GLIMISAVE M1X Tablet 30's

30 Tablet(s) in a Strip Mkt: Eris Lifesciences Ltd Country of Origin: India
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Introduction About GLIMISAVE M1X TABLET

GLIMISAVE M1X TABLET is used for the effective management of type 2 diabetes. It helps control blood sugar levels and is prescribed to improve insulin sensitivity. Each pack contains 15 tablets, providing a month-long supply for most users.

GLIMISAVE M1X TABLET should be taken with food. For the best results, take it consistently at the same time each day. Your doctor will determine the appropriate dosage for you, which may adjust over time based on your blood sugar levels.

Continue taking this medication, even if you feel fine or your blood sugar is under control. Stopping it without your doctor's approval could cause your blood sugar to increase once again. Keep in mind that this medication is just one part of your overall management plan, which should also include a healthy diet, regular exercise, and weight management as recommended by your doctor. Your lifestyle plays a key role in managing diabetes.

The most common side effects of this medication include headache, stomach upset, dizziness and low blood sugar levels (hypoglycemia), taste disturbance, diarrhea, stomach pain, loss of appetite and upper respiratory tract infection. Be aware of the signs of low blood sugar, like sweating, dizziness, headaches, and shaking, and know how to handle them. To prevent this, eat regular meals and keep a quick source of glucose, like sugary snacks or fruit juice, on hand. Avoid drinking alcohol, as it can raise the risk of low blood sugar. Some individuals might experience weight gain while taking this medication.

This medication should be avoided if you have type 1 diabetes mellitus, diabetic ketoacidosis (high acid levels in the blood), or severe kidney or liver disease. Before using this medicine, inform your doctor if you have a history of heart disease, as it may not be appropriate for you. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor may recommend regular blood sugar monitoring, as well as tests to check your blood cell counts and liver function.

Uses Of GLIMISAVE M1X TABLET

  • Type 2 diabetes mellitus

Benefits of GLIMISAVE M1X TABLET

  • Helps lower blood sugar levels
  • Improves insulin sensitivity and pancreatic function
  • Reduces the risk of complications related to diabetes
  • Effective in managing type 2 diabetes when used with a proper diet and exercise plan

How GLIMISAVE M1X TABLET Works

GLIMISAVE M1X TABLET combines two active ingredients: Glimepiride and Metformin. Glimepiride stimulates the pancreas to release insulin, helping reduce blood sugar levels. Metformin improves the body's sensitivity to insulin and decreases glucose production in the liver thus helping to decrease blood sugar levels.

How to use GLIMISAVE M1X TABLET

How to Take GLIMISAVE M1X TABLET?

  • Typically, take once or twice daily with meal or as advised by your doctor
  • Swallow the tablet whole with a glass of water. Do not crush or chew the medication.
  • It is recommended to take GLIMISAVE M1X TABLETt with food to reduce the risk of stomach upset (such as nausea)
  • Try to take the tablet at the same time each day to help remember and ensure consistency.

Dosage Instructions for Adults and Children:

For Adults:

  • Typically, take once daily with food to reduce gastrointestinal discomfort.

For Children:

  • Not recommended for children under 18 years of age. The safety and efficacy for pediatric use have not been established.

What if I forgot to take GLIMISAVE M1X TABLET

Missed Dosage instructions for GLIMISAVE M1X TABLET:

  • Take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and go back to your regular schedule
  • Do not take a double dose to make up for the missed one.

Overdose

Overdosage of GLIMISAVE M1X TABLET:

If you or anyone else accidentally take too much of GLIMISAVE M1X TABLET, consult and inform your doctor immediately or visit the nearby hospital. Symptoms of overdose are lactic Acidosis symptoms such as weakness, fatigue, difficulty breathing, dizziness, muscle pain or cramping and slow or irregular heartbeat, hypoglycemia (low blood sugar) symptoms such as sweating, tremors, dizziness or lightheadedness, confusion, rapid heartbeat, seizures, and loss of consciousness.

Side Effects Of GLIMISAVE M1X TABLET

Like all medicines, GLIMISAVE M1X TABLET may cause certain side effects in some individuals, although not everybody gets them.

