Galvus Met 50/850mg Tablet 15'S
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Introduction About GALVUS MET 50/850MG TABLET
GALVUS MET 50/850MG TABLET is used in the management of type II diabetes mellitus. It contains a combination of metformin and vildagliptin as active ingredients which works by making your body utilize the circulating blood glucose levels.
Take Galvus Met Tablet with food to avoid stomach upset. Before taking this medicine, inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you are suffering from type I diabetes, severe infections, pancreatic problems, malnutrition and vitamin B12 deficiency as a precaution.
Do not take GALVUS MET 50/850MG TABLET without consulting your doctor if you are pregnant or breastfeeding. Avoid consumption of alcohol while taking this medicine, as it may increase the risk of severe side effects.
The most common side effects of taking GALVUS MET TABLET are nausea, vomiting, stomach pain, headache, low blood sugar, and diarrhea. Contact your doctor if any of the symptoms worsen.
Uses Of GALVUS MET 50/850MG TABLET
- Management of type II diabetes mellitus
How GALVUS MET 50/850MG TABLET Works
GALVUS MET TABLET contains a combination of metformin and vildagliptin. Metformin makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body cells utilize more of the circulating blood glucose. Additionally, it can stop glucose production by the liver and reduce its absorption in the body.
Vildagliptin controls blood sugar levels by blocking the actions of an enzyme called dipeptidyl peptidase (DPP)-4 that indirectly increases insulin secretion in the body. Collectively, this medicine controls blood sugar levels in patients with type II diabetes.
How to use GALVUS MET 50/850MG TABLET
- The dose is usually prescribed by your doctor based on your blood sugar levels. Typically, it is taken once or twice a day with meals
- It should always be taken with food to reduce the risk of stomach upset
- Swallow the tablet with a glass of water, without crushing or chewing it.
- Take this medicine at the same time each day to maintain consistent blood sugar control.
- Always follow the dosing instructions given by your healthcare provider and do not alter the dose unless advised
Side Effects Of GALVUS MET 50/850MG TABLET
Common Side Effects of GALVUS MET 50/850MG TABLET:
- Nausea, Vomiting
- Diarrhoea, Stomach pain, Loss of appetite, Constipation
- Dizziness, Headache
- Metallic taste
- Low blood glucose
- Trembling or poor balance
- Joint pain, tiredness
- Swollen hands, ankles, or feet (oedema)
Stop taking this medicine and contact your doctor immediately if you experience any of the following side effects:
- Symptoms of lactic acidosis (such as vomiting, stomach pain, decreased heartbeat, difficulty breathing, muscle cramps, general weakness with severe tiredness, or reduced body temperature)
- Signs of an inflamed pancreas (severe and persistent pain in the abdomen with or without nausea or vomiting)
Warning & Precautions
Pregnancy
ContraindicatedGALVUS MET TABLET is not recommended for use if you are pregnant or think you may be pregnant.
Breastfeeding
GALVUS MET 50/850MG TABLET is not recommended for use in breastfeeding women. Consult your doctor for advice before use.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you experience dizziness after taking this medicine.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking GALVUS MET TABLET as it may increase the risk of side effects.
Kidney
ContraindicatedGALVUS MET 50/850MG TABLET is not recommended in patients with severely reduced kidney function.
Liver
ContraindicatedGALVUS MET 50/850MG TABLET is not recommended for use in patients with liver disease.
Allergy
ContraindicatedDo not take GALVUS MET TABLET if you are allergic (hypersensitive) to metformin or vildagliptin.
Heart Disease
ContraindicatedGALVUS MET 50/850MG TABLET is not recommended in patients who recently had a heart attack or heart failure or any signs of heart problems such as serious blood circulation problems or difficulty breathing.
Use In Pediatrics
ContraindicatedGALVUS MET TABLET is not recommended for use in children and adolescents less than 18 years of age due to a lack of safety and effectiveness.
Use In Geriatrics
Use with CautionGALVUS MET 50/850MG TABLET should be used with caution in elderly patients above 65 years of age, especially in patients with impaired kidney function.
Others
GALVUS MET 50/850MG TABLET is not recommended for you if you have:
- Type 1 diabetes mellitus
- Uncontrolled diabetes (with severe low blood sugar levels, nausea, vomiting, diarrhea, rapid weight loss, ketoacidosis, or lactic acidosis)
- Severe infection or seriously dehydrated
- Are going to have a contrast x-ray (a specific type of x-ray involving an injectable dye)
Before taking this medicine, inform your doctor if you have or had:
- Disease of the pancreas
- Going to undergo any surgery
- Vitamin B12 deficiency
- Malnutrition with adrenal or pituitary insufficiency
Interactions
Before taking GALVUS MET 50/850MG TABLET, inform your doctor if you are taking any of these medicines:
- Glucocorticoids (Ex. dexamethasone and prednisolone)
- Beta-2 agonists (Ex. albuterol and terbutaline)
- Diuretics (Ex. chlorthalidone and hydrochlorothiazide)
- NSAID’s (Ex. Ibuprofen and celecoxib)
- Angiotensin-converting enzyme (ACE) inhibitors (Ex. enalapril, lisinopril)
- Angiotensin II receptor antagonists (Ex. losartan, telmisartan)
- Antidiabetics (Ex. glimepiride, glipizide)
- Anti-anginal (Ex. Ranolazine)
- Anti-viral agents (Ex. Dolutegravir)
- Kinase inhibitors (Ex. Vandetanib)
- H2 blockers (Ex. Cimetidine)
Overdosage:
If you or anyone else accidentally takes too much of GALVUS MET 50/850MG TABLET, consult your doctor immediately. Overdosage symptoms of GALVUS MET 50/850MG TABLET might include low blood sugar levels, lactic acidosis, muscle pain, mild and transient burning or tickling sensations in the body, fever, and oedema.
