Introduction About EXTHRO 250 TABLET

EXTHRO 250 TABLET contains Erythromycin, which belongs to the group of medicines called Macrolide antibiotics. It is used in the management of various bacterial infections such as throat and sinus infections, chest infections (such as bronchitis and pneumonia), eye and ear infections, mouth and dental infections, skin and tissue infections (such as acne), and stomach and intestinal infections.

Also, it is used to manage infections following burns, operations, or dental procedures and manages other infections such as sexually transmitted diseases, bone infections, or scarlet fever.

Inform your doctor before taking any blood tests, as EXTHRO 250 TABLET may interfere with the laboratory investigation. Do not stop taking EXTHRO 250 TABLET until your course is over without consulting your doctor.

EXTHRO 250 TABLET is not recommended for use in patients with heart rhythm disorders or with a family history of heart rhythm disorders, an abnormality of the electrocardiogram, or low levels of potassium or magnesium in the blood.

EXTHRO 250 TABLET should be used with caution in patients with liver or heart disease, myasthenia gravis (muscle weakness), who have or ever had diarrhea following the use of antibiotics.

EXTHRO 250 TABLET should be used with caution in pregnant women and with sexually transmitted disease syphilis. It should be used with caution in breast-feeding women. EXTHRO 250 TABLET should be used with caution in children above 8 years of age and in children who feel irritable or vomit after being managed with antibiotics.

The common side effects of taking EXTHRO 250 TABLET are nausea, vomiting, stomach pain, diarrhea, and loss of appetite. Consult your doctor if any of the side effects worsen.

Uses Of EXTHRO 250 TABLET

Manages bacterial infections such as:

• Throat and sinus infections
• Chest infections (such as bronchitis and pneumonia)
• Ear infections
• Mouth and dental infections
• Eye infections
• Skin and tissue infections (such as acne)
• Stomach and intestinal infections
• Infection following burns, operations, or dental procedures
• Other infections (such as sexually transmitted diseases, bone infections, or scarlet fever) 

How EXTHRO 250 TABLET Works

EXTHRO 250 TABLET contains erythromycin, a bacteriostatic in action that manages the further growth of bacteria rather than directly killing the bacteria. Erythromycin works by blocking protein synthesis in the bacteria. It does not affect protein synthesis in human tissues. When administered orally, it is easily absorbed from the gastrointestinal system. Thus, EXTHRO 250 TABLET manages bacterial infections.

How to use EXTHRO 250 TABLET

Take EXTHRO 250 TABLET as advised by your physician. Swallow EXTHRO 250 TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

Side Effects Of EXTHRO 250 TABLET

How To Manage Side Effects

Diarrhea

Drink a lot of fluids, such as water or fruit juices, to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhea. Consult your doctor if the diarrhea does not improve.

Nausea And Vomiting

Try to take EXTHRO 250 TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating oil-rich, fried, or spicy foods. Consult your doctor if the nausea and vomiting do not improve.

Stomach Pain

Rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heat pad on your stomach. Do not self-manage on your own and consult your doctor if the stomach pain does not improve. 

Warning & Precautions

Pregnancy

Monitoring required

EXTHRO 250 TABLET should be used during pregnancy only if considered clearly necessary. Consult your doctor before taking EXTHRO 250 TABLET.

Breastfeeding

Use with Caution

EXTHRO 250 TABLET should be used with caution in breast-feeding women. Consult your doctor before taking EXTHRO 250 TABLET.

Driving and Using Machines

Safe

EXTHRO 250 TABLET does not influence your abilities to drive or operate any machines. 

Alcohol

Contraindicated

Consumption of alcohol is not recommended during management with EXTHRO 250 TABLET.

Liver

Use with Caution

EXTHRO 250 TABLET should be used with caution in patients with liver problems. Consult your doctor before taking EXTHRO 250 TABLET.

Allergy

Contraindicated

Do not take EXTHRO 250 TABLET if you are allergic to erythromycin, clarithromycin, or azithromycin.

Heart Disease

Consult your doctor

EXTHRO 250 TABLET is not recommended for use in patients with heart rhythm disorders or with a family history of heart rhythm disorders or an abnormality of the electrocardiogram. It should be used with caution in patients with heart problems. Consult your doctor before taking EXTHRO 250 TABLET.

Use In Pediatrics

Consult your doctor

EXTHRO 250 TABLET is not recommended for use in children under 8 years of age, and it should be used with caution in children and adolescence above 8 years of age and in children who feel irritable or vomit after being managed with antibiotics. Consult your child’s doctor for advice.

Interactions

A. Drug-Drug interactions:

Before taking EXTHRO 250 TABLET, inform your doctor if you are taking any of the following medicines:

• Medicine used to manage migraines (Ex. ergotamine or dihydroergotamine)