The most common side effects of taking GLIMISAVE M1X TABLET are:

  • low blood sugar (hypoglycemia)
  • stomach discomfort
  • nausea
  • dizziness
  • vomiting
  • headache
  • taste disturbance
  • diarrhea
  • stomach pain
  • loss of appetite
  • upper respiratory infections

When to consult your doctor?

  • Severe Hypoglycemia (low Blood Sugar) symptoms such as sweating, shaking, confusion, dizziness, rapid heartbeat, blurry vision, headache, loss of consciousness.
  • Lactic Acidosis symptoms such as muscle pain or weakness, difficulty breathing, stomach discomfort, dizziness, or feeling cold.
  • Allergic Reactions symptoms such as rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
  • Unexplained Weight Loss
  • Gastrointestinal problems such as nausea, vomiting, diarrhea, severe dehydration
  • Liver problems symptoms such as yellowing of the Skin or Eyes (Jaundice)
  • Breathing Difficulties or Fatigue

How To Manage Side Effects

Diarrhea

  • Drink Fluids: Drink clear fluids such as water, broths, and oral rehydration solutions (ORS).
  • Electrolytes: If you are losing a lot of fluids (for example, from frequent diarrhea), consider drinking an electrolyte solution to help replenish lost minerals like potassium and sodium.
  • BRAT Diet: Try to take Bananas, Rice (white rice), Apple sauce and Toast (plain, without butter) to control diarrhoea management.
  • Avoid Certain Foods: While recovering avoid the following food items such as fatty, greasy, or fried foods, spicy foods, dairy products (especially if you have a temporary lactose intolerance), caffeinated drinks and alcohol and artificial sweeteners like sorbitol.
  • Over-the-Counter Medications: You can take over-the-counter anti-diarrheal medications such as loperamide, Bismuth subsalicylate if appropriate for you. Follow the recommended dosage.

Dizziness Or Drowsiness

  • Sit or Lie Down: If you feel dizzy, sit down or lie down immediately to prevent falling. Keep your head still and close your eyes if needed.
  • Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
  • Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
  • Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
  • Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.

Headache

  • Rest in a Quiet, Dark Room: Find a calm, quiet space away from bright lights and loud noises. Lie down and close your eyes.
  • Hydrate: Dehydration can contribute to headaches, so drink plenty of water.
  • Apply a Cold or Warm Compress: A cold pack on your forehead may reduce pain, or a warm compress on your neck or shoulders can relieve tension.
  • Over-the-Counter Pain Relief: You can take over-the-counter pain relievers like acetaminophen or ibuprofen if appropriate for you. Follow the recommended dosage.
  • Practice Relaxation Techniques: Deep breathing exercises, meditation, or gentle stretching can help reduce stress and alleviate headache symptoms.

Hypoglycemia

  • Act Quickly: If you notice symptoms of hypoglycemia, you need to raise your blood sugar immediately.
  • Consume Fast-Acting Carbohydrates: Eat or drink something containing 15-20 grams of fast-acting carbs (e.g., glucose tablets, fruit juice, regular soda). Avoid foods with fat, as they can slow down the absorption of sugar.
  • Recheck in 15 Minutes: After consuming carbs, check your blood sugar. If it is still low, repeat the process.
  • Avoid Overeating: Once blood sugar is normalized, avoid overconsumption of food, which can cause a rebound effect.

Nausea And Vomiting

  • Eat Small, Frequent Meals: Avoid heavy or greasy foods. Opt for bland foods like crackers, toast, or bananas.
  • Stay Hydrated: Sip on clear fluids like water, ginger tea, or electrolyte drinks, Avoid caffeinated and carbonated beverages.
  • Ginger: Ginger is a natural remedy for nausea. Try ginger tea, ginger candies, or ginger ale (ensure it contains real ginger).
  • Avoid Strong Odors: Minimize exposure to smells that might trigger nausea, such as perfumes or cooking odors.

