Introduction About FORGLYN FORTE RESPICAP

FORGLYN FORTE RESPICAP is a fixed-dose combination of formoterol and glycopyrronium which belongs to the group of medicines called bronchodilators. It is used in the management of breathing difficulty in patients with chronic pulmonary disease (COPD). Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that obstructs the regular airflow from the lungs causing breathing difficulty. Emphysema and chronic bronchitis are common conditions of COPD.

FORGLYN FORTE RESPICAP is not recommended for patients with asthma and potentially life-threatening conditions of COPD (chronic obstructive pulmonary disease). FORGLYN FORTE RESPICAP should be used with caution in patients with heart disease, high blood pressure, diabetes, thyroid disorder, epilepsy, urinary retention, and narrow-angle glaucoma.

FORGLYN FORTE RESPICAP is not recommended for patients with milk protein allergy. [GBNKEYWORD should be used with caution in pregnant women. It is not known whether FORGLYN FORTE RESPICAP passes through breast milk consult your doctor for advice.

The common side effects of FORGLYN FORTE RESPICAP are allergic reaction, hoarseness of voice, fast heart rate, headache, nausea, dizziness, cough & dry mouth. Consult your doctor if any of your symptoms get worse.

Uses Of FORGLYN FORTE RESPICAP

• Management of chronic pulmonary disease (COPD)

How FORGLYN FORTE RESPICAP Works

FORGLYN FORTE RESPICAP is an anti-asthmatic medicine that works by managing breathing difficulty. It has two medicines namely formoterol and glycopyrronium. Formoterol is a bronchodilator which actively produces relaxation to the smooth muscles in the airway managing constriction of smooth muscles and breathing difficulty.

Glycopyrronium is a muscarinic antagonist that blocks the receptors of the smooth muscles causing constriction producing dilation of the bronchial muscles and reducing the bronchial secretions. Thus FORGLYN FORTE RESPICAP collectively works by relaxation of smooth muscle and reducing bronchial secretion.

How to use FORGLYN FORTE RESPICAP

Take FORGLYN FORTE RESPICAP as advised by your physician. It is for inhalation use only. Do not crush, chew, or swallow the capsules. Do not miss any dose of FORGLYN FORTE RESPICAP. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Rinse your mouth with water after using FORGLYN FORTE RESPICAP to help reduce your chance of fungal infections.

Side Effects Of FORGLYN FORTE RESPICAP

How To Manage Side Effects

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.

Headache

Take some rest, in a quiet place avoid using user mobile phones and other electronic devices for a while. Drink enough amount of Water, dehydration may lead you to develop a headache. If the symptom does not improve, contact your doctor.

Nausea And Vomiting

Drink clear or ice-cold drinks. Eat light, bland foods. Avoid fried, greasy, or sweet foods.  Eat slowly and eat smaller, more frequent meals, drink gradually larger amounts of clear liquids, avoid solid food until the vomiting episode has passed, and take rest. If the symptom does not improve, contact your doctor.

Warning & Precautions

Pregnancy

Use with Caution

[GBNKEYWORD should be used with caution in pregnant women. Consult your doctor before taking it.

Breastfeeding

Consult your doctor

It is not known whether FORGLYN FORTE RESPICAP passes through breast milk. Consult your doctor before taking FORGLYN FORTE RESPICAP if you wish to breastfeed.

Driving and Using Machines

Use with Caution

Since dizziness, accommodation disorder, mydriasis, and blurred vision can occur with the use of FORGLYN FORTE RESPICAP. Do not drive or handle heavy machines if you experience side effects like dizziness, drowsiness, tiredness, or if you have blurred vision while taking GBNKEYWORD].

Alcohol

Contraindicated

Consumption of alcohol is not recommended during management with FORGLYN FORTE RESPICAP.

Kidney

Use with Caution

FORGLYN FORTE RESPICAP should be used with caution in patients with kidney disease, urinary retention, prostate problems, or difficulty passing urine. Consult your doctor before taking it.

Liver

Use with Caution

FORGLYN FORTE RESPICAP should be used with caution in patients with liver disease. Consult your doctor before taking it.

Allergy

Contraindicated

Do not take FORGLYN FORTE RESPICAP if you are allergic to glycopyrronium, formoterol or lactose.

Lungs

Contraindicated

FORGLYN FORTE RESPICAP is not recommended for patients with asthma and potentially life-threatening conditions of COPD (chronic obstructive pulmonary disease). Consult your doctor before taking it.

Heart Disease

Use with Caution

FORGLYN FORTE RESPICAP should be used with caution in patients with heart diseases such as coronary insufficiency, cardiac arrhythmias, and high blood pressure (hypertension). Consult your doctor before taking it.

Use In Pediatrics

Contraindicated

FORGLYN FORTE RESPICAP is not recommended for use in children. Consult your doctor before taking it.

