Glimisave MV 3.3 Tablet 10'S
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Introduction About GLIMISAVE MV 3.3 TABLET
Glimisave MV 3.3 Tablet is a prescription medication used to control blood sugar levels in individuals with Type 2 Diabetes Mellitus. It combines three antidiabetic agents Glimepiride, Metformin and Voglibose.
Glimisave MV 3.3 Tablet helps in controlling blood glucose levels, improves insulin sensitivity and manages type 2 diabetes.
Take this Glimisave MV 3.3 as directed by your doctor. Usually taken with meals to reduce gastrointestinal side effects. Do not skip or double doses to make up for the missed dose.
Glimisave MV 3.3 Tablet is not suitable for type 1 diabetes. Inform your doctor of any kidney, liver, or heart conditions. Always monitor blood sugar levels regularly.
Before taking Glimisave MV 3.3 Tablet, inform your doctor if you recently had trauma and/or have febrile infections, fever, uncontrolled diabetes, hypothyroidism (underactive thyroid), chronic intestinal disease, fever, or other kidney or liver problems.
The most common side effects of Glimisave MV 3.3 Tablet are hypoglycemia (low blood sugar, nausea and vomiting, stomach upset and flatulence or bloating. Consult your doctor if side effects persist or worsen.
Key Composition
- Glimepiride – 2 mg
- Metformin – 500 mg (Sustained Release)
- Voglibose – 0.3 mg
Uses Of GLIMISAVE MV 3.3 TABLET
- Used to control blood sugar levels in individuals with Type 2 Diabetes Mellitus
Benefits of GLIMISAVE MV 3.3 TABLET
1. Controlling blood glucose levels:
- Glimepiride stimulates the pancreas to release insulin
- Metformin reduces glucose production in the liver and improves glucose uptake
- Voglibose slows down carbohydrate absorption in the intestines
2. Improving insulin sensitivity:
- Metformin, one of the key ingredients, is known to increase insulin sensitivity, helping the body use insulin more effectively. This reduces insulin resistance which is a major issue in people with Type 2 diabetes
3. Managing Type 2 Diabetes:
- Targets different mechanisms of glucose imbalance
- Reduces the need for multiple separate medications
- Supports long-term glycemic control when used alongside diet and exercise
How GLIMISAVE MV 3.3 TABLET Works
Glimisave MV 3.3 Tablet contains a combination of three medicines namely, glimepiride, metformin, and voglibose. Glimepiride stimulates the pancreas to release more insulin, which helps lower blood sugar by allowing cells to take in glucose. Metformin decreases the amount of glucose produced by the liver and improves the sensitivity of muscle cells to insulin, allowing them to use glucose more effectively. Voglibose inhibits enzymes in the gut that break down carbohydrates into glucose, slowing down the absorption of sugar from food.
How to use GLIMISAVE MV 3.3 TABLET
Glimisave MV 3.3 dosage instructions:
- Take one Glimisave MV 3.3 tablet once daily, or as prescribed by your physician
- Each tablet contains a combination of Glimepiride (3 mg), Metformin (500 mg), and Voglibose (0.3 mg) in a sustained-release formulation
How to take Glimisave MV 3.3 Tablet:
- Swallow Glimisave MV 3.3 tablet whole with water
- Do not crush, chew, or break the tablet
When should I take it - before or after meals?
- Take Glimisave MV 3.3 tablet with or immediately after meals, usually with the first main meal of the day to minimize side effects like nausea or low blood sugar
.
What if I forgot to take GLIMISAVE MV 3.3 TABLET
- If you miss a dose, take it as soon as you remember
- If it is close to your next dose, skip the missed dose
- Do not double the dose to make up for a missed dose
Overdose
- An overdose may cause hypoglycemia (low blood sugar) symptoms like dizziness, sweating, shakiness, or confusion
- Seek immediate medical help if you suspect an overdose
Side Effects Of GLIMISAVE MV 3.3 TABLET
Common side effects of Glimisave MV 3.3 Tablet:
- hypoglycemia (low blood sugar)
- nausea and vomiting
- stomach upset
- flatulence or bloating
When to consult a doctor?