Warning & Precautions

Pregnancy

Contraindicated

GLIMISAVE M1X TABLET is not recommended for use during pregnancy due to limited human studies and evidence from animal research indicating potential harm to the developing baby. Your doctor will assess the benefits and possible risks before prescribing it to you. Please consult your doctor for further guidance

Breastfeeding

Contraindicated

GLIMISAVE M1X TABLET is not recommended for use during breastfeeding. Limited human data indicates that the medication may transfer into breast milk and potentially harm the baby. It is important to consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Avoid driving or operating machinery if you experience low or high blood sugar levels symptoms include dizziness, fatigue, shaking, or trembling. Additionally, refrain from these activities if you have vision problems caused by changes in your blood sugar levels.

Alcohol

Consult your doctor

It is advisable to avoid alcohol consumption while taking GLIMISAVE M1X TABLET, as it may either enhance or reduce the blood sugar-lowering effect and increase the risk of lactic acidosis.

Kidney

Consult your doctor

GLIMISAVE M1X TABLET should be used with caution in patients with kidney disease. Dosage adjustment and careful monitoring are required in such patients. GLIMISAVE M1X TABLET is not recommended for individuals with severe kidney disease. Regular monitoring of kidney function is recommended while taking this medication. Please consult your doctor before taking it.

Liver

Consult your doctor

GLIMISAVE M1X TABLET should be used with caution in patients with liver disease. Dose adjustment of GLIMISAVE M1X TABLET may be needed. GLIMISAVE M1X TABLET is generally started with low dose in patients with mild to moderate liver disease and is not recommended for use in patients with severe liver disease. Therefore, inform your doctor if you have any pre-existing liver diseases as a precaution. Please consult your doctor before taking it.

Allergy

Contraindicated

Do not take this medication if you are allergic to metformin or glimepiride, and/or any other ingredients of this medicine.

Heart Disease

Contraindicated

GLIMISAVE M1X TABLET is not recommended for use in patients with acute heart problems or recently had a heart attack or have severe circulatory problems or breathing difficulties (signs of heart failure). Please consult your doctor before taking it.

Use In Pediatrics

Contraindicated

GLIMISAVE M1X TABLET is not recommended for use in children and adolescents (under 18 years of age). Consult your pediatrician before giving it.

Use In Geriatrics

Consult your doctor

GLIMISAVE M1X TABLET should be used with caution in elderly patients. Dosage adjustment and careful monitoring are required in such patients. Consult your doctor before taking it.

Other Warnings for GLIMISAVE M1X TABLET

Before taking GLIMISAVE M1X TABLET, inform your doctor if you:

  • are recovering from injury, operation, infections with fever, or from other forms of stress
  • have glucose-6-phosphate dehydrogenase (G6PD) deficiency
  • have various factors which could increase the risk of low blood sugar levels (such as undernourishment, irregular mealtime, missed or delayed meal or period of fasting, change in diet, hormone-induced disorders)

Who should not take [GBNKEYWORD

GLIMISAVE M1X TABLET is generally not recommended for use if you have:

  • type 1 diabetes mellitus
  • diabetic ketoacidosis
  • uncontrolled diabetes or ketoacidosis
  • dehydration
  • severe infection

Safety Advice

  • Typically, take once or twice daily with meal or as advised by your doctor
  • Swallow the tablet whole with a glass of water. Do not crush or chew the medication.
  • It is recommended to take GLIMISAVE M1X TABLET with food to reduce the risk of stomach upset (such as nausea)
  • Try to take the tablet at the same time each day to help remember and ensure consistency.
  • Follow the prescribed diet and exercise plan along with taking this medication for best results.
  • Monitor your blood sugar levels regularly while taking this medicine.
  • Avoid alcohol while taking this medication, as it can increase the risk of hypoglycemia or lactic acidosis.
  • Your doctor might regularly monitor your kidney and liver function.
  • Let your doctor know if you have kidney disease or any history of kidney problems, liver disease or a history of liver problems or heart problems or severe infection or dehydration.
  • Let your doctor know If you are pregnant or planning to become pregnant or breastfeeding women.
  • Do not suddenly stop taking the medication without consulting your doctor, as this can lead to uncontrolled blood sugar levels.
  • If you experience nausea, vomiting, diarrhea, stomach upset, and dizziness, unusual tiredness, muscle pain, difficulty breathing, or a slow heart rate, seek medical attention immediately.
  • GLIMISAVE M1X TABLET can interact with various medications, including diuretics, corticosteroids, thyroid medications, and other drugs (prescription or over-the-counter) you are taking.

