluid and water from the body (Ex. frusemide)
• medicines used to manage epilepsy (Ex. phenytoin)
• medicines used in organ transplantation (Ex. azathioprine)
• medicines used as supplements
• medicines used to manage pain and inflammation (Ex. aspirin)
• other medicines used to manage rheumatoid arthritis and psoriasis (Ex. leflunomide, phenylbutazone, or amidopyrine)
• medicines used to manage gout (Ex. probenecid, allopurinol)
• medicines used to manage asthma (Ex. theophylline)
• medicines used to manage increased cholesterol levels (Ex. cholestyramine)
• medicines used to manage heart problems (Ex. amiodarone)
• medicines used to manage Crohn’s disease (Ex. sulfasalazine)
• medicines used to manage severe heartburn or ulcers (Ex. omeprazole)
• medicines used to manage skin conditions (Ex. acitretin)
• medicines used to manage malaria (Ex. pyrimethamine)
• medicines used to manage severe conditions such as psoriasis, along with ultraviolet light in PUVA therapy (Ex. methoxsalen)
• medicines used to manage infections (Ex. amoxicillin, ciprofloxacin)
• medicines used as vaccinations (Ex. live vaccines such as the MMR vaccine)

B. Drug-Food interactions:

It is recommended to avoid the consumption of drinks containing caffeine, such as black tea, coffee, and soft drinks, to manage dehydration.

Overdosage:

MEREX 1000MG INJECTION will be administered only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. If you experience any unusual reactions, contact your doctor immediately. Symptoms of overdosage with MEREX 1000MG INJECTION are nausea and vomiting, along with the development of mouth sores, black tarry or bloody stools, and severe infections.

A: MEREX 1000MG INJECTION is used to manage various cancers such as acute lymphocytic lymphoma (ALL), meningeal leukemia, Non-Hodgkin’s Lymphoma, cancer of the ovary, cancer of the head and neck region, breast cancer, cancer of the cervix, cancer of the lungs, cancer of the bones, cancer of skin-originated T-cell Lymphoma, cancer of the bladder, and various other cancers that are severe and unmanageable by conventional therapy. MEREX 1000MG INJECTION is also used to manage psoriasis that is not manageable by other managements and is very severe.

Q: Can I receive MEREX 1000MG INJECTION in pregnancy?

A: MEREX 1000MG INJECTION is not recommended for use in pregnant women and/or in women who are planning pregnancy because it can be harmful for the foetus (a growing baby in the womb). Consult your doctor before receiving it.

Q: Can I receive MEREX 1000MG INJECTION if I am breast-feeding a baby?

A: MEREX 1000MG INJECTION is not recommended for nursing mothers due to a lack of safety data. Consult your doctor before receiving it.

Q: Can MEREX 1000MG INJECTION be used by children?

A: MEREX 1000MG INJECTION is recommended to be used with caution in children. Consult the doctor before receiving MEREX 1000MG INJECTION.

Q: Can MEREX 1000MG INJECTION be used by the elderly?

A: MEREX 1000MG INJECTION is recommended to be administered with caution and in a lower dosage to elders due to diminished function of the liver and kidneys and reduced folate levels in the blood. Consult the doctor before receiving MEREX 1000MG INJECTION.

Q: Is there any specific food to avoid while receiving MEREX 1000MG INJECTION?

A: It is recommended to avoid the consumption of drinks containing caffeine, such as black tea, coffee, and soft drinks, along with MEREX 1000MG INJECTION, to manage dehydration.

2. Hao, F., Lee, R.J., Yang, C., Zhong, L., Sun, Y., Dong, S., Cheng, Z., Teng, L., Meng, Q., Lu, J. and Xie, J., 2019. Targeted Co-delivery of siRNA and methotrexate for tumor therapy via mixed micelles. Pharmaceutics. [Published on 21st February 2019] [Accessed on 5th February 2024] https://www.mdpi.com/1999-4923/11/2/92

3. Sandoz Pty Ltd. [Revised in July 2022] [Accessed on 5th February 2024] https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent=&id=CP-2012-CMI-01899-3&d=20221026172310101

4. Sandoz Pty Ltd. [Revised on 8th July 2022]  [Accessed on 5th February 2024] https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent=&id=CP-2011-PI-03245-3&d=20221020172310101

5. Taj Pharmaceuticals Limited. [Revised on N.A] [Accessed on 5th February 2024] https://tajpharma.in/portfolio-item/methotrexate-injection-ip-1000mg-10ml-imutaj-taj-pharma/

6. Methotrexate. Aetos Pharma. [Accessed on 5th February 2024] https://www.aetospharma.com/product/methotrexate-injection-usp-250mg-10-ml/