Introduction About LOBG 0.5MG TABLET

LOBG 0.5MG TABLET contains Lobeglitazone which belongs to the group of medicines called Antidiabetic agents. It is used to manage type 2 diabetes mellitus patients who are inadequately controlled by diet and exercise and for whom where other anti-diabetic is inappropriate. Diabetes mellitus is a chronic, metabolic disease characterized by elevated levels of blood glucose (or blood sugar), which leads over time to serious damage to the heart, blood vessels, eyes, kidneys, and nerves.

Lobeglitazone acts as an insulin sensitizer by binding and activating peroxisome proliferator-activated receptors (PPAR) gamma within fat cells. Also, by promoting the binding of insulin at fat cells, LOBG 0.5MG TABLET has been shown to reduce blood sugar levels, lower hemoglobin A1C (HbA1C) levels, and improve lipid and liver profiles.

LOBG 0.5MG TABLET is not recommended for patients with liver impairment. Dosage adjustment is not necessary for renal impairment patients. The common side effects of taking this medicine are edema and weight gain. Consult your doctor if any of the above side persists for a longer duration.

Uses Of LOBG 0.5MG TABLET

• Used to manage type 2 diabetes mellitus patients

How LOBG 0.5MG TABLET Works

LOBG 0.5MG TABLET acts as an insulin sensitizer by binding and activating peroxisome proliferator-activated receptors (PPAR) gamma within fat cells. Also, by promoting the binding of insulin at fat cells, LOBG 0.5MG TABLET has been shown to reduce blood sugar levels, lower hemoglobin A1C (HbA1C) levels, and improve lipid and liver profiles.

How to use LOBG 0.5MG TABLET

Take LOBG 0.5MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration depending upon your age, body weight and disease condition.

Side Effects Of LOBG 0.5MG TABLET

Warning & Precautions

Pregnancy

Consult your doctor

There is limited information available regarding pregnant women. Hence, consult your doctor before taking LOBG 0.5MG TABLET.

Breastfeeding

Consult your doctor

There is limited information available regarding breastfeeding women. Hence, consult your doctor before taking LOBG 0.5MG TABLET.

Kidney

Use with Caution

LOBG 0.5MG TABLET should be used with caution in patients with kidney impairment. Dosage adjustment is not necessary for patients with mild to moderate renal impairment. Consult your doctor before taking the medicine.

Liver

Contraindicated

LOBG 0.5MG TABLET is not recommended for use in patients with acute liver diseases or increased serum transaminase levels. Consult your doctor before taking the medicine.

Allergy

Contraindicated

Do not take LOBG 0.5MG TABLET if you are allergic or hypersensitive to Lobeglitazone or any other ingredients of this medicine.

Interactions

A. Drug-Drug interactions:

Before taking LOBG 0.5MG TABLET, inform your doctor if you are taking any prescription, non-prescription and herbal supplements.

Overdosage:

If you or anyone else accidentally took more LOBG 0.5MG TABLET consult your doctor immediately or nearby hospital.

Synopsis

More Information

• Keep LOBG 0.5MG TABLET out of reach of children
• Store LOBG 0.5MG TABLET at room temperature

FAQs About LOBG 0.5MG TABLET

Q: What is LOBG 0.5MG TABLET used for?

A: It is used to manage type 2 diabetes mellitus patients who are inadequately controlled by diet and exercise and for whom where other anti-diabetic is inappropriate.

Q: How and when to take LOBG 0.5MG TABLET?

A: Take LOBG 0.5MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration depending upon your age, body weight and disease condition.

Q: What to do if I forgot to take a dose of LOBG 0.5MG TABLET?

A: If you forgot to take a dose of LOBG 0.5MG TABLET, take it as soon as you remember. However, if it is time for the next dose of LOBG 0.5MG TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of LOBG 0.5MG TABLET to compensate the missed ones.

Q: Can I stop taking LOBG 0.5MG TABLET without consulting the doctor?

A: No. You should not stop taking LOBG 0.5MG TABLET without consulting the doctor because it may cause some side effects.

Q: Will taking a higher dose of LOBG 0.5MG TABLET be more effective?

A: No, taking a higher dose of LOBG 0.5MG TABLET will not be effective. Always stick to the dose and duration prescribed by your doctor.

Q: What precautions do I need to follow while taking LOBG 0.5MG TABLET?

A: LOBG 0.5MG TABLET is not recommended for patients with liver impairment. Dosage adjustment is not necessary for renal impairment patients.

Q: How much LOBG 0.5MG TABLET should I take?

A: LOBG 0.5MG TABLET should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.

References

1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 270.

2. Joonsang Yoo, Jimin Jeon, Minyoul Baik, and Jinkwon Kim. Lobeglitazone, a novel thiazolidinedione, for secondary prevention in patients with ischemic stroke: a nationwide nested case-control study. National Library of Sceience. May 05, 2023 [Accessed on December 28th, 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163714/

3. Pubchem. [Accessed on December 28th, 2023] https://pubchem.ncbi.nlm.nih.gov/compound/Lobeglitazone

4. Drugbank.com. [Accessed on December 28th, 2023] https://go.drugbank.com/drugs/DB09198

5. WHO. Diabetes. [Accessed on December 28th, 2023] https://www.who.int/health-topics/diabetes#tab=tab_1

6. Larenon.com. [Accessed on December 28th, 2023] https://www.larenon.com/wp-content/uploads/2023/03/LOBULA-0.5-LBL.pdf

7. Jaehyun Bae, Taegyun Park, Hyeyoung Kim, Minyoung Lee, and Bong-Soo. Lobeglitazone: A Novel Thiazolidinedione for the Management of Type 2 Diabetes Mellitus. April 19, 2021 [Accessed on December 28th, 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164939/

Useful Diagnostic Tests

• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
• Blood Glucose Fasting (FBS)
• Post Prandial Blood Sugar (PPBS)
• Insulin - Fasting
• Netmeds Diabetic Checkup
• Advance Diabetes Monitoring (Senior Female)
• Jaanch Diabetic Profile Basic