Diet and Lifestyle Advice

Area

Recommendations

Balanced Meals

Include a variety of whole foods: Focus on vegetables, lean proteins, whole grains, healthy fats, and fruits.

 

Choose low glycemic index (GI) foods: Foods like whole grains, legumes, non-starchy vegetables, and fruits like berries.

 

Limit refined carbs and sugar: Avoid sugary drinks, pastries, and white bread.

 

Incorporate fiber-rich foods: Oats, beans, lentils, and vegetables help regulate blood sugar levels.

 

Control carbohydrate intake: Spread carbs evenly throughout the day to avoid blood sugar spikes.

 

Healthy fats: Include sources of unsaturated fats such as avocado, olive oil, and nuts.

Portion Control

Measure portion sizes: Use measuring cups, food scales, or visual cues (e.g., palm for protein, fist for veggies).

 

Mindful eating: Eat slowly and pay attention to hunger cues to avoid overeating.

 

Smaller, more frequent meals: Opt for 5-6 smaller meals rather than 3 large meals to help regulate blood sugar.

 

Limit high-calorie, low-nutrient foods: Such as chips, sugary snacks, and fried foods.

Lifestyle Changes

Monitor blood sugar regularly: Track blood sugar levels to understand how foods, exercise, and stress impact it.

 

Maintain a healthy weight: Aim for gradual weight loss (5-10% of body weight) to improve insulin sensitivity.

 

Manage stress: Stress increases blood sugar levels; practice mindfulness, yoga, or relaxation techniques.

 

Get adequate sleep: Aim for 7-9 hours of sleep to help regulate blood sugar and insulin levels.

 

Stay hydrated: Drink plenty of water to help flush excess sugar through urine.

Safe Exercises

Aerobic exercise: Aim for 150 minutes per week (e.g., brisk walking, swimming, cycling).

 

Strength training: Include muscle-strengthening exercises at least 2 days a week (e.g., resistance bands, weights).

 

Flexibility exercises: Stretching, yoga, and Pilates can improve flexibility and help reduce stress.

 

Low-impact activities: If you have joint issues, try walking, water aerobics, or cycling to minimize strain.

 

Monitor blood sugar during exercise: Check blood sugar before and after exercise, especially if on insulin.

Drug - Drug interaction

Inform your physician if you are taking any of the following medicine before taking GLIMISAVE M1X TABLET:

1. Other Antidiabetic Medications:

Interaction: Using other oral antidiabetic drugs (e.g., insulin, other sulfonylureas, thiazolidinediones, DPP-4 inhibitors, GLP-1 agonists) alongside GLIMISAVE M1X TABLETcan increase the risk of hypoglycemia (low blood sugar).

Effect: Severe hypoglycemia can occur, which may result in symptoms like confusion, sweating, dizziness, and, if untreated, loss of consciousness or seizures.

Management: Regular monitoring of blood sugar levels is essential. Adjusting the dose of GLIMISAVE M1X TABLET or the other antidiabetic drug might be necessary to prevent hypoglycemia. Always consult your doctor for proper guidance.

2. Corticosteroids (e.g., Prednisone):

Interaction: Corticosteroids can increase blood sugar levels by impairing insulin action. This can counteract the blood sugar-lowering effects of GLIMISAVE M1X TABLET

Effect: Elevated blood glucose levels and potential loss of glycemic control, leading to hyperglycemia.

Management: Close monitoring of blood sugar is required. Adjustments to the dose of GLIMISAVE M1X TABLET may be necessary. In some cases, insulin therapy might be considered during corticosteroid use.

3. Beta-blockers (e.g., Metoprolol, Atenolol):

Interaction: Beta-blockers can mask the symptoms of hypoglycemia (e.g., tremors, palpitations), making it harder to detect low blood sugar.

Effect: Difficulty in recognizing the signs of hypoglycemia, which could lead to more severe cases of low blood sugar.

