Introduction About MAXILIV INJECTION

MAXILIV INJECTION contains Glutathione which belongs to the group of medicines called Antioxidants. It is used to manage alcoholic fatty liver (disease that occurs due to heavy alcohol use), liver fibrosis/cirrhosis (scarring of liver due to excessive consumption of alcohol), and hepatitis (inflammation of liver) in affected individuals.

MAXILIV INJECTION is not recommended for use in patients allergic to Glutathione. Before receiving MAXILIV INJECTION, inform your doctor if you suffer from liver problems (such as chronic hepatitis), and kidney problems (such as acute renal failure).

MAXILIV INJECTION is not recommended for use in pregnant and breastfeeding women unless it is clearly necessary. It should be used with caution in neonates, premature infants, children, and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 70 years and above) after consulting the doctor.

The most common side effects of receiving MAXILIV INJECTION are anorexia (eating disorder), nausea, vomiting, and/or rash. Consult your doctor if any of these symptoms worsens.

Uses Of MAXILIV INJECTION

Manage:

• Alcoholic fatty liver (disease that occurs due to heavy alcohol use)
• Liver fibrosis/cirrhosis (scarring of liver tissue due to excessive consumption of alcohol)
• Hepatitis (inflammation of liver) in affected individuals

How MAXILIV INJECTION Works

MAXILIV INJECTION is an antioxidant which works by directly quenching reactive hydroxyl free radicals or other free radicals which manages damage to the liver cells thus managing alcoholic liver disease in affected individuals.

How to use MAXILIV INJECTION

MAXILIV INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion or into the muscle as an intramuscular injection. Your doctor will decide the correct dose and duration of management depending upon your age, body weight and disease condition.

Side Effects Of MAXILIV INJECTION

How To Manage Side Effects

Nausea And Vomiting

Receive MAXILIV INJECTION with/just after a meal. Stick to simple meals. Avoid eating oil rich/spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, and drink slowly in between meals. Consult your doctor if the condition worsens.

Warning & Precautions

Pregnancy

Monitoring required

MAXILIV INJECTION is not recommended for use in pregnant women unless it is clearly necessary. Consult your doctor before receiving the medicine.  

Breastfeeding

Monitoring required

MAXILIV INJECTION is not recommended for use in breastfeeding women unless it is clearly necessary. Consult your doctor before receiving the medicine.  

Kidney

Use with Caution

MAXILIV INJECTION should be used with caution in patients with kidney problems such as acute renal failure. Consult your doctor before receiving the medicine.

Liver

Use with Caution

MAXILIV INJECTION should be used with caution in patients with liver problems such as chronic hepatitis B. Consult your doctor before receiving the medicine.

Allergy

Contraindicated

Do not receive MAXILIV INJECTION if you are allergic to Glutathione, and/or any other ingredients of this medicine.

Interactions

A. Drug-Drug interactions:

Before receiving MAXILIV INJECTION, inform your doctor if you are taking any of the following medicine:

• vitamin K (used for blood clot and healing wounds)
• vitamin B12 (used to form red blood cells)
• calcium pantothenate (used to increase hair growth)
• antihistamines (medicines used for management of allergic reactions) Ex. cetirizine, chlorpheniramine.

Overdosage:

MAXILIV INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse immediately if you experience any unusual symptoms.

Synopsis

More Information

• Keep MAXILIV INJECTION out of reach of children.
• Do not store MAXILIV INJECTION below 25°C

FAQs About MAXILIV INJECTION

Q. What is MAXILIV INJECTION used for?

A. MAXILIV INJECTION is used to manage alcoholic fatty liver (disease that occurs due to heavy alcohol use), liver fibrosis/cirrhosis (scarring of liver due to excessive consumption of alcohol), and hepatitis (inflammation of liver) in affected individuals.

Q. What happens if MAXILIV INJECTION is administered more than its required dosage?

A. MAXILIV INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse immediately if you experience any unusual symptoms.

Q. What are the side effects of MAXILIV INJECTION?

A. The most common side effects of receiving MAXILIV INJECTION are anorexia (eating disorder), nausea, vomiting, and/or rash. Consult your doctor if any of these symptoms worsens.

Q. How MAXILIV INJECTION works?

A. MAXILIV INJECTION is an antioxidant which works by directly quenching reactive hydroxyl free radicals or other free radicals which manages damage to the liver cells thus managing alcoholic liver disease in affected individuals.

Q. How MAXILIV INJECTION is administered?

A. MAXILIV INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion or into the muscle as an intramuscular injection. Your doctor will decide the correct dose and duration of management depending upon your age, body weight and disease condition.

References

1. Murray M.Fisher. Ethanol metabolites in hepatic lipid peroxidation. Alcohol and Liver. Edition: November 2013. Page – 53.

2. Yasushi Honda, Takaomi Kessoku, Yoshio Sumida, Takashi Kobayashi, Takayuki Kato, Yuji Ogawa, Wataru Tomeno, Kento Imajo, Koji Fujita, Masato Yoneda, Koshi Kataoka, Masataka Taguri, Takeharu Yamanaka, Yuya Seko, Saiyu Tanaka, Satoru Saito, Masafumi Ono, Satoshi Oeda, Yuichiro Eguchi, Wataru Aoi, Kenji Sato, Yoshito Itoh, Atsushi Nakajima. Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. August 2017. [Accessed on 14th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549431/

3. Li Qian, Wenjun Wang, Yan Zhou, Jianxin Ma. Effects of reduced glutathione therapy on chronic hepatitis B. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. May 2017. [Accessed on 14th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470607/

4. Zuventus Healthcare Ltd. Maxiliv Injection. [Accessed on 14th November 2022] http://www.zuventus.co.in/doctor_wise_products_selected.aspx?Medi_Id=357

5. C Costagliola, L Romano, G Scibelli, A de Vincentiis, P Sorice, A Di Benedetto. Anemia and chronic renal failure: a therapeutical approach by reduced glutathione parenteral administration. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. 1992. [Accessed on 14th November 2022] https://pubmed.ncbi.nlm.nih.gov/1501736/

Useful Diagnostic Tests

• Blood test

Author Details

Written By Dr. K .AZEEM HUSSAIN - B.D.S

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 30 Jan 2023 | 05:51 PM(IST)