GLICLAVAC MV 0.3 Tablet 10's
Get notified when this medicine is available.
Introduction About GLICLAVAC MV 0.3 TABLET
GLICLAVAC MV 0.3 TABLET is used to manage type II diabetes in patients whose blood sugar level is not controlled by diet alone. It is a combination of Gliclazide, Metformin, and Voglibose, which belongs to a group of medicines called Antidiabetic agents. Gliclazide acts by stimulating the secretion of insulin (a hormone that signals throughout the body to absorb glucose and regulate the blood sugar level) through beta-cell sulphonyl urea receptors. Metformin works by decreasing glucose production in the liver (gluconeogenesis) and increasing insulin sensitivity to absorb glucose. Voglibose inhibits the alpha-glucosidase in the intestine and manages the absorption of glucose from food, thereby reducing the blood sugar level.
Take GLICLAVAC MV 0.3 TABLET as directed by your physician. Take this medicine with a glass of water before meals.
Your doctor may advise you to take a blood and urine sugar level test before or along with the management. Do not take GLICLAVAC MV 0.3 TABLET if you have severe liver, kidney, and heart problems. GLICLAVAC MV 0.3 TABLET is not recommended for use in pregnant and breast-feeding women. Consult your doctor before taking it.
GLICLAVAC MV 0.3 TABLET is not recommended for use in children, and it should be used with caution in elderly patients. The common side effects of taking GLICLAVAC MV 0.3 TABLET are headache, nausea, constipation, indigestion, diarrhea, and abdominal pain. Consult your doctor if the side effects do not improve.
Uses Of GLICLAVAC MV 0.3 TABLET
- To manage type II diabetes mellitus
How GLICLAVAC MV 0.3 TABLET Works
GLICLAVAC MV 0.3 TABLET works effectively against diabetes, where Gliclazide acts by stimulating the secretion of insulin (a hormone that signals throughout the body to absorb glucose and regulate the blood sugar level) through beta-cell sulphonyl urea receptors. Metformin works by decreasing glucose production in the liver (gluconeogenesis) and increasing insulin sensitivity to absorb glucose. Voglibose inhibits the alpha-glucosidase in the intestine and manages the absorption of glucose from food, thereby reducing the blood sugar level.
How to use GLICLAVAC MV 0.3 TABLET
Take GLICLAVAC MV 0.3 TABLET as directed by your physician. Take this medicine with a glass of water before meals. Your doctor will decide the suitable dose and duration depending on your age, body weight, and disease condition.
Side Effects Of GLICLAVAC MV 0.3 TABLET
Common
- Nausea, vomiting, diarrhea, abdominal pain, indigestion, and constipation
- Loss of appetite
- Altered taste sensation
- Skin rashes, pale skin, redness, itching, and hives
- Anemia, fever, or sore throat, or develop bruising or bleeding
- Signs of low sodium levels like whole-body dizziness, fatigue, lethargy, weakness, or thirst
Stop taking GLICLAVAC MV 0.3 TABLET and contact your doctor immediately if you experience any of the following side effects:
- Allergic reaction like skin rash or angioedema (rapid swelling of tissues such as the eyelids, face, lips, mouth, tongue, or throat that may result in breathing difficulty)
- Flu-like symptoms and a rash on the face, then an extended rash with a high temperature, the rash progressing to widespread blistering or peeling of the skin
- Symptoms of low blood sugar level (hypoglycemia) such as sweating, clammy skin, trembling, weakness, double vision, palpitations, confusion, headache, hunger, feeling or being sick, sleep disorders, feeling agitated, unable to concentrate, drowsiness, loss of consciousness, slowed reactions, depression, trouble seeing or speaking, paralysis, numbness, dizziness, loss of self-control, sensing or seeing things that are not there, difficulty breathing, slowed or faster heartbeat, chest pains
- Hepatitis or liver failure causing fatigue, excessive tiredness, weakness, loss of appetite, weight loss, fever, changes in liver enzymes, and jaundice (yellowing of the skin or whites of the eyes)
- Lactic acidosis
How To Manage Side Effects
Diarrhea
Drink plenty of clear fluids, like water, diluted fruit juices, or oral rehydration solutions, to stay hydrated. Avoid alcohol, caffeine, and very sugary drinks, as they can worsen dehydration. Eat bland foods like bananas, rice, applesauce, and toast. These are easy to digest and can help firm up the stools. Probiotics, found in yogurt or supplements, may help restore the balance of gut bacteria. Practice good hand hygiene to prevent the spread of infection. Consult your doctor if diarrhea worsens.