Management: Blood sugar levels should be monitored more frequently. Patients should be educated about hypoglycemia and its silent symptoms. A dose adjustment of GLIMISAVE M1X TABLET might be needed based on blood sugar readings.

4. Angiotensin-converting enzyme (ACE) Inhibitors (e.g., Lisinopril):

Interaction: ACE inhibitors can lower blood pressure and have a potential to increase the glucose-lowering effect of GLIMISAVE M1X TABLET, leading to a higher risk of hypoglycemia.

Effect: Increased risk of hypoglycemia due to enhanced effect of GLIMISAVE M1X TABLET.

Management: Blood sugar monitoring should be done more frequently. Your doctor may adjust the dose of GLIMISAVE M1X TABLET  to avoid hypoglycemia.

5. Diuretics (e.g., Hydrochlorothiazide):

Interaction: Thiazide diuretics can increase blood sugar levels and decrease the effectiveness of GLIMISAVE M1X TABLET by causing insulin resistance.

Effect: Increased risk of hyperglycemia, which may reduce the control of blood sugar levels.

Management: Regular monitoring of blood glucose levels is essential, and dose adjustments to GLIMISAVE M1X TABLET may be required. Alternative antihypertensive medications or diuretics with less effect on blood sugar may be considered.

6. Phenothiazines (e.g., Chlorpromazine):

Interaction: These antipsychotic medications may raise blood sugar levels by inhibiting insulin secretion, potentially interfering with the effectiveness of GLIMISAVE M1X TABLET.

Effect: Hyperglycemia due to reduced insulin secretion and increased insulin resistance.

Management: Close monitoring of blood sugar levels is essential, and GLIMISAVE M1X TABLET dosage adjustments may be necessary to maintain optimal blood glucose control.

7. Thyroid Medications (e.g., Levothyroxine):

Interaction: Thyroid hormone replacement therapy can affect blood sugar levels, either by improving or worsening glycemic control, depending on the dose and individual response.

Effect: Potential for either hypoglycemia or hyperglycemia, depending on thyroid hormone levels and GLIMISAVE M1X TABLET efficacy.

Management: Monitoring of blood glucose and thyroid function tests are essential. Dose adjustments may be needed based on thyroid hormone levels and glucose control.

8. Anticoagulants (e.g., Warfarin):

Interaction: GLIMISAVE M1X TABLET and warfarin may both affect the liver and increase the risk of bleeding.

Effect: Risk of bleeding complications, especially if hypoglycemia occurs along with anticoagulant use.

Management: Close monitoring of blood glucose and coagulation parameters is necessary. Regular INR testing should be conducted when both medications are used together.

9. Cimetidine (Antacid):

Interaction: Cimetidine can increase the levels of metformin in the blood by inhibiting its clearance from the kidneys. This may increase the risk of lactic acidosis, a rare but serious side effect of metformin.

Effect: Elevated risk of lactic acidosis, which can be life-threatening and may cause symptoms like abdominal discomfort, breathing difficulties, and muscle cramps.

Management: If cimetidine is needed, dosage adjustments may be required, and careful monitoring for signs of lactic acidosis should be done.

10. Alcohol:

Interaction: Alcohol can intensify the blood sugar-lowering effect of GLIMISAVE M1X TABLET, leading to hypoglycemia, especially when consumed on an empty stomach.

Effect: The risk of hypoglycemia increases, particularly after drinking alcohol, as the liver prioritizes metabolizing alcohol over maintaining blood sugar levels.

Management: Limit alcohol consumption and avoid drinking on an empty stomach. Regular monitoring of blood glucose is necessary, and patients should be educated about the risks of drinking while on GLIMISAVE M1X TABLET.

11. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) (e.g., Diclofenac):

Interaction: Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that can affect renal function, which may enhance the risk of lactic acidosis, a rare but serious side effect of Metformin. This can be particularly concerning if there is renal impairment. NSAIDs like Diclofenac may also interfere with the blood glucose-lowering effect of Gliclazide, potentially requiring closer monitoring of blood glucose levels.

Effect: NSAIDs may decrease renal function and may lead to increased blood sugar levels, potentially interfering with GLIMISAVE M1X TABLETs effectiveness in controlling blood sugar.

