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Introduction About FOLSAFE D CAPSULE
FOLSAFE D CAPSULE is a combination of Docosahexaenoic Acid (DHA), L Methylfolate, Methylcobalamin, and Pyridoxal 5 Phosphate which belongs to the group of medicines called Omega 3 Fatty Acids, and Vitamins, respectively. It is used to manage spontaneous miscarriage, recurrent abortion, intrauterine growth restriction (IUGR), pre-eclampsia (potentially dangerous pregnancy complication), placental abruption (complete/partial separation of placenta), and pre-term labour in pregnant women.
FOLSAFE D CAPSULE is not recommended for use in patients allergic to L Methylfolate, Methylcobalamin, Pyridoxal 5 Phosphate, and/or any other ingredients of this medicine. Before taking FOLSAFE D CAPSULE, inform your doctor if you have vitamin B12 deficiency, kidney diseases (such as renal failure), and/or liver diseases (such as hepatic impairment).
FOLSAFE D CAPSULE should be used with caution during pregnancy and in breastfeeding women. It is also advised to be used with caution in children and adolescents (aged below 18 years) and in elderly patients (aged above 70 years) after consulting your doctor.
The most common side effects of taking FOLSAFE D CAPSULE are fever, itching, rash, tingling/numbness sensation in joint, shortness of breath, and/or rapid weight gain. Consult your doctor if any of these symptoms worsens.
Uses Of FOLSAFE D CAPSULE
- It is used to manage spontaneous miscarriage, recurrent abortion, intrauterine growth restriction (IUGR), pre-eclampsia, placental abruption, and pre-term labour in pregnant women
How FOLSAFE D CAPSULE Works
FOLSAFE D CAPSULE helps to manage spontaneous miscarriage, recurrent abortion, intrauterine growth restriction, and pre-term labour, where docosahexaenoic acid works by optimizing brain and retinal maturation in the developing foetus and manages preterm birth during pregnancy, methylcarbylamine works by managing cardiac diseases and aids in maintaining proper size of the baby (during pregnancy) by lowering homocysteine (an amino acid which on excess production leads to cardiovascular disease), Pyridoxal 5 Phosphate works by managing cardio-vascular malformations in the developing baby, and L Methylfolate works by aiding in the growth of the baby by acting as a co-factor in the inactivation of bone damaging amino acids thus managing the occurrence of intrauterine growth restriction during pregnancy.
How to use FOLSAFE D CAPSULE
Take FOLSAFE D CAPSULE as advised by your physician. Swallow the medicine with the glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of FOLSAFE D CAPSULE
Common
- fever
- itching
- rash
- tingling/numbness sensation in joint
- shortness of breath
- rapid weight gain
- signs of polycythaemia (increased number of red blood cells in body) such as headache, blurred vision, tiredness
- signs of hypokalaemia (low potassium level in blood) such as constipation, heart palpitations, extreme tiredness
Uncommon
- indigestion
- diarrhoea
- nausea
- belching
- unpleasant taste
Rare
Stop taking FOLSAFE D CAPSULE and contact your doctor if you experience any of the following side effects:
- increased risks of bleeding
How To Manage Side Effects
Skin rash Or Itching
Avoid itching harshly or scratching the site of itching. Keep moisturising the itchy skin regularly. Use gentle creams, lotions, or gels that soothe, and cool the skin. Avoid using soaps on the itchy skin. Wear the loose clothing.
Warning & Precautions
Pregnancy
Use with CautionFOLSAFE D CAPSULE should be used with caution in pregnant women. Consult and inform your doctor before taking the medicine.
Breastfeeding
Use with CautionFOLSAFE D CAPSULE should be used with caution in breastfeeding women. Consult your doctor before taking the medicine.
Driving and Using Machines
Use with CautionDo not drive or operate machines if FOLSAFE D CAPSULE affects your ability to drive or operate machines. Consult your doctor before taking the medicine.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking FOLSAFE D CAPSULE as it may decrease the effect of the medicine.
Kidney
Use with CautionFOLSAFE D CAPSULE should be used with caution in patients with kidney problems such as renal failure. Consult your doctor before taking the medicine.
Liver
Use with CautionFOLSAFE D CAPSULE should be used with caution in patients with liver diseases such as liver impairment. Consult your doctor before taking the medicine.
Allergy
ContraindicatedFOLSAFE D CAPSULE is not recommended for use if you are allergic to L Methylfolate, Methylcobalamin, Pyridoxal 5 Phosphate, or any of the other ingredients of this medicine. Consult your doctor before taking the medicine.
Others
Before taking FOLSAFE D CAPSULE, inform your doctor if you:
- have vitamin B12 deficiency
Use in Paediatrics
FOLSAFE D CAPSULE should be used with caution in children and adolescents (aged below 18 years). Consult your doctor before taking the medicine.
Use in Geriatrics
FOLSAFE D CAPSULE should be used with caution in elderly patients (aged above 60 years). Consult your doctor before taking.