Synopsis
| Drug | : | metformin and vildagliptin |
| Pharmacological Category | : | Biguanides, Dipeptidyl peptidase 4 inhibitors |
| Therapeutic Indication | : | Type II diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
To know more about this medicine:
FAQs About GALVUS MET 50/850MG TABLET
Q: What is GALVUS MET 50/850MG TABLET used for?
A: GALVUS MET 50/850MG TABLET is a combination medication containing vildagliptin and metformin. It is used to manage type 2 diabetes mellitus by controlling blood sugar levels. Vildagliptin works by inhibiting the enzyme DPP-4, which increases insulin release and decreases glucagon production, thereby improving blood sugar control. Metformin reduces glucose production in the liver and enhances insulin sensitivity. Together, they provide effective glycemic control when diet, exercise, or other oral antidiabetics are insufficient.
Q: Is Galvus Met safe for kidneys?
A: Galvus Met should be used cautiously in patients with kidney issues. Metformin can pose a risk of lactic acidosis (a rare but serious complication) in individuals with significant kidney impairment. Vildagliptin is generally well-tolerated, but it also requires dose adjustments in moderate kidney impairment. Kidney function should be regularly monitored during treatment, especially in older adults or those with a history of kidney disease. If kidney function declines, the doctor may adjust the dosage or discontinue the medication.
Q: Is Galvus Met better than metformin?
A: Galvus Met combines metformin with vildagliptin, making it more effective for individuals who need dual therapy to control blood sugar levels. While metformin is the first-line treatment for type 2 diabetes, Galvus Met may offer better glycemic control by targeting different mechanisms. However, the choice depends on the patient’s specific condition, tolerance, and treatment goals. Metformin alone may suffice for newly diagnosed patients or those with mild hyperglycemia, while Galvus Met may be better for those requiring additional blood sugar control.
Q: What are the side effects of Galvus Met Tablet?
A: The most common side effects of taking GALVUS MET TABLET are nausea, vomiting, stomach pain, headache, low blood sugar, and diarrhea. Contact your doctor if any of the symptoms worsen.
Q: Does Galvus Met increase weight?
A: Galvus Met is generally weight-neutral, meaning it does not cause significant weight gain or loss. Vildagliptin does not promote weight gain, and metformin may even help with slight weight reduction by improving insulin sensitivity. This makes Galvus Met a good option for overweight or obese individuals with type 2 diabetes.
Q: Can Galvus Met cure diabetes?
A: Galvus Met does not cure diabetes; it helps manage blood sugar levels effectively. Type 2 diabetes is a chronic condition that requires long-term lifestyle changes, medications, and regular monitoring. Galvus Met can help prevent complications and improve quality of life when used consistently alongside diet and exercise.
Q: Does Galvus Met cause acidity?
A: Galvus Met may cause gastrointestinal symptoms, including acidity or a feeling of heartburn, primarily due to metformin. Taking the medication with food or switching to an extended-release formulation may reduce these symptoms. Persistent acidity should be discussed with a doctor to rule out other causes or adjust the treatment.
Q: Can Galvus Met cause constipation?
A: Constipation is not a common side effect of Galvus Met, but it may occur in some individuals. Metformin more commonly causes diarrhea or loose stools, while vildagliptin does not typically affect bowel movements. If constipation occurs, it is usually mild and can be managed with dietary changes, increased water intake, or fiber supplements. Persistent constipation should be evaluated by a doctor.
References
1. KD Tripathi MD. Hormones and related drugs. Essentials of Medical Pharmacology. Seventh edition. New Delhi, May 2013. Page-274.
2. Paresh Ved and Samrat Shah. Evaluation of vildagliptin and fixed dose combination of vildagliptin and metformin on glycemic control and insulin dose over 3 months in patients with type 2 diabetes mellitus. March 2012. [Accessed on 30th June 2021] click here
3. Serge Halimi, Anja Schweizer, Biljana Minic, James Foley and Sylvie Dejage. Combination treatment in the management of type 2 diabetes: focus on vildagliptin and metformin as a single tablet. March 2008. [Accessed on 30th June 2021] click here
4. Novartis Pharma GmbH. Electronic Medicines Compendium (EMC) [Revised in August 2021] [Accessed on 30th June 2021] click here
5. Cipla Ltd. VYSOV-M Tablets (Vildagliptin + Metformin hydrochloride). [Revised in July 2020] [Accessed on June 30, 2021] click here
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