INTRODUCTION

ECOFLOX OR contains Ofloxacin which belongs to a group of medicines called quinolone antibiotics. It is used to manage conditions such as respiratory tract, urinary tract, gynaecological and skin soft tissue infections. Ofloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Ofloxacin is in a class of antibiotics called fluoroquinolones which works against bacteria that cause infections and stops the growth of the bacteria causing the infection and clears the infection. 

Before taking ECOFLOX OR inform your doctor if you have any allergic reactions, liver, kidney or heart problems. Inform your physician if you are pregnant or breastfeeding. It is not suitable for children and adolescents below 18 years of age.  The common side effects are nausea, stomach pain, diarrhoea or headache.

USES OF ECOFLOX OR

• Manages respiratory tract, urinary tract, gynaecological and skin soft tissue infections (bacterial infections)

HOW ECOFLOX OR WORKS

ECOFLOX OR works against bacteria that cause infections and stops the growth of the bacterial enzyme called DNA-gyrase thus prevents the bacterial cells from dividing and repairing them.

DIRECTIONS FOR USE

Always take ECOFLOX OR as instructed by your doctor. Swallow as whole and do not crush or chew. Do not exceed the recommended dose. 

SIDE EFFECTS OF ECOFLOX OR

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink plenty of fluids and ORS can be used to prevent dehydration.

Nausea:

Drink clear or ice-cold drinks, eat bland foods and avoid fried or sweet foods.

Stomach pain:

Place a warm water bottle on your abdomen. Soak in a warm bath. Drink plenty of clear fluids and water.

Headache:

Rest and drink plenty of fluids. Apply a wet or cold cloth to forehead and rest in a quiet, comfortable, dark room.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking,

• ciprofloxacin, nadifloxacin, norfloxacin (manages infection)
• quinidine, hydroquinidine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide (manages heart problems)
• clomipramine, amitriptyline (used to manage depression)
• erythromycin, clarithromycin, azithromycin
• medicines or dietary supplements that contain iron (for anaemia) or zinc
• sucralfate (used for stomach ulcers)
• antacids, cimetidine
• corticosteroids, used for management of inflammation and swelling
• ibuprofen or diclofenac and theophylline
• glibenclamide (manages diabetes)
• probenecid (used for gout)
• methotrexate (used for rheumatism)
• warfarin (manages blood clot)
• didanosine (used to manage HIV infections)
• furosemide

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT ECOFLOX OR

Can I stop taking ECOFLOX OR when my symptoms are relieved?

No, do not stop taking and complete the full course of management even if you feel better.

Can the use of ECOFLOX OR cause diarrhea?

Yes. It may cause diarrhea, if you are experiencing severe diarrhea, consult your doctor for advice.

How long does ECOFLOX OR take to work?

Usually, it starts working soon after taking and it may take some days to act against the harmful bacteria.

REFERENCES

1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015.Page. 1011-13.

2. Mylan, Potters Bar. Gerard Laboratories. Electronic Medicines Compendium (EMC); [Revised on Sep, 2020] [Accessed on August 26, 2021] https://www.medicines.org.uk/emc/files/pil.8480.pdf

3. Teva Pharmaceutical Works Ltd. Pharmachemie B.V. May, 2021. [Accessed on August 26, 2021] https://mri.cts-mrp.eu/human/downloads/NL_H_4742_001_FinalPL.pdf

4. Medlineplus. [Revised on July 15, 2019] [Accessed on August 26, 2021] https://medlineplus.gov/druginfo/meds/a691005.html

USEFUL DIAGNOSTIC TESTS

• Complete Blood Count
• Peripheral Smear Examination