Introduction About GAVIR 500 INJECTION

GAVIR 500 INJECTION contains Ganciclovir, which belongs to the group of medicines called Antivirals. It is used to manage cytomegalovirus (CMV) retinitis in people who have acquired immunodeficiency syndrome (AIDS) or in patients undergoing chemotherapy. It is also used to manage cytomegalovirus (CMV) disease in people who have received a solid organ transplant and are at risk of developing CMV disease.

It is not recommended if you have any pre-existing cytopenia or a history of cytopenic reactions to other drugs, chemicals or irradiation. Inform your doctor if you have kidney, liver or heart diseases. Contact your doctor before receiving this medicine.

GAVIR 500 INJECTION is not recommended for use by pregnant or breastfeeding women. This medicine is not recommended for use by children. The most common side effects of receiving GAVIR 500 INJECTION are diarrhea, nausea, headaches and dizziness. Contact your doctor if any of the side effects worsen.

Uses Of GAVIR 500 INJECTION

• Manage cytomegalovirus (CMV) retinitis in people who have acquired immunodeficiency syndrome (AIDS) or in patients undergoing chemotherapy
• Manage and manages cytomegalovirus (CMV) disease in people who have received a solid organ transplant and are at risk of developing CMV disease

How GAVIR 500 INJECTION Works

Ganciclovir manages the multiplication of viruses in human cells. This stops the virus from producing new viruses and clears up your infection.

How to use GAVIR 500 INJECTION

This medicine will be administered intravenously by your doctor or nurse. Your doctor will administer the correct dose and duration for you depending on your age, body weight and disease condition.

Side Effects Of GAVIR 500 INJECTION

How To Manage Side Effects

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep you hydrated. Do not take any medicine on your own for managing diarrhea. Contact your doctor if the symptom did not improve.

Warning & Precautions

Pregnancy

GAVIR 500 INJECTION is generally not recommended for use in pregnant women. Consult your doctor before receiving it.

Breastfeeding

It is not known whether GAVIR 500 INJECTION passes into the breast milk. Consult your doctor before receiving it.

Kidney

GAVIR 500 INJECTION should be used with caution in patients with kidney disease or who are receiving hemodialysis. Consult your doctor before receiving it.

Liver

GAVIR 500 INJECTION should be used with caution in patients with liver disease. Consult your doctor before receiving it.

Allergy

Do not receive GAVIR 500 INJECTION if you are allergic to Ganciclovir.

Heart Disease

GAVIR 500 INJECTION should be used with caution in patients with heart disease. Consult your doctor before receiving it.

Interactions

A. Drug-Drug interactions:

Inform your doctor if you are receiving any of the following medicine:

• didanosine, zidovudine (manages HIV infection)
• probenecid (manages gout)
• imipenem-cilastatin (manages infection)
• cyclosporin
• mycophenolate mofetil

Overdosage:

GAVIR 500 INJECTION will be administered to you only by a doctor or a nurse in a hospital, so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.

Synopsis

More Information

• Keep this medicine out of the sight and reach from children
• Store at room temperature

FAQs About GAVIR 500 INJECTION

Is GAVIR 500 INJECTION effective?

GAVIR 500 INJECTION is effective if used according to the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using too early, the symptoms may return or worsen.

How is GAVIR 500 INJECTION administered?

It should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being managed for and will be decided by your doctor. Follow your doctor’s instructions carefully to get the maximum benefit.

Is GAVIR 500 INJECTION safe?

It is safe if used according to the dose and duration advised by your doctor. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

References

1. Alice Tseng, PharmD and Michelle Foisy, PharmD. The role of ganciclovir for the management of cytomegalovirus retinitis in HIV patients: Pharmacological review and update on new developments, May 1996. [Accessed on 3rd December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327402/

2. Auro Pharma Inc. [Revised on Jan 16, 2018] [Accessed on 3rd December 2022] https://www.ema.europa.eu/en/documents/referral/cymevene-article-30-referral-annex-iii_en.pdf

3. Ganciclovir. CDSCO. [Accessed on 3rd December 2022] https://cdscoonline.gov.in/CDSCO/Drugs

4. Medline plus. [Revised on May 2016] [Accessed on 3rd December 2022] https://medlineplus.gov/druginfo/meds/a605011.html