Introduction About HYCLO 0.1% EYE DROPS

HYCLO 0.1% EYE DROPS contains Cyclosporin which belongs to the group of medicines called Immunosuppressants.  It is used to manage severe dry eye syndrome (keratoconjunctivitis sicca) in children and in adolescents (aged between 4-18 years).

Dry Eye Syndrome (also known as keratoconjunctivitis sicca) is an allergic eye condition that affects the transparent layer in the front part of the eye and the thin membrane covering the front part of the eye. It is characterized by excessive eye dryness, redness, itching, inflammation and discomfort. Persons having dry eye syndrome do not produce sufficient tears to lubricate and nourish the eyes.

HYCLO 0.1% EYE DROPS is for ophthalmic use only. Wash your hands before and after application. Avoid touching the tip of the container with your mouth, nose or other parts of body to avoid contamination.

If you wear soft contact lenses, make sure to remove them before using HYCLO 0.1% EYE DROPS. Consult your doctor about the usage of contact lenses while undergoing management for dry eyes.

Before using HYCLO 0.1% EYE DROPS inform your doctor if you have any other eye conditions apart from dry eye syndrome such as eye infection or glaucoma. HYCLO 0.1% EYE DROPS is not recommended for use in patients having cancer in and around the eye areas. Consult your doctor before using HYCLO 0.1% EYE DROPS if you are pregnant or breastfeeding.

The most common side effects of using HYCLO 0.1% EYE DROPS are eye pain, redness, irritation or discomfort, watery eyes and blurred vision. Consult your doctor if they trouble you.

Uses Of HYCLO 0.1% EYE DROPS

• Manage severe dry eye syndrome

How HYCLO 0.1% EYE DROPS Works

HYCLO 0.1% EYE DROPS is an immunosuppressive agent. Following application on the eyes, it blocks the release of certain chemicals in the eye (such as T-cells, interleukins and cytokines) that causes eye inflammation, allergies and discomfort. As a result, it reduces inflammation and swelling on the eye and keeps your eyes lubricated by allowing your eye to produce tears.

How to use HYCLO 0.1% EYE DROPS

Use HYCLO 0.1% EYE DROPS as advised by your physician. It is for ophthalmic use only. Wash your hands before application. Tilt your head slightly backwards and place the tip of the container close to your eyes.

Gently pull your lower eyelid and instil few drops of the medicine as directed by your physician. Close your eyes and gently press the inner corner of your eye for 2 minutes. Repeat the same for the other eye if required.

Do not touch the tip of the container with your eyes, eyelids or areas around your eyes or fingers, to avoid contamination. Avoid wearing contact lenses while undergoing therapy for dry eyes.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop using HYCLO 0.1% EYE DROPS unless your doctor tells you to stop.

Side Effects Of HYCLO 0.1% EYE DROPS

How To Manage Side Effects

Eye irritation, redness or discomfort:

Avoid watching direct light sources. Do not strain your eyes too much. Protect your eyes from bright light while going outdoors using sunglasses. Consult your doctor if this side effect bothers you.

Blurred vision:

Close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.

Warning & Precautions

Pregnancy

HYCLO 0.1% EYE DROPS is not recommended for use in pregnant women. Therefore, consult your doctor before using it. Women of childbearing potential should use suitable contraceptive to manage pregnancy while undergoing therapy with HYCLO 0.1% EYE DROPS.

Breastfeeding

HYCLO 0.1% EYE DROPS should be used with caution in breast-feeding women. Therefore, consult your doctor before using it.

Driving and Using Machines

HYCLO 0.1% EYE DROPS may temporarily blur your vision. Therefore, do not drive or handle any heavy tools or machines if you experience blurred vision after applying HYCLO 0.1% EYE DROPS.

Alcohol

Consumption of alcohol is not recommended during management with HYCLO 0.1% EYE DROPS.

Allergy

Do not use HYCLO 0.1% EYE DROPS if you are allergic to cyclosporin.

Interactions

A. Drug - Drug interactions:

Before using HYCLO 0.1% EYE DROPS, inform your doctor if you are taking any of the following medicine:

• eye drops containing steroids (Ex. dexamethasone)
• medicines used to manage glaucoma (Ex. latanoprost, travoprost, tafluprost, bimatoprost)

Overdosage:

If you or anyone else accidentally used excessive amount of HYCLO 0.1% EYE DROPS, rinse your eyes with plain water to ease the irritation. If you irritation persists, consult your doctor.

