Introduction About EXCLUV 625 TABLET

EXCLUV 625 TABLET is used to manage bacterial infections, including middle ear and sinus infections, respiratory tract infections, genital tract infections, urinary tract infections, skin and soft tissue infections such as dental infections, bone and joint infections, septic abortion, and abdominal infections. The symptoms of bacterial infection include fever, difficulty breathing, pus formation, and pain.

It contains a combination of medicines called Amoxicillin and Clavulanic acid, which belong to the group of medicines called Antibiotics. It works by preventing the growth of bacteria and helps clear up the infection.

EXCLUV 625 TABLET is not recommended for use if you have liver problems or jaundice upon taking an antibiotic or amoxicillin-clavulanate. Before taking this medicine, inform your doctor if you are suffering from a hepatic impairment, liver disease, renal impairment, kidney disease, glandular fever, or are unable to pass water properly.

EXCLUV 625 TABLET should be used with caution in pregnant and breastfeeding women only if it is considered necessary. It should be used with caution in children (aged below 12 years) and elderly patients (above 50 years).

The common side effects associated with the use of EXCLUV 625 TABLET are diarrhea, thrush (fungal infection in the vagina, skin folds, or mouth), nausea, and vomiting. Contact your doctor immediately if any of the symptoms worsen.

Uses Of EXCLUV 625 TABLET

• Manage bacterial infection

How EXCLUV 625 TABLET Works

EXCLUV 625 TABLET helps in managing bacterial infection where amoxicillin is a penicillin that works by inhibiting the enzymes that help in the synthesis of the integral structural component of the bacterial cell wall whereas clavulanic acid is a beta-lactam (structurally related to penicillin) that works by inactivating an enzyme, namely beta-lactamase, thereby managing the inactivation of amoxicillin.

How to use EXCLUV 625 TABLET

• Take this medicine as advised by your physician.
• For Tablet, Capsule: Swallow the tablet with a glass of water. Do not crush or chew the medicine.
• For Dispersible Tablet: Disperse EXCLUV 625 TABLET in the specified quantity of water as mentioned in the label.
• Consume the mixture immediately after reconstitution.
• Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

Side Effects Of EXCLUV 625 TABLET

Common Side Effects of EXCLUV 625 TABLET:

• Diarrhoea
• thrush (fungal infection in the vagina, skin folds, or mouth)
• nausea
• vomiting

Stop taking EXCLUV 625 TABLET and contact your doctor if you experience any of the following side effects:

• inflammation of the liver (hepatitis), jaundice

Warning & Precautions

Pregnancy

Monitoring required

EXCLUV 625 TABLET should be used with caution in pregnant women only if it is considered clearly necessary.

Breastfeeding

Use with Caution

EXCLUV 625 TABLET should be used with caution in breastfeeding women.

Driving and Using Machines

Contraindicated

Do not drive or operate machines while taking if you feel unwell.

Kidney

Use with Caution

EXCLUV 625 TABLET should be used with caution in patients with renal impairment or kidney problems.

Liver

Consult your doctor

EXCLUV 625 TABLET is not recommended for use if you have ever had liver problems or jaundice upon taking an antibiotic or amoxicillin-clavulanate. It should be used with caution in patients with hepatic impairment or liver problems.

Allergy

Contraindicated

Do not take EXCLUV 625 TABLET if you are allergic to amoxicillin, clavulanic acid, penicillin, any antibiotic, or any other ingredients of this medicine.

Use In Pediatrics

Use with Caution

EXCLUV 625 TABLET should be used with caution in children (below 12 years).

Use In Geriatrics

Use with Caution

EXCLUV 625 TABLET should be used with caution in elderly patients (above 50 years).

Interactions

A. Drug-Drug Interactions

Before taking EXCLUV 625 TABLET, inform your doctor if you are taking any of the following medicines:

• allopurinol, probenecid (medicine used to manage gout)
• warfarin (medicine used to inhibit blood clotting)
• methotrexate (medicine used to manage rheumatic diseases or certain cancers)
• mycophenolate mofetil (a medicine used to manage the organ rejection after organ transplant)
• contraceptives (medicines used to manage conception)

Overdosage:

If you or anyone else accidentally takes too much of EXCLUV 625 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are gastrointestinal symptoms (including heartburn, indigestion, bloating, and constipation).

Synopsis

FAQs About EXCLUV 625 TABLET

References

1. KD Tripathi. Beta-Lactam Antibiotics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 723.

2. Justin Evans, Maryam Hannoodee, and Micah Wittler. Amoxicillin Clavulanate. NIH National Library of Medicine. National Centre for Biotechnology Information. Stat Pearls [Internet]. December 2021. [Assessed on 7th October 2024] click here

3. Lek Pharmaceuticals d.d., Health Products Regulatory Authority (HPRA). [Revised in December 2014] [Assessed on 7th October 2024] click here

4. GSK group of companies. Augmentin. [Revised in December 2017] [Assessed on 7th October 2024] click here

5. Macleods Pharmaceuticals Ltd. Polyclav DS Tab. [Assessed on 7th October 2024] click here

6. Amoxicillin and Clavulanic acid. Micro Labs Ltd. [Assessed on 7th October 2024] click here

User Feedback

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Kidney Function Test (KFT)
• Liver Function Test (LFT)
• Serum Electrolytes/ Electrolytes Profile
• Urine Routine & Microscopy
• Full Body Checkup – Gold
• Full Body Checkup – Silver

Author Details

Written By Srilekha. R - B.Pharm

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 21 Nov 2024 | 03:11 PM(IST)