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Introduction About LUPIFOS POWDER
LUPIFOS POWDER contains Fosfomycin, which belongs to the group of medicines called Antibiotics. It is used to manage or manage uncomplicated infections of the bladder in women and female adolescents. It is also used as an antibiotic prophylaxis for transrectal prostate biopsy in men.
LUPIFOS POWDER should not be used in patients who have severe kidney problems or are on haemodialysis. It should be used cautiously in patients who have persistent infections of the bladder and who have experienced symptoms of diarrhoea after taking any other antibiotics.
LUPIFOS POWDER is not recommended for use in pregnant women unless considered necessary and is not recommended for use in breastfeeding women as it may pass through the breast milk. LUPIFOS POWDER is generally not recommended for use in children (under 12 years of age) and should be used with caution in elderly patients. The most common side effects are headaches, dizziness, diarrhoea, nausea and indigestion. If any of these symptoms worsen, contact your doctor.
Uses Of LUPIFOS POWDER
- Manage or manages uncomplicated infection of the bladder in women and female adolescents
- Prophylactic management of transrectal prostate biopsy in adult man
How LUPIFOS POWDER Works
LUPIFOS POWDER works by killing bacteria through the inactivation of an enzyme involved in bacterial cell wall synthesis and reduces adherence of the bacteria to the cells lining the urinary tract. This kind of action helps to manage uncomplicated urinary tract infections and manage infections after prostate biopsy.
How to use LUPIFOS POWDER
Take LUPIFOS POWDER as advised by your physician. Check the label for directions before use. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
Side Effects Of LUPIFOS POWDER
Common
- headache
- dizziness
- diarrhoea
- nausea
- indigestion
- abdominal pain
- inflammation, irritation and itching due to infection of the female genital organs
Uncommon
- vomiting
- rash
- urticaria
- itching
- tingling or numbness
- rash
- tiredness
Rare
Stop taking LUPIFOS POWDER and contact your doctor immediately if you experience any of the following side effects:
- anaphylactic shock symptoms such as the sudden onset of rash, itching or hives on the skin and or shortness of breath, wheezing or trouble breathing
- serious allergic reaction symptoms such as swelling of the face, lips, tongue or throat with breathing difficulties (angioedema)
- faster heartbeat (tachycardia)
- large intestine (pseudomembranous colitis) infection symptoms such as severe abdominal cramps, bloody stools and /or fever
- severe diarrhoea
How To Manage Side Effects
Dizziness:
Sit down or lie down slowly when you are feeling dizzy. Take some time to rest and drink plenty of water. Avoid coffee and other carbonated drinks. If there is no improvement in the symptom, contact your doctor.
Headache:
Try to rest and relax. Apply pain balm to the head to ease the pain. Sip on some hot water or ginger tea. If your symptoms do not improve, contact your doctor immediately.
Nausea:
Take LUPIFOS POWDER with or just after, meals. Stick to simple meals and avoid eating foods rich in oil or spicy foods. If your symptoms do not improve, contact your doctor immediately.
Indigestion:
Take your meal at the right time, drink lots of water and go for a walk after each meal. If the symptom does not improve, contact your doctor immediately.
Diarrhoea:
Increase your intake of fluids, such as water or fruit juice, to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor immediately.
Stomach pain:
Take a rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Place a heating pad on your stomach. If the symptom does not improve, contact your doctor immediately.
Warning & Precautions
Pregnancy
LUPIFOS POWDER is not recommended for use by pregnant women unless recommended by your doctor. Consult your doctor before taking it.
Breastfeeding
LUPIFOS POWDER should not be used by breastfeeding women because it may pass through the breast milk. Consult your doctor before taking it.
Driving and Using Machines
Do not drive or operate any machines if you feel dizzy or fatigued after taking LUPIFOS POWDER.
Kidney
LUPIFOS POWDER is not recommended for use in patients with severe kidney problems, undergoing haemodialysis (a procedure used to clean the blood by removing waste and extra fluids when the kidneys are not functioning), etc. It should be used with caution in patients with other kidney problems. Consult your doctor before taking it.
Liver
LUPIFOS POWDER should be taken with caution in patients with liver disease. Consult your doctor before taking it.
