Introduction About GEMER DAPA XR 10/2/1000 TABLET

GEMER DAPA XR 10/2/1000 TABLET is a combination of Dapagliflozin, Glimepiride, and Metformin, which belongs to the group of medicines called Antidiabetic agents. It is used as an adjunct to diet and exercise to improve glycemic control among patients with type II diabetes mellitus when management with single agents does not result in adequate response.

Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused by inadequate production of a hormone called insulin (produced by the pancreas to metabolize glucose) in the body or by inadequate sensitivity of body cells to the actions of insulin.

Before taking GEMER DAPA XR 10/2/1000 TABLET, inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you have any eye problems, hormonal imbalance, alcoholism, or if you are malnourished or starved on an irregular diet as a precaution.

GEMER DAPA XR 10/2/1000 TABLET is strictly not recommended for use in patients with type I diabetes mellitus, bladder cancer, severe heart failure or lactic acidosis, severe low blood pressure, or severe dehydration. It is also not suitable for use in pregnant or breastfeeding women.

Along with the management, follow the diet and lifestyle changes advised by your doctor to achieve better results. Avoid smoking and consumption of alcohol while taking GEMER DAPA XR 10/2/1000 TABLET, as it may aggravate your existing condition. During therapy with GEMER DAPA XR 10/2/1000 TABLET, your doctor might regularly monitor your blood sugar levels and kidney functions to avoid the risk of unwanted side effects.

The most common side effects of taking GEMER DAPA XR 10/2/1000 TABLET are low blood sugar levels, nausea, stomach upset, constipation, sore throat, muscle pain, headache, dizziness, genital infections, back pain, and passing more urine. Consult your doctor if any of these side effects worsen.

Uses Of GEMER DAPA XR 10/2/1000 TABLET

• It is used as an adjunct to diet and exercise to improve glycemic control among patients with type II diabetes mellitus.

How GEMER DAPA XR 10/2/1000 TABLET Works

GEMER DAPA XR 10/2/1000 TABLET contains three medicines, namely, metformin, glimepiride, and dapagliflozin. Metformin and glimepiride stimulate the pancreas to secrete more insulin (a hormone involved in glucose metabolism). They also make our body more sensitive to insulin, which helps in digesting the circulating sugars (glucose) in the blood, thereby reducing blood sugar levels. Additionally, metformin can also reduce the glucose produced by the liver and reduce its absorption in the body.

Dapagliflozin is an SGLT-2 inhibitor. It works by blocking the action of a protein called SGLT-2 in the kidneys. This action manages the reabsorption of glucose and sodium ions in the kidneys. As a result, it excretes excess glucose from the body in the form urine.

How to use GEMER DAPA XR 10/2/1000 TABLET

Take GEMER DAPA XR 10/2/1000 TABLET preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and disease condition.

Do not stop taking GEMER DAPA XR 10/2/1000 TABLET unless your doctor advises you to stop.

Side Effects Of GEMER DAPA XR 10/2/1000 TABLET

How To Manage Side Effects

Constipation

Taking GEMER DAPA XR 10/2/1000 TABLET with meals may reduce the chances of constipation. However, if you experience constipation, eat plenty of fiber-rich foods, such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if constipation persists.

Diarrhea

Hydrate yourself by drinking plenty of fluids, such as water or fruit juices. Consuming ORS can also be beneficial. Do not manage diarrhea on your own. Consult your doctor if your diarrhea becomes uncontrollable.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol. Consult your doctor if your dizziness worsens.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids, such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Hypoglycemia

Have foods rich in sugars, such as fruit juices, glucose drinks, candies, honey, or biscuits. Check your blood sugar after 10 minutes. If you have not gained the optimum level, take another sugary snack or drink and check the blood sugar again. Consult your doctor if there is no improvement in your condition.

Nausea And Vomiting

Take GEMER DAPA XR 10/2/1000 TABLET with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if your nausea worsens.

Skin Conditions

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Warning & Precautions

Pregnancy

Contraindicated

GEMER DAPA XR 10/2/1000 TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.

