ETOBRIX 90 Capsule 10's
Introduction About ETOBRIX 90 CAPSULE
ETOBRIX 90 CAPSULE is used to reduce pain and swelling associated with inflammatory bone conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (inflammation of the spine), and gout (joint pain caused by excessive accumulation of uric acid in between the joints). It can also be used to reduce pain following a dental surgery. It contains Etoricoxib, which belongs to the group of medicines called Non-Steroidal Anti-Inflammatory Drugs. It works by blocking the release of certain chemicals (prostaglandins) in the body that cause pain, swelling, and inflammation, thereby reducing pain and inflammation associated with inflammatory conditions.
Before taking ETOBRIX 90 CAPSULE, inform your doctor if you have any history of heart, liver, or kidney problems. You must also inform your doctor if you have diabetes, high blood cholesterol levels, uncontrollable high blood pressure, or severe dehydration. ETOBRIX 90 CAPSULE is strictly not recommended for use in patients with stomach problems (such as stomach ulcers, bleeding in the gut, or inflammatory bowel diseases). It is also not suitable for use in patients with stroke or any severe form of heart problems, liver problems, or kidney problems.
It is suitable for use in adults and adolescents (aged 16 years or older). Do not take ETOBRIX 90 CAPSULE if you are pregnant or breastfeeding without consulting your doctor. The most common side effects of taking ETOBRIX 90 CAPSULE are stomach pain, bloating, constipation, mouth ulcers. Consult your doctor immediately if any of these side effects worsen.
Uses Of ETOBRIX 90 CAPSULE
It is used in adults and in adolescents (aged 16 years or older) to:
- Manage pain and swelling caused by inflammation of bones and joints
- Manage pain following dental surgery
How ETOBRIX 90 CAPSULE Works
ETOBRIX 90 CAPSULE is a pain-relieving medicine. It works by blocking the release of certain chemicals (prostaglandins) in the body that cause pain, swelling, and inflammation, thereby reducing pain and inflammation associated with inflammatory conditions.
How to use ETOBRIX 90 CAPSULE
- Take ETOBRIX 90 CAPSULE as advised by your physician
- Swallow the medicine with a glass of water. Do not crush or chew the medicine
- ETOBRIX 90 CAPSULE can be taken with or without food
- Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and disease condition
Side Effects Of ETOBRIX 90 CAPSULE
Common side effects of ETOBRIX 90 CAPSULE:
- stomach pain
- constipation, flatulence, heartburn, indigestion, diarrhea
- mouth ulcer
- feeling weak or tired
- infections of the respiratory or urinary tract
- tingling and numbness in the body
- changes in bowel habits, dry mouth, stomach ulcers
Stop taking ETOBRIX 90 CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- chest pain, shortness of breath, swollen ankles
- severe stomach pain with dark stools
- jaundice (yellow colouration of the skin and the eyes)
- signs of an allergic reaction (such as skin rash, itching, blistering, and peeling of the skin, swelling of the face, lips, mouth, and throat, which may lead to breathing difficulties)
Warning & Precautions

Pregnancy
ContraindicatedETOBRIX 90 CAPSULE should not be used during pregnancy. Therefore, inform your doctor before taking the medicine if you are pregnant, think you may be pregnant, or are planning to have a baby.

Breastfeeding
Consult your doctorIt is not known whether ETOBRIX 90 CAPSULE can pass through breast milk or not. Therefore, consult your doctor before taking the medicine if you are breastfeeding or planning to breastfeed.

Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if you feel dizzy or sleepy after taking the medicine.

Alcohol
Consult your doctorAvoid consumption of alcohol while taking ETOBRIX 90 CAPSULE, as it may increase the risk of stomach discomfort.

Kidney
ContraindicatedETOBRIX 90 CAPSULE is not recommended for use in patients with serious kidney diseases.

Liver
ContraindicatedETOBRIX 90 CAPSULE is not recommended for use in patients with serious liver diseases.

Allergy
ContraindicatedDo not take ETOBRIX 90 CAPSULE if you are allergic to Etoricoxib or any ingredients of this medicine.

Heart Disease
ContraindicatedETOBRIX 90 CAPSULE is not recommended for use in patients who have or had heart failure, angina, heart attack, bypass surgery, blocked blood vessels, or poor blood circulation in the body.

