Introduction About GRILINCTUS L ORAL SUSPENSION

GRILINCTUS L ORAL SUSPENSION contains Levocloperastine which belongs to the group of medicines called Antitussives agents. It is used for symptomatic management of non-productive cough associated with acute and chronic respiratory disorders. Do not consume alcohol while taking this medicine. GRILINCTUS L ORAL SUSPENSION is not recommended for use in patients with severe liver impairment, have excessive discharge of mucus, or limited mucociliary function.

Before using GRILINCTUS L ORAL SUSPENSION tell your doctor if you have hypertension, cardiovascular disease, uncontrolled diabetes mellitus, hyperthyroidism, or seizures GRILINCTUS L ORAL SUSPENSION is generally not recommended for use in pregnant or breastfeeding women. It is not recommended for use in children (early childhood). Consult your doctor if you experience nausea, headache, dizziness, exhaustion, or any other side effects.

Uses Of GRILINCTUS L ORAL SUSPENSION

• used for symptomatic management of non-productive cough associated with acute and chronic respiratory disorders

How GRILINCTUS L ORAL SUSPENSION Works

GRILINCTUS L ORAL SUSPENSION acts at the central nervous system (CNS) level by blocking both the central cough centre and peripheral receptors in the airway passage (trachea, lungs). Hence reducing the cough.

How to use GRILINCTUS L ORAL SUSPENSION

Use GRILINCTUS L ORAL SUSPENSION as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, disease condition and body weight.

Side Effects Of GRILINCTUS L ORAL SUSPENSION

How To Manage Side Effects

Nausea:

Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.

Dizziness:

When you start taking GRILINCTUS L ORAL SUSPENSION, you may feel faint or dizzy. This is caused by your blood pressure dropping. If this happens, resting or lying down for some time can help. Consult your doctor if symptoms don't improve. 

Headache:

Apply hot or cold-water bag on your head. Try to take rest in a quiet and dark room. Massage on scalp or head with mild pressure. Consult your doctor for advice.

Warning & Precautions

Pregnancy

GRILINCTUS L ORAL SUSPENSION is generally not recommended for use in pregnant women or women planning to have a baby as safety data has not been established yet. Consult your doctor before using it.

Breastfeeding

GRILINCTUS L ORAL SUSPENSION is generally not recommended for use in breastfeeding women as safety data has not been established yet. Consult your doctor before using it.

Alcohol

Do not consume alcohol while using GRILINCTUS L ORAL SUSPENSION.

Liver

GRILINCTUS L ORAL SUSPENSION is not recommended for use in patients with severe liver impairment. Consult your doctor before using it.

Allergy

Do not use GRILINCTUS L ORAL SUSPENSION if you are allergic to Levocloperastine or any of the other ingredients of this medicine.

Heart Disease

GRILINCTUS L ORAL SUSPENSION should be used with caution in patients with hypertension (high blood pressure) and cardiovascular diseases. Consult your doctor before using it.

Interactions

A. Drug – Drug Interactions:

Before using GRILINCTUS L ORAL SUSPENSION inform your doctor if you are taking any of the following medicine:

• antihistaminics (used to manage allergic conditions) Ex. hydroxyzine, diphenhydramine
• sedatives (used to manage anxiety, sleep issues) Ex. zolpidem, eszopiclone
• tranquilizers (used to reduce anxiety, fear, tension, agitation, and related states of mental disturbance) Ex. diazepam
• sympathomimetic amines (used to manage ischemic heart disease) Ex. epinephrine, norepinephrine
• antiserotonergic drugs (used to manage depression) Ex. ergots methysergide

Overdosage:

If you or anyone else accidentally use too much of GRILINCTUS L ORAL SUSPENSION, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep GRILINCTUS L ORAL SUSPENSION out of reach of children
• Store at room temperature

FAQs About GRILINCTUS L ORAL SUSPENSION

What GRILINCTUS L ORAL SUSPENSION used for?

It is used for symptomatic management of non-productive cough associated with acute and chronic respiratory disorders. Cough is a sudden expulsion of air through the large breathing passages that can help clear them of fluids, irritants, foreign particles, and microbes.

Can GRILINCTUS L ORAL SUSPENSION be used in pregnant women?

GRILINCTUS L ORAL SUSPENSION is generally not recommended for use in pregnant women or women planning to have a baby as safety data has not been established yet. Consult your doctor before using it.

Can GRILINCTUS L ORAL SUSPENSION be used in patients with heart problems?

GRILINCTUS L ORAL SUSPENSION should be used with caution in patients with hypertension (high blood pressure) and cardiovascular diseases. Consult your doctor before using it.

Can I stop using GRILINCTUS L ORAL SUSPENSION if I start to feel better?

You should not stop using GRILINCTUS L ORAL SUSPENSION even if your symptoms get better. Take GRILINCTUS L ORAL SUSPENSION for as long as your doctor has prescribed you for. If you wish to discontinue using it, ask for your doctor’s advice.

How does GRILINCTUS L ORAL SUSPENSION work?

GRILINCTUS L ORAL SUSPENSION acts at the central nervous system (CNS) level by blocking both the central cough centre and peripheral receptors in the airway passage (trachea, lungs). Hence reducing the cough.

References

1. Sean C Sweetman. Cough Suppressants, Expectorants, Mucolytics and Nasal Decongestants. Martindale-The Complete Drug Reference. Thirty Sixth Edition. 2009. Page - 1554.

2. P Aliprandi 1, C Castelli, S Bernorio, E Dell'Abate, M Carrara. Levocloperastine in the treatment of chronic non-productive cough: comparative efficacy versus standard antitussive agents. NIH: National Library of Medicine, National Center for Biotechnology Information. Pubmed.gov.2004. [Accessed on 8th August 2022] https://pubmed.ncbi.nlm.nih.gov/15553659/

3. Aliprandi P, Carrara M and Lorenzo Cima. Therapeutic Use of Levocloperastine as an Antitussive Agent: An Overview of Preclinical Data and Clinical Trials in Adults and Children. Research gate. April 2002. [Accessed on 8th August 2022] https://www.researchgate.net/publication/233505822_Therapeutic_Use_of_Levocloperastine_as_an_Antitussive_Agent_An_Overview_of_Preclinical_Data_and_Clinical_Trials_in_Adults_and_Children

4. Franco Indian Pharmaceuticals. Pvt. Ltd. Levocloperastine. [Accessed on 8th August 2022] http://www.francoindian.com/products/grilinctus-lsyrup.html

5. Zeventus Healthcare. Ltd. Levocloperastine. [Accessed on 8th August 2022] http://www.zuventus.co.in/patient_wise_products_selected.aspx?Medi_Id=158

6. Micro labs Ltd. Levocloperastine. [Accessed on 8th August 2022] https://www.microlabsltd.com/elibrary/node/2604