Allergy
Do not take LUPIFOS POWDER if you are allergic to Fosfomycin or any of the other ingredients of this medicine.
Others
Before taking LUPIFOS POWDER, inform your doctor if you:
- have persistent infections of the bladder
- have experienced the symptoms of diarrhoea after taking any other antibiotics
- have an intolerance to some sugars
Use in Pediatrics:
LUPIFOS POWDER is generally not recommended for use in children (under 12 years of age). Consult your doctor before taking LUPIFOS POWDER.
Use in Geriatrics:
LUPIFOS POWDER should be used with caution in elderly patients. Consult your doctor before taking LUPIFOS POWDER.
Interactions
A. Drug-Drug interactions:
Before taking LUPIFOS POWDER, inform your doctor if you are taking any of the following medicine:
- metoclopramide (medicine that increases the movement of food through the stomach and intestines)
- anticoagulants (used to manage blood clots)
- cimetidine (used to manage ulcers)
Overdosage:
If you or anyone else accidentally take too much of LUPIFOS POWDER, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are vestibular loss, impaired hearing, metallic taste and a general decline in taste perception.
Synopsis
| Drug | : | Fosfomycin |
| Pharmacological Category | : | Antibiotics |
| Therapeutic Indication | : | Uncomplicated infection of the bladder in women and female adolescents, prophylactic management of transrectal prostate biopsy in men |
| Dosage Forms | : | Tablet |
More Information
- Keep LUPIFOS POWDER out of reach of children
- Store at room temperature
FAQs About LUPIFOS POWDER
Can LUPIFOS POWDER cause diarrhoea?
Yes, LUPIFOS POWDER may cause diarrhoea in some individuals. Increase your intake of fluids, such as water or fruit juice, to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
How long does LUPIFOS POWDER take to act?
After taking LUPIFOS POWDER exactly as instructed by your doctor, your symptoms should improve in 2–3 days. If the symptoms do not improve, contact your doctor immediately.
Can we use LUPIFOS POWDER for people with kidney problems?
LUPIFOS POWDER is not recommended for use in patients with severe kidney problems, those undergoing haemodialysis management (a procedure used to clean the blood by removing waste and extra fluids when the kidneys are not functioning), etc. It should be used with caution in patients with other kidney problems. Consult your doctor before taking it.
What should I do if I forget to take LUPIFOS POWDER?
Take the missed dose of LUPIFOS POWDER as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Can I take LUPIFOS POWDER during pregnancy?
No, LUPIFOS POWDER should not be used in pregnant women unless prescribed by a doctor. Consult your doctor before taking it.
References
1. KD Tripathi. Antimicrobial Drugs. Essentials of medical pharmacology. 8th editions. 2019. Page – 731.
2. George G. Zhanel, Andrew J. Walkty, and James A. Karlowsky. Fosfomycin: A First-Line Oral Therapy for Acute Uncomplicated Cystitis, NIH National Library of Medicine, National Center for Biotechnology Information. PMC, PubMed Central. May 2016. [Accessed on 13th June 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904571/
3. Lynn L. Silver. Fosfomycin: Mechanism and Resistance. NIH National Library of Medicine, National Center for Biotechnology Information. PMC, PubMed Central. February 2017. [Accessed on 13th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287057/
4. Zambon. Fosfomycin. [Accessed on 13th June 2022] https://biosupply.fffenterprises.com/fosfomycin-tromethamine-3gm.html
5. Special Product’s Line S.p.A. Electronic Medicines Compendium (EMC). [Revised in November 2017] [Accessed on 13th June 2022] https://www.medicines.org.uk/emc/files/pil.7219.pdf
6. Zambon S.p.A. Health Products Regulatory Authority (HPRA). [Revised in June 2020] [Accessed on 13th June 2022] http://www.hpra.ie/img/uploaded/swedocuments/075c78a7-31e0-4d29-8dcb-901d014d64b1.pdf
7. Ciplamed. Fosirol. [Revised in May 2016] [Accessed on 13th June 2022] https://www.ciplamed.com/content/fosirol-powder
Useful Diagnostic Tests
- Complete Blood Count
- Urine Routine & Microscopy
Author Details
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