Breastfeeding

Contraindicated

GEMER DAPA XR 10/2/1000 TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Do not drive or operate any heavy tools or machines if your ability is affected by GEMER DAPA XR 10/2/1000 TABLET.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking GEMER DAPA XR 10/2/1000 TABLET, as it may increase the risk of unwanted side effects.

Kidney

Consult your doctor

GEMER DAPA XR 10/2/1000 TABLET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with mild to moderate kidney problems. Therefore, consult your doctor before taking it.

Liver

Consult your doctor

GEMER DAPA XR 10/2/1000 TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with mild to moderate liver problems. Therefore, consult your doctor before taking it.

Allergy

Contraindicated

Do not take GEMER DAPA XR 10/2/1000 TABLET if you are allergic to Glimepiride, Metformin, or Dapagliflozin.

Heart Disease

Consult your doctor

GEMER DAPA XR 10/2/1000 TABLET is not recommended for use in patients with severe heart problems (such as heart failure). It should be used with caution in patients with other heart problems. Therefore, consult your doctor before taking it.

Use In Pediatrics

Contraindicated

GEMER DAPA XR 10/2/1000 TABLET is not recommended for use in children and in adolescents (aged below 18 years). Therefore, consult your doctor before taking it.

Use In Geriatrics

Use with Caution

GEMER DAPA XR 10/2/1000 TABLET should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it.

Interactions

Before taking GEMER DAPA XR 10/2/1000 TABLET, inform your doctor if you are taking any of the following medicines:

• Other medicines used to regulate blood sugar levels (such as teneligliptin, rosiglitazone, insulin, and gliclazide)
• Medicines used in pain management (Ex. aspirin, ibuprofen, celecoxib, phenylbutazone, azopropazone, oxyphenbutazone, prednisolone, betamethasone)
• Medicines for managing urinary infections (amikacin, nitrofurantoin, sulfamethoxazole)
• Antibiotics (such as tetracyclines, chloramphenicol, ciprofloxacin, and clarithromycin); antifungals (fluconazole, miconazole, and isuvaconazole)
• medicines used for blood thinning (Ex. warfarin)
• Hormones (Ex. testosterone, estradiol)
• Medicines used in the management of mental illnesses (such as moclobemide, isocarboxazid, phenelzine, tranylcypromine, fluoxetine, chlorpromazine, prochlorperazine, and lithium)
• Antihyperlipidemics (Ex. fenofibrate, nicotinic acid, colesevelam)
• Antihypertensives (Ex. enalapril, lisinopril, ramipril, atenolol, propranolol, telmisartan, olmesartan, clonidine, guanethidine, reserpine, prazosin, doxazosin)
• medicines used to manage gout (Ex. allopurinol, probenecid, sulfinpyrazone)
• medicines used in the management of cancer (Ex. cyclophosphamide, ifosfamide, trofosfamide, vandetanib, crizotinib, and olaparib)
• medicines used in the management of allergic rhinitis (Ex. tritoqualine)
• Water pills (Ex. hydrochlorothiazide)
• Anti-asthmatics (Ex. salbutamol, terbutaline)
• adrenaline (a medicine used for anaphylaxis)
• Medicines used for constipation (Ex. lactulose, liquid paraffin)

Overdosage:

If you or anyone else accidentally took more GEMER DAPA XR 10/2/1000 TABLET, you may experience the signs of hypoglycemia (such as increased hunger, sweating, headache, feeling clammy, restless or aggressive, shakiness, fast heartbeat, and confusion). To manage this, consume any sugary food immediately. If the symptoms do not improve or worsen, contact your doctor immediately. Other symptoms of overdose might include vomiting, stomach pain with muscle cramps, feeling generally unwell with severe tiredness, and difficulty breathing.

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FAQs About GEMER DAPA XR 10/2/1000 TABLET

Q: What is GEMER DAPA XR 10/2/1000 TABLET used for?

