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Quality Checked ProductsIntroduction About ENAL H 10MG TABLET
ENAL H 10MG TABLET is a combination of Enalapril and Hydrochlorothiazide which belongs to the group of medicines called Antihypertensive agents. It is used in the management of hypertension (high blood pressure). It is typically used in patients who have not responded adequately to therapy with either of the single agents.
Before taking ENAL H 10MG TABLET inform your doctor if you have any lung, liver, kidney or heart problems. You must also inform your doctor if you have diabetes, low blood pressure or severe dehydration as a precaution.
ENAL H 10MG TABLET is not recommended for use in patients with severe hypotension or severe kidney problems. It is also not suitable for use in women who are pregnant or breastfeeding due to increased risk of side effects.
During management with ENAL H 10MG TABLET your doctor will constantly monitor your kidney functions, blood pressure, electrolyte levels and blood sugar levels to avoid the risk of unwanted side effects.
The most common side effects of taking ENAL H 10MG TABLET are headache, dizziness, tiredness, low blood pressure, muscle cramps, low blood sugar levels and increased blood cholesterol and potassium levels. Consult your doctor if any of these side effects trouble you.
Uses Of ENAL H 10MG TABLET
- Manage hypertension (high blood pressure)
How ENAL H 10MG TABLET Works
ENAL H 10MG TABLET is an antihypertensive medicine. It relaxes your blood vessels and improves blood flow across them. It also reduces thickness of the blood by removing excess fluids from the body in the form of urine. Collectively, these actions reduce the strain on the heart and helps the heart to pump blood more smoothly with less pressure.
How to use ENAL H 10MG TABLET
Take ENAL H 10MG TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. ENAL H 10MG TABLET can be taken with or without food.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Continue to take ENAL H 10MG TABLET for the stipulated duration instructed by your doctor to achieve better results.
Side Effects Of ENAL H 10MG TABLET
Common
- headache, dizziness
- nausea, stomach pain, diarrhea
- blurred vision
- weakness, tiredness
- low blood pressure, feeling faint
- depression
- heart rhythm changes (fast or slow)
- skin rash
- high or low blood potassium levels
- increased blood cholesterol levels
- increased blood uric acid levels
- muscle cramps
Uncommon
- signs of low blood sugar (anxiety, shakiness)
- signs of low sodium levels (loss of energy, restlessness, confusion, muscle weakness)
- anemia (low RBC in blood)
- difficulty in sleeping
- vertigo (spinning sensation)
- numbness, tingling or prickling sensation in arms, legs or feet
- runny nose, sore throat, hoarse voice
- vomiting, loss of appetite, indigestion, constipation
- dry mouth, excessive sweating
- hair loss
- joint pain
- low blood magnesium levels
Rare
- abnormal dreams
- signs of pneumonia (cough, high temperature and difficulty breathing)
- nose inflammation
- pain, inflammation or ulceration of the gums, cheeks, tongue, lips and throat
- enlargement of breast in men (gynecomastia)
- swollen glands in neck, armpit or groin
- fingers and toes become numb and cold (Raynaud’s phenomenon)
Stop taking ENAL H 10MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- eye pain, decrease in vision
- skin lesions
- severe allergic reactions like angioedema (such as rash, swelling of the face, lips, mouth, throat or airways which can lead to difficulty in breathing or swallowing)
- chest pain or tightness
- severe dizziness or feeling faint while standing up suddenly
- inflammation of pancreas (causing severe stomach pain that radiates to the back side of the body)
- signs of block in the gut (such as severe stomach pain, constipation with stomach discomfort or bloating, nausea and vomiting)
- signs of kidney problems (such as passing no urine or little urine, bloody urine, changes in urine color, lowe back pain, nausea, vomiting, tiredness)
- signs of low blood count (such as tiredness, pale skin, increased infections, breathing difficulties, fever, chills, sore throat, mouth ulcers, unusual bleeding or bruising)
- severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane)
- signs of liver problems (such as fever, muscle pain, rashes, itching, stomach pain, diarrhea, discoloration of eyes, skin and urine)
How To Manage Side Effects
Nausea and vomiting:
Take ENAL H 10MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Constipation:
Eat plenty of fibre rich foods such as fresh fruits, vegetables and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.
