FENABRATE 145 Tablet 10's
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Introduction About FENABRATE 145 TABLET
FENABRATE 145 TABLET contains Fenofibrate, which belongs to the group of medicines called fibrates. It is used to lower the levels of fat (triglycerides) in the blood. FENABRATE 145 TABLET is used along with a low-fat diet, exercise, and weight loss to lower the levels of fat in the blood.
Fenofibrate works by lowering the levels of triglycerides and bad cholesterol (LDL) while raising the levels of good cholesterol (HDL).
FENABRATE 145 TABLET is not recommended for use in patients with severe liver problems, kidney problems, gallbladder problems, or pancreatitis. FENABRATE 145 TABLET is generally not recommended for use among pregnant and breastfeeding women.
The most common side effects of taking FENABRATE 145 TABLET may include diarrhea, stomach pain, wind (flatulence), feeling sick (nausea), being sick (vomiting), an increase in the levels of liver enzymes in the blood, and an increase in homocysteine. Contact your physician if any of the symptoms worsen.
Uses Of FENABRATE 145 TABLET
- It is used to lower the levels of fat (triglycerides) in the blood
How FENABRATE 145 TABLET Works
FENABRATE 145 TABLET works by lowering the levels of triglycerides, bad cholesterol (LDL), and total cholesterol while increasing the good cholesterol (HDL) level simultaneously.
How to use FENABRATE 145 TABLET
Take FENABRATE 145 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose, frequency, and duration for you depending upon your age, body weight, and disease condition.
Side Effects Of FENABRATE 145 TABLET
Common
- diarrhea
- stomach pain
- wind (flatulence)
- feeling sick (nausea)
- being sick (vomiting)
- elevated liver enzymes
- increase in homocysteine
Uncommon
- headache
- gallstones
- reduced sex drive
- red itchy rashes on the skin
- elevated creatinine levels
- symptoms of pancreatitis (inflammation of the pancreas leading to abdominal pain)
- thromboembolism, pulmonary embolism (blood clot in the lung causing chest pain and breathlessness), and deep vein thrombosis (blood clot in the leg causing pain, redness, or swelling)
- muscle pain or cramps, muscle inflammation, and weakness
Rare
- hair loss
- increase in urea levels
- increased sensitivity of the skin to sunlight, sun lamps, and sunbeds
- drop in hemoglobin (that carries oxygen in the blood) and white blood cells (shown in tests)
- stomach pain, and itching
Stop taking FENABRATE 145 TABLET and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions such as swelling of the face, lips, tongue or throat causing difficulty in breathing
- cramps or painful, tender, or weak muscles (signs of muscle inflammation or breakdown which can cause kidney damage or even death)
- pancreatitis (Inflamed pancreas) (signs include stomach pain)
- pulmonary embolism (blood clot in the lung) (signs include chest pain and feeling breathless)
- deep vein thrombosis (a blood clot in the leg) (signs include pain, redness, or swelling in the leg)
- hepatitis (inflamed liver) (signs include yellowing of the skin and whites of the eyes (jaundice) or an increase in liver enzymes)
How To Manage Side Effects
Diarrhea
Drink lots of fluids, such as water or fruit juices, to keep yourself hydrated. Do not take any medicine on your own to manage diarrhea. Contact your doctor if the symptom does not improve.
Indigestion
Eat smaller and more frequent meals. Eat and drink slowly, and exercise regularly. Contact your doctor if the symptom does not improve.
Nausea And Vomiting
Take this medicine with or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods. Contact your doctor if the symptom does not improve.
Stomach Pain
Try to rest and relax. Take small and frequent meals. Keep a heating pad on your stomach. Contact your doctor if the symptom does not improve.
Warning & Precautions
Pregnancy
Monitoring requiredFENABRATE 145 TABLET is generally not recommended for use in pregnant women unless recommended by your doctor. Consult your doctor before taking FENABRATE 145 TABLET.
Breastfeeding
ContraindicatedFENABRATE 145 TABLET is generally not recommended for use in breastfeeding women as it may pass through breast milk. Consult your doctor before taking FENABRATE 145 TABLET.
Driving and Using Machines
Use with CautionFENABRATE 145 TABLET will not affect the ability to drive, use tools, or use machines.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking FENABRATE 145 TABLET as it causes muscle problems.
Kidney
ContraindicatedFENABRATE 145 TABLET Is not recommended for use in patients with severe kidney problems. Consult your doctor before taking FENABRATE 145 TABLET.
Liver
Consult your doctorFENABRATE 145 TABLET is not recommended for use in patients with severe liver disease and is used with caution in hepatitis and jaundice. Contact your doctor before taking FENABRATE 145 TABLET.
Allergy
ContraindicatedDo not take FENABRATE 145 TABLET if you are allergic to fenofibrate, lactose, some form of sugar, or any of the other ingredients in this medicine.
Lungs
Use with CautionFENABRATE 145 TABLET should be taken with caution in patients with lung diseases such as pulmonary embolism. Contact your doctor before taking FENABRATE 145 TABLET.