- severe hypoglycemia (very low blood sugar level)
- signs of lactic acidosis (lactic acid built up in the bloodstream) such as exhaustion or extreme fatigue, body weakness, diarrhea, and/or headache
How To Manage Side Effects
Bloating
- Limit or avoid beans, lentils, cauliflower, cabbage, broccoli, carbonated drinks, artificial sweeteners and high-fat or fried foods
- Peppermint tea, ginger tea, or fennel seed tea can help reduce bloating naturally
- Applying a warm heating pad to your abdomen can help relax muscles and ease bloating pain
Hypoglycemia
- Check your blood sugar by using a glucometer, if the blood sugar is below 70 mg/dL, it is hypoglycemia
- Eat 15 grams of fast-acting carbs like 3-4 glucose tablets, one tablespoon of sugar or honey, half glass of fruit juice like orange juice or regular (not diet) soft drink – half glass
- Recheck in 15 minutes, if still <70 mg/dL, repeat the steps, once normalized, eat a balanced meal to stabilize
Nausea And Vomiting
- Always take Glimisave MV 3.3 with or right after a meal (preferably a balanced one with carbohydrates and some fat)
- Instead of 2-3 large meals, have 4-5 smaller meals throughout the day
- Sip on clear fluids like water, coconut water, or ORS
- Do not lie down immediately after meals, wait at least 30 minutes to avoid reflux or worsened nausea
Stomach Upset
- Limit caffeine, alcohol, carbonated beverages, and foods high in fat or artificial sweeteners
- Hydration is key, especially if you are experiencing diarrhea or bloating
- Avoid spicy, oily, or processed foods while symptoms persist
Warning & Precautions
Pregnancy
Monitoring requiredGlimisave MV 3.3 is not recommended during pregnancy unless no safer alternatives are available and the benefits clearly outweigh the risks.
Breastfeeding
Monitoring requiredGlimisave MV 3.3 is not recommended during breastfeeding unless no safer alternatives are available and the benefits clearly outweigh the risks.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you experience impaired alertness or reactions (due to hypoglycemia) while taking Glimisave MV 3.3 Tablet.
Alcohol
Consult your doctorDo not consume alcohol while taking Glimisave MV 3.3 Tablet since it may reduce your blood sugar level.
Kidney
Consult your doctorGlimisave MV 3.3 Tablet is not recommended in patients with severe renal failure. It should be used with caution in patients with other kidney diseases.
Liver
Consult your doctorGlimisave MV 3.3 Tablet is not recommended for use in patients with severe liver disease. It should be used with caution in patients with other liver diseases.
Allergy
ContraindicatedDo not take if you are allergic to Glimepiride, Metformin, voglibose, other sulfonylureas/sulphonamides, and/or any other ingredients of this medicine.
Lungs
ContraindicatedGlimisave MV 3.3 Tablet is not recommended for use in patients with lung problems such as acute or chronic respiratory failure.
Heart Disease
ContraindicatedGlimisave MV 3.3 Tablet is not recommended in patients with heart problems such as acute or chronic cardiac failure or recent myocardial infarction.
Use In Pediatrics
ContraindicatedGlimisave MV 3.3 Tablet is not recommended for use in children and adolescents (aged below 18 years) since the safety and effectiveness of the medicine are not established.
Use In Geriatrics
Use with CautionGlimisave MV 3.3 Tablet should be used with caution in elderly patients (aged 65 years and above).