Warning & Precautions
Pregnancy
ENAL H 10MG TABLET is not recommended for use in pregnant women as it may cause serious harm to the growing fetus. Therefore, inform your doctor before taking this medicine if you are pregnant, think you may be pregnant or planning to have a baby. If you accidentally become pregnant while undergoing therapy with ENAL H 10MG TABLET, inform your doctor immediately.
Breastfeeding
ENAL H 10MG TABLET is not recommended for use in breast-feeding women. Therefore, consult your doctor before taking it.
Driving and Using Machines
Do not drive or operate any heavy tools or machines if you feel dizzy after taking ENAL H 10MG TABLET.
Alcohol
Avoid consumption of alcohol while taking ENAL H 10MG TABLET as it may severely decrease your blood pressure and make you feel dizzier or faint.
Kidney
ENAL H 10MG TABLET is not recommended for use in patients with severe kidney impairment (including dialysis). It should be used with caution in patients with other kidney problems (including kidney transplantation or renal artery stenosis). Therefore, consult your doctor before taking it.
Liver
ENAL H 10MG TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it.
Allergy
Do not take ENAL H 10MG TABLET if you are allergic to Hydrochlorothiazide, Enalapril or to any other ACE inhibitor (such as captopril lisinopril, ramipril).
Lungs
ENAL H 10MG TABLET should be used with caution in patients with asthma. It should also be used with caution among patients who previously developed any breathing problems following the consumption of this medicine. Therefore, consult your doctor before taking it.
Heart Disease
ENAL H 10MG TABLET should be used with caution in patients with heart problems (such as ischemic heart disease (low oxygen supply to heart muscles), heart block, narrowing of heart valves, heart failure etc.). Therefore, consult your doctor before taking it.
Others
ENAL H 10MG TABLET is not recommended for you, if you:
- have a family history of allergic reactions (such as angioedema)
- are not passing urine
- have diabetes with impaired kidney functions
- have severe low blood pressure (hypotension)
Before taking ENAL H 10MG TABLET, inform your doctor if you:
- have any blood disorders
- have low blood pressure
- are on a salt-restricted diet
- are severely dehydrated due to any recent sickness such as vomiting or diarrhea
- have problems in the blood vessels supplying the brain
- have any autoimmune disease that affects the skin or collagen (Ex. lupus erythematosus, rheumatoid arthritis or scleroderma)
- have gout (joint pain caused due to accumulation of uric acid)
- have diabetes
- have hyperkalaemia (high blood potassium levels)
- have fluids/electrolyte imbalance in the body
- are going to check your parathyroid gland
- have previously had skin cancer
- are scheduled for any upcoming surgery
- are scheduled for LDL apheresis (a procedure to remove cholesterol from the blood)
- have any desensitization management (used to reduce the effect of an allergy to bee or wasp stings)
Use in Paediatrics:
ENAL H 10MG TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before consumption.
Use in Geriatrics:
ENAL H 10MG TABLET should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
Interactions
A. Drug-Drug interactions:
Before taking ENAL H 10MG TABLET inform to your doctor, if you are taking any of the following medicines such as:
- medicines used for heart conditions such as hypertension, chest pain, irregular heartbeats or heart failure (Ex. atenolol, propranolol, nitroglycerin, valsartan, candesartan, irbesartan, methyldopa, aliskiren, amiodarone, sotalol, quinidine, hydroquinidine, disopyramide, dofetilide, ibutilide, procainamide, digitalis, sacubitril/valsartan)
- medicines used to manage organ transplant rejection (Ex. ciclosporin, temsirolimus, sirolimus, everolimus)
- racecadotril (a medicine used to manage diarrhea)
- anti-diabetic medicines and insulin (used to lower the blood glucose level) Ex. vildagliptin, metformin
- medicines that supplement potassium to the body (Ex. spironolactone, triamterene or amiloride)
- lithium (a medicine used in some types of mental illness)
- thrombolytics (used to dissolve blood clots) Ex. reteplase, tenecteplase
- other diuretics (used to reduce edema) Ex. furosemide, bumetanide
- trimethoprim containing antibiotics (used for infections)
- heparin (used to manage blood clots)
- medicines used to induce sleep (Ex. alprazolam, midazolam)