Management: Close monitoring of kidney function is recommended, especially in individuals with pre-existing renal disease or those who are dehydrated. Blood glucose levels should be closely monitored.

12. Antifungal Medications (e.g., Fluconazole):

Interaction: Fluconazole can increase the blood levels of Gliclazide due to inhibition of the liver enzyme CYP2C9 that metabolizes Gliclazide. This can lead to an increased risk of hypoglycemia (low blood sugar). Fluconazole may also slightly impair the renal clearance of Metformin, although this interaction is less significant compared to Gliclazide.

Effect: The main concern is an increased risk of hypoglycemia because Fluconazole can potentiate the effect of Gliclazide.

Management: Careful blood glucose monitoring is important. If necessary, the dose of Gliclazide should be adjusted, and caution should be taken when starting or discontinuing Fluconazole.

13. Antibiotic (e.g., Rifampicin):

Interaction: Rifampicin is a potent enzyme inducer and may increase the metabolism of Gliclazide, potentially leading to reduced blood glucose-lowering effectiveness. This can cause inadequate blood sugar control. Rifampicin can also affect the clearance of Metformin, though this interaction is typically less pronounced than with Gliclazide.

Effect: The primary concern with Rifampicin is that it may reduce the effectiveness of Gliclazide, leading to increased blood glucose levels.

Management: Patients may need closer monitoring of blood glucose levels and potential adjustment of Gliclazide doses when Rifampicin is started. If possible, alternative antibiotics may be considered for better glucose control.

Synopsis

Drug :   Glimepiride, Metformin
Pharmacological Category :   Sulfonylureas, Biguanides
Therapeutic Indication :   Type II diabetes mellitus      
Dosage Forms :   Tablet

More Information

What are the key benefits of GLIMISAVE M1X TABLET, particularly in terms of reducing blood sugar, reducing diabetes complications, and improving insulin sensitivity?

  • Helps Reduce Blood Sugar Levels: GLIMISAVE M1X TABLET contains a combination of Glimepiride and Metformin, which work together to lower blood glucose levels effectively. This helps individuals with type 2 diabetes maintain better control over their blood sugar.
  • Improves Insulin Sensitivity: By improving the body’s response to insulin, GLIMISAVE M1X TABLET helps enhance the effectiveness of the insulin already produced, which is crucial for better glucose control.
  • Reduce Diabetes Complications: Consistent use of GLIMISAVE M1X TABLET can help reduce the long-term complications of diabetes, such as nerve damage, kidney problems, and heart disease, by keeping blood sugar levels within a healthy range.
  • Supports Weight Management: Metformin, one of the key ingredients in GLIMISAVE M1X TABLET, may also help with weight management by reducing appetite and promoting fat burning, which is an important aspect for individuals with diabetes.
  • Safe and Effective: GLIMISAVE M1X TABLET is clinically proven to be effective for managing type 2 diabetes, and it is generally well-tolerated when used as prescribed.

FAQs About GLIMISAVE M1X TABLET

Q: What is GLIMISAVE M1X TABLET used for?

A: GLIMISAVE M1X TABLET is primarily used to manage Type 2 diabetes by controlling blood sugar levels. It combines two active ingredients metformin and glimepiride working together to improve insulin sensitivity and reduce blood glucose.

Q: How does GLIMISAVE M1X TABLET work?

A: GLIMISAVE M1X TABLET contains glimepiride, which helps your body release insulin, and Metformin, which lowers blood sugar levels by improving how your body responds to insulin. This combination helps in controlling high blood sugar levels in diabetic patients.

Q: What are the common side effects of GLIMISAVE M1X TABLET?

A: Common side effects of GLIMISAVE M1X TABLET may include nausea, diarrhea, stomach upset, and dizziness. However, not everyone will experience these side effects, and most are mild and temporary.

Q: Who should avoid taking GLIMISAVE M1X TABLET?

A: GLIMISAVE M1X TABLET should be avoided by individuals with Type 1 diabetes, diabetic ketoacidosis, severe kidney problems, or those with hypersensitivity to glimepiride or metformin.

