Introduction About HIGATI EYE OINTMENT

HIGATI EYE OINTMENT contains Gatifloxacin which belongs to the group of medicines called Antibiotics. It is used to manage bacterial conjunctivitis caused by strains of aerobic gram-positive bacteria (Ex. Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus mitis group, Streptococcus oralis) and aerobic gram-negative bacteria (Ex. Haemophilus influenzae).

HIGATI EYE OINTMENT should be used with caution in pregnant and breastfeeding women as insufficient data is available on this.

HIGATI EYE OINTMENT is not recommended for children below 1 year of age. Contact your doctor before using.

The most common side effects of using HIGATI EYE OINTMENT include conjunctival irritation, increased lacrimation, keratitis, papillary conjunctivitis. Contact your doctor if the symptoms aggravate.

Uses Of HIGATI EYE OINTMENT

• Used to manage bacterial conjunctivitis

How HIGATI EYE OINTMENT Works

HIGATI EYE OINTMENT works by inhibiting DNA gyrase (an enzyme that helps in replication, transcription and repair of bacterial DNA) and topoisomerase IV (an enzyme that helps in portioning of chromosomal DNA during bacterial cell division).

How to use HIGATI EYE OINTMENT

Always use HIGATI EYE OINTMENT as advised by your physician. The dose and duration of using the medicine will be decided by your doctor depending on your age, body weight and disease severity.

Side Effects Of HIGATI EYE OINTMENT

Warning & Precautions

Pregnancy

There is no proper information about the use of HIGATI EYE OINTMENT in pregnant women. Consult your doctor before using.

Breastfeeding

There is no proper information about the use of HIGATI EYE OINTMENT in breastfeeding women. Consult your doctor before using.

Allergy

Do not use HIGATI EYE OINTMENT if you are allergic to Gatifloxacin or any other components of this medicine.

Interactions

A. Drug-Drug Interactions:

Tell your doctor, before applying HIGATI EYE OINTMENT if you are taking:

• theophylline (manages breathing conditions)
• other quinolones medicines
• warfarin (manages blood clot)

Overdosage:

If you accidentally use too much HIGATI EYE OINTMENT, contact your doctor immediately.

Synopsis

More Information

• Keep HIGATI EYE OINTMENT out of sight and reach of children
• Store HIGATI EYE OINTMENT below 25°C

FAQs About HIGATI EYE OINTMENT

Is HIGATI EYE OINTMENT safe for use during pregnancy?

HIGATI EYE OINTMENT should be used with caution in pregnant and breastfeeding women as insufficient data is available on this. Contact your doctor before using.

What are the side effects of HIGATI EYE OINTMENT?

The most common side effects of using HIGATI EYE OINTMENT include conjunctival irritation, increased lacrimation, keratitis, papillary conjunctivitis. Contact your doctor if the symptoms aggravate.

What is HIGATI EYE OINTMENT used for?

It is used to manage bacterial conjunctivitis caused by strains of aerobic gram-positive bacteria (Ex. Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus mitis group, Streptococcus oralis) and aerobic gram-negative bacteria (Ex. Haemophilus influenzae).

What is the mechanism of action of HIGATI EYE OINTMENT?

Gatifloxacin works by inhibiting DNA gyrase (an enzyme that helps in replication, transcription and repair of bacterial DNA) and topoisomerase IV (an enzyme that helps in portioning of chromosomal DNA during bacterial cell division).

References

1. K.D. Tripathi. Sulfonamides, Cotrimoxazole and Quinolones. Essentials of Medical Pharmacology. 7th Edition. 2013. Page 713.

2. Chambers HF, Deck DH. Sulfonamides, Trimethoprim, & Quinolones. Basic and Clinical Pharmacology. 11th ed. 2009. Page - 819.

3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. 2015. Page - 616.

4. Allergan India Pvt Ltd. Gatifloxacin Eye Ointment. [Accessed on 9th Nov 2022] https://allergan-web-cdn-prod.azureedge.net/allerganindia/allerganindia/media/allergan-india/products/zymar-ointment.pdf