Introduction About GRISURE TABLET

GRISURE TABLET contains Griseofulvin, which belongs to the group of medicines called Anti-fungal drugs. It is used to manage fungal infections of the skin, scalp, hair, groin, feet, or nails where topical therapy is not suitable or has failed to manage the condition.

Avoid drinking alcohol while receiving GRISURE TABLET management. Before taking GRISURE TABLET, inform your doctor if you have skin, liver, or kidney problems or porphyria (which results from an increase in certain chemicals related to red blood cell proteins).

GRISURE TABLET is not recommended for pregnant or breastfeeding women; therefore, consult your doctor before taking it. The most common side effects of taking GRISURE TABLET are headache, diarrhoea, nausea, vomiting, or stomach discomfort. Contact your doctor if any of the symptoms worsen.

Uses Of GRISURE TABLET

• Manage fungal infections of the skin, scalp, hair, groin, feet, and nails

How GRISURE TABLET Works

GRISURE TABLET inhibits the growth of fungi by binding to a part of the fungus causing the infection in the body. This stops the fungus from multiplying. It also manages fungus from spreading to new cells. These actions cause the fungal infection to shed completely.

How to use GRISURE TABLET

Take GRISURE TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

Side Effects Of GRISURE TABLET

How To Manage Side Effects

Nausea:

Get plenty of fresh air. Have ginger or peppermint tea. Eat foods having ginger (Ex. ginger biscuits). Eat smaller meals more frequently and slowly. Avoid strong-smelling, hot, fried or greasy food. Avoid large drinks with meals. Do not lie down immediately after eating. Avoid wearing clothes that are tight around your waist or tummy.

Vomiting:

Get adequate rest. Drink sufficient fluids to keep yourself hydrated. Have small sips if you feel sick. Eat little when you feel hungry. Do not take any medicine for vomiting without asking your doctor.

Headache:

Drink an ample amount of water. Get adequate rest. Try to be relaxed and stress-free. Ask your doctor before taking any medicine for headaches. Consult your doctor if your symptom gets worse or persist.

Diarrhoea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Consult your doctor if your symptom gets worse or persist.

Stomach pain:

Try to rest and relax. Eat and drink slowly or try to have smaller meals more frequently. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.

Warning & Precautions

Pregnancy

Do not take GRISURE TABLET if you are pregnant or think you might be pregnant. Consult your doctor immediately if you are taking GRISURE TABLET and you get pregnant.

Breastfeeding

GRISURE TABLET is not recommended for use in breastfeeding. Consult your doctor before taking it.

Driving and Using Machines

Do not drive or operate any machines after taking GRISURE TABLET as it may cause drowsiness, dizziness, confusion, and lack of coordination.

Alcohol

Avoid consumption of alcohol while taking GRISURE TABLET as it may make alcohol affect you more (nausea, vomiting, blush, irregular heartbeat, chest pain or abdominal pain).

Liver

GRISURE TABLET is not recommended in patients with severe liver disease. It should be used with caution if you have liver disease. Consult your doctor before taking it.

Allergy

Do not take GRISURE TABLET if you are allergic to Griseofulvin.

Interactions

A. Drug-Drug interactions:

Before taking GRISURE TABLET, inform your doctor if you are taking any of the following medicine:

• ciclosporin (used after organ transplantation to manage organ rejection)
• medicines used to thin your blood (Ex. warfarin, clopidogrel)
• methadone (used to manage addiction or pain)
• oral contraceptives (Ex. Ethinyl estradiol, norethindrone)
• medicines used to manage fits (Ex. phenobarbital, primidone)
• phenyl butazone (used to manage pain or inflammation)
• doxecalciferol (a vitamin D supplement)
• medicines for sedation, or relief of anxiety (Ex. alprazolam, diazepam)
• medicines used to manage infections (Ex. penicillin, cephalosporins)

Overdosage:

If you or anyone else accidentally take too much of GRISURE TABLET, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep GRISURE TABLET out of reach from children
• Do not store above 25°C

FAQs About GRISURE TABLET

Can I take GRISURE TABLET while planning for pregnancy?

GRISURE TABLET is not recommended for use during pregnancy as it may harm your baby. So, inform your doctor if you are pregnant, think you are pregnant or plan to get pregnant before taking it. For males, you should not father a child while taking GRISURE TABLET and for six months after you have stopped taking it, as it may damage your sperm. You and your partner should use contraceptives to manage pregnancy during this period.

Can GRISURE TABLET manage ringworm?

Yes. GRISURE TABLET is used to manage a fungal infection called ringworm. Your doctor will determine the correct dose and duration for you depending on your age, body weight, and disease condition.

Can I stop taking GRISURE TABLET?

