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Introduction About KEMCURE DT TABLET
KEMCURE DT TABLET contains Ketorolac, which belongs to the group of medicines called Painkillers. It is used for short-term pain relief (5 or 7 days) of sudden moderate to severe pain associated with surgical procedures (such as general surgery, orthopaedic and dental surgery), Musculo-skeletal pain (such as severe joint pain, muscle pain), post-partum uterine cramping pain and other pain conditions when your doctor prescribes.
Take KEMCURE DT TABLET only under medical supervision. It can be taken with or without food. Take this medicine only for the duration as advised by your physician. Usually, it is not taken more than 7 days without doctor consultation.
KEMCURE DT TABLET is not recommended for use in patients taking other NSAIDs (Ex. aspirin) or those having advanced kidney, heart, cerebrovascular or gastrointestinal diseases or a tendency to bleed easily. Before taking KEMCURE DT TABLET, inform your doctor if you have liver, lung or heart diseases, high blood pressure or inflammatory bowel diseases.
KEMCURE DT TABLET is not recommended for use in pregnancy (especially during the last 3 months) and in breastfeeding mothers. KEMCURE DT TABLET is not recommended for use in children (below 17 years of age). KEMCURE DT TABLET should be used with caution in elderly patients above 65 years of age.
Avoid smoking and consumption of alcohol with KEMCURE DT TABLET. The most common side effects of taking KEMCURE DT TABLET include nausea, indigestion, stomach pain, diarrhoea, dizziness or drowsiness, headache or swelling. Consult your doctor immediately if the symptoms worsen or persist.
Uses Of KEMCURE DT TABLET
It is used for short-term pain relief (5 or 7 days) of sudden moderate to severe pain associated with:
- Surgical procedures (such as general surgery, orthopaedic and dental surgery)
- Musculo-skeletal pain (such as severe joint pain, muscle pain)
- Post-partum uterine cramping pain
- Other pain conditions when your doctor prescribes
How KEMCURE DT TABLET Works
KEMCURE DT TABLET contains Ketorolac which works by blocking enzymes called COX-1 and COX-2, which are involved in producing chemicals (prostaglandins) that cause pain and inflammation. By stopping these enzymes, ketorolac helps reduce pain, swelling, and inflammation in the body.
How to use KEMCURE DT TABLET
Take KEMCURE DT TABLET as advised by your physician. It can be taken with or without food.
For Tablet, Capsule: Swallow KEMCURE DT TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse KEMCURE DT TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution.
Your doctor will decide the correct dose and duration of KEMCURE DT TABLET therapy for you depending upon your age, body weight and disease condition. Continue to take KEMCURE DT TABLET for the stipulated duration prescribed by your doctor to achieve better results.
Side Effects Of KEMCURE DT TABLET
Common
- nausea, indigestion, stomach pain, diarrhea, constipation
- dizziness, drowsiness, headache
- swelling
- sleepiness or lack of sleep
- nervousness
- fever
Uncommon
- abnormal dreams, anxiety, dry mouth, hyperactivity, tingling and prickling sensation, increased sweating, euphoria, hallucinations
- loss of appetite, gas, vomiting, inflamed and sore mouth, gastritis, sore throat
- lack of energy, pain, back pain
- vasodilatation, throbbing sensation, high blood pressure
- migraine
- muscle or joint pain
- rash, hives
- discomfort, pain or burning while peeing
Rare
- worsening of inflammatory bowel disease like ulcerative colitis or Crohn’s disease, ulcerative stomatitis
- blood disorders like agranulocytosis, hemolytic anemia, aplastic anemia, lymphadenopathy, pancytopenia (due to changes in the number of blood cells)
- postoperative bleeding
- increased blood sugar levels
- high potassium levels (shortness of breath, chest pain, nausea, vomiting)
- low sodium levels (whole body dizziness, fatigue, lethargy, weakness, thirst)
- aseptic meningitis (brain and spinal cord membrane inflammation), psychosis, fits
- bronchospasm (tightness of chest), pneumonia, respiratory depression
- conjunctivitis (eye inflammation)
Stop taking KEMCURE DT TABLET and contact your doctor immediately if you experience any of the following side effects:
- shortness of breath
- swelling, rapid weight gain
- skin rash
- bleeding in stomach (bloody or tarry stools, coughing up blood or vomit that may look like coffee grounds)
- liver problems (nausea, stomach pain, itchiness, tiredness, flu-like symptoms, clay-coloured stools, dark urine, yellowing of the skin or eyes, loss of appetite)
- anaemia (paleness of skin, light-headedness, fast heart rate, difficulty in concentrating, shortness of breath)
- kidney problems (little or no urine production, difficulty or pain while urinating, swelling of legs, tiredness, shortness of breath)
- heart attack or stroke (chest pain spreading to jaw or shoulder, slurred speech, sudden numbness or weakness on one side of the body, feeling short of breath)
- allergic reaction (hives, difficulty in breathing, swelling of face or throat)
- severe skin reaction (fever, burning eyes, sore throat, skin pain, purple or red skin rash that spreads and causes blistering and peeling)
- flank pain with or without haematuria, haemolytic uraemic syndrome (damage or inflammation of small blood vessels in kidneys)
How To Manage Side Effects
Constipation
Eat plenty of fiber rich foods such as vegetables, fresh fruits and cereals and drink plenty of water. Exercise more regularly. If symptom persists, contact your doctor.
