Introduction About KOLQ SYRUP

KOLQ SYRUP is a combination of Chlorpheniramine, Menthol, Paracetamol, Phenylephrine and Sodium Citrate which belongs to the group of medicines called Antihistamines, Cooling agents, Analgesics & Antipyretics, Nasal decongestant and Mucolytics respectively. It is used to relieve nasal and sinus congestion, allergic symptoms of the nose or throat due to hay fever, upper respiratory tract allergies (symptoms include runny nose, cough, sneezing, watery eyes, sore throat, body ache, and fever), sinus pain and headache. It is also used in combination with antibacterial in sinusitis, tonsillitis and otitis media.

KOLQ SYRUP is not recommended for use in patients with liver dysfunction, severe kidney disease, severe high blood pressure and glaucoma. Contact your doctor before taking. KOLQ SYRUP should be used with caution in patients with asthma, COPD, bronchiectasis, diabetes mellitus, fits and hyperthyroidism. Contact your doctor before taking. KOLQ SYRUP is not recommended for use in pregnancy unless considered clearly necessary. Contact your doctor before taking.

KOLQ SYRUP is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking. KOLQ SYRUP should be used with caution in children under 2 years of age. Contact your doctor before taking. KOLQ SYRUP should be used with caution in elderly patients aged above 65 years. Contact your doctor before taking. The most common side effects of taking KOLQ SYRUP are nausea, vomiting, diarrhea, rash, headache, dizziness and sedation. Contact your physician if any of the above side effects worsen.

Uses Of KOLQ SYRUP

It is used to relieve:

• nasal and sinus congestion
• allergic symptoms of the nose or throat due to hay fever, upper respiratory tract allergies
• sinus pain and headache

How KOLQ SYRUP Works

KOLQ SYRUP helps to relief cold and flu where Chlorpheniramine blocks the binding of histamine (responsible for allergic reactions such as sneezing, watery and itchy eyes, and runny nose) to Histamine H1receptors, thus managing allergic reactions. Menthol helps to give the sensation of breathing easier and reduces cough by acting on the cold receptors present in the nose and throat. Paracetamol belongs to Analgesics and Antipyretics works to stop the pain messengers from getting through to the brain and also acts in the brain to reduce fever. Thus, decreasing pain and fever. Phenylephrine works by reducing congestion in the upper respiratory tract, including the nose, nasal passages and sinuses, and making it easier to breathe. Sodium Citrate belongs to Mucolytics, thins and loosen phlegm in the nose, trachea and lungs helps to make coughing easier.

How to use KOLQ SYRUP

Take KOLQ SYRUP as advised by your physician. Shake well before use. Your physician will decide the correct dose and duration depending upon age, body weight and disease condition.

Side Effects Of KOLQ SYRUP

How To Manage Side Effects

Diarrhea

Drink plenty of water or fruit juices to keep you hydrated. Do not take any medicine on your own for managing diarrhoea. Contact your doctor if diarrhoea did not improve.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not consume alcohol, as it increases dizziness. Contact your doctor if dizziness did not improve.

Headache

Rest and relax. Drink plenty of fluids such as water or electrolytes and apply a pain-relieving balm on the head if required. Do not consume alcohol. Contact your doctor if headache worsens.

Nausea And Vomiting

Take this medicine with, or just after food. Eat simple meals and avoid oily or spicy foods. Contact your doctor if nausea and vomiting did not improve.

Skin rash Or Itching

Avoid hot water bath as it irritates the skin and do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if rashes worsen.

Warning & Precautions

Pregnancy

Monitoring required

KOLQ SYRUP is not recommended for use in pregnancy unless considered clearly necessary. Contact your doctor before taking.

Breastfeeding

Contraindicated

KOLQ SYRUP is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines after taking KOLQ SYRUP. Consult your doctor for advice.

Alcohol

Contraindicated

Alcohol consumption is not recommended while taking KOLQ SYRUP as it may lead to unwanted effects.

Kidney

Contraindicated

KOLQ SYRUP is not recommended for use in patients with severe kidney disease. Contact your doctor before taking.

Liver

Contraindicated

KOLQ SYRUP is not recommended for use in patients with liver dysfunction. Contact your doctor before taking.

Allergy

Contraindicated

Do not take KOLQ SYRUP if you are allergic to Chlorpheniramine, Menthol, Paracetamol, Phenylephrine and Sodium Citrate, or to any other ingredients of the medicine.

Lungs

Use with Caution

KOLQ SYRUP should be used with caution in patients with lung diseases such as asthma, COPD, bronchiectasis. Contact your doctor before taking.

Heart Disease

Consult your doctor

KOLQ SYRUP is not recommended for use in severe high blood pressure. It should be used with caution in cardiovascular diseases such as myocardial disease, bradycardia, partial heart block or severe arteriosclerosis. Contact your doctor before taking.

Use In Pediatrics

Use with Caution

KOLQ SYRUP should be used with caution in children under 2 years of age. Contact your doctor before taking KOLQ SYRUP.

Use In Geriatrics

Use with Caution

KOLQ SYRUP should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking KOLQ SYRUP.

Interactions

A. Drug-Drug interactions:

Before taking KOLQ SYRUP, inform your doctor if you are taking any of the following medicine:

• amitriptyline (medicines used to manage depression)
• salbutamol, ephedrine (medicines used to manage asthma)
• propranolol (medicines used to manage high blood pressure, heart diseases)
• methyldopa, reserpine, veratrum alkaloids (medicines used to manage high blood pressure)
• digoxin (medicines used for heart failure)
• warfarin (medicines used to manage blood clots)
• metoclopramide (medicines used to manage nausea and vomiting)
• antidepressants with anticholinergic properties
• oxycodone, tramadol (medicines used to manage severe pain)  
• chloramphenicol (medicines used for bacterial infections)
• phenytoin (medicines used to manage fits/seizures)
• probenecid (medicines used to manage gout)
• cholestyramine (medicines used to manage high blood cholesterol levels)
• zidovudine (medicines used to manage HIV infections)
• hypnotics or anxiolytics (Ex. diazepam, lorazepam)

Overdosage:

If you or anyone else accidentally took too much of KOLQ SYRUP, consult your doctor immediately or visit the nearby hospital.

Synopsis

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References

1. K.D. Tripathi. Respiratory System Drugs, Drugs Acting on Skin and Mucous Membranes, NSAIDs and Antipyretic-Analgesics, Drugs acting on ANS. Essentials of medical pharmacology. Seventh edition. 2013. Page-220, 888, 207, 135.

2. Centaur Pharma. Sinarest Syrup. (Chlorpheniramine maleate, Menthol, Paracetamol, Phenylephrine and Sodium Citrate). [Revised in January 2022] [Accessed on 18th July 2022] https://www.centaurpharma.com/downloads/2021/pediatrics/cold/Sinarest%20syrup.pdf

3. Centaur Pharma. Sinarest Plus Suspension. (Chlorpheniramine maleate, Menthol, Paracetamol, Phenylephrine and Sodium Citrate). [Revised in January 2022] [Accessed on 18th July 2022] https://www.centaurpharma.com/downloads/2022/pediatrics/cold/Sinarest%20Plus%20suspension.pdf

4. Dr. D Pharma. Dcoldee Suspension. (Chlorpheniramine maleate, Menthol, Paracetamol, Phenylephrine and Sodium Citrate). [Accessed on 18th July 2022] https://www.drdpharma.in/product/phenylepherine-2-5-mg-chlorpheniramine-2mg-paracetamol-125-mg-susp