Other Warnings for GLIMISAVE MV 3.3 TABLET
Before taking Glimisave MV 3.3 Tablet, inform your doctor if you:
- recently had trauma
- had or scheduled for any surgery
- suffer from febrile infections, fever, and/or uncontrolled diabetes
- are undernourished and/or have irregular mealtimes or skipped meals
- suffer from an imbalance between physical exertion and carbohydrate intake
- have hypothyroidism (underactive thyroid)
- have a history of laparotomy (a surgical incision done into the abdominal cavity for diagnosing a condition) and/or ileus (interrupted movement of the intestines)
- suffer from chronic intestinal disease (accompanied by disturbances in digestion and absorption)
- suffer from fever
Who should not take [GBNKEYWORD
Glimisave MV 3.3 Tablet is not recommended for use if you:
- suffer from any acute type of metabolic acidosis (the buildup of excess acid in the body), such as lactic acidosis, diabetic ketoacidosis, and/or diabetic precoma
- suffer from acute conditions such as dehydration, severe infection, and shock
- have severe ketosis
- had severe infections before or after the operation
- had severe trauma
- have gastrointestinal obstruction
Diet and Lifestyle Advice
Foods to eat/avoid while taking Glimisave MV:
| Food type | Why it is good |
| Whole Grains (oats, brown rice, quinoa) | Low glycemic index - helps maintain steady blood sugar |
| High-Fiber Veggies (spinach, broccoli, carrots) | Aids digestion and supports blood sugar control |
| Lean proteins (chicken, eggs, tofu, fish) | Keeps you full and helps to manage blood sugar spikes |
| Low-Fat Dairy (curd, milk, paneer) | Provides protein and calcium without added sugars |
| Nuts & Seeds (almonds, chia, flaxseeds) | Healthy fats that support heart and metabolic health |
| Bitter Foods (bitter gourd, fenugreek) | May help lower blood sugar naturally |
| Hydrating Fluids (water, buttermilk, herbal teas) | Manages dehydration and supports kidney function |
Foods to avoid while taking Glimisave MV:
| Avoid these | Why they are harmful |
| Sugary foods (sweets, soft drinks, desserts) | Cause blood sugar spikes, may interfere with medication |
| Refined Carbs (white bread, pasta, maida-based snacks) | High glycemic index, rapidly raise blood glucose |
| Fried & Fatty Foods | Can worsen bloating and GI discomfort (a side effect of Metformin and Voglibose) |
| Processed foods (packaged snacks, fast food) | Often contain hidden sugars and trans fats |
| Caffeinated or Fizzy Drinks | May worsen stomach upset or bloating |
Exercise tips to improve medication effectiveness:
- walking - 30 minutes, 5 days a week
- strength training - 2-3 times a week
- cycling - 30–45 minutes, 3-5 times a week
- swimming (gentle & effective for joints) - 30–45 minutes, 3 times a week
- high-intensity interval training (HIIT) - 15–20 minutes, 3 times a week
How to balance Glimisave with my daily routine:
- Take Glimisave MV 3.3 once daily, just before or with the first main meal of the day (usually breakfast)
- Eat regular, balanced meals at the same time each day
- Include protein + fiber in each meal to maintain glucose stability
- Incorporate light to moderate physical activity
- Monitor your fasting and postprandial blood sugar regularly, especially during the first few weeks.
Drug - Drug interaction
Glimisave MV 3.3 interactions with other medications?
1. Drugs that may increase the risk of hypoglycemia (low blood sugar):
| Drug class | Examples |
| Beta-blockers | Atenolol, Metoprolol (also masks symptoms of low blood sugar) |
| ACE Inhibitors | Enalapril, Ramipril |
| Sulfonamides | Sulfamethoxazole |
| Quinolone Antibiotics | Ciprofloxacin, Levofloxacin |
| NSAIDs | Ibuprofen, Naproxen |
| Other Antidiabetic Agents | Insulin, Gliclazide, Sitagliptin |
2. Drugs that may reduce the effectiveness of Glimisave MV:
| Drug class | Examples |
| Corticosteroids | Prednisolone, Dexamethasone |
| Thiazide Diuretics | Hydrochlorothiazide |
| Oral Contraceptives | Estrogen-based pills |
| Thyroid Medications | Levothyroxine |
| Sympathomimetics | Epinephrine, Salbutamol |
3. Drugs that increase the risk of Lactic acidosis (a rare but serious side effect of Metformin):
| Drug class | Examples |
| Contrast agents for imaging | Iodinated dyes |
| Nephrotoxic medications | Aminoglycosides, high-dose NSAIDs |
| Cimetidine | (slows metformin clearance) |
Synopsis
| Drug | : | Glimepiride, Metformin, Voglibose |
| Pharmacological Category | : | Antidiabetic Agents |
| Therapeutic Indication | : | Type II diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
Compare Glimisave MV 3.3 with other antidiabetic medications?
