Introduction About FLUCOZEST 0.5% GEL

FLUCOZEST 0.5% GEL contains Fluconazole which belongs to the group of medicines called Antifungal agents. It is used to manage dermal fungal infections (dermatomycosis) caused by dermatophytes, yeasts, and moulds such as tinea pedis (athlete's foot), tinea corporis (ring worm), tinea cruris (fungal sweat rash), and tinea versicolor.

Tinea pedis (athlete's foot) is a fungal infection that begins between toes generally in people whose feet remain sweaty. It is characterized by symptoms such as scaly rashes, itching, stinging, and burning between toes. Tinea corporis (ring worm) is a fungal infection causing circular itchy rashes with clearer skin in the middle, resembling a ring.

Tinea cruris (fungal sweat rash) or jock itch is a fungal infection characterized by red and itchy rashes in the moist areas of the body such as groin. Tinea versicolor is a fungal infection that is characterized by abnormal skin pigmentation such as light and dark patches at the affected area.

Before using FLUCOZEST 0.5% GEL inform your doctor if you have kidney, liver, heart, and lung problems. FLUCOZEST 0.5% GEL is not recommended to use among women who are pregnant or breastfeeding. FLUCOZEST 0.5% GEL can be used in children and adolescents. Consult with your child’s doctor before using it for your child.

There is no information on the use of FLUCOZEST 0.5% GEL in elderly patients. Consult with your doctor before using. The most common side effects of using FLUCOZEST 0.5% GEL are skin rash, irritation, dryness or cracking of the surrounding area, itchiness and burning sensation at the site of application. Contact your doctor if any of the above symptoms worsen or persists.

Uses Of FLUCOZEST 0.5% GEL

Manages dermal fungal infections such as:

• Tinea pedis
• Tines corporis
• Tinea cruris
• Tinea versicolor
• Candidiasis

How FLUCOZEST 0.5% GEL Works

FLUCOZEST 0.5% GEL helps in manage fungal infection where Fluconazole inhibits the synthesis of certain compounds that are essential components of the fungal cell membrane. Moreover, it also impairs various important biological processes inside the fungal cell body required for its survival, thereby killing the killing the fungal cell bodies.

How to use FLUCOZEST 0.5% GEL

Always apply FLUCOZEST 0.5% GEL as directed by your physician. It is for external use only. Clean and dry the affected area and apply a thin layer of FLUCOZEST 0.5% GEL to the affected area. Wash your hands before and after application. Your doctor will decide the correct dose and duration of FLUCOZEST 0.5% GEL for you depending on your age, body weight, and disease condition.

Side Effects Of FLUCOZEST 0.5% GEL

How To Manage Side Effects

Skin irritation:

Hot water makes your skin irritated, so avoid taking hot showers. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. To soothe and hydrate the irritated skin, apply moisturizers. Contact your doctor if irritation worsens.

Warning & Precautions

Pregnancy

FLUCOZEST 0.5% GEL is not recommended for use in pregnant women. Consult your doctor before using it.

Breastfeeding

FLUCOZEST 0.5% GEL is not recommended to use in breastfeeding women. Consult your doctor before using it.

Driving and Using Machines

FLUCOZEST 0.5% GEL is unlikely to affect the ability to drive or use machines.

Allergy

Do not use FLUCOZEST 0.5% GEL if you are allergic to Fluconazole, or any of the other ingredients of this medicine.

Interactions

A. Drug-Drug interactions:

Before using FLUCOZEST 0.5% GEL, inform your doctor about all the medicines you use, including prescription and over-the-counter medications, as well as herbal supplements.

Overdosage

If you or anyone else use more or accidentally ingests or applies too much of FLUCOZEST 0.5% GEL, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep FLUCOZEST 0.5% GEL out of reach in children
• Store FLUCOZEST 0.5% GEL at a temperature below 30°C

FAQs About FLUCOZEST 0.5% GEL

What is FLUCOZEST 0.5% GEL and why is it prescribed?

FLUCOZEST 0.5% GEL contains Fluconazole which belongs to the group of medicines called Antifungal agents. It is used to manage dermal fungal infections (dermatomycosis) caused by dermatophytes, yeasts, and moulds such as tinea pedis (athlete's foot), tinea corporis (ring worm), tinea cruris (fungal sweat rash), and tinea versicolor.

How and when FLUCOZEST 0.5% GEL should be used?

Always apply FLUCOZEST 0.5% GEL as directed by your physician. It is for external use only. Clean and dry the affected area and apply a thin layer of FLUCOZEST 0.5% GEL to the affected area. Wash your hands before and after application. Your doctor will decide the correct dose and duration of FLUCOZEST 0.5% GEL for you depending on your age, body weight, and disease condition.

What if I forget to use a dose of FLUCOZEST 0.5% GEL?

If you forget a dose of FLUCOZEST 0.5% GEL, use it as soon as you remember. However, if it is almost time for the next dose, then skip the missed dose of FLUCOZEST 0.5% GEL and apply the next scheduled dose at the prescribed time. Do not double the dose in order to make up for the missed one as this may increase the chances of developing side effects.

Is it safe to use FLUCOZEST 0.5% GEL in pregnancy and breastfeeding?

FLUCOZEST 0.5% GEL is not recommended to use among pregnant and breastfeeding women. Consult your doctor for more information before using it.

Can I stop using FLUCOZEST 0.5% GEL if I feel my condition improved?

No, do not stop using FLUCOZEST 0.5% GEL without consulting your doctor even if you feel better or your condition is improved. Your symptoms may improve before the infection is completely managed. So, it is advised to continue the management for the prescribed duration to avoid the recurrence of the infection.

Is it safe to use FLUCOZEST 0.5% GEL in children and adolescents?

FLUCOZEST 0.5% GEL can be used in children and adolescents. Consult with your child’s doctor before using FLUCOZEST 0.5% GEL for your child.

Can FLUCOZEST 0.5% GEL cause skin irritation?

Yes. FLUCOZEST 0.5% GEL may cause skin irritation. Hot water makes your skin irritated, so avoid taking hot showers. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. To soothe and hydrate the irritated skin, apply moisturizers. Contact your doctor if irritation worsens.

References

1. KD. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 794.

2. Ameish Govindarajan, Karlyle G. Bistas, Curtis J. Ingold, Ayham Aboeed. Fluconazole. NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls. June 2022. [Accessed on 27th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK537158/

3. Suvarna Shelke, Amol Deshmukh, Prajakta Shinde, Pravin Dighe. Formulation and Evaluation of Fluconazole Gel for Topical Application. Asian Journal of Pharmaceutical Research and Development. Research gate. June 2021 [Accessed on 27th October 2022] https://www.researchgate.net/publication/354269436_Formulation_and_Evaluation_of_Fluconazole_Gel_for_Topical_Application

4. Pharmaline. Fluconazole. [Revised in February 2014] [Accessed on 27th October 2022] https://medicarcp.com/website/pdf/pils/5217%20-%20en.pdf

5. MIMS. Fluconazole. [Accessed on 27th October 2022] https://www.mims.com/philippines/drug/info/flusum?type=full

6. Leeford Healthcare. Flumet Gel (Fluconazole). [Accessed on 27th October 2022] https://www.leeford.in/product/1174/flumet-gel

7. Drugbank. Fluconazole. [Revised in October 2022] [Accessed on 27th October 2022] https://go.drugbank.com/drugs/DB00196