FLEMICLAV 375mg Tablet 10's
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FLEMICLAV 375MG TABLET is used to manage bacterial infections, including middle ear and sinus infections, respiratory tract infections, genital tract infections, urinary tract infections, skin and soft tissue infections such as dental infections, bone and joint infections, septic abortion, and abdominal infections. The symptoms of bacterial infection include fever, difficulty breathing, pus formation, and pain.
It contains a combination of medicines called Amoxicillin and Clavulanic acid, which belong to the group of medicines called Antibiotics. It works by preventing the growth of bacteria and helps clear up the infection.
FLEMICLAV 375MG TABLET is not recommended for use if you have liver problems or jaundice upon taking an antibiotic or amoxicillin-clavulanate. Before taking this medicine, inform your doctor if you are suffering from a hepatic impairment, liver disease, renal impairment, kidney disease, glandular fever, or are unable to pass water properly.
FLEMICLAV 375MG TABLET should be used with caution in pregnant and breastfeeding women only if it is considered necessary. It should be used with caution in children (aged below 12 years) and elderly patients (above 50 years).
The common side effects associated with the use of FLEMICLAV 375MG TABLET are diarrhea, thrush (fungal infection in the vagina, skin folds, or mouth), nausea, and vomiting. Contact your doctor immediately if any of the symptoms worsen.
Uses Of FLEMICLAV 375MG TABLET
How FLEMICLAV 375MG TABLET Works
FLEMICLAV 375MG TABLET helps in managing bacterial infection where amoxicillin is a penicillin that works by inhibiting the enzymes that help in the synthesis of the integral structural component of the bacterial cell wall whereas clavulanic acid is a beta-lactam (structurally related to penicillin) that works by inactivating an enzyme, namely beta-lactamase, thereby managing the inactivation of amoxicillin.
How to use FLEMICLAV 375MG TABLET
- Take this medicine as advised by your physician.
- For Tablet, Capsule: Swallow the tablet with a glass of water. Do not crush or chew the medicine.
- For Dispersible Tablet: Disperse FLEMICLAV 375MG TABLET in the specified quantity of water as mentioned in the label.
- Consume the mixture immediately after reconstitution.
- Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
Side Effects Of FLEMICLAV 375MG TABLET
Common Side Effects of FLEMICLAV 375MG TABLET:
- Diarrhoea
- thrush (fungal infection in the vagina, skin folds, or mouth)
- nausea
- vomiting
Stop taking FLEMICLAV 375MG TABLET and contact your doctor if you experience any of the following side effects:
- inflammation of the liver (hepatitis), jaundice
Warning & Precautions
Pregnancy
Monitoring requiredFLEMICLAV 375MG TABLET should be used with caution in pregnant women only if it is considered clearly necessary.
Breastfeeding
Use with CautionFLEMICLAV 375MG TABLET should be used with caution in breastfeeding women.
Driving and Using Machines
ContraindicatedDo not drive or operate machines while taking if you feel unwell.
Kidney
Use with CautionFLEMICLAV 375MG TABLET should be used with caution in patients with renal impairment or kidney problems.
Liver
Consult your doctorFLEMICLAV 375MG TABLET is not recommended for use if you have ever had liver problems or jaundice upon taking an antibiotic or amoxicillin-clavulanate. It should be used with caution in patients with hepatic impairment or liver problems.
Allergy
ContraindicatedDo not take FLEMICLAV 375MG TABLET if you are allergic to amoxicillin, clavulanic acid, penicillin, any antibiotic, or any other ingredients of this medicine.
Use In Pediatrics
Use with CautionFLEMICLAV 375MG TABLET should be used with caution in children (below 12 years).
Use In Geriatrics
Use with CautionFLEMICLAV 375MG TABLET should be used with caution in elderly patients (above 50 years).
Others
Before taking FLEMICLAV 375MG TABLET, inform your doctor if you:
- have glandular fever
- are unable to pass water properly
Interactions
A. Drug-Drug Interactions
Before taking FLEMICLAV 375MG TABLET, inform your doctor if you are taking any of the following medicines:
- allopurinol, probenecid (medicine used to manage gout)
- warfarin (medicine used to inhibit blood clotting)
- methotrexate (medicine used to manage rheumatic diseases or certain cancers)
- mycophenolate mofetil (a medicine used to manage the organ rejection after organ transplant)
- contraceptives (medicines used to manage conception)
Overdosage:
If you or anyone else accidentally takes too much of FLEMICLAV 375MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are gastrointestinal symptoms (including heartburn, indigestion, bloating, and constipation).
