KEZRIN Cream 15gm
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Introduction About KEZRIN CREAM
KEZRIN CREAM is used to manage fungal skin infections. It can be applied on your hands, feet, genital area, trunk, scalp, face and chest.
It contains an antifungal agent called Ketoconazole which works by stopping the growth of fungi. Use KEZRIN CREAM as advised by your physician. Apply the required amount of the medicine to the affected skin areas.
Before applying KEZRIN CREAM, inform your doctor if you are using a cream, ointment or lotion that contains a steroid.
KEZRIN CREAM can be used if you are pregnant or breast-feeding, however, consult your doctor for advice. KEZRIN CREAM is not recommended for use in children and adolescents (under 18 years of age).
The most common side effects of applying KEZRIN CREAM are burning sensation, skin redness, or itching. If any of the symptoms worsen, contact your doctor.
Uses Of KEZRIN CREAM
- Management of fungal skin infections
How KEZRIN CREAM Works
KEZRIN CREAM contains Ketoconazole which works by stopping the growth of fungi. It blocks the production of a substance called ergosterol, which is essential for the fungi's cell membrane. Without ergosterol, the cell membrane becomes weak, causing the fungi to die and the infection to clear up.
How to use KEZRIN CREAM
Apply KEZRIN CREAM as advised by your physician. It is for external use only. Wash the infected area and dry it well. Apply it to the affected and immediate surrounding area with clean fingers. Unless the affected skin is on your hands, wash your hands with soap and water after using KEZRIN CREAM in order to stop you from spreading the infection to other parts of your body or to other people.
Keep using KEZRIN CREAM until a few days after all symptoms have completely disappeared. This is to manage your symptoms from recurring.
Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Usually, you will see improvement after 4 weeks but if you don’t, talk to your doctor.
Side Effects Of KEZRIN CREAM
Common
- burning sensation
- skin redness or itching
Uncommon
- hypersensitivity
- raised blisters or inflammation of the skin
- shedding of the skin
- problems where the medicine is applied (bleeding, discomfort, dryness, inflammation, tingling)
- skin irritation like rash
- sticky skin
Stop applying KEZRIN CREAM and contact your doctor immediately if you experience any of the following side effects:
- severe irritation or reddening of the skin where the medicine has been applied, or other signs of allergy during initial management days
- peeling or blistering of the skin
How To Manage Side Effects
Skin rash Or Itching
Applying a cold compress, damp cloth, or cool showers can bring immediate relief to swelling and reduce itching. Avoid hot showers because hot water can further irritate your skin. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash persists.
Warning & Precautions
Pregnancy
Consult your doctorKEZRIN CREAM can be used if you are pregnant, however, consult your doctor for advice.
Breastfeeding
Consult your doctorKEZRIN CREAM can be used if you are breast-feeding, however, consult your doctor for advice.
Driving and Using Machines
Use with CautionKEZRIN CREAM is unlikely to affect your ability to drive or to use machinery.
Allergy
ContraindicatedDo not apply KEZRIN CREAM if you are allergic to Ketoconazole or any of the other ingredients of this medicine.
Use In Pediatrics
ContraindicatedKEZRIN CREAM is not recommended for use in children and adolescents (under 18 years of age). Consult your child’s doctor for advice.
Others
KEZRIN CREAM is not recommended for eye infections. Consult your doctor for advice.
Interactions
A. Drug-Drug interactions:
Before applying KEZRIN CREAM, inform your doctor if you are using the following medicines:
- medicines used to manage inflammatory conditions (Ex. betamethasone, hydrocortisone)
Overdosage:
If you or anyone else accidentally apply too much of KEZRIN CREAM, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include burning sensation, redness or swelling.
Synopsis
| Drug | : | Ketoconazole |
| Pharmacological Category | : | Azole antifungal |
| Therapeutic Indication | : | Fungal infections |
| Dosage Forms | : | Tablet, Solution, Scalp Solution, Cream, Gel, Lotion, Ointment, Shampoo, Soap, Body Wash, Bar, Eye Drops, Dusting Powder, Scrub |
More Information
Storage
- Keep KEZRIN CREAM out of reach of children
- Do not store above 25°C
FAQs About KEZRIN CREAM
Q: What does KEZRIN CREAM contain?