Use In Pediatrics
Monitoring requiredETOBRIX 90 CAPSULE should be used in adolescents aged 16 years or above only if prescribed by the physician. It should not be used in children and adolescents (aged below 16 years).

Use In Geriatrics
Use with CautionETOBRIX 90 CAPSULE should be used with caution in elderly patients (aged above 65 years).
Others
ETOBRIX 90 CAPSULE is not recommended for use if you:
- currently have ulcers or bleeding in stomach or intestines
- have inflammatory bowel diseases (crohn’s disease or ulcerative colitis)
- have uncontrollably high blood pressure
- had stroke (including mini-stroke, transient ischemic attack)
Before taking ETOBRIX 90 CAPSULE, inform your doctor if you
- have a previous history of stomach ulcers
- are dehydrated due to prolonged vomiting or diarrhea
- have a history of high blood pressure
- have edema (swelling of body parts)
- are being managed for an infection
- have diabetes
- have high cholesterol
- are a smoker
Interactions
A. Drug-Drug interactions:
Before taking ETOBRIX 90 CAPSULE, inform your doctor if you are taking any of the following medicines, such as:
- Anticoagulant (Ex. Warfarin)
- Antibiotics (Ex. Rifampicin)
- Antimetabolites (Ex. Methotrexate)
- Immunosuppressants (Ex. Cyclosporin, Tacrolimus)
- Anti-maniac agents (Ex. Lithium)
- ACE inhibitors (Ex. enalapril, ramipril)
- Angiotensin receptor blockers (Ex. losartan, valsartan)
- Diuretics (Ex. bumetanide, ethacrynic acid)
- Cardiac glycosides (Ex. Digoxin)
- Vasodilators (Ex. Minoxidil)
- Bronchodilators (Ex. Salbutamol)
- Antiprogestational steroids (Ex. mifepristone, drospirenone, ethinylestradiol)
- Hormone replacement therapy (Ex. estradiol, dydrogesterone)
- Nonsteroidal anti-inflammatory drug (NSAID) (Ex. Aspirin)
Overdosage:
If you or anyone else accidentally took more of ETOBRIX 90 CAPSULE, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Etoricoxib | 
| Pharmacological Category | : | Selective COX-2 Inhibitor | 
| Therapeutic Indication | : | Pain relief | 
| Dosage Forms | : | Tablet, Capsule, Injection | 
FAQs About ETOBRIX 90 CAPSULE
Q: Is ETOBRIX 90 CAPSULE safe to use in diabetic patients?
A: It may alter the blood sugar levels in the body. Therefore, it is necessary to inform your doctor if you have diabetes before taking the medicine as a precaution.
Q: Is ETOBRIX 90 CAPSULE an anti-inflammatory medicine?
A: Yes. It is an anti-inflammatory medicine used to reduce pain and inflammation. It acts by blocking the release of certain chemicals (Ex. prostaglandins) in the body that cause pain and inflammation.
Q: Who should not take ETOBRIX 90 CAPSULE?
A: Generally, patients who have stomach problems like stomach ulcers or other inflammatory stomach conditions such as ulcerative colitis, Crohn’s disease, or perforations or bleeding in the gut should not take the medicine. Consult your doctor before taking this medicine if you are pregnant or trying to become pregnant. ETOBRIX 90 CAPSULE is also not suitable for use in patients with stroke or severe liver, kidney, or heart disease and in children aged below 16 years.
Q: Is ETOBRIX 90 CAPSULE safe to use for the long term?
A: Research shows that prolonged use of ETOBRIX 90 CAPSULE can increase the risk of heart attack or stroke in some patients. Your doctor will regularly monitor health condition while taking the medicine to avoid these side effects.
Q: Can I take other painkillers along with ETOBRIX 90 CAPSULE?
A: No, it is not advisable to take other painkillers along with ETOBRIX 90 CAPSULE without consulting your doctor, as it may increase the risk of ulcers and bleedings in the digestive system.
Q: Is it safe to have ETOBRIX 90 CAPSULE with alcohol?
A: No. Avoid consumption of alcohol while taking ETOBRIX 90 CAPSULE, as it increases the risk of unwanted gastrointestinal side effects.
Q: Can ETOBRIX 90 CAPSULE cause dizziness?