• Medicines used to manage allergic reactions (Ex. astemizole, terfenadine, mizolastine)
• Medicine used to manage nausea and vomiting (Ex. domperidone)
• Medicines used to manage GERD (Ex. cisapride, cimetidine, and omeprazole)
• Pimozide, amisulpride (used to manage psychiatric conditions)
• Simvastatin (used to manage high cholesterol)
• Tolterodine (used in the management of overactive bladder)
• Colchicine (used in the management of gout and arthritis)
• Medicines used in the management of bacterial infection (Ex. clarithromycin, rifabutin, or rifampicin)
• Medicines used to manage fungal infections (Ex. fluconazole, ketoconazole, and itraconazole)
• Medicines used to manage heart problems (Ex. digoxin, disopyramide, or quinidine)
• Medicine used to manage peripheral circulation problems (Ex. cilostazol)
• Medicines used to produce sleep (Ex. hexobarbitone, phenobarbitone, zopiclone, midazolam)
• Medicine used to manage blood clots (Ex. warfarin, acenocoumarol, and rivaroxaban)
• Medicines used to manage epilepsy (Ex. valproate, carbamazepine, or phenytoin)
• Medicine used to manage asthma and breathing problems (Ex. theophylline)
• Medicines used to manage organ rejection (Ex. ciclosporin or tacrolimus)
• Bromocriptine (used to manage Parkinson’s disease)
• Triazolam, alprazolam (used to manage anxiety)
• Alfentanil (used to relive pain)
• Methylprednisolone (used to manage inflammation)
• St. John’s wort (used to manage mental illness)
• Medicine used to manage high blood pressure (Ex. verapamil)
• Vinblastine (used to manage cancer)
• Medicine used to manage erectile dysfunction (Ex. sildenafil)
• Medicines used to manage viral infections (Ex. saquinavir)
• Medicines used to manage pregnancy (Ex. ethinyl estradiol)

Overdosage:

If you or anyone else accidentally take too much of EXTHRO 250 TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of EXTHRO 250 TABLET include temporary hearing loss, nausea, vomiting, and diarrhea.

Synopsis

More Information

FAQs About EXTHRO 250 TABLET

Q: What is EXTHRO 250 TABLET used for?

A: EXTHRO 250 TABLET is used in the management of various bacterial infections such as throat and sinus infections, chest infections (such as bronchitis and pneumonia), eye and ear infections, mouth and dental infections, skin and tissue infections (such as acne), and stomach and intestinal infections. Also, it is used to manage infections following burns, operations, or dental procedures and manages other infections such as sexually transmitted diseases, bone infections, or scarlet fever. 

Q: Is EXTHRO 250 TABLET safe to use in patients with heart problems?

A: EXTHRO 250 TABLET is not recommended for use in patients with heart rhythm disorders or with family history of heart rhythm disorders or an abnormality of the electrocardiogram. It should be used with caution in patients with heart problems. Consult your doctor before taking it. 

Q: Can EXTHRO 250 TABLET be used in pregnant and breast-feeding women?

A: EXTHRO 250 TABLET should be used during pregnancy only if clearly advised by the doctor, and it should be used with caution in breast-feeding women. Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breast-feeding your child. 

Q: How does EXTHRO 250 TABLET work?

A: EXTHRO 250 TABLET contains erythromycin, a bacteriostatic in action that manages the further growth of bacteria rather than directly killing the bacteria. Erythromycin works by blocking protein synthesis in the bacteria. It does not affect protein synthesis in human tissues. When administered orally, it is easily absorbed from the gastrointestinal system. Thus, EXTHRO 250 TABLET manages bacterial infections.

Q: Does EXTHRO 250 TABLET cause diarrhea?

A: Yes, EXTHRO 250 TABLET may cause diarrhea in some individuals. To manage this effect, drink a lot of fluids, such as water or fruit juices, to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhea. Consult your doctor if the symptom does not improve.

Q: Can EXTHRO 250 TABLET be used in children?

A: EXTHRO 250 TABLET is not recommended for use in children under 8 years of age, and it should be used with caution in children and adolescence above 8 years of age and in children who feel irritable or vomit after being managed with antibiotics. Consult your child’s doctor for advice.

Q: What are the side effects of taking EXTHRO 250 TABLET?

A: The common side effects of taking EXTHRO 250 TABLET are nausea, vomiting, stomach pain, diarrhea, and loss of appetite. Consult your doctor if any of the side effects worsen.

Q: How does EXTHRO 250 TABLET work?

A: EXTHRO 250 TABLET contains erythromycin, a bacteriostatic in action that manages the further growth of bacteria rather than directly killing the bacteria. Erythromycin works by blocking protein synthesis in the bacteria. It does not affect protein synthesis in human tissues. When administered orally, it is easily absorbed from the gastrointestinal system. Thus, EXTHRO 250 TABLET manages bacterial infections.

Q: Who should not take EXTHRO 250 TABLET?

A: EXTHRO 250 TABLET is not recommended for use in patients with heart rhythm disorders or with family history of heart rhythm disorders or an abnormality of the electrocardiogram, have low levels of potassium (hypokalaemia), low levels of magnesium (hypomagnesaemia), or are allergic to erythromycin, clarithromycin, or azithromycin. Consult your doctor before taking it.

Q: What precautions must be taken while using EXTHRO 250 TABLET?

A: Before taking EXTHRO 250 TABLET, inform your doctor if you have heart problems, liver problems, myasthenia gravis (muscle weakness), or a history of diarrhea following the use of antibiotics.

References

1. K.D. Tripathi. Macrolide, Lincosamide, Glycopeptide, and Other Antibacterial Antibiotics Urinary Antiseptics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page no – 752.

2. Farzam K, Nessel TA, Quick J. Erythromycin. NIH National Library of Medicine, National Center for Biotechnology Information. June 2022. [Accessed on 29th July 2024] https://www.ncbi.nlm.nih.gov/books/NBK532249/

3. Aesica Queenborough Limited. Electronic Medicines Compendium (EMC). [Revised in June 2022] [Accessed on 29th July 2024] https://www.medicines.org.uk/emc/files/pil.404.pdf

4. Abbott Laboratories, U.S. Food & Drug Administration [Revised in November 2010] [Accessed on 29th July 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/050611s027lbl.pdf

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Peripheral Smear Examination By Pathologist
• Healthy Midlife Checkup
• Men Health Checkup – Advanced
• Complete Women Checkup
• Senior Citizen Checkup - Female
• Senior Citizen Checkup - Male
• Full Body Checkup - Gold
• Full Body Checkup – Silver