Interactions
A. Drug-Drug Interactions
Before taking FOLSAFE D CAPSULE, inform your doctor, if you are taking any of the following medicine:
- anticonvulsants (medicines used to manage convulsions) Ex. carbamazepine, fosphenytoin, phenytoin, phenobarbital, primidone, valproic acid, valproate, lamotrigine, diavalproex sodium, topiramate, gabapentin, pregabalin, levetiracetam, tiagabine, zonisamide
- medicines used to manage parasitic infections (Ex. pyrimethamine)
- levodopa (medicine used to manage brain disorders)
- antibiotics (medicines used to manage bacterial infections) Ex. penicillin, amoxycillin, trimethoprim
- cholestyramine, colchicines, colestipol (medicines used to lower blood cholesterol levels)
- metformin (medicine used to control blood sugar levels)
- para-aminosalicylic acid (medicine used to manage tuberculosis)
- potassium chloride (medicine used to manage low potassium levels)
- nitrous oxide (medicine used for general anaesthesia, procedural sedation)
- methotrexate (medicine used to manage cancer)
- sulfasalazine (medicine used to manage inflammation)
- methylprednisone (medicine used to manage pain and swelling)
- NSAIDs (medicines used to manage pain, inflammation, and fever) Ex. ibuprofen
- pancreatic enzymes (medicines used to manage malabsorption syndrome due pancreatic problems) Ex. pancrelipase, pancratin
- triamterene (medicine used to manage high blood pressure)
- warfarin (medicine used to delay blood clotting)
Overdosage:
If you or anyone else accidentally takes too much of FOLSAFE D CAPSULE, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Docosahexaenoic Acid(DHA), L Methylfolate, Methylcobalamin, and Pyridoxal 5 Phosphate |
| Pharmacological Category | : | Omega 3 Fatty Acids, and Vitamins |
| Therapeutic Indication | : | Prevent spontaneous miscarriage, recurrent abortions, intrauterine growth restriction (IUGR), pre-eclampsia, placental abruption, or pre-term labour |
| Dosage Forms | : | Capsule |
More Information
- Keep the medicine out of reach in children
- Store FOLSAFE D CAPSULE at room temperature
FAQs About FOLSAFE D CAPSULE
Q. What is FOLSAFE D CAPSULE used for?
A. FOLSAFE D CAPSULE is used to manage spontaneous miscarriage, recurrent abortions, intrauterine growth restriction (IUGR), pre-eclampsia, placental abruption, and/or pre-term labour in women during pregnancy.
Q. What happens if you take more FOLSAFE D CAPSULE than your required dose?
A. If you or anyone else accidentally takes too much of FOLSAFE D CAPSULE, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.
Q. What are the side effects of FOLSAFE D CAPSULE?
A. The most common side effects of taking FOLSAFE D CAPSULE are fever, itching, rash, tingling/numbness sensation in joint, shortness of breath, and/or rapid weight gain. Consult your doctor if any of these symptoms worsens.
Q. How FOLSAFE D CAPSULE works?
A. FOLSAFE D CAPSULE helps to manage spontaneous miscarriage, recurrent abortion, intrauterine growth restriction, and pre-term labour, where docosahexaenoic acid works by optimizing brain and retinal maturation in the developing foetus and manages preterm birth during pregnancy, methylcarbylamine works by managing cardiac diseases and aids in maintaining proper size of the baby (during pregnancy) by lowering homocysteine (an amino acid which on excess production leads to cardiovascular disease), Pyridoxal 5 Phosphate works by managing cardio-vascular malformations in the developing baby, and L Methylfolate works by aiding in the growth of the baby by acting as a co-factor in the inactivation of bone damaging amino acids thus managing the occurrence of intrauterine growth restriction during pregnancy.
Q. Is it safe to drink alcohol while taking FOLSAFE D CAPSULE?
A. Avoid consumption of alcohol while taking FOLSAFE D CAPSULE since it may reduce the effect of the medicine and might caught undesirable effects. Consult your doctor before taking the medicine.
References
1. J. L. Jameson, A. S. Fauci, D. L. Kasper, S. L. Hauser, D. L. Longo, J. Loscalzo. Screening and Prevention of Diseases, Megaloblastic Anaemia. Harrison’s Principles of Internal Medicine. Twentieth edition. 2018. Page – 25, 702.
2. A S M Al Amin, Vikas Gupta. Vitamin B12 (Cobalamin). NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls [Internet]. June 2022. [Accessed on 20th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK559132/
3. Bethesda. Omega-3 Fatty acids. NIH National Library of Medicine. National Centre for Biotechnology Information. April 2017. [Accessed on 20th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK548910/
4. Karin Yurko-Mauro, Dominik D. Alexander, Mary E. Van Elswyk. Docosahexaenoic Acid and Adult Memory: A Systematic Review and Meta-Analysis. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. March 2015. [Accessed on 20th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364972/
5. Centaur Pharma. Nuring Active Tablets. [Revised in January 2022] [Accessed on 20th September 2022] https://www.centaurpharma.com/downloads/2022/neurology/NURING%20ACTIVE.pdf
6. Atlantis Formulations Pvt. Ltd. Metlong DHA Capsules. [Accessed on 20th September 2022] http://atlantisformulations.com/soft-caps
Useful Diagnostic Tests
- Pelvic Exam
- Ultrasound
Author Details
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
