Introduction About FLUTENSE CAPSULE

FLUTENSE CAPSULE contains Flupirtine which belongs to a group of medicines called Nonopioid, Non-NSAID analgesics. It is used in the management of acute and chronic pain (such as primary headache, tumor pain, menstrual cramps, pain after traumatologic/orthopaedic operations and injuries and painful increased muscle tone of the posture and motor muscles).  

FLUTENSE CAPSULE is not recommended for use in patients with liver problems. Before taking FLUTENSE CAPSULE, inform your doctor if you have kidney disease, myasthenia gravis, had or have a history of tinnitus (ringing in the ears) or if you are allergic to Flupirtine. FLUTENSE CAPSULE is not recommended for use in pregnant and breast-feeding women unless clearly advised by the doctor.

FLUTENSE CAPSULE is not recommended for use in children and adolescents (below 18 years of age) unless deemed necessary and it should be used with caution in elderly patients, especially in patients with kidney problems. The most common side effects of taking FLUTENSE CAPSULE are fatigue, dizziness, heartburn, nausea, vomiting, dry mouth, constipation and diarrhea. Consult your doctor if any of the side effects worsen.

Uses Of FLUTENSE CAPSULE

• Manage acute and chronic pain (such as primary headache, tumor pain, menstrual cramps, pain after traumatologic/orthopaedic operations and injuries and painful increased muscle tone of the posture and motor muscles)

How FLUTENSE CAPSULE Works

FLUTENSE CAPSULE works by managing the transmission of pain signals by blocking neuronal excitability and reducing the calcium influx into the cells that is responsible for the sense of pain and inflammation produced at the site of injury and damage and hence it is useful in providing relief from pain, including that is associated with muscle tension.

How to use FLUTENSE CAPSULE

Take FLUTENSE CAPSULE as advised by your physician. Swallow the medicine with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age and body weight.

Side Effects Of FLUTENSE CAPSULE

How To Manage Side Effects

Constipation

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. If the symptom does not improve, consult your doctor.

Diarrhea

Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to manage diarrhea and consult your doctor if the symptom gets worse.

Dry Mouth

Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.

Headache

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.

Nausea And Vomiting

Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve.

Warning & Precautions

Pregnancy

Monitoring required

FLUTENSE CAPSULE is not recommended during pregnancy unless considered clearly necessary. Consult your doctor before taking FLUTENSE CAPSULE.

Breastfeeding

Monitoring required

FLUTENSE CAPSULE is not recommended in breastfeeding women unless considered clearly necessary. Consult your doctor before taking FLUTENSE CAPSULE.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizzy or sleepy after taking FLUTENSE CAPSULE.

Alcohol

Consult your doctor

Avoid consuming alcohol while taking FLUTENSE CAPSULE as it may increase the risk of liver problems.

Kidney

Use with Caution

FLUTENSE CAPSULE should be used with caution in patients with kidney diseases. Consult your doctor for advice before taking FLUTENSE CAPSULE.

Liver

Contraindicated

FLUTENSE CAPSULE is not recommended for use in patients with liver problems. Consult your doctor for advice before taking FLUTENSE CAPSULE.

Allergy

Contraindicated

FLUTENSE CAPSULE is not recommended for use if you are allergic to flupirtine.

Use In Pediatrics

Contraindicated

FLUTENSE CAPSULE is not recommended for use in children and adolescents (below 18 years of age) unless deemed necessary. Consult your child’s doctor for advice.

Use In Geriatrics

Use with Caution

FLUTENSE CAPSULE should be used with caution in elderly patients, especially in patients with any kidney problems. Consult your doctor for advice before taking FLUTENSE CAPSULE.

Interactions

A. Drug-Drug interactions:

Before taking FLUTENSE CAPSULE, inform your doctor, if you are taking any of the following medicines:

• Medicines that manage or manages blood clot (Ex. warfarin, dicumarol)
• Paracetamol (used to reduce fever and inflammation)
• Carbamazepine (used to manage epilepsy)
• Diazepam (used to manage anxiety and alcohol withdrawal)

Overdosage:

If you or anyone else accidentally takes too much of FLUTENSE CAPSULE, consult your doctor immediately or visit the nearby hospital.  

Synopsis

More Information

FAQs About FLUTENSE CAPSULE

Q: What is FLUTENSE CAPSULE used for?

A: FLUTENSE CAPSULE is used in the management of acute and chronic pain (such as primary headache, tumor pain, menstrual cramps, pain after traumatologic/orthopaedic operations and injuries and painful increased muscle tone of the posture and motor muscles).

Q: What common side effects are seen with FLUTENSE CAPSULE?

A: The most common side effects of taking [GBNKEYWORD are fatigue, dizziness, heartburn, nausea, vomiting, dry mouth, diarrhoea, constipation, diarrhea, stomach upset, bloating and pain, loss of appetite, tremor, headache, increased sweating, sleep problems and restlessness. Consult your doctor if any of the side effects worsen.

Q: How does FLUTENSE CAPSULE work?

A: FLUTENSE CAPSULE works by managing the transmission of pain signals by blocking neuronal excitability and reducing the calcium influx into the cells that is responsible for the sense of pain and inflammation produced at the site of injury and damage, and hence it is useful in providing relief from pain, including that is associated with muscle tension.

Q: Can FLUTENSE CAPSULE be used in pregnant women?

A: FLUTENSE CAPSULE is not recommended for use in pregnant women unless clearly advised by the doctor. Consult your doctor before taking FLUTENSE CAPSULE if you are pregnant or planning to get pregnant.

Q: Is FLUTENSE CAPSULE safe to use in patients with kidney diseases?

A: FLUTENSE CAPSULE should be used with caution in patients with kidney diseases. Your doctor may regularly monitor your kidney function before and during management with FLUTENSE CAPSULE to manage the risk of kidney damage. Consult your doctor for advice before taking FLUTENSE CAPSULE.

References

1. KD. Tripathi. Opioid Analgesics and Antagonists. Essentials of medical pharmacology. Seventh edition. 2013. Page – 469- 486.

2. Harish S, Bhuvana K, Bengalorkar GM, Kumar T. Flupirtine: Clinical pharmacology. Journal of Anaesthesiology and Clinical Pharmacology. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. June 2012. [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339720/

3. Singal R, Gupta P, Jain N, Gupta S. Role of flupirtine in the treatment of pain - chemistry and its effects. Journal of Clinical medicine. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. June 2012. [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557425/

4. Kim Lawson. Pharmacology and clinical applications of flupirtine: Current and future options. World Journal of Pharmacology. January 2019. [Accessed on 21st June 2022] https://www.wjgnet.com/2220-3192/full/v8/i1/1.htm

Useful Diagnostic Tests

• Liver function test
• Kidney function test