- tricyclic antidepressants (used to manage depression) Ex. amitriptyline
- antipsychotics (used to manage serious mental illnesses) Ex. clozapine, risperidone
- anesthetics (used to manage pain during surgery) Ex. propofol, thiopental
- medicines used to relieve pain (Ex. morphine, aspirin, diclofenac, diflunisal, celecoxib, valdecoxib)
- medicines used to control blood cholesterol levels (such as cholestyramine or colestipol)
- gold therapy (used to manage rheumatic conditions)
- medicines used to suppress cough (such as dextromethorphan, guaiphenesin, pseudoephedrine)
- adrenaline or nor-adrenaline (used for low blood pressure, shock, cardiac failure, asthma or allergies)
- corticotropin (used to check the function of adrenal gland)
- corticosteroids (used to manage inflammation) Ex. prednisolone
- medicines used to manage gout (such as probenecid, sulfinpyrazone and allopurinol)
- cyclophosphamide or methotrexate (medicine used to manage cancer)
- carbenoxolone (a medicine used to manage stomach ulcers)
- laxatives (used to manage constipation) Ex. lactulose
- tubocurarine, dantrolene (medicines used as a muscle relaxant)
- calcium supplements and/or vitamin D supplements
- carbamazepine (a medicine used to manage epilepsy)
- amphotericin B (a medicine used to manage fungal infections)
- iodinated contrast agents (used during X-ray procedures)
- atropine (a medicine used to improve heart rate)
- biperiden (a medicine used to manage parkinsonism)
Overdosage:
If you or anyone else accidentally took more ENAL H 10MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include low blood pressure, fast or slow heartbeat, palpitations, shock, fast breathing, cough, nausea, vomiting, dizziness, feeling sleepy and confused or anxious, excessive urination or not being able to urinate.
Synopsis
| Drug | : | Enalapril, Hydrochlorothiazide |
| Pharmacological Category | : | Angiotensin-II converting enzyme inhibitor, Thiazide like diuretic |
| Therapeutic Indication | : | Hypertension |
| Dosage Forms | : | Tablet |
More Information
- Keep ENAL H 10MG TABLET out of reach to children
- Store ENAL H 10MG TABLET at normal room temperature
FAQs About ENAL H 10MG TABLET
What are the uses of ENAL H 10MG TABLET?
ENAL H 10MG TABLET is used to manage hypertension.
What type of a medicine is ENAL H 10MG TABLET?
ENAL H 10MG TABLET is an antihypertensive medicine. It relaxes your blood vessels and improves blood flow across them. It also reduces thickness of the blood by removing excess fluids from the body in the form of urine. Collectively, these actions reduce the strain on the heart and helps the heart to pump blood more smoothly with less pressure.
What happens when I stop taking ENAL H 10MG TABLET?
Do not stop taking ENAL H 10MG TABLET without consulting your doctor as your blood pressure may raise once again. Make sure to take ENAL H 10MG TABLET for the stipulated duration recommended by your doctor to achieve maximum results.
What is the best time to take ENAL H 10MG TABLET?
ENAL H 10MG TABLET can be taken with or without meals. Your doctor will decide the best time for you to take ENAL H 10MG TABLET based on your age, body weight and disease condition.
What to do if I forgot to take a dose of ENAL H 10MG TABLET?
If you forgot to take a dose of ENAL H 10MG TABLET, take it as soon as you remember. However, if it is time for the next dose of ENAL H 10MG TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of ENAL H 10MG TABLET to compensate the missed ones.
What precautions should be followed while taking ENAL H 10MG TABLET?
Before taking ENAL H 10MG TABLET, inform your doctor if you have any heart, liver or kidney problems. You must also inform your doctor if you have diabetes, low blood pressure volume or are severely dehydrated. Stop taking ENAL H 10MG TABLET and consult your doctor immediately if you become pregnant. Regularly visit your doctor and take all the necessary blood test recommended by your doctor without fail.
Can I consume alcohol while taking ENAL H 10MG TABLET?
Avoid consumption of alcohol while taking ENAL H 10MG TABLET as it might make you feel dizzier and drowsier.
What happens if I accidentally take more ENAL H 10MG TABLET?
If you or anyone else accidentally took more ENAL H 10MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include low blood pressure, fast or slow heartbeat, palpitations, shock, fast breathing, cough, nausea, vomiting, dizziness, feeling sleepy and confused or anxious, excessive urination or not being able to urinate.