Q: Can I take GLIMISAVE M1X TABLET with other medications?

A: It is important to inform your doctor about all the medications you are taking, including over-the-counter drugs and supplements. Some medications can interact with GLIMISAVE M1X TABLET, potentially affecting its effectiveness or increasing side effects.

Q: How should GLIMISAVE M1X TABLET be taken?

A: GLIMISAVE M1X TABLET should be taken orally with food, usually once or twice a day, as advised by your doctor. The dosage will depend on your blood sugar levels and individual response to the medication.

Q: Can GLIMISAVE M1X TABLET cause low blood sugar?

A: Yes, GLIMISAVE M1X TABLET, especially the glimepiride component, can cause low blood sugar (hypoglycemia) if taken in higher doses or without adequate food intake. Symptoms may include sweating, shaking, dizziness, and confusion.

Q: Is GLIMISAVE M1X TABLET safe during pregnancy?

A: GLIMISAVE M1X TABLET Is not recommended during pregnancy, especially in the second and third trimesters. Consult your doctor to switch to safer alternatives for managing diabetes during pregnancy.

Q: Can GLIMISAVE M1X TABLET be taken for a long time?

A: GLIMISAVE M1X TABLET is generally prescribed for long-term management of Type 2 diabetes. Regular monitoring of blood sugar levels and kidney function is recommended to ensure safe and effective use over time.

Q: What should I do if I miss a dose of GLIMISAVE M1X TABLET?

A: If you miss a dose ofGLIMISAVE M1X TABLET, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses to make up for a missed one.

Q: Is it safe to consume alcohol while taking GLIMISAVE M1X TABLET?

A: It is advisable to avoid alcohol consumption while taking GLIMISAVE M1X TABLET, as it may either enhance or reduce the blood sugar-lowering effect and increase the risk of lactic acidosis.

Q: How Long Does It Take for GLIMISAVE M1X TABLETP to Show Results?

A: GLIMISAVE M1X TABLET (which contains metformin and glimepiride) generally starts to show its effects within a few days to weeks after you start taking it. However, it may take up to 1–2 weeks for you to notice significant changes in your blood sugar levels. For optimal results, it is essential to follow your doctor's instructions regarding dosage, diet, and exercise. Remember that individual responses may vary, and it’s important to monitor your blood sugar regularly.

Q: Why Choose Netmeds for Your GLIMISAVE M1X TABLET Purchase?

A: Netmeds is a trusted online pharmacy offering genuine medications, timely delivery, and competitive prices. It also provides the convenience of purchasing medication from the comfort of your home with access to expert healthcare guidance.

References

  1. KD Tripathi MD. Hormones and related drugs. Essentials of medical pharmacology. Seventh edition. New Delhi, May 2013. Page- 274.
  2. Rakesh Kumar Sahay, Vinod Mittal, G Raja Gopal, Sunil Kota, Ghanshyam Goyal, Mahesh Abhyankar, Santosh Revenkar. Glimepiride and Metformin Combinations in Diabetes Comorbidities and Complications: Real-World Evidence. September 2020. [Accessed on 7th Feb 2025]  
  3. Sanofi. Efficacy and Safety Comparison of Metformin/Glimepiride Combination Versus Each Compound Alone in New Diagnosed Type 2 Diabetes Patients (RECOMMEND). NIH U.S. National Library of Medicine. ClinicalTrials.gov. [Revised in January 2015] [Accessed on 7th Feb 2025]   
  4. Torrent pharmaceuticals Ltd. Azulix MF. Metformin Hydrochloride Prolonged Release and Glimepiride Tablets I.P. [Revised in July 2019] [Accessed on 7th Feb 2025]
  5. Sanofi-aventis group. Amaryl M. Glimepiride + Metformin. [Revised in May 2015] [Accessed on 7th Feb 2025]

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)
Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile
Last updated on 23 May 2025 | 03:44 PM(IST)
    Net Qty
    1 N
    Shelf Life
    720 Days
    Item Weight
    45 g
    Ingredient
    Glimepiride 1 mg+Metformin 500 mg
    Hsn Code
    30049099
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