Headache
Ensure adequate fluid intake, as dehydration can cause headaches. Maintain a consistent sleep schedule, aiming for 7-9 hours of quality sleep per night. Eat balanced meals at regular intervals to avoid blood sugar fluctuations that can trigger headaches. Practice relaxation techniques such as meditation, yoga, or deep breathing exercises to reduce stress levels. Engage in regular physical exercise, which can help reduce the frequency and severity of headaches. Apply a cold pack or warm compress to the forehead or neck to alleviate pain. Consult your doctor if a headache persists.
Nausea And Vomiting
Eating small amounts more frequently can help prevent the stomach from becoming too full and reduce nausea. Opt for bland, easy-to-digest foods like crackers, toast, rice, bananas, and applesauce. Avoid strong smells and spicy foods, as they can trigger or worsen nausea. Sip on clear liquids like water, broth, or herbal teas. Electrolyte solutions can be beneficial if nausea is accompanied by vomiting.
Skin rash Or Itching
Keep the affected area clean and dry and avoid scratching to prevent further irritation or infection. Apply calamine lotion to help reduce itching and inflammation. Applying cool compresses and wearing loose, breathable clothing can also provide relief. If the rash persists, consult your doctor.
Warning & Precautions
Pregnancy
ContraindicatedGLICLAVAC MV 0.3 TABLET is not recommended for use by pregnant women. Consult your doctor before taking it.
Breastfeeding
ContraindicatedGLICLAVAC MV 0.3 TABLET is not recommended for use by breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionGLICLAVAC MV 0.3 TABLET does not affect your ability to drive or operate any machinery. Take special care while driving or operating machines since it may cause difficulty in concentration.
Alcohol
ContraindicatedDo not consume alcohol while taking GLICLAVAC MV 0.3 TABLET, as it may increase the risk of side effects.
Kidney
ContraindicatedGLICLAVAC MV 0.3 TABLET is not recommended for use in patients with severe kidney problems. Consult your doctor before taking GLICLAVAC MV 0.3 TABLET.
Liver
ContraindicatedGLICLAVAC MV 0.3 TABLET is not recommended for use in patients with severe liver problems. Consult your doctor before taking GLICLAVAC MV 0.3 TABLET.
Allergy
ContraindicatedDo not take GLICLAVAC MV 0.3 TABLET if you are allergic to Gliclazide, Metformin, Voglibose, or any ingredients of this medicine.
Lungs
ContraindicatedGLICLAVAC MV 0.3 TABLET is not recommended for use in patients with lung or bronchial infections. Consult your doctor before taking GLICLAVAC MV 0.3 TABLET.
Heart Disease
ContraindicatedGLICLAVAC MV 0.3 TABLET is not recommended for use in patients with acute heart failure or who have recently had a heart attack. Consult your doctor before taking GLICLAVAC MV 0.3 TABLET.
Use In Pediatrics
ContraindicatedGLICLAVAC MV 0.3 TABLET is not recommended for use with children. Consult your doctor for advice before taking GLICLAVAC MV 0.3 TABLET.
Use In Geriatrics
Use with CautionGLICLAVAC MV 0.3 TABLET should be used with caution with elderly patients. Consult your doctor for advice.