A: GEMER DAPA XR 10/2/1000 TABLET is used as an adjunct to diet and exercise to improve glycemic control among patients with type II diabetes mellitus when management with single agents does not result in adequate response.

Q: How and when to take GEMER DAPA XR 10/2/1000 TABLET?

A: Take GEMER DAPA XR 10/2/1000 TABLET, preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and disease condition.

Q: How long should I take GEMER DAPA XR 10/2/1000 TABLET?

A: You need to take GEMER DAPA XR 10/2/1000 TABLET as long as your doctor or physician prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and disease condition.

Q: What is the best time to take GEMER DAPA XR 10/2/1000 TABLET?

A: GEMER DAPA XR 10/2/1000 TABLET must be taken with meals to avoid gastrointestinal side effects.

Q: What to do if I forgot to take a dose of GEMER DAPA XR 10/2/1000 TABLET?

A: If you forgot to take a dose of GEMER DAPA XR 10/2/1000 TABLET, take it as soon as you remember. However, if it is time for the next dose of GEMER DAPA XR 10/2/1000 TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of GEMER DAPA XR 10/2/1000 TABLET to compensate for the missed ones.

Q: Can I stop taking GEMER DAPA XR 10/2/1000 TABLET without consulting your doctor?

A: No. You should not stop taking GEMER DAPA XR 10/2/1000 TABLET without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using GEMER DAPA XR 10/2/1000 TABLET, consult your doctor for advice.

Q: Will taking a higher dose of GEMER DAPA XR 10/2/1000 TABLET be more effective?

A: No, taking a higher dose of GEMER DAPA XR 10/2/1000 TABLET will not be effective; rather, it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.

Q: Can I take medication for high blood pressure along with GEMER DAPA XR 10/2/1000 TABLET?

A: It is not advisable to take medicines to control blood pressure while taking GEMER DAPA XR 10/2/1000 TABLET without consulting your doctor, as they have known interactions with GEMER DAPA XR 10/2/1000 TABLET.

Q: How to manage the side effects of GEMER DAPA XR 10/2/1000 TABLET?

A: Low blood sugar is a common side effect of taking GEMER DAPA XR 10/2/1000 TABLET. Try to have sugar-rich food items such as fruit juice, glucose tablets or gel, soft drinks, honey, or sugary candy. Check your blood sugar after 10 minutes. If not at the optimum level, take another sugary snack or drink and check the blood sugar levels once again. If your condition does not improve, consult your doctor immediately.

Q: Can GEMER DAPA XR 10/2/1000 TABLET be taken with insulin?

A: Co-administration of GEMER DAPA XR 10/2/1000 TABLET with insulin is considered risky as they can increase the chances of hypoglycemia (low blood sugar levels). Therefore, consult your doctor before taking it.

Q: Can GEMER DAPA XR 10/2/1000 TABLET be used in pregnant women?

A: GEMER DAPA XR 10/2/1000 TABLET is not recommended for use in pregnant women. Therefore, consult your doctor for advice before taking it.

Q: What are the side effects of taking GEMER DAPA XR 10/2/1000 TABLET?

A: The most common side effects of taking GEMER DAPA XR 10/2/1000 TABLET are low blood sugar levels, nausea, stomach upset, constipation, sore throat, muscle pain, headache, dizziness, genital infections, back pain, and passing more urine. Consult your doctor if any of these side effects worsen.

Q: Can GEMER DAPA XR 10/2/1000 TABLET cause urinary tract infection?

A: Yes, taking GEMER DAPA XR 10/2/1000 TABLET may cause urinary tract infections in few people. Not every individual gets the side effect, so it is always better to practice good hygiene. Contact your doctor for advice.

Q: Can GEMER DAPA XR 10/2/1000 TABLET cause constipation?

A: Yes. Constipation is a common side effect of using GEMER DAPA XR 10/2/1000 TABLET. Eat plenty of fiber-rich foods, such as fresh fruits, vegetables, and cereals, as well as drink plenty of water and exercise more regularly while taking this medicine. Contact your doctor if this side effect bothers you.