Synopsis
| Drug | : | Amoxicillin, Clavulanic Acid |
| Pharmacological Category | : | Antibiotics |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet, Capsule, Sachet, Dispersable tablet |
FAQs About FLEMICLAV 375MG TABLET
Q: What FLEMICLAV 375MG TABLET is used for?
A: FLEMICLAV 375MG TABLET is used for managing bacterial infections including middle ear & sinus infections, respiratory tract infections, genital tract infections, urinary tract infections, skin & soft tissue infections such as dental infections, bone & joint infections, septic abortion (any abortion complicated by uterine infection), and abdominal infections.
Q: What happens if you take more FLEMICLAV 375MG TABLET than your required dose?
A: If you or anyone else accidentally takes too much of FLEMICLAV 375MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are gastrointestinal symptoms (including heartburn, indigestion, bloating, and constipation).
Q: What side effects are seen with FLEMICLAV 375MG TABLET?
A: The common side effects associated with the use of FLEMICLAV 375MG TABLET are diarrhea, thrush (fungal infection in the vagina, skin folds, or mouth), nausea, and vomiting. Contact your doctor immediately if any of the symptoms worsen.
Q: Who should avoid taking FLEMICLAV 375MG TABLET?
A: Do not take FLEMICLAV 375MG TABLET if you are allergic to amoxicillin, clavulanic acid, penicillin, or any antibiotic. It is not recommended for use if you have liver problems or jaundice upon taking an antibiotic or amoxicillin-clavulanate.
Q: Is FLEMICLAV 375MG TABLET safe to use in children?
A: FLEMICLAV 375MG TABLET should be used with caution in children (below 12 years). Children (aged 6 years or below) should be managed with oral suspension or sachets containing amoxicillin and clavulanic acid. Consult your doctor before taking FLEMICLAV 375MG TABLET.
Q: How does FLEMICLAV 375MG TABLET work?
A: FLEMICLAV 375MG TABLET helps in managing bacterial infection where amoxicillin is a penicillin that works by inhibiting the enzymes that help in the synthesis of an integral structural component of the bacterial cell wall whereas clavulanic acid is a beta-lactam (structurally related to penicillin) that works by inactivating an enzyme, namely beta-lactamase, thereby managing the inactivation of amoxicillin.
Q: Is FLEMICLAV 375MG TABLET safe for kidneys?
A: FLEMICLAV 375MG TABLET should be used with caution in patients with renal impairment or kidney problems. Consult your doctor before taking it.
Q: How should I take FLEMICLAV 375MG TABLET?
A: For Tablet, Capsule:
Take FLEMICLAV 375MG TABLET as advised by your physician. Swallow the tablet with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse FLEMICLAV 375MG TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution.
Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
Q: What if I forget to take FLEMICLAV 375MG TABLET dose?
A: If you forgot to take FLEMICLAV 375MG TABLET dose, take it as early as possible. Avoid taking the next dose too soon. Wait for about 4 hours before taking the scheduled next dose. Consult your doctor before taking FLEMICLAV 375MG TABLET.
Q: When to stop taking FLEMICLAV 375MG TABLET?
A: Do not stop taking FLEMICLAV 375MG TABLET without thoroughly discussing it with your doctor until the management course is completed, even if you start feeling better. This is because if some bacteria survive due to incomplete medication, they may relapse into the infection.
Q: Is FLEMICLAV 375MG TABLET safe to use in liver patients?
A: FLEMICLAV 375MG TABLET is not recommended for use if you have liver problems or jaundice upon taking an antibiotic or amoxicillin-clavulanate. It should be used with caution in patients with hepatic impairment or liver problems. Consult your doctor before taking FLEMICLAV 375MG TABLET.
References
1. KD Tripathi. Beta-Lactam Antibiotics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 723.
2. Justin Evans, Maryam Hannoodee, and Micah Wittler. Amoxicillin Clavulanate. NIH National Library of Medicine. National Centre for Biotechnology Information. Stat Pearls [Internet]. December 2021. [Assessed on 7th October 2024] click here
3. Lek Pharmaceuticals d.d., Health Products Regulatory Authority (HPRA). [Revised in December 2014] [Assessed on 7th October 2024] click here
4. GSK group of companies. Augmentin. [Revised in December 2017] [Assessed on 7th October 2024] click here
5. Macleods Pharmaceuticals Ltd. Polyclav DS Tab. [Assessed on 7th October 2024] click here
6. Amoxicillin and Clavulanic acid. Micro Labs Ltd. [Assessed on 7th October 2024] click here
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