A: Yes. ETOBRIX 90 CAPSULE may make you feel dizzy. If you experience dizziness, try to rest and relax. Get enough sleep. Avoid driving or operating any heavy tools or machines while you are feeling dizzy. Avoid consumption of alcohol, as it can aggravate your dizziness. Consult your doctor if you continue to feel dizzy for a prolonged period.
Q: Can I take a higher dose of ETOBRIX 90 CAPSULE?
A: It is not safe to take a higher dose of ETOBRIX 90 CAPSULE without consulting your doctor. If the prescribed dose is less effective for you, kindly consult your doctor for a suitable high dose or for alternative therapy.
Q: How long will it take for ETOBRIX 90 CAPSULE to reduce pain?
A: It may take around 20-30 minutes for ETOBRIX 90 CAPSULE to start working. The maximum benefits can be achieved after 2 hours of taking ETOBRIX 90 CAPSULE. However, this period may vary from person to person depending upon the dose of etoricoxib that is administered.
Q: What happens if I accidentally take more ETOBRIX 90 CAPSULE?
A: If you or anyone else accidentally take more ETOBRIX 90 CAPSULE, contact your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include severe stomach problems such as stomach pain, bleeding in the gut, and a fast heartbeat.
Q: Can I take ETOBRIX 90 CAPSULE daily?
A: Your doctor will evaluate the health condition and suggest whether you can take ETOBRIX 90 CAPSULE every day or not.
Q: Can I stop taking ETOBRIX 90 CAPSULE once my pain reduces?
A: Take ETOBRIX 90 CAPSULE for the stipulated duration recommended by your doctor to achieve maximum results. Do not stop therapy with ETOBRIX 90 CAPSULE without consulting your doctor in between the therapy.
Q: What are the uses of ETOBRIX 90 CAPSULE?
A: ETOBRIX 90 CAPSULE is used to reduce pain and swelling associated with inflammatory bone conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout. It can also be used to reduce pain following dental surgery.
Q: Can ETOBRIX 90 CAPSULE be used in children?
A: Yes. ETOBRIX 90 CAPSULE should be used in adolescents aged 16 years or above only if prescribed by the physician.
Q: How does ETOBRIX 90 CAPSULE work?
A: ETOBRIX 90 CAPSULE is a pain-relieving medicine. It works by blocking the release of certain chemicals (prostaglandins) in the body that cause pain, swelling, and inflammation, thereby reducing pain and inflammation associated with inflammatory conditions.
Q: What are the side effects of ETOBRIX 90 CAPSULE?
A: The most common side effects of taking ETOBRIX 90 CAPSULE are stomach pain, bloating, constipation, mouth ulcers, headache, and dizziness. Consult your doctor immediately if any of these side effects worsen.
Q: What is the best time to take ETOBRIX 90 CAPSULE?
A: ETOBRIX 90 CAPSULE can be taken with or without meals. Your doctor will decide the best time for you to take ETOBRIX 90 CAPSULE based on your age, body weight, and disease condition.
Q: What to do if I forgot to take a dose of ETOBRIX 90 CAPSULE?
A: If you forgot to take a dose of ETOBRIX 90 CAPSULE, take it as soon as you remember. However, if it is time for the next dose of ETOBRIX 90 CAPSULE, skip the missed dose and take the next one regularly. Do not take a double dose of ETOBRIX 90 CAPSULE to compensate for the missed ones.
Q: Will ETOBRIX 90 CAPSULE alter the effects of birth control pills?
A: ETOBRIX 90 CAPSULE may reduce the effects of birth control pills. Therefore, try to avoid taking birth control pills along with this medicine.
References
1. KD. Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 206.
2. Wen-Nan Huang and Tim K. Tso. Etoricoxib improves osteoarthritis pain relief, joint function, and quality of life in the extreme elderly. NIH National Library of Medicine, National Center for Biotechnology Information. PMC PubMed Central. [Revised in February 2018] [Accessed on 30th July 2024] click here
3. Merck Sharp & Dohme B.V. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 30th July 2024] click here
4. Teva UK Limited. Etoricoxib. [Revised in August 2022] [Accessed on 30th July 2024] click here
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