Introduction About GEMITROL KIT

Prior to the management with GEMITROL KIT, your doctor might ask you to take some diagnostic tests.

Before taking GEMITROL KIT, inform your doctor if you have kidney diseases, stomach or digestive problems, problems swallowing, difficulty in movement such as after an operation, low blood calcium, difficulty in absorption, and plan to undergo dental surgery.

GEMITROL KIT is not recommended for use in patients with high levels of calcium in the blood, extra deposits of calcium in the body, abnormalities of the esophagus, and an inability to stand or sit upright.

GEMITROL KIT should be used with caution in pregnant and breast-feeding women. GEMITROL KIT is not intended for use by children.

The most common side effects of taking GEMITROL KIT are pain, including back and joint pain, stomach pain, and heartburn. Ask for your doctor’s advice if any of these worsen or don’t improve.

Inform your physician if you are taking any of the following drugs before taking GEMITROL KIT:

• other medicines containing Vitamin D
• diuretics (water tablets) such as bendroflumethiazide, chlortalidone, and indapamide (used to manage high blood pressure) and digoxin (used to manage heart diseases)
• antacids such as magnesium sulphate (used to manage indigestion)
• steroids such as hydrocortisone, prednisolone, and dexamethasone (used to manage pain and inflammation)
• cholestyramine (used in managing high levels of cholesterol)
• ergocalciferol, cholecalciferol (used in the management of low calcium levels in the blood)

B. Drug-food interactions:

• avoid taking any vitamins or food supplements that contain vitamin D
• avoid eating foods rich in vitamin D

Overdosage:

If you or anyone else accidentally takes too much of GEMITROL KIT, consult your doctor immediately or visit the nearby hospital.

A: GEMITROL KIT is a combination of Calcitriol, Calcium Carbonate, Risedronate, and Zinc, which belong to the group of medicines called Vitamin D metabolites, Minerals and Bone Conserving Agents, respectively. GEMITROL KIT is indicated in the management of osteoporosis in postmenopausal women.

Q: Can GEMITROL KIT affect oral health?

A: Patients taking GEMITROL KIT should take care of their oral hygiene. If, after taking GEMITROL KIT, they have any symptoms like loosening of teeth, pain in the mouth or jaw, delayed wound healing, or infection after extraction, they should immediately talk to their doctor.

Q: Is GEMITROL KIT safe for use in pregnant and breast-feeding women?

A: GEMITROL KIT should be used with caution in pregnant and breast-feeding women. Consult your doctor before taking it.

Q: What are the dietary instructions that need to be followed while taking GEMITROL KIT?

A: Avoid the consumption of vitamins or food supplements that contain vitamin D while you are taking GEMITROL KIT. Avoid eating foods that have vitamin D added. It is very important to keep following the diet that your doctor has given you. If you change the amount of calcium or vitamin D you have in your diet while taking GEMITROL KIT, this can increase the risk of side effects. Also, drink plenty of water and other fluids to keep yourself hydrated.

Q: What precautions should I follow while taking GEMITROL KIT?

A: Take GEMITROL KIT as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Do not lie down for at least 30 minutes after you take GEMITROL KIT and after you eat your first meal of the day.

2. John K Brooks, Allen J Gilson, Arnold J Sindler, Steven G Ashman, Kevin G Schwartz, Nikolaos G Nikitakis. Osteonecrosis of the jaws associated with use of risedronate: report of 2 new cases. NIH. National Library of Medicine, National center for biotechnology information. Pubmed.gov. June 2007. [Accessed on 7th February 2024] https://pubmed.ncbi.nlm.nih.gov/17223592/

3. Sandeep Kalra, Veena Jain. Dental complications and management of patients on bisphosphonate therapy: A review article. NIH. National Library of Medicine, National center for biotechnology information. PubMed.gov. November 2012. [Accessed on 7th February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942225/

4. Masayoshi Yamaguchi. Role of nutritional zinc in the prevention of osteoporosis. NIH. National Library of Medicine, National center for biotechnology information. PubMed.gov. May 2010. [Accessed on 7th February 2024] https://pubmed.ncbi.nlm.nih.gov/20035439/

5. NIH. National Library of Medicine, National center for biotechnology information. PubChem. Risedronate Sodium. [Accessed on 7th February 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Risedronate-sodium

6. Torrent Pharmaceuticals Ltd. Gemitrol Kit. [Revised in January 2020]. [Accessed on 7th February 2024] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1083.pdf

7. Drug Bank. Calcitriol. [Accessed on 7th February 2024] https://go.drugbank.com/drugs/DB00136

8. Drug Bank. Calcium Carbonate. [Accessed on 7th February 2024] https://go.drugbank.com/drugs/DB06724