Diarrhea
Drink lots of fluids, such as water or fruit juice for hydration. Do not consume any medicine on your own without asking your doctor. If symptom persists, contact your doctor.
Dizziness Or Drowsiness
When you feel dizzy, lie or sit down immediately. Lie-down in a dark and quite place with eyes closed. Vehicle driving should be avoided if you experience frequent dizziness without warning. If symptom persists, contact your doctor.
Dry Mouth
Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. If symptom persists, contact your doctor.
Headache
Try to take rest in a quiet dark room. Don’t involve yourself in exertive activities. Apply a pain-relieving balm on your forehead. If symptom persists, contact your doctor.
Nausea And Vomiting
Drink ice cold drinks. Try to avoid sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Take KEMCURE DT TABLET with or just after meals. Stick to simple meals. Avoid eating rich or spicy food. If symptom persists, contact your doctor.
Stomach Pain
Try to rest and relax. Try to have smaller and frequent meals. Keep a heat pad on your stomach. If symptom persists, contact your doctor.
Warning & Precautions
Pregnancy
ContraindicatedKEMCURE DT TABLET is not recommended in women who are pregnant (especially during the last 3 months) or trying to get pregnant as it may harm the baby. Consult your doctor for advice.
Breastfeeding
ContraindicatedKEMCURE DT TABLET is not recommended for use in breastfeeding mothers. Consult your doctor for advice.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy, drowsy, tired or light-headed after taking KEMCURE DT TABLET.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking KEMCURE DT TABLET because you would be more likely to develop stomach problems.
Kidney
Consult your doctorKEMCURE DT TABLET is not recommended for use in patients with severe kidney disease. KEMCURE DT TABLET should be used with caution in patients with other kidney problems. Consult your doctor for advice.
Liver
Use with CautionKEMCURE DT TABLET should be used with caution in patients with impaired liver function, history of liver disease or any biliary problem. Consult your doctor for advice.
Allergy
ContraindicatedDo not take KEMCURE DT TABLET if you are allergic to Ketorolac tromethamine, aspirin or other similar medicines or any of the other ingredients of this medicine.
Lungs
Use with CautionKEMCURE DT TABLET should be used with caution in patients with a family history of asthma, nasal polyps, chronic sinusitis (long-term swelling of the sinus) or hives. Consult your doctor for advice.
Heart Disease
Consult your doctorKEMCURE DT TABLET is not recommended for use if you had or are going to have a heart bypass surgery, have severe uncontrolled heart failure. KEMCURE DT TABLET should be used with caution in patients who have or had high blood pressure, angina, heart attack, congestive heart failure or atherosclerosis (thickening or hardening of your artery walls). Consult your doctor for advice.
Use In Pediatrics
ContraindicatedKEMCURE DT TABLET is not recommended for use in children. The safety and effectiveness of KEMCURE DT TABLET in children and adolescents (below 17 years of age) have not been established. Consult your child’s doctor for advice.
Use In Geriatrics
Use with CautionKEMCURE DT TABLET should be used with caution in elderly patients above 65 years of age. Your doctor may prescribe you lower dosages. Consult your doctor for advice.
Others
KEMCURE DT TABLET is not recommended for use if you:
- have or had peptic ulcer and gastrointestinal bleeding or perforation
- have to undergo any major surgery
- tend to bleed easily
- have cerebrovascular bleeding
- have incomplete haemostasis (blood clotting), high risk of bleeding
- had an asthma attack, hives or other allergic reactions after taking aspirin or any other NSAIDs
- are going to take it for pain, right before or after heart bypass surgery
- smoke
Before taking KEMCURE DT TABLET, inform your physician if you have:
- high cholesterol
- diabetes mellitus or are on a low sugar diet
- poor circulation to your extremities
- pancreatic problems
Interactions
A. Drug-Drug interactions:
Before taking KEMCURE DT TABLET, inform your doctor if you are taking any of the following medicines:
- Antidepressants (Ex. fluvoxamine, sertraline, trazodone, citalopram, fluoxetine, escitalopram, paroxetine, vilazodone)
- lithium (used to manage mania)
- Anti-psychotics (Ex. thiothixene, alprazolam)
- Pain killers (Ex. ibuprofen, indomethacin, ketorolac, aspirin, celecoxib, diclofenac, meloxicam, naproxen)
- methotrexate (medicine used in cancer management)
- Anticoagulants (Ex. warfarin, heparin, clopidogrel)
- Cardiac drugs (Ex. furosemide, hydrochlorothiazide, enalapril, lisinopril, perindopril, ramipril, candesartan, irbesartan, losartan, valsartan, digoxin)
- Antiepileptics (Ex. phenytoin, carbamazepine)
- prednisolone (used to manage autoimmune and inflammatory diseases)
- cyclosporin (used to supress immunity)
- morphine (used in extreme pain)
- oxpentiphylline (used to manage blood flow problems in legs or arms)
- probenecid (used to manage gout)
Overdosage:
If you or anyone accidentally use too much of KEMCURE DT TABLET, consult your doctor immediately or visit the nearby hospital as it may increase the risk of side effects. Symptoms of KEMCURE DT TABLET overdosage may include drowsiness, nausea, vomiting and upper abdomen pain, lethargy.