| Medication | Composition | Mechanism | Common Side Effects | Ideal For |
| Glimisave MV 3.3 | Glimepiride + Metformin + Voglibose | Boosts insulin, lowers liver glucose, delays carb absorption | Hypoglycemia, bloating, nausea | Patients needing strong glucose control |
| Janumet | Sitagliptin + Metformin | Enhances insulin after meals, reduces sugar production | Headache, mild stomach upset | Mild to moderate diabetes |
| Glycomet GP 2 | Glimepiride + Metformin | Boosts insulin & lowers sugar production | Hypoglycemia, nausea | Moderate diabetes, cost-effective |
| Triohale-M | Glimepiride + Metformin + Pioglitazone | Improves insulin sensitivity | Weight gain, edema, risk of fractures | Insulin-resistant patients |
| Voglibose alone | Voglibose | Slows sugar absorption post meals | Flatulence, diarrhea | Patients with postprandial sugar spikes |
Alternatives for Glimisave MV 3.3 or You may also like:
Understanding Type 2 Diabetes
Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder that affects the way the body processes blood sugar (glucose). It is the most common form of diabetes and can often go undiagnosed until symptoms become severe.
Causes of Type 2 Diabetes:
| Contributing factor | Description |
| Insulin resistance | Cells do not respond properly to insulin |
| Genetics | Family history increases risk |
| Obesity | Especially abdominal fat contributes to insulin resistance |
| Inactivity | Lack of exercise slows metabolism |
| Unhealthy diet | High sugar, processed food intake raises risk |
Symptoms to watch out for
- Frequent urination
- Excessive thirst or hunger
- Fatigue
- Blurred vision
- Slow-healing wounds
- Tingling or numbness in hands/feet
- Unexplained weight loss
- Early diagnosis and intervention are key to avoiding complications
Management strategies
| Management area | Key practices |
| Medication | Tablets like Glimisave MV 3.3 regulate blood sugar levels |
| Diet | Balanced meals low in carbs and sugar, high in fiber |
| Exercise | Aim for 30 mins of activity most days |
| Blood Sugar Monitoring | Track regularly to adjust treatment as needed |
| Regular Checkups | Monitor HbA1c, cholesterol, kidney function, and more |
FAQs About GLIMISAVE MV 3.3 TABLET
Q: What is Glimisave MV 3.3 used for?
A: Glimisave MV 3.3 is used in adults to manage type 2 diabetes mellitus when diet, exercise, and single-agent or second-line therapy with two drugs are insufficient to adequately control blood sugar levels.
Q: How does Glimisave MV 3.3 work?
A: Glimisave MV 3.3 works as a combination by lowering fasting and post-meal blood glucose, improving the body’s response to insulin and controlling long-term complications of diabetes.
Q: Can Glimisave MV 3.3 be taken with other diabetes medications?
A: In most cases, Glimisave MV 3.3 is not combined with other oral diabetes medications, as it already contains three active agents Glimepiride (sulfonylurea), Metformin (biguanide) and Voglibose (alpha-glucosidase inhibitor). Since this combination targets blood sugar from multiple angles, adding more oral medications increases the risk of hypoglycemia (low blood sugar) and gastrointestinal side effects.
Q: Is Glimisave MV 3.3 suitable for elderly patients?
A: Glimisave MV 3.3 can be prescribed to elderly patients, but it should be used with caution under medical supervision.
Q: How long does it take for Glimisave MV 3.3 to show effects?