Others
GLICLAVAC MV 0.3 TABLET is not recommended for use if you:
- Have porphyria (a disorder of red blood cells)
- Have diabetes ketoacidosis
- Have type 1 diabetes
- Have to undergo any operation or have previously suffered from severe trauma or infection
- Have severe hyperglycemia (high blood glucose).
- Have dehydration problems
- Have gastrointestinal obstruction
Before taking GLICLAVAC MV 0.3 TABLET, inform your doctor if you:
- Have an inherited condition where your red blood cells don’t produce enough of the enzyme G6PD (glucose-6 phosphate dehydrogenase)
- Have hormone-induced disorders such as functional disorders of the thyroid gland, pituitary gland, or adrenal cortex
- Have low blood sugar (hypoglycaemia)
- Have lactic acidosis
Interactions
A. Drug-Drug interactions:
- Antidiabetic (Ex. glimepiride, liraglutide, or insulin)
- Antibiotics (Ex. sulphonamides, clarithromycin)
- Cardiovascular agents (Ex. propranolol, atenolol, captopril, losartan, nifedipine, and diazoxide)
- Anti-infectives (such as co-trimoxazole, fluconazole, rifampicin, chloramphenicol, sulfafurazole or tetracycline, sulfonamides, and clarithromycin)
- Anticoagulants (Ex. warfarin)
- Antidepressants (Ex. moclobemide, St. John’s Wort)
- Antimanic (Ex. lithium)
- Antipsychotic (Ex, prochlorperazine, chlorpromazine)
- Corticosteroids (Ex. prednisolone, glucocorticoids, and tetracosactrin)
- NSAIDs (such as phenylbutazone, azapropazone, ibuprofen, celecoxib, and aspirin)
- Diuretics (Ex. bendroflumethiazide, hydrochlorothiazide, and furosemide)
- Oral contraceptives (Ex. levonorgestrel)
- Antigout (Ex. sulfinpyrazone)
- Anticancer agent (Ex. aminoglutethimide)
- Hormones (like testosterone, octreotide, and thyroxine)
- Antiulcer agent (Ex. cimetidine)
- Antilipidemic (Ex. clofibrate)
- Antiarrhythmic (Ex. disopyramide)
- Laxatives (Ex. lactulose)
- Antiasthma (Ex. salbutamol and terbutaline)
- Beta-2 adrenergic agonist (Ex. ritodrine)
- Androgenic hormones (Ex. danazol)
Overdosage:
If you or anyone else accidentally used too much of GLICLAVAC MV 0.3 TABLET, consult your doctor immediately or visit any nearby hospital. Symptoms of an overdose are low blood sugar, such as sweating, trembling, weakness, double vision, palpitations, confusion, and symptoms of lactic acidosis that are non-specific, such as vomiting, abdominal pain with muscle cramps, a feeling of being unwell with severe tiredness, and difficulty breathing.
Synopsis
| Drug | : | Gliclazide, Metformin, and Voglibose |
| Pharmacological Category | : | Sulfonylureas, biguanides, and alpha-glucosidase inhibitors |
| Therapeutic Indication | : | Type II diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep GLICLAVAC MV 0.3 TABLET out of reach of children
- Store at normal temperature
FAQs About GLICLAVAC MV 0.3 TABLET
Q: What is GLICLAVAC MV 0.3 TABLET, and why is it given?
A: GLICLAVAC MV 0.3 TABLET contains Gliclazide, Metformin, and Voglibose, which are collectively used to manage type II diabetes (noninsulin-dependent diabetes) in patients whose blood sugar level is not controlled by diet alone.
Q: Can I drink alcohol while taking GLICLAVAC MV 0.3 TABLET?
A: Avoid consumption of alcohol while taking GLICLAVAC MV 0.3 TABLET, as it may increase the risk of side effects. Consult your doctor for advice.
Q: Is GLICLAVAC MV 0.3 TABLET safe for pregnant and breast-feeding women?
A: GLICLAVAC MV 0.3 TABLET is not recommended for use in pregnant women, if you are planning to become pregnant, or in breast-feeding women. Consult your doctor before taking it.