Synopsis
| Drug | : | Ketorolac tromethamine |
| Pharmacological Category | : | Nonsteroidal Anti-inflammatory Drugs |
| Therapeutic Indication | : | Pain management |
| Dosage Forms | : | Tablet, Dispersible tablet, Injection, Gel, Eye drops, Solution, Opthalmic Solution |
More Information
Storage
- Keep KEMCURE DT TABLET out of reach of children
- Store KEMCURE DT TABLET below 30°C
FAQs About KEMCURE DT TABLET
Q: Can I get stomach ulcers while using KEMCURE DT TABLET?
A: Yes. Stomach ulcers or bleeding is a side effect of [GBNKEWORD] and the risk increases if you are taking medicines called ‘corticosteroids’ and ‘anticoagulants’, longer use, smoking, drinking alcohol, are older in age or have poor health. Consult your doctor for advice.
Q: Can KEMCURE DT TABLET be given to heart patients?
A: KEMCURE DT TABLET is not recommended for use if you had or are going to have a heart bypass surgery, have severe uncontrolled heart failure. KEMCURE DT TABLET should be used with caution in patients who have or had high blood pressure, angina, heart attack, congestive heart failure, atherosclerosis (thickening or hardening of your artery walls). Consult your doctor before taking it. Consult your doctor for advice.
Q: Is KEMCURE DT TABLET safe for use in pregnant women?
A: KEMCURE DT TABLET is not recommended in women who are pregnant (especially during the last 3 months) or trying to get pregnant as it may harm the baby. If you are pregnant, think you may be pregnant or are planning for a child, contact your doctor before taking KEMCURE DT TABLET.
Q: Can KEMCURE DT TABLET be given to children?
A: KEMCURE DT TABLET is not recommended for use in children. The safety and effectiveness of KEMCURE DT TABLET in children and adolescents (below 17 years of age) have not been established. Consult your child’s doctor for advice. The doctor will determine a proper dose of KEMCURE DT TABLET or select a suitable alternative management for your child.
Q: Does KEMCURE DT TABLET causes dizziness?
A: Yes. KEMCURE DT TABLET causes dizziness. When you feel dizzy, lie or sit down immediately, lie in a dark and quite place with eyes closed. Discuss with your doctor if the dizziness doesn’t improve or worsen.
Q: What does KEMCURE DT TABLETcontain?
A: KEMCURE DT TABLET contains Ketorolac tromethamine, which belongs to the group of medicines called Painkillers.
Q: What is KEMCURE DT TABLET used for?
A: It is indicated for the short-term management of sudden moderately severe pain that occurs usually after any surgical procedure, musculoskeletal pain and other pain conditions.
Q: How does KEMCURE DT TABLET work?
A: KEMCURE DT TABLET works by blocking the effects of a substance produced during injury which causes inflammation and pain (prostaglandin) and it also inhibits the pain signals between the brain and nerve endings.
Q: How to take KEMCURE DT TABLET?
A: Take KEMCURE DT TABLET as advised by your physician. It can be taken with or without food.
For Tablet, Capsule: Swallow KEMCURE DT TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse KEMCURE DT TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution.
Your doctor will decide the correct dose and duration of KEMCURE DT TABLET therapy for you depending upon your age, body weight and disease condition. Continue to take KEMCURE DT TABLET for the stipulated duration prescribed by your doctor to achieve better results.
References
1. KD. Tripathi. NSAIDs and Antipyretic-Analgesics. Essentials of medical pharmacology. Eighth edition. 2019. Page-218.
2. Ahmad N. Mahmoodi; Peggy Y. Kim. Ketorolac. NIH National Library of Medicine, National center for biotechnology information. StatPearls [Internet]. April 2022. [Accessed on 12th August 2024] https://www.ncbi.nlm.nih.gov/books/NBK545172/
3. Tom Mallinson. A review of ketorolac as a prehospital analgesic. ReserachGate. December 2017. [Accessed on 12th August 2024] https://www.researchgate.net/publication/321640488_A_review_of_ketorolac_as_a_prehospital_analgesic
4. Innova Cap Tab Ltd. Torodent DT (Ketorolac Trimethamine). Ciplamed. [Revised in September 2020]. [Accessed on 12th August 2024] https://ciplamed.com/content/torodent-dt
5. Apotex Inc. Apo-ketorolac (Ketorolac Trimethamine). [Revised in October 2017] [Accessed 12th August 2024] https://pdf.hres.ca/dpd_pm/00041526.PDF
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