Use In Geriatrics

Use with Caution

FORGLYN FORTE RESPICAP should be used with caution in elder patients aged above 75 years and older. Consult your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking FORGLYN FORTE RESPICAP, inform your doctor if you are taking any of the following medicine:

• medicines used to manage high blood pressure also known as beta-blockers Ex. propranolol, metoprolol, atenolol
• medicines used to manage fluid accumulation by increasing urine secretion Ex. furosemide
• medicines used to manage depression Ex selegiline, phenelzine, amitriptyline, imipramine
• medicines used to manage inflammation. Ex. prednisolone
• medicines used to manage bacterial infection Ex. erythromycin, clarithromycin, telithromycin
• medicines used to manage allergic reactions Ex. cetirizine
• medicines used to increase blood pressure Ex. phenylephrine, dopamine
• other medicines used to manage asthma and COPD such as Ex. tiotropium, aclidinium, umeclidinium, theophylline, salbutamol

B. Drug–food interactions:

Do not take FORGLYN FORTE RESPICAP if you are allergic to a substance containing milk protein(lactulose).

Overdosage:

If you or anyone else accidentally took more of FORGLYN FORTE RESPICAP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include nausea, vomiting, dizziness, blurred vision, eye pain, vision disturbances, eye redness, difficulties in passing urine, seizures, chest pain, abnormal blood pressure, irregular heartbeat, nervousness, headache, tremor, muscle cramps, sleep disturbances, metabolic acidosis, changes in blood potassium levels. Metabolic acidosis, cardiac arrest and even death may also occur.

Synopsis

More Information

• Keep FORGLYN FORTE RESPICAP out of reach from children
• Store at room temperature

FAQs About FORGLYN FORTE RESPICAP

Q: How and when should I take FORGLYN FORTE RESPICAP?

A: Take FORGLYN FORTE RESPICAP as advised by your physician. It is for inhalation use only. Do not miss any dose of FORGLYN FORTE RESPICAP. Your doctor will determine the correct dose and duration for you depending on your age, body weight, and disease condition.

Q: Can I take more of FORGLYN FORTE RESPICAP to manage my breathing difficulty immediately?

A: No, do not take additional doses of FORGLYN FORTE RESPICAP than recommended because it may cause serious side effects. If you or anyone else accidentally took more of FORGLYN FORTE RESPICAP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include seizures, angina, abnormal blood pressure, an abnormal heartbeat, nervousness, headache, tremor, dry mouth, palpitation, nausea, dizziness, fatigue, weakness, and sleeplessness. Hypokalaemia, cardiac arrest, and even death can occur.

Q: Can I use FORGLYN FORTE RESPICAP along with my other heart medicines?

A: FORGLYN FORTE RESPICAP should be used with caution in patients with heart diseases such as coronary insufficiency, cardiac arrhythmias, and high blood pressure (hypertension). Do not use FORGLYN FORTE RESPICAP without consulting your doctor. FORGLYN FORTE RESPICAP should not be used along with heart medicines such as atenolol and propranolol.

Q: Is it safe to use FORGLYN FORTE RESPICAP on my eyes?

A: No, FORGLYN FORTE RESPICAP is not safe for the eyes. When brought into contact with the eyes, it produces complications such as dilation of the pupil, increased ocular pressure, glaucoma, and other eye disorders. FORGLYN FORTE RESPICAP is intended for inhalation purposes only and should be used with caution in patients with narrow-angle glaucoma.

Patients should be informed about the symptoms of acute narrow-angle glaucoma, such as eye pain, discomfort, blurred vision, coloured images with red eyes, and corneal oedema. You should consult a physician immediately if any of these signs or symptoms develop.

Q: How long will FORGLYN FORTE RESPICAP take to manage my breathing difficulty?

A: FORGLYN FORTE RESPICAP produces bronchodilation within 5 minutes of inhalation, which lasts up to a maximum of 12 hours. FORGLYN FORTE RESPICAP works fast in managing breathing difficulties.

References

1. K.D. Tripathi Drugs for Cough and Bronchial Asthma, Drugs Acting on Central Nervous System Essentials of pharmacology seventh edition 2013, Page no- 386,223.

2. Dhungana, S., & Criner, G. J. Spotlight on glycopyrronium/formoterol fumarate inhalation aerosol in the management of COPD: design, development, and place in therapy. NCBI: National Library of Medicine, PubMed articles, August 2017. [Accessed on 28th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546727/

3. AstraZeneca UK Limited. Electronic Medicines Compendium (EMC). [Revised on February 2021] [Accessed on 28th May 2022] https://www.medicines.org.uk/emc/files/pil.12024.pdf

4. Cipla med. [Revised on July 2019] [Accessed on 28th May 2022] https://www.ciplamed.com/print-product-pdf/44395