Introduction About HILIN GM TABLET

HILIN GM TABLET contains a combination of Diacerein and Gucosamine sulfate potassium chloride which belongs to the group of medicines called Nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to manage osteoarthritis of the knee.

Osteoarthritis is a type of joint degeneration that occurs when the protective cartilage that cushions the ends of the bones wears down over time and generates symptoms such as stiffness, pain in movement, tenderness, swelling, bone spurs, crackling sound while walking. 

Before taking HILIN GM TABLET inform your doctor if you have liver, kidney, heart, intestine, abdominal disease, asthma, or suffer from impaired glucose tolerance, or severe issues with the joints. Avoid consumption of alcohol during this management as it can increase liver damage.

HILIN GM TABLET is not recommended for use in pregnant and breastfeeding women. It is not recommended for use in children and adolescents below 18 years of age. HILIN GM TABLET should be used with caution in the elderly above 65 years of age.

The most common side effects of taking HILIN GM TABLET are diarrhea, abdominal pain, flatulence, headache, and nausea. Consult your doctor if symptoms do not show improvement.

Uses Of HILIN GM TABLET

• Manage osteoarthritis of the knee

How HILIN GM TABLET Works

HILIN GM TABLET works by relieving symptoms of osteoarthritis in which diacerein works by blocking the actions of interleukin-1 beta, a protein involved in the inflammation and destruction of cartilage that plays a role in the development of symptoms of osteoarthritis and glucosamine sulfate potassium chloride delays many inflammation-induced catabolic processes in the cartilage and promotes the formation of cartilage.

How to use HILIN GM TABLET

Take HILIN GM TABLET as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration depending on your age, body weight and disease condition.

Side Effects Of HILIN GM TABLET

How To Manage Side Effects

Bloating

Eat smaller and more frequent meals, and exercise regularly. If the symptom does not show improvement, consult your doctor.

Constipation

Eat lots of fiber-rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. If the symptom does not show improvement, consult your doctor.

Diarrhea

Drink lots of water or fruit juice to keep yourself hydrated. If the symptom does not show improvement, consult your doctor.

Headache

Avoid bright lights, drink more water and take a rest. If the symptom does not show improvement, consult your doctor.

Nausea And Vomiting

Stick to simple meals. Avoid eating oily or spicy food. If the symptom does not show improvement, consult your doctor.

Stomach Pain

Eat and drink slowly. Keep a heating pad on your stomach. If the symptom does not show improvement, consult your doctor.

Warning & Precautions

Pregnancy

Contraindicated

HILIN GM TABLETis not recommended for use in pregnancy or for women planning to be pregnant. Consult your doctor before taking it.

Breastfeeding

Contraindicated

HILIN GM TABLETis not recommended for use in breastfeeding women. Consult your doctor before taking it.

Driving and Using Machines

Use with Caution

The effect of HILIN GM TABLET on driving and using machines has not been established yet, however, if you feel dizzy or sleepy abstain from driving.

Alcohol

Contraindicated

Do not consume alcohol while taking HILIN GM TABLET as it can make increase your liver problems.

Kidney

Use with Caution

HILIN GM TABLETshould be used with caution in patients with kidney disease. Consult your doctor before taking it.

Liver

Consult your doctor

HILIN GM TABLETis not recommended for use in patients with liver problems. HILIN GM TABLET should be used with caution in patients with liver disease. Consult your doctor before taking it.

Allergy

Contraindicated

Do not take HILIN GM TABLET if you are allergic to Diacerein or Gucosamine sulfate potassium chloride or any other ingredients of this medicine.

Lungs

Use with Caution

HILIN GM TABLET should be used with caution in patients with asthma. Consult your doctor before taking it.

Heart Disease

Use with Caution

HILIN GM TABLET should be used with caution in patients with heart disease. Consult your doctor before taking it.

Use In Pediatrics

Contraindicated

HILIN GM TABLET is not recommended for use in children and adolescents below 18 years of age.  Consult your doctor before taking it.