A: KEZRIN CREAM contains Ketoconazole which belongs to the group of medicines called Antifungals.
Q: What is KEZRIN CREAM used for?
A: It is used in adults to manage fungal skin infections which may appear on the skin of the hands, feet, genital area, trunk, groin, scalp, face, chest or back.
Q: How does KEZRIN CREAM work?
A: KEZRIN CREAM reduces fungal infection by inhibiting the growth of the fungus by weakening the structure and function of the fungal cell membrane.
Q: How often should I apply KEZRIN CREAM?
A: Your doctor will decide the correct dose and duration of KEZRIN CREAM for you depending upon your age, body weight and disease condition. Depending on the infection type, management may last 2 to 6 weeks. Do not apply it for more duration than advised by your doctor.
Q: What if I swallow KEZRIN CREAM?
A: Accidental swallowing of small quantities of KEZRIN CREAM is usually harmless but, consult your doctor immediately if you or anyone else swallow it. Take the medicine with you for the doctor to know what you have ingested.
Q: How do I apply KEZRIN CREAM?
A: Apply KEZRIN CREAM as directed by your physician. Wash the infected area and dry it properly. Keep a towel and a flannel for your personal use to manage infecting anyone else. Apply the medicine gently into the affected area and surrounding skin with clean fingers. Clothing which touches the infected areas should be washed and changed frequently. Consult your doctor if you have any doubts regarding its use.
Q: What if I forget to apply KEZRIN CREAM?
A: If you forget to apply KEZRIN CREAM, use as per the directions next time you apply it. Do not use the medicine two times to make up for the missed dose.
Q: Can I stop applying KEZRIN CREAM?
A: Do not stop applying KEZRIN CREAM without asking your doctor. You will usually see signs of improvement after 4 weeks. If not, talk to your doctor. Continue using the medicine until a few days after all symptoms have completely disappeared. Even after your skin is completely cured, you sometimes have to apply the medicine once weekly or once per 2 weeks to manage your symptoms from coming back.
Q: Can I use other medicines with KEZRIN CREAM for my skin condition?
A: Before using KEZRIN CREAM, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, over the counter or any herbal medicine. If you have been regularly using a lotion or cream, containing a steroid (Ex. betamethasone or hydrocortisone) for your skin condition, you should wait for two weeks before starting management with KEZRIN CREAM. This will stop your condition flaring up while KEZRIN CREAM starts to work. If you have any queries about stopping your steroid lotion or cream, consult your doctor.
References
1. KD. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page-791, 792.
2. Hadeer Sinawe, Damian Casadesus. Ketoconazole. NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls [Internet]. June 2022. [Accessed 18th October 2024] https://www.ncbi.nlm.nih.gov/books/NBK559221/
3. Choi FD, Juhasz MLW, Atanaskova Mesinkovska N. Topical ketoconazole: a systematic review of current dermatological applications and future developments. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. October 1987. [Accessed on 18th October 2024] https://pubmed.ncbi.nlm.nih.gov/30668185/
4. Janssen Pharmaceutica NV. Health Products Regulatory Authority (HPRA). [Revised in July 2022] [Accessed on 18th October 2024] https://www.hpra.ie/img/uploaded/swedocuments/4bf3b755-f85e-41e5-916a-b7c9a7fc10d6.pdf
5. Janssen Pharmaceutica NV. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed 18th October 2024] https://www.medicines.org.uk/emc/files/pil.970.pdf
6. Palsons Derma. Novale scalp lotion (Ketoconazole 2%). [Accessed on 18th October 2024] https://www.palsonsderma.com/novale-scalp-lotion
7. Praise Pharma. Esava ointment. (Ketoconazole 2%). [Accessed on 18th October 2024] http://www.praisepharma.com/products/anti-fungal_esava-ointment.html
Useful Diagnostic Tests
- Skin care package
Author Details
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