Can I take ENAL H 10MG TABLET daily?
Take ENAL H 10MG TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take ENAL H 10MG TABLET every day or not.
Is ENAL H 10MG TABLET safe to use in diabetic patients?
ENAL H 10MG TABLET may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before taking ENAL H 10MG TABLET as a precaution. Your doctor will closely monitor you blood sugar levels to avoid the risk of side effects.
What are the side effects of ENAL H 10MG TABLET?
The most common side effects of taking ENAL H 10MG TABLET are headache, dizziness, tiredness, low blood pressure, muscle cramps, low blood sugar levels and increased blood cholesterol and potassium levels. Consult your doctor if any of these side effects trouble you.
Can I stop taking ENAL H 10MG TABLET once my symptoms subside?
No. Do not stop taking ENAL H 10MG TABLET without consulting your doctor. As hypertension is a chronic condition, long term management may be necessary to control its symptoms. Therefore, take ENAL H 10MG TABLET as advised by your doctor for the stipulated duration. Premature discontinuation of therapy may increase your blood pressure once again.
Can ENAL H 10MG TABLET be taken during pregnancy?
ENAL H 10MG TABLET is not recommended for use in pregnant women as it may cause serious harm to the growing fetus. Therefore, inform your doctor before taking ENAL H 10MG TABLET if you are pregnant, think you may be pregnant or planning to have a baby. If you become pregnant while undergoing therapy with ENAL H 10MG TABLET, stop taking it and consult your doctor immediately.
Is ENAL H 10MG TABLET safe to use in kidney disease?
ENAL H 10MG TABLET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems (such as kidney transplant, narrowing of renal arteries). Your doctor will access your health condition and suggest a suitable dose for you. Therefore, it is important to inform your doctor if you have any kidney problems before taking ENAL H 10MG TABLET as a precaution.
Can the use of ENAL H 10MG TABLET affect the liver?
Yes. ENAL H 10MG TABLET may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it is strictly not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other minor liver problems. Consult your doctor before taking it.
Can ENAL H 10MG TABLET cause photosensitivity reactions?
Yes. ENAL H 10MG TABLET may cause patients to become more sensitive to sunlight or ultraviolet radiation. Therefore, avoid going out or minimize the exposure of natural sunlight or artificial UV rays. In case of while going out protect your skin by applying a suitable sunscreen recommended by your doctor. You must also inform your doctor if you have any previous history of skin problems (such as skin cancer) before taking ENAL H 10MG TABLET as a precaution.
References
1. KD Tripathi. Drugs affecting Renin-angiotensin system. Antihypertensive drugs. Diuretics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 502, 559, 572 & 582.
2. Shirley J.Middlemost MD., Robin Tager MD., Jean Davis RNP., Sareli MD. Effectiveness of enalapril in combination with low-dose Hydrochlorothiazide versus enalapril alone for mild to moderate systemic hypertension in black patients. The American Journal of Cardiology. ScienceDirect.com. June 1994. [Accessed on 12th December 2022]. https://www.sciencedirect.com/science/article/abs/pii/0002914994902895
3. Gerard Laboratories. Electronic Medicines Compendium (EMC). [Revised in April 2022]. [Accessed on 12th December 2022]. https://www.medicines.org.uk/emc/files/pil.9862.pdf
4. Dexcel Pharma. Electronic Medicines Compendium (EMC). [Revised in October 2021]. [Accessed on 12th December 2022]. https://www.medicines.org.uk/emc/files/pil.2671.pdf
5. Taro Pharmaceuticals U.S.A., Inc. Enalapril Maleate and Hydrochlorothiazide Tablet. Dailymed.com. [Revised in October 2020]. [Accessed on 12th December 2022]. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7cb92cf2-46f2-4379-937c-168d230e43a4
6. Vaseretic. American Society of Health-System Pharmacists. Inc. Medline Plus. National Library of Medicine. [Revised in May 2019]. [Accessed on 12th December 2022]. https://medlineplus.gov/druginfo/meds/a601047.html#:~:text=The%20combination%20of%20enalapril%20and,so%20blood%20flows%20more%20smoothly
Useful Diagnostic Tests
- Kidney Function Test
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