Introduction About IZEB CREAM

IZEB CREAM contains Eberconazole which belongs to the group of medicines called Topical Antifungals. It is used in the management of dermatophytic fungal skin infections such as candidiasis (yeast infection), fungal infection of skin & skin folds, fungal infection in between fingers & fungal infection of the groin region which may include Tinea corporis (ringworm), Tinea cruris (Jock itch), and Tinea pedis (Athlete’s foot).

Fungal infection is a skin disease in which a fungus attacks the tissue and causes infection which may present as reddening of skin or a rash.

Your doctor may also advise you to follow personal hygiene habits such as not sharing used clothes and washing your hands before and after managing the infected area to manage the spread of infection to another area or to another person.

Before using IZEB CREAM, inform your doctor if you have any liver, kidney, lung or heart disease. Do not use IZEB CREAM if you have had an allergic reaction to Eberconazole.

IZEB CREAM should be used with caution among pregnant and breastfeeding women. There is no specific data available on the use of IZEB CREAM in children, hence, consult the doctor for advice.

The most common side effects of using IZEB CREAM are erythema and itching in the application area. Contact your doctor if any of the symptoms worsen.

Uses Of IZEB CREAM

It is used in the management of dermatophytic skin infections such as:

• Tinea corporis (ringworm)
• Tinea cruris (Jock itch)
• Tinea pedis (Athlete’s foot)
• candidiasis

How IZEB CREAM Works

IZEB CREAM works by killing and stopping the growth of the fungi by destroying its cell membrane, thereby managing skin infection. As a result, it manages the fungal infection of the skin.

How to use IZEB CREAM

Always use IZEB CREAM as directed by your physician. It is for external use only. Dry the infected part of the skin before using IZEB CREAM. Wash your hands before and after using this medicine. Do not apply in eyes or on mucous membranes. Your doctor will decide the correct dose, duration, and frequency of IZEB CREAM for you depending on the existing conditions, etc.

Side Effects Of IZEB CREAM

How To Manage Side Effects

Application Site Reactions

Hot water makes your skin irritated, so avoid taking hot showers. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. To soothe and hydrate the irritated skin, apply moisturizers. Contact your doctor if itching worsens.

Warning & Precautions

Pregnancy

Use with Caution

IZEB CREAM should be used with caution in pregnant women as there is not sufficient data on the use of IZEB CREAM in this group. Consult your doctor before using it.

Breastfeeding

Use with Caution

IZEB CREAM should be used with caution for use in breastfeeding women as it is not known if it passes through breast milk. Consult your doctor before using it.

Driving and Using Machines

Use with Caution

IZEB CREAM does not affect the ability to drive and use machines.

Allergy

Use with Caution

Do not use IZEB CREAM if you are allergic to Eberconazole, any other imidazole antifungal such as miconazole, clotrimazole, or any of the other ingredients of this medicine.

Interactions

A. Drug-Drug interactions:

Before using IZEB CREAM, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, non-prescription or any herbal medicine.

Overdosage:

If you or anyone else apply too much or has accidental ingestion and systemic exposure of IZEB CREAM, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep IZEB CREAM out of reach of children
• Store IZEB CREAM at a temperature, not more than 30°C

FAQs About IZEB CREAM

Why is IZEB CREAM prescribed?

IZEB CREAM is used for the management of dermatophytic fungal skin infections such as candidiasis, Tinea corporis (ringworm), Tinea cruris (Jock itch), and Tinea pedis (Athlete’s foot). Fungal infection is a skin disorder in which the tissue is attacked by the fungus and causes infection. Fungal infections may be infectious (spread from one person to another).

Is IZEB CREAM an antibiotic?

No. IZEB CREAM is an antifungal medicine which works by killing and stopping the growth of the fungi by destroying its cell membrane, thereby managing skin infection. As a result, it manages the fungal infection of the skin.

Can IZEB CREAM be used during pregnancy and breastfeeding?

IZEB CREAM should be used with caution in pregnant and breastfeeding women. Consult your doctor before using it.

What precautions shall I follow while using IZEB CREAM?

IZEB CREAM should not be used in and around the eyes. If it comes in contact with eyes, wash with plenty of water. IZEB CREAM should not be used under tight bandages that does not allow air to pass as this may cause growth of yeast and cause skin irritation.

Who should not use IZEB CREAM?

Do not use IZEB CREAM if you are allergic to Eberconazole, any other imidazole antifungal such as miconazole, clotrimazole, or any of the other ingredients of this medicine. Ask for your doctor’s advice before using IZEB CREAM.

References

1. Sean C Sweetman. Antifungals. Martindale-The Complete Drug Reference. Thirty Sixth Edition. 2009. Page – 530.

2. Latha Subramanya, Moodahadu Bangera, Jacintha Martis, Rajan Mittal, et.al. Eberconazole - Pharmacological and Clinical review. Indian Journal of Dermatology, Venerology, and Leprology. 2012. [Accessed on 10th June 2022] https://ijdvl.com/eberconazole-pharmacological-and-clinical-review/

3. Jayakar Thomas, Siddhartha Das, Sunil Ghate, Manas Chatterjee, Sharad Teltumde, Sujeet Narayan Charugulla, Suyog Mehta, Amey Mane, Rahul Rathod, Ravindra Kale. Effectiveness and safety of eberconazole 1% cream in Indian patients with Tinea corporis and Tinea cruris: a prospective real-world study. Indisan Journal of Research in Dermatology. December 2020. [Accessed on 10th June 2022] https://www.ijord.com/index.php/ijord/article/view/1197

4. Jyoti Sharma, Jyoti Kaushal, and Kamal Aggarwal. A Comparative Study of Efficacy and Safety of Eberconazole versus Terbinafine in Patient of Tinea Versicolor. NIH Natinal Library of Medicine, National Institute of Biotechnology Information. Pubmed Central. January 2018. [Accessed on 10th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838755/

5. Barbanoj MJ, Antonijoan R, García-Gea C, Puntes M, Gich I, Jané F. Eberconazole cream: topical and general tolerability, sensitization potential, and systemic availability. May 2005. [Accessed 10th June 2022] https://europepmc.org/article/med/16082423

6. Laboratorios Salvat, SA, March 2004 [Revised March 2009] [Accessed on 10th June 2022] https://cima.aemps.es/cima/dochtml/ft/65966/FT_65966.html

7. Curatio Healthcare. Crurix cream. [Accessed on 10th June 2022] https://curatiohealthcare.com/product/crurix/

8. Leeford Healthcare. Eberford. [Accessed on 10th June 2022] https://www.leeford.in/product/1261/eberford

Author Details

Written By Dr. Priyanka Goel - BDS

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 27 Jan 2023 | 12:03 PM(IST)