Introduction About FADINE 40MG TABLET

FADINE 40MG TABLET contains Famotidine which belongs to the group of medicines called H2 receptor antagonists. It is used in management of stomach ulcers (gastric/duodenal ulcers), reflux esophagitis (irritation and inflammation caused by stomach acid leaking up into the oesophagus) and Zollinger-Ellison syndrome (recurrent tumours and ulcers in stomach and intestines).

Along with FADINE 40MG TABLET, your doctor might ask you to take enough rest and drink plenty of fluids. Consuming simple foods and avoiding oily and spicy foods might be beneficial as well. Before starting the management with FADINE 40MG TABLET, inform your doctor if you have a kidney disease, tumour in your stomach or are intolerant to certain sugars.

FADINE 40MG TABLET should not be used in pregnant and breast-feeding women unless considered necessary by your doctor, therefore contact your doctor. FADINE 40MG TABLET is not recommended for use in children. The most common side effects of using FADINE 40MG TABLET are headache, dizziness, constipation and diarrhoea. Inform your doctor if any of the above side effects worsen.

Uses Of FADINE 40MG TABLET

Used to manage:

• stomach ulcers (gastric or duodenal ulcers)
• reflux oesophagitis
• zollinger−ellison syndrome (recurrent ulcers and tumours in the stomach and intestines)

How FADINE 40MG TABLET Works

FADINE 40MG TABLET effectively heals stomach ulcers by blocking certain receptors called Histamine (H2) receptors which are present in the stomach walls which in turn reduces the production of gastric acid and decreases the volume of gastric secretion in the stomach.

How to use FADINE 40MG TABLET

Take FADINE 40MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of FADINE 40MG TABLET

How To Manage Side Effects

Dizziness:

When you start taking FADINE 40MG TABLET, you may feel faint or dizzy. This is caused by your blood pressure dropping. If this happens, resting or lying down for some time can help. Consult your doctor if symptoms don't improve. 

Headache:

Avoid bright lights, drink enough water and take a rest. Consult your doctor if symptoms don't improve. 

Constipation:

Eat plenty of fiber-rich foods such as fresh fruits, vegetables and cereals and drink plenty of water. Exercise more regularly. Consult your doctor if symptoms don't improve. 

Diarrhea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Consult your doctor if symptoms don't improve.

Warning & Precautions

Pregnancy

FADINE 40MG TABLET is not recommended for use in pregnant women or women planning to have a baby unless your doctor thinks the benefits outweigh the risks. Consult your doctor before taking it.

Breastfeeding

FADINE 40MG TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.

Driving and Using Machines

Do not drive or operate any machines if you feel dizzy or have a headache after taking FADINE 40MG TABLET.

Kidney

FADINE 40MG TABLET should be taken with caution in patients with kidney disease. The dose will be adjusted by your doctor. Consult your doctor before taking it.

Allergy

Do not take FADINE 40MG TABLET if you are allergic to Famotidine or any other ingredients of this medicine.

Interactions

A. Drug – Drug Interactions:

• medicines used to manage fungal infections (Ex. ketoconazole, itraconazole)
• medicines used to manage gout (Ex. probenecid)
• antacids like aluminium hydroxide, calcium carbonate (medicines used to manage indigestion)
• medicines used to manage the recurrence of ulcers (Ex. sucralfate)
• medicines used for high blood phosphate levels in patients on dialysis (Ex. calcium carbonate)
• medicines used for management of HIV infection (Ex. atazanavir)

Overdosage:

If you or anyone else accidentally takes too much of FADINE 40MG TABLET, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep FADINE 40MG TABLET out of reach of children
• Store at room temperature not above 25°C

FAQs About FADINE 40MG TABLET

Can I take FADINE 40MG TABLET along with antifungal medicines like ketoconazole?

No, since FADINE 40MG TABLET reduces the amount of acid in your stomach, antifungal medicines will not work well as it is best absorbed in an acidic environment. Consult your doctor before taking it.

Can FADINE 40MG TABLET be used in pregnancy?

FADINE 40MG TABLET is not recommended for use in pregnant women or women planning to have a baby unless your doctor thinks the benefits outweigh the risks. Consult your doctor before taking it.

What precautions do I have to take while taking FADINE 40MG TABLET?

Patients taking FADINE 40MG TABLET should inform the doctor if they have any kidney disease or tumor in the stomach. FADINE 40MG TABLETis not recommended for use in pregnant and breastfeeding women. Consult your doctor before taking it.

What does FADINE 40MG TABLET do?

FADINE 40MG TABLET effectively heals stomach ulcers by blocking certain receptors called Histamine (H2) receptors which are present in the stomach walls which in turn reduces the production of gastric acid and decreases the volume of gastric secretion in the stomach.

Will FADINE 40MG TABLET manage stomach pain?

No, FADINE 40MG TABLET do not manage normal stomach pain. It is intended to manage stomach ulcers, reflux esophagitis and Zollinger-Ellison syndrome. By managing all these they provide relief to the patients but do not directly deal with stomach pain.

References

1. KD. Tripathi. Gastrointestinal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 650.

2. P A Abraham, J A Opsahl, C E Halstenson, A N Chremos, G R Matzke, W F Keane. The effect of famotidine on renal function in patients with renal insufficiency. NIH. National Library of Medicine, National centre for biotechnology information. Pubmed.gov. Sept 1987. [Accessed on 30th April 2022] https://pubmed.ncbi.nlm.nih.gov/2889461/#:~:text=These%20data%20suggest%20that%20famotidine,renal%20elimination%20of%20basic%20drugs.

3. Kim Nguyen, Graham D. Dersnah , Rajni Ahlawat. Famotidine. NIH. National Library of Medicine, National center for biotechnology information. Pubmed.gov. 2022. [Accessed on 30th April 2022] https://pubmed.ncbi.nlm.nih.gov/30521199/

4. Kleva Pharmaceuticals S.A. Electronic Medicines Compendium (EMC). [Revised in Jan 2022] [Accessed on 30th April 2022] https://www.medicines.org.uk/emc/files/pil.11524.pdf

Useful Diagnostic Tests

• Ultrasound
• Complete Blood Count (CBC)
• Gastrointestinal Endoscopy