Introduction About HYDRAZIDE 12.5MG TABLET

HYDRAZIDE 12.5MG TABLET contains Hydrochlorothiazide which belongs to the group of medicines called Diuretics. It is as an adjuvant therapy in managing edema (fluid accumulation) that is caused due to heart failure, liver inflammation (Ex. liver cirrhosis), kidney problems or due to intake of steroid medications. It can also be used in the management of hypertension (high blood pressure) either alone or in combination with other medications.

During management with HYDRAZIDE 12.5MG TABLET your doctor will constantly monitor your kidney functions, blood pressure, electrolyte levels and blood sugar levels to avoid the risk of unwanted side effects.

Before taking HYDRAZIDE 12.5MG TABLET inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have diabetes, asthma, diabetes, low blood potassium levels, gout or electrolyte imbalance as a precaution.

Consult your doctor before taking HYDRAZIDE 12.5MG TABLET if you are pregnant or breastfeeding. The most common side effects of taking HYDRAZIDE 12.5MG TABLET are headache, dizziness, stomach pain, constipation, muscle spasm, blurred vision and impotence. Contact your doctor if any of these side effect worsens.

Uses Of HYDRAZIDE 12.5MG TABLET

• Manage oedema (fluid accumulation in the body parts which causes swelling)
• Manage hypertension (high blood pressure)

How HYDRAZIDE 12.5MG TABLET Works

HYDRAZIDE 12.5MG TABLET is a diuretic. It acts by removing excess water from the body in the form of urine. This reduces swelling of body parts and manages fluid accumulation. It also reduces the thickness of blood which reduces the strain on the heart and helps the heart to pump blood more smoothly with less pressure.

How to use HYDRAZIDE 12.5MG TABLET

Take HYDRAZIDE 12.5MG TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Try to take HYDRAZIDE 12.5MG TABLET at the same time each day.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Continue to take HYDRAZIDE 12.5MG TABLET for the stipulated duration instructed by your doctor without any interruption to achieve better results.

Side Effects Of HYDRAZIDE 12.5MG TABLET

How To Manage Side Effects

Constipation

Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Nausea And Vomiting

Take HYDRAZIDE 12.5MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.

Warning & Precautions

Pregnancy

Monitoring required

HYDRAZIDE 12.5MG TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.

Breastfeeding

Use with Caution

HYDRAZIDE 12.5MG TABLET may pass through breast milk. Therefore, it should be used with caution in breastfeeding women. Consult your doctor for advice before taking it.

Driving and Using Machines

Use with Caution

Do not drive or handle any heavy tools or machines if you experience dizziness or drowsiness after taking HYDRAZIDE 12.5MG TABLET.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking HYDRAZIDE 12.5MG TABLET as it might make you feel dizzier and drowsier.

Kidney

Use with Caution

HYDRAZIDE 12.5MG TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.

Liver

Use with Caution

HYDRAZIDE 12.5MG TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.

Allergy

Contraindicated

Do not take HYDRAZIDE 12.5MG TABLET if you are allergic to Amlodipine or Hydrochlorothiazide.

Lungs

Use with Caution

HYDRAZIDE 12.5MG TABLET should be used with caution in patients with asthma or any breathing problems. Therefore, consult your doctor before taking it.

Use In Pediatrics

Consult your doctor

There is no proper information regarding the use of HYDRAZIDE 12.5MG TABLET in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice before taking it.

Use In Geriatrics

Use with Caution

HYDRAZIDE 12.5MG TABLET should be used with caution in the elderly patients. Therefore, consult your doctor before taking it.

Interactions

A. Drug - Drug interactions:

Before taking HYDRAZIDE 12.5MG TABLET, inform your doctor if you are taking any of the following medicines such as:

• other medicines used to manage high blood pressure or angina (Ex. diltiazem, verapamil)
• medicines that can depress the brain such as barbiturates (Ex. phenobarbital)
• narcotic drugs (used for pain relief) such as morphine, fentanyl, pethidine
• medicines used to manage diabetes (such as insulin, metformin, glimepiride)
• medicines used to reduce blood cholesterol levels (such as cholestyramine, colestipol)
• corticosteroids (used to manage inflammation) Ex. prednisolone
• noradrenaline (a medicine used to increase blood pressure)
• tubocurarine, dantrolene (medicines used to relax muscles)
• medicines used for pain and inflammation (such as ibuprofen or indomethacin)
• lithium (a medicine used to manage metal illnesses)

Overdosage:

If you or anyone else accidentally took more HYDRAZIDE 12.5MG TABLET, consult your doctor immediately. Overdosage may cause electrolyte imbalance and dehydration.

Synopsis

More Information

• Keep HYDRAZIDE 12.5MG TABLET out of reach of children
• Store HYDRAZIDE 12.5MG TABLET at room temperature

FAQs About HYDRAZIDE 12.5MG TABLET

Q: What are the uses of HYDRAZIDE 12.5MG TABLET?