Use In Geriatrics

Use with Caution

HILIN GM TABLET should be used with caution in the elderly above 65 years of age as they are more vulnerable to diarrheal problems and other side effects. Consult your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking HILIN GM TABLET, inform your doctor if you are taking any of the following medicine:

• warfarin (a medicine used to thin the blood)
• medicines for diabetes (Ex. metformin, glipizide)
• tetracycline (an antibiotic against bacterial infections)
• antacids (medicines for managing stomach acidity)
• a diuretic or cardiac glycosides (Ex. digitoxin, digoxin)
• laxatives (Ex. bisacodyl)

Overdosage:

If you or anyone else accidentally take too much of HILIN GM TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are intense diarrhea, dizziness, headache, nausea, vomiting, constipation, and joint pain.

Synopsis

More Information

• Keep HILIN GM TABLET out of reach from children
• Store at room temperature

FAQs About HILIN GM TABLET

Q: What is HILIN GM TABLET used for?

A: HILIN GM TABLET is used to manage osteoarthritis of the knee. Osteoarthritis is a type of joint degeneration that occurs when the protective cartilage that cushions the ends of the bones wears down over time and generates symptoms such as stiffness, and pain in movement.

Q: How does HILIN GM TABLET work?

A: HILIN GM TABLET works by relieving symptoms of osteoarthritis in which diacerein works by blocking the actions of interleukin-1 beta, a protein involved in the inflammation and destruction of cartilage that plays a role in the development of symptoms of osteoarthritis and glucosamine sulfate potassium chloride delays many inflammation-induced catabolic processes in the cartilage and promotes the formation of cartilage.

Q: What if I accidentally take more of HILIN GM TABLET?

A: If you or anyone else accidentally take too much of HILIN GM TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are intense diarrhea, dizziness, headache, nausea, vomiting, constipation, and joint pain.

Q: Can HILIN GM TABLET be used in elderly patients?

A: HILIN GM TABLETshould be used with caution in the elderly above 65 years of age as they are more vulnerable to diarrheal problems and other side effects. Consult your doctor before taking.

Q: Can HILIN GM TABLET be used in children?

A: HILIN GM TABLETis not recommended for use in children and adolescents below 18 years of age.  Consult your doctor before taking this medicine.

References

1. KD Tripathi. Nonsteroidal Antiinflammatory Drugs and Antipyretic-Analgesics. Essentials of medical pharmacology. Eighth Edition. 2019. Page –220-224.

2. Jörg Jerosch. Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids. [Accessed on 5th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150191/

3. Johanne Martel-Pelletier. Effects of Diacerein at the Molecular Level in the Osteoarthritis Disease Process. [Accessed on 5th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383474/

4. Chanelle Medical. Health Products Regulatory Authority (HPRA). [Revised in May 2016] [Accessed on 5th August 2022] https://www.hpra.ie/img/uploaded/swedocuments/2171814.PA1521_003_003.1a94fbbc-f593-4a32-a58c-5f8f8bb39b75.000001PIL%201500mg.160824.pdf

5. Chanelle Medical. Health Products Regulatory Authority (HPRA). [Revised in May 2016] [Accessed on 5th August 2022] https://www.hpra.ie/img/uploaded/swedocuments/2171814.PA1521_003_002.cb4ba0a2-1887-4c40-afe6-e19cea656342.000001750mg%20PIL%20.160824.pdf

6. TRB PHARMA S.A. Diacerein [Revised in April 2019] [Accessed on 5th August 2022] https://myhealthbox.eu/en/view/3364878/1066595e9806313ef81279755226ab79/leaflet

7. Trima Israel Pharmaceutical Products Maabarot Ltd. Diacerein. [Revised in November 2015] [Accessed on 5th August 2022] https://myhealthbox.eu/en/view/3529427/469334cbb76f29e848cd1e9f1a64d1ac/leaflet

Author Details

Written By Dr. Dhivakaran R - BDS

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 24 Feb 2023 | 04:08 PM(IST)