Introduction About FOLIJON CAPSULE

FOLIJON CAPSULE is a combination of Docosahexaenoic Acid (DHA), Folic Acid, Methylcobalamin, and Pyridoxine which belongs to the group of medicines called Omega 3 fatty acids and Vitamins, respectively. It is used to provide nourishment to the foetus for its healthy development during pregnancy.

FOLIJON CAPSULE is not recommended for use if you are allergic to folic acid, and/or any other ingredients of this medicine. It is also not recommended for use in patients suffering from unmanageed vitamin B12 deficiency (such as certain anaemias and in lifelong vegetarians), pernicious anaemia (a form of anaemia caused by lack of vitamin B12), and/or malignant (cancerous) disease.

Before taking FOLIJON CAPSULE, inform your doctor if you have liver disease (such as chronic liver disease). The medicine is advised to be used with caution in pregnant & breastfeeding women.

FOLIJON CAPSULE should be used with caution in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 60 years and above) after consulting the doctor.  

The most common side effects associated with the use of FOLIJON CAPSULE are fever, itching, rash, tingling/numbness sensation in joint, shortness of breath, and/or rapid weight gain. Consult your doctor if any of these symptoms worsens.

Uses Of FOLIJON CAPSULE

• Provides nourishment for the healthy development of foetus during pregnancy

How FOLIJON CAPSULE Works

FOLIJON CAPSULE helps in foetal development by providing nourishment to the foetus where docosahexaenoic acid optimizes brain and retinal maturation in developing foetus, folic acid helps in promoting growth in foetus by acting as a co-factor for the inactivation of bone damaging amino acids, methylcobalamin manages occurrence of cardiac disease in developing foetus by lowering homocysteine (an amino acid that cause cardiovascular disease on excess production), and pyridoxine helps in the ideal functioning of brain and nervous system in the developing foetus by playing an essential role in the synthesis of myelin sheath (protective covering on the nerves) and certain neurotransmitters (chemical messengers that help in nerve conduction) thus managing brain impairment and providing nourishment to the developing foetus during pregnancy.

How to use FOLIJON CAPSULE

Take FOLIJON CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of FOLIJON CAPSULE

How To Manage Side Effects

Itching

Avoid itching harshly or scratching the site of itching. Keep moisturising the itchy skin regularly. Use gentle creams, lotions, or gels that soothe, and cool the skin. Avoid using soaps on the itchy skin. Wear the loose clothing.

Nausea:

Try to take FOLIJON CAPSULE with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if symptom gets worse.

Indigestion:

Try to have smaller and more frequent meals and drink slowly. Reduce consumption of coffee, cola, tea, or alcohol and lose weight if you are obese.  Try to avoid smoking and don’t have rich, fatty or spicy foods. Consult your doctor and inform if the symptom does not improve.

Diarrhea:

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor and inform them if the symptom gets worse.

Warning & Precautions

Pregnancy

FOLIJON CAPSULE should be used with caution if you are pregnant or planning to become pregnant. Consult and inform your doctor before taking the medicine.

Breastfeeding

FOLIJON CAPSULE should be used with caution in breastfeeding women. Consult your doctor before taking the medicine.

Alcohol

Avoid consumption of alcohol while taking FOLIJON CAPSULE.

Kidney

FOLIJON CAPSULE should be used with caution in patients undergoing kidney dialysis. Consult your doctor before taking the medicine.

Liver

FOLIJON CAPSULE should be used with caution in patients with advanced chronic liver disease. Consult your doctor before taking the medicine.

Allergy

FOLIJON CAPSULE is not recommended for use if you are allergic to folic acid, or any of the other ingredients of this medicine. Consult your doctor before taking the medicine.

Interactions

A.Drug-Drug Interactions

Before taking FOLIJON CAPSULE, inform your doctor, if you are taking any of the following medicine:

• antiepileptics (medicines used to manage epilepsy) Ex. phenytoin, phenobarbital, primidone, sodium valproate, carbamazepine
• antibacterials (medicines used to manage infections) Ex. trimethoprim, chloramphenicol, cotrimoxazole
• sulfasalazine (medicine used to manage ulcerative colitis, Crohn’s disease, or rheumatoid arthritis)
• methotrexate (medicines used to manage Crohn’s disease, psoriasis, or rheumatoid arthritis)
• lithium (medicine used to manage mental illness)
• triamterene (medicine used to manage high blood pressure)
• medicines used to put you to sleep for an operation or to relieve pain while you are awake (Ex. butorphanol)
• aspirin (medicine used to manage pain relief or to thin the blood)

Overdosage:

If you or anyone else accidentally takes too much of FOLIJON CAPSULE, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep the medicine out of reach in children
• Store FOLIJON CAPSULE below 25°C

FAQs About FOLIJON CAPSULE

What are the side effects of FOLIJON CAPSULE?