A: HYDRAZIDE 12.5MG TABLET is prescription medicine used to manage oedema and hypertension.

Q: What type of a medicine is HYDRAZIDE 12.5MG TABLET?

A: HYDRAZIDE 12.5MG TABLET is a diuretic. It acts by removing excess water from the body in the form of urine. This reduces swelling of body parts and manages fluid accumulation. It also reduces the thickness of blood which reduces the strain on the heart and helps the heart to pump blood more smoothly with less pressure.

Q: What happens when I stop taking HYDRAZIDE 12.5MG TABLET?

A: Do not stop taking HYDRAZIDE 12.5MG TABLET without consulting your doctor as your symptoms may re-appear once again. Make sure to take HYDRAZIDE 12.5MG TABLET for the stipulated duration recommended by your doctor to achieve maximum results.

Q: What is the best time to take HYDRAZIDE 12.5MG TABLET?

A: HYDRAZIDE 12.5MG TABLET can be taken with or without meals. Your doctor will decide the best time for you to take HYDRAZIDE 12.5MG TABLET based on your age, body weight and disease condition.

Q: What to do if I forgot to take a dose of HYDRAZIDE 12.5MG TABLET?

A: If you forgot to take a dose of HYDRAZIDE 12.5MG TABLET, take it as soon as you remember. However, if it is time for the next dose of HYDRAZIDE 12.5MG TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of HYDRAZIDE 12.5MG TABLET to compensate the missed ones.

Q: What precautions should be followed while taking HYDRAZIDE 12.5MG TABLET?

A: Before taking HYDRAZIDE 12.5MG TABLET, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have diabetes, asthma, dehydration, gout or electrolyte imbalance. Consult your doctor before taking HYDRAZIDE 12.5MG TABLET if you are pregnant or breastfeeding. Regularly visit your doctor and take all the necessary blood test recommended by your doctor without fail.

Q: Can I consume alcohol while taking HYDRAZIDE 12.5MG TABLET?

A: Avoid consumption of alcohol while taking HYDRAZIDE 12.5MG TABLET as it might make you feel dizzier and drowsier.

Q: What happens if I accidentally take more HYDRAZIDE 12.5MG TABLET?

A: If you or anyone else accidentally took more HYDRAZIDE 12.5MG TABLET, consult your doctor immediately. Overdosage may cause severe dehydration.

Q: Can I take HYDRAZIDE 12.5MG TABLET daily?

A: Take HYDRAZIDE 12.5MG TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take HYDRAZIDE 12.5MG TABLET every day or not.

Q: Is HYDRAZIDE 12.5MG TABLET safe to use in diabetic patients?

A: HYDRAZIDE 12.5MG TABLET may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before taking HYDRAZIDE 12.5MG TABLET as a precaution. Your doctor will closely monitor you blood sugar levels to avoid the risk of side effects.

Q: What are the side effects of HYDRAZIDE 12.5MG TABLET?

A: The most common side effects of taking HYDRAZIDE 12.5MG TABLET are headache, dizziness, stomach pain, constipation, muscle spasm, blurred vision and impotence. Contact your doctor if any of these side effect worsens.

Q: Can I stop taking HYDRAZIDE 12.5MG TABLET once my symptoms subside?

A: No. Do not stop taking HYDRAZIDE 12.5MG TABLET without consulting your doctor. As hypertension is a chronic condition, long term management may be necessary to control its symptoms. Therefore, take HYDRAZIDE 12.5MG TABLET as advised by your doctor for the stipulated duration. Premature discontinuation of therapy may increase your blood pressure once again.

Q: Can HYDRAZIDE 12.5MG TABLET be taken during pregnancy?

A: HYDRAZIDE 12.5MG TABLET should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before taking it.

Q: Is HYDRAZIDE 12.5MG TABLET safe to use in kidney disease?

A: HYDRAZIDE 12.5MG TABLET should be used with caution in patients with kidney problems (such as kidney transplant, narrowing of renal arteries). Your doctor will access your health condition and suggest a suitable dose for you.

Q: Can the use of HYDRAZIDE 12.5MG TABLET affect the liver?

A: Yes. HYDRAZIDE 12.5MG TABLET may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before taking it.

References

1. KD. Tripathi. Antihypertensive Drugs. Diuretics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 559 & 582.

2. Linda L. Herman; Khalid Bashir. Hydrochlorothiazide. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. July 2022. [Accessed on 11th February 2023].

3. Mylan Pharmaceuticals Inc. U.S. Food and Drug Administration. [Revised in May 2011] [Accessed on 11th February 2023]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/040735s004,040770s003lbl.pdf

Useful Diagnostic Tests

• Kidney Function Test