INTRODUCTION

MELGAIN contains Decapeptide which is used to manage vitiligo. It helps to restore the color to dipigmented or white areas of skin. Vitiligo is a skin disorder characterized by hyperpigmentation (excessive lightening or whitening of the skin) with uneven white patches appear on the skin leaving a clearly noticeable uneven colour. This is due to the malfunctioning of the cells in the epidermis of the skin that are responsible for producing melanin (melanocytes).

This medicine works by causing migration of melanin producing cells from the area of skin surrounding the vitiligo patch. This causes the production of melanin and thus restores the skin colour. This medicine is for external use only. MELGAIN can make your skin more sensitive to sun, hence use sunscreen lotions and protective clothing while going in sun. The common side effects are dry skin, skin irritation or burning sensation. Before using this medicine, tell your doctor if you have any medical conditions, pregnant or breastfeeding.

USES OF MELGAIN

• Manage vitiligo

HOW MELGAIN WORKS

MELGAIN works by causing migration of melanin producing cells from the area of skin surrounding the vitiligo patch. This causes the production of melanin and thus restores the skin colour.

DIRECTIONS FOR USE

MELGAIN is for external use only. Use this medicine advised by your doctor. Shake it well and apply evenly to the affected area.

SIDE EFFECTS OF MELGAIN

HOW TO MANAGE SIDE EFFECTS

Dry skin:

Use moisturizers to provide a seal over your skin to avoid water from escaping. Avoid harsh, drying soaps and apply moisturizers immediately after bath.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are using or have recently taken any other topical medicines, including medicines obtained without a prescription.

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT MELGAIN

How do you use a MELGAIN?

Clean and dry the affected area thoroughly and then apply the lotion as a very thin film. For best results, apply it about 2 hours at night.

How does MELGAIN work?

It works by causing migration of melanin producing cells from the area of skin surrounding the vitiligo patch. This causes the production of melanin and thus restores the skin colour.

How long do I need to use MELGAIN?

The duration of management depends on the response to management. Normally, re-pigmentation can be seen on the borders or inside the white patch (as dots of pigment) in 3 to 6 months depending on the age of the white patch.

REFERENCES

1. Fox LP, Merk HF, Bickers DR. Dermatological Pharmacology. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page 1679-1706.

2. Serena Gianfaldoni, Georgi Tchernev, Uwe Wollina, Jacopo Lotti, Miriam Rovesti, Francesca Satolli, Katlein França and Torello Lotti. Vitiligo in Children: What’s New in Management? Jan 21, 2018; [Accessed on Dec 3, 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816304/

3. Prashiela Manga, Nada Elbuluk and Seth J. Orlow. Recent advances in understanding vitiligo: Sep 6, 2016; [Accessed on Dec 3, 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017284/

4. United pharmacies; https://www.unitedpharmacies.md/Melgain-Lotion-Decapeptide-Basic-Fibroblast-Growth-Factor.html [Accessed on Dec 3, 2020]