Do not stop taking GRISURE TABLET without consulting your doctor. You must continue taking it, even if your infections get better. You should continue taking it for at least two weeks after the infection has cleared up. If you stop early, you have a high chance of getting affected again. If you have any doubts regarding GRISURE TABLET, consult your doctor.

Can GRISURE TABLET cause a photosensitivity reaction?

Yes. Your skin becomes more sensitive to sunlight or ultraviolet (UV) light when taking GRISURE TABLET. Avoid going to places with strong sunlight or artificial UV light, such as sunbeds. While going out, protect your skin by applying sunscreen protection cream with the approval of your doctor, which helps to manage sunburn allergy reactions. Inform your doctor if you have a previous history of skin problems before taking GRISURE TABLET.

What is GRISURE TABLET used for?

GRISURE TABLET contains griseofulvin, which belongs to the group of medicines called anti-fungal drugs. It is used to manage fungal infections of the skin, scalp, hair, hip, feet (athlete’s foot), and nails (ringworm) where topical therapy is not suitable or has failed to manage the infection.

Is GRISURE TABLET an antibiotic or antifungal?

GRISURE TABLET contains griseofulvin, which belongs to the group of medicines called anti-fungals. GRISURE TABLET inhibits the growth of fungi by binding to a part of the fungus causing the infection in the body. This stops the fungus from multiplying. It also manages fungi from spreading to new cells. These actions cause the fungal infection to shed completely.

Is GRISURE TABLET a steroid?

No, GRISURE TABLET is not a steroid; it’s an antifungal involved in the management of fungal infections of the skin, scalp, hair, hip, feet (athlete’s foot), and nails (ringworm), where topical therapy is not suitable or has failed to manage the condition.

Is GRISURE TABLET safe?

GRISURE TABLET is safe to use under a doctor’s supervision. GRISURE TABLET is approved for the management of fungal infections in both adults and children. There are many experimental studies supporting its use regarding safety and effectiveness.

Why is GRISURE TABLET taken with a high-fat meal?

GRISURE TABLET is better absorbed when taken together with high-fat meals such as cheese, avocados, yoghurt, and whole milk. It helps to clear the infection effectively by helping the body absorb the medication better and lessening the possibility of stomach problems.

Can I take GRISURE TABLET along with alcohol?

Alcoholic drinks and anything containing alcohol should be avoided while you are taking GRISURE TABLET. Alcohol reacts with GBNKEYWORD, causing unwanted reactions like nausea, vomiting, blushing, an irregular heartbeat, chest pain, and abdominal pain.

Can GRISURE TABLET cause liver damage?

Yes, in rare conditions GRISURE TABLET may affect the liver, and it is characterised by signs and symptoms such as lower back pain, pale urine, and yellowing of the skin and whites of the eyes (jaundice). Your doctor will assess any abnormalities in the liver through liver function tests during management with GRISURE TABLET.

Can GRISURE TABLET manage a yeast infection?

No, it is not intended to manage yeast infections. It is used to manage fungal infections of the skin, scalp, hair, hip, feet (athlete’s foot), and nails (ringworm) where topical therapy is not suitable or has failed to manage the condition. Kindly consult your doctor before using it.

What should I do if I forget to take GRISURE TABLET?

You should take GRISURE TABLET immediately when you remember. If it is time for your next dose, skip the missed dose and follow your regular dose schedule. Do not double the dose to make up for your missed dose.

References

1. KD Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 790-791.

2. Jazmine M. Olson; Todd Troxell. Griseofulvin. NCBI; PMC. National Library of Medicine, National Institute of Health. [Revised in April 2022] [Accessed on 30th April 2022] https://www.ncbi.nlm.nih.gov/books/NBK537323/

3. Novartis. Terbinafine Compared to Griseofulvin in Children with Tinea Capitis. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in February 2007] [Accessed on 30th April 2022] https://clinicaltrials.gov/ct2/show/NCT00117754

4. Brown & Brusk UK Ltd. Health Products Regulatory Authority (HPRA). [Revised in December 2020] [Accessed on 30th April 2022] https://www.hpra.ie/img/uploaded/swedocuments/7f6610e3-4310-445f-84d0-5a4a4131602f.pdf

5. Brown & Burk UK Limited. Electronic Medicines Compendium (EMC). [Revised in March 2012] [Accessed on 30th April 2022] https://www.medicines.org.uk/emc/files/pil.10746.pdf

6. GlaxoSmithKline Pharmaceuticals Limited. Griseofulvin. [Revised in July 2018] [Accessed on 30th April 2022] https://india-pharma.gsk.com/media/6382/grisovin-fp.pdf

7. Griseofulvin. Drugbank. [Accessed on 30th April 2022] https://go.drugbank.com/drugs/DB00400