Use In Pediatrics
ContraindicatedFENABRATE 145 TABLET is generally not recommended to use in children and adolescents (under 18 years of age). Consult your doctor before taking FENABRATE 145 TABLET.
Use In Geriatrics
Use with CautionFENABRATE 145 TABLET should be used with caution in elderly patients (above 70 years of age). Consult your doctor before taking FENABRATE 145 TABLET.
Others
FENABRATE 145 TABLET is not recommended for use if you have:
- gallbladder problems
- pancreatitis
Before taking FENABRATE 145 TABLET, inform your doctor if you:
- have hypothyroidism (underactive thyroid gland)
- have diabetes
- have problems with certain proteins in the blood
- have an alcohol problem
- have a family history of muscle problems
Interactions
A. Drug-Drug interactions:
Before taking FENABRATE 145 TABLET, inform your doctor if you are taking any of the following medicine:
- medicine used to thin the blood (anti-coagulants) (Ex. warfarin)
- other medicines are used to control fat levels in the blood (Ex. statins like simvastatin, atorvastatin, pravastatin, rosuvastatin or fibrates like clofibrate, gemfibrozil)
- medicines used to manage diabetes (Ex. rosiglitazone or pioglitazone)
- medicines used to suppress the immune system (Ex. ciclosporin)
- bile acid sequestrants Ex. cholestyramine (medicines used to decrease cholesterol levels)
Overdosage:
If you or anyone else have accidentally taken too much of FENABRATE 145 TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Fenofibrate |
| Pharmacological Category | : | Fibrates |
| Therapeutic Indication | : | Hypertriglyceridemia |
| Dosage Forms | : | Tablet |
More Information
- Keep FENABRATE 145 TABLET out of reach from children
- Store at a temperature
FAQs About FENABRATE 145 TABLET
Q: Can I take FENABRATE 145 TABLET along with diabetic medication?
A: No. The medicines that are used to manage diabetes like rosiglitazone or pioglitazone, metformin and glimepiride can affect the efficacy of the FENABRATE 145 TABLET and may cause side effects. Consult your doctor before taking FENABRATE 145 TABLET.
Q: What are the common side effects of FENABRATE 145 TABLET?
A: The common side effects of FENABRATE 145 TABLET may include diarrhoea, stomach pain, wind (flatulence), feeling sick (nausea), being sick (vomiting), a rise in levels of liver enzymes in the blood and an increase in homocysteine. Contact your doctor if any of the symptoms worsens or persists.
Q: Who should not use FENABRATE 145 TABLET?
A: FENABRATE 145 TABLET is not recommended for use in patients with severe liver problems, kidney problems, gallbladder problems, pancreatitis and pregnant and breastfeeding women. Consult your doctor before taking FENABRATE 145 TABLET.
Q: Is it safe to use FENABRATE 145 TABLET by elder people?
A: FENABRATE 145 TABLET should be used with caution in elderly patients (above 70 years of age). Consult your doctor before taking FENABRATE 145 TABLET.
Q: Is FENABRATE 145 TABLET affect the driving ability?
A: FENABRATE 145 TABLET will not affect the ability to drive, use tools or use machines. Consult your doctor before taking FENABRATE 145 TABLET.
Q: Is FENABRATE 145 TABLET safe to use by pregnant women?
A: FENABRATE 145 TABLET is generally not recommended for use by pregnant women unless recommended by your doctor. Consult your doctor before taking FENABRATE 145 TABLET.
References
1. Holly E. Gurgle and Donald K. Blumenthal. Drug Therapy for Dyslipidemias. Goodman & Gilman’s The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical, 2018. Page – 605-618.
2. Konstantinos Tziomalos and Vasilios G Athyros. Uses and mechanism of Fenofibrate. International Journal of Nanomedicine. June 2006. [Accessed on 11th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426786/
3. Hua Ling, John T. Luoma, Daniel Hilleman. Introduction of Fenofibrate. Journal of Medical cases. April 2013. [Accessed on 11th June 2022] https://cardiologyres.org/index.php/Cardiologyres/article/view/270/260
4. Accord pharmaceuticals. Electronic Medicines Compendium (EMC). [Revised in April 2021] [Accessed on 11th June 2022] https://www.medicines.org.uk/emc/files/pil.5779.pdf
5. Mylan Products Ltd. Electronic Medicines Compendium (EMC). [Revised in August 2020] [Accessed on 11th June 2022] https://www.medicines.org.uk/emc/files/pil.2198.pdf
6. Ranbaxy (UK) Limited. Electronic Medicines Compendium (EMC). [Revised in April 2018] [Accessed on 11th June 2022] https://www.medicines.org.uk/emc/files/pil.4436.pdf
7. Abbott Laboratories. US Food and Drug Administration. [Revised in October 2018] [Accessed on 11th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021656s019lbl.pdf
Useful Diagnostic Tests
- Liver function test
- Kidney function test
- Lipid profile test
Author Details
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