A: The time it takes for Glimisave MV 3.3 to show noticeable effects can vary depending on individual factors such as the severity of diabetes, current blood sugar levels, overall health, and adherence to lifestyle changes.
Q: Can I take Glimisave MV with insulin?
A: Yes, Only under the doctor supervision. Taking both can increase the risk of hypoglycemia.
Q: What should I do if I miss a dose?
A:Take it as soon as you remember. If it is near the time of the next dose, skip the missed one. Do not double dose to make up for the missed dose.
Q: What are the side-effects of Glimisave MV?
A: The most common side-effects of Glimisave MV are hypoglycemia (low blood sugar, nausea and vomiting, stomach upset and flatulence or bloating.
Q: Is Glimisave MV 3.3 safe during pregnancy?
A: No, Glimisave MV 3.3 is generally not recommended during pregnancy. The combination of Glimepiride, Metformin, and Voglibose has not been adequately studied in pregnant women, and there may be potential risks for both the mother and the fetus.
Q: Can I drink alcohol while taking Glimisave MV 3.3?
A: It is generally not recommended to drink alcohol while taking Glimisave MV 3.3, as alcohol can interact with the medications and increase the risk of certain side effects, especially hypoglycemia (low blood sugar).
Q: How soon will I feel a difference in my sugar levels?
A: The time it takes to notice a difference in your blood sugar levels after starting Glimisave MV 3.3 can vary, but you may start seeing effects within 1 to 2 weeks. However, the full impact on your blood sugar may take a bit longer.
Q: What should I monitor while on this medication?
A: While taking Glimisave MV 3.3, it’s important to regularly monitor, blood sugar levels, A1ClLevels, kidney function and signs of hypoglycemia, gastrointestinal symptoms and liver function.
Q: What to do if I feel dizzy or have stomach upset?
A: If you experience dizziness or stomach upset while taking Glimisave MV 3.3, it is important to follow certain steps to manage these symptoms and ensure your safety.
Q: Should I stop if I feel hypoglycemic?
A: If you feel hypoglycemic (low blood sugar) while taking Glimisave MV 3.3, do not stop the medication immediately. Hypoglycemia is a potential side effect, but stopping your medication without medical advice may lead to poor blood sugar control in the long run.
Q: What if my blood sugar stays high even with this medication?
A: If your blood sugar remains high despite taking Glimisave MV 3.3, it could indicate that the medication does not adequately controlling your blood sugar levels or that other factors are influencing your glucose control.
References
1. KD Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of Medical Pharmacology. Seventh Edition. 2019. Page – 270, 275, 277.
2. Kalra S, Das AK, Priya G, Ghosh S, Mehrotra RN, Das S, Shah P, Bajaj S, Deshmukh V, Sanyal D, Chandrasekaran S, Khandelwal D, Joshi A, Nair T, Eliana F, Permana H, Fariduddin MD, Shrestha PK, Shrestha D, Kahandawa S, Sumanathilaka M, Shaheed A, Rahim AA, Orabi A, Al-Ani A, Hussein W, Kumar D, Shaikh K. Fixed-dose combination in management of type 2 diabetes mellitus. NIH National Library of Medicine. National center for biotechnology information. PMC PubMed Central. [Revised in November 2020] [Accessed on 21st April 2025] 
3. Windlas Biotech Private Limited. Amaryl MV 1mg, Amaryl MV 2mg. [Revised in March 2021] [ [Accessed on 21st April 2025]
4. Primus Remedies Pvt. Ltd. Voglow GM1 Fort. [Accessed on 21st April 2025]
5. Eris Lifesciences. Glimisave MV 1.3 F, Glimisave MV 2 forte, Glimisave MV 3.3, Glimisave MV 3.3 F. [Accessed on 21st April 2025]
6. Leeford Healthcare Ltd. VOGLIMET-GM FORTE. [Accessed on 21st April 2025]
7. Ikon Remedies Pvt. Ltd. Voglicon-GM Tablets. [Accessed on 21st April 2025]
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