The most common side effects associated with the use of FOLIJON CAPSULE are fever, itching, rash, tingling/numbness sensation in joint, shortness of breath, and/or rapid weight gain. Consult your doctor if any of these symptoms worsens.

What happens if you take more FOLIJON CAPSULE than your required dose?

If you or anyone else accidentally takes too much of FOLIJON CAPSULE, consult your doctor immediately or visit the nearby hospital for managing the overdose symptoms.

Who should avoid taking FOLIJON CAPSULE?

FOLIJON CAPSULE is not recommended for use if you are allergic to folic acid and/or any other ingredients of this medicine. It is also not recommended for use if you have an unmanageed vitamin B12 deficiency (such as certain anaemias and in lifelong vegetarians), pernicious anaemia (a form of anaemia caused by lack of vitamin B12), and/or malignant (cancerous) disease. Consult your doctor before taking the medicine.

How FOLIJON CAPSULE works?

FOLIJON CAPSULE helps in foetal development by providing nourishment to the foetus where docosahexaenoic acid optimizes brain and retinal maturation in developing foetus, folic acid helps in promoting growth in foetus by acting as a co-factor for the inactivation of bone damaging amino acids, methylcobalamin manages occurrence of cardiac disease in developing foetus by lowering homocysteine (an amino acid that cause cardiovascular disease on excess production), and pyridoxine helps in the ideal functioning of brain and nervous system in the developing foetus by playing an essential role in the synthesis of myelin sheath (protective covering on the nerves) and certain neurotransmitters (chemical messengers that help in nerve conduction) thus managing brain impairment and providing nourishment to the developing foetus during pregnancy. 

Is FOLIJON CAPSULE safe to use in pregnant and breastfeeding women?

Yes, FOLIJON CAPSULE can be used but with caution during pregnancy and in women planning for pregnancy and also in breastfeeding women. Consult your doctor before taking the medicine.

What if I forget to take FOLIJON CAPSULE dose?

If you forgot to take FOLIJON CAPSULE dose, take it as early as possible. Do not double the dose to make up for the missed dosage. Consult your doctor before taking the medicine.

References

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2. A S M Al Amin, Vikas Gupta. Vitamin B12 (Cobalamin). NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls [Internet]. June 2022. [Assessed on 9th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK559132/

3. Sanjay Basak, Rahul Mallick, and Asim K. Duttaroy. Maternal Docosahexaenoic Acid Status during Pregnancy and Its Impact on Infant Neurodevelopment. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. December 2020. [Accessed on 9th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759779/

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5. NourEldin R. Abosamak; Vikas Gupta. Vitamin B6 (Pyridoxine). NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls [Internet]. May 2022. [Accessed on 9th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK557436/

6. Bethesda. Omega-3 Fatty Acids. NIH National Library of Medicine. National Centre for Biotechnology Information. April 2017. [Accessed on 9th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK548910/

7. Zoe Boyer-Diaz, Joan Carles Domingo, Estefanía De Gregorio, Nicolò Manicardi, Peio Aristu-Zabalza, Begoña Cordobilla, Laia Abad-Jordà, Martí Ortega-Ribera, Anabel Fernández-Iglesias, Montserrat Marí, Jaime Bosch, Jordi Gracia-Sancho. A Nutraceutical Rich in Docosahexaenoic Acid Improves Portal Hypertension in a Preclinical Model of Advanced Chronic Liver Disease. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. October 2019. [Assessed on 9th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835927/

8. Karin Yurko-Mauro, Dominik D. Alexander, Mary E. Van Elswyk. Docosahexaenoic Acid and Adult Memory: A Systematic Review and Meta-Analysis. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. March 2015. [Assessed on 9th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364972/

9. Innovative Pharma. Folizen Forte Tablets. [Accessed on 9th September 2022] https://www.innovativepharma.in/product/folizen-forte-tablets/

10. Accord. Electronic Medicines Compendium (EMC). [Revised in May 2019] [Assessed on 9th September 2022] https://www.medicines.org.uk/emc/files/pil.5788.pdf