Q: Is GLICLAVAC MV 0.3 TABLET safe for use by children?
GLICLAVAC MV 0.3 TABLET is not recommended for use with children. Your physician will prescribe you any other suitable medicine. Consult your doctor for advice before taking GLICLAVAC MV 0.3 TABLET.
Q: Does GLICLAVAC MV 0.3 TABLET cause skin rashes?
A: Yes, it may cause skin rash in some individuals. Try to avoid hot showers because they may cause skin irritation. Avoid frequent contact with and rubbing over the affected area. Use sunscreen and protective clothing when outdoors. If this symptom does not get better, speak to a doctor.
Q: Can GLICLAVAC MV 0.3 TABLET interact with other medications?
A: Yes, it can interact with other medications, affecting how they work or increasing the risk of side effects. Inform your doctor about all the other medications you are taking.
Q: What should I do if I experience severe side effects?
A: Contact your doctor immediately if you experience severe side effects such as severe hypoglycemia, allergic reactions, or symptoms of lactic acidosis (such as unusual muscle pain, breathing difficulty, or unusual tiredness).
Q: What are the side effects of taking GLICLAVAC MV 0.3 TABLET?
A: The common side effects of taking GLICLAVAC MV 0.3 TABLET are headache, nausea, constipation, indigestion, diarrhea, and abdominal pain. Consult your doctor if the side effects do not improve.
Q: Do I need to monitor my blood sugar levels regularly while taking this medication?
A: Yes, regular monitoring of blood sugar levels is important to ensure the medication is working effectively and to avoid hypoglycemia or hyperglycemia.
Q: Are there any specific dietary restrictions while taking GLICLAVAC MV 0.3 TABLET?
A: Follow your doctor's advice regarding diet. Generally, maintain a balanced diet with controlled carbohydrate intake to manage blood sugar levels effectively.
Q: Can I buy GLICLAVAC MV 0.3 TABLET online?
A: You can buy GLICLAVAC MV 0.3 TABLET online through platforms like Netmeds, an online pharmacy that offers a hassle-free way to get your medications delivered to your doorstep. If you wish to buy GLICLAVAC MV 0.3 TABLET on Netmeds, you need a prescription from a registered medical practitioner. Netmeds has made buying online medicines easier for consumers and is one of India's leading online pharmacies.
References
1. KD. Tripathi. Oral Antidiabetic drugs. Essentials of Medical Pharmacology. Eighth Edition. 2019. Page – 294.
2. Yi-Wei Wang, Si-Jia He, Xiao Feng, Jin Cheng, Yun-Tao Luo, Ling Tian, and Qian Huang. Metformin: a review of its potential indications. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. August 2011. [Accessed on 27th May 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574599/
3. Gijs W. D. Landman,Geertruide H. de Bock,Kornelis J. J. van Hateren, Peter R. van Dijk, Klaas H. Groenier, Rijk O. B. Gans, Sebastiaan T. Houweling, Henk J. G. Bilo, and Nanne Kleefstra. Safety and Efficacy of Gliclazide as Treatment for Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Trials. NIH National Library of Medicine, National Center for Biotechnology Information, PubMed Central. February 2014. [Accessed on 27th May 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922704/
4. Les Laboratories Servier Industrie. Electronic Medicines Compendium (EMC). [Revised in July 2022] [Accessed on 27th May 2024] https://www.medicines.org.uk/emc/files/pil.1321.pdf
5. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 27th May 2024] https://www.medicines.org.uk/emc/files/pil.987.pdf
6. Biocon Limited. [Accessed on 27th May 2024] https://www.biocon.com/docs/prescribing_information/diabetology/volicose_pi.pdf
Useful Diagnostic Tests
- HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
- Blood Glucose Fasting (FBS)
- Random Blood Sugar (RBS)
- Post Prandial Blood Sugar (PPBS)
- Vital Diabetes Care
- Extended Diabetes Care
- Advance Diabetes Care
- Comprehensive Diabetes Care
Author Details
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.