Synopsis

More Information

• Keep HYCLO 0.1% EYE DROPS out of reach of children
• Store HYCLO 0.1% EYE DROPS at room temperature

FAQs About HYCLO 0.1% EYE DROPS

What is the use of HYCLO 0.1% EYE DROPS?

HYCLO 0.1% EYE DROPS is used to manage severe dry eye syndrome (keratoconjunctivitis sicca) in children and in adolescents (aged between 4-18 years).

How HYCLO 0.1% EYE DROPS works?

HYCLO 0.1% EYE DROPS is an immunosuppressive agent. Following application on the eyes, it blocks the release of certain chemicals in the eye (such as T-cells, interleukins and cytokines) that causes eye inflammation, allergies and discomfort. As a result, it reduces inflammation and swelling on the eye and keeps your eyes lubricated by allowing your eye to produce tears.

How to take HYCLO 0.1% EYE DROPS?

Wash your hands before application. Tilt your head slightly backwards and place the tip of the container close to your eyes. Gently pull your lower eyelid and instil few drops of the medicine as directed by your physician. Close your eyes and gently press the inner corner of your eye for 2 minutes. Repeat the same for the other eye if required.

How long should I use HYCLO 0.1% EYE DROPS?

You need to use HYCLO 0.1% EYE DROPS for the stipulated duration prescribed by your doctor. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Is HYCLO 0.1% EYE DROPS safe?

HYCLO 0.1% EYE DROPS is safe at doses prescribed by the physician. Therefore, do not alter the dose of HYCLO 0.1% EYE DROPS without consulting your doctor.

Can I stop using HYCLO 0.1% EYE DROPS without consulting your doctor?

No. You should not stop using HYCLO 0.1% EYE DROPS without consulting your doctor as it may cause the symptoms to re-appear. Therefore, use HYCLO 0.1% EYE DROPS for the stipulated duration recommended by your doctor to achieve maximum results.

Will using a higher dose of HYCLO 0.1% EYE DROPS be more effective?

No, using a higher dose of HYCLO 0.1% EYE DROPS will not be effective rather it can lead to toxicity. Always apply the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.

Can HYCLO 0.1% EYE DROPS be used in pregnant women?

HYCLO 0.1% EYE DROPS is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before using it.

What are the common side effects of using HYCLO 0.1% EYE DROPS?

The most common side effects of using HYCLO 0.1% EYE DROPS are eye pain, redness, irritation or discomfort, watery eyes and blurred vision. Consult your doctor if they trouble you.

What to do if I forgot to apply HYCLO 0.1% EYE DROPS?

If you forgot to apply a dose of HYCLO 0.1% EYE DROPS, apply it as soon as you remember. However, if it is time for the next dose of HYCLO 0.1% EYE DROPS, skip the missed dose and apply the next one regularly. Do not apply a double dose of HYCLO 0.1% EYE DROPS to compensate the missed ones.

How long will it take for HYCLO 0.1% EYE DROPS to heal my condition?

You need to apply HYCLO 0.1% EYE DROPS as long as your doctor prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Can I use other eye medicines while using HYCLO 0.1% EYE DROPS?

Avoid using any other eye medicines along with HYCLO 0.1% EYE DROPS without consulting your doctor as it may increase the risk of side effects.

Can HYCLO 0.1% EYE DROPS reduce conjunctivitis?

Yes. HYCLO 0.1% EYE DROPS can be used to manage allergic eye conditions (such as allergic conjunctivitis, keratoconjunctivitis, etc.).

Can the use of HYCLO 0.1% EYE DROPS cause blurred vision?

Yes. HYCLO 0.1% EYE DROPS may cause blurred vision after application. If your vision becomes blur, close your eyes for some time and rest. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.

References

1. KD. Tripathi. Immunosuppressant Drugs. Essentials of Medical pharmacology. 7th Edition. 2013. Page – 878.

2. Philip Ames and Anat Galor. Cyclosporine ophthalmic emulsions for the treatment of dry eye: a review of the clinical evidence. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on 22nd November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420022/

3. Clyde Schultz. Safety and Efficacy of Cyclosporine in the Treatment of Chronic Dry Eye. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. June 2014. [Accessed on 22nd November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076204/

4. Santen Oy. Electronic Medicines Compendium (EMC) [Revised in January 2022] [Accessed on 22nd November 2022] https://www.medicines.org.uk/emc/files/pil.9491.pdf

5. Central Drugs Standard Control Organization. Cyclosporin 0.05% eye drops. March 2003. Cyclosporin Eye drops (0.1%). June 2006. [Accessed on 22nd November 2022] https://cdscoonline.gov.in/CDSCO/Drugs