It contains Duloxetine which is an antidepressant medicine which controls depression by altering the levels of certain brain chemicals that causes depression and urinary incontinence.

Uses Of DUPATHY 30 TABLET

DUPATHY 30 TABLET is used to manage:

• major depressive disorders
• diabetic neuropathic pain
• generalized anxiety disorder
• stress urinary incontinence in women

How DUPATHY 30 TABLET Works

DUPATHY 30 TABLET works by increasing the amount of serotonin and norepinephrine (natural substances in the brain that help maintain mental balance and stop the movement of pain signals), resulting in relief of anxiety, pain and depression. DUPATHY 30 TABLET helps in managing stress urinary incontinence by increasing the strength of the muscle responsible for holding back urine when you laugh, sneeze or perform physical activities.

How to use DUPATHY 30 TABLET

• Take DUPATHY 30 TABLET as advised by your physician.
• Swallow it with water. Do not crush or chew the medicine.
• You may find it easier to take DUPATHY 30 TABLET at the same times daily to help you remember to take it.
• Your doctor will decide the right dose and duration of depending upon your age, body weight and severity of the disease.
• Do not stop taking DUPATHY 30 TABLET unless your doctor advises you to stop.

Side Effects Of DUPATHY 30 TABLET

Common Side Effects of DUPATHY 30 TABLET:

• nausea, dry mouth, constipation, loss of appetite, gas
• diarrhea, heartburn, indigestion, stomach pain, vomiting
• trouble sleeping, agitation, decreased sex drive, anxiety, difficulty or failure to gain orgasm, unusual dreams
• headache, dizziness, feeling sluggish, sleepiness, shaking, numbness, pricking or tingling of the skin
• blurred eyesight, spinning sensation
• increased blood pressure, flushing, throbbing sensation
• increased sweating, weakness, shivering
• ringing in ears
• increased yawning, extreme tiredness
• itchy rash
• muscle pain or spasm
• painful or frequent urination
• trouble getting an erection, changes in ejaculation
• falls
• weight loss

Stop taking DUPATHY 30 TABLET and contact your doctor immediately if you experience any of the following side effects:

• sensing restlessness or unable to sit or stand still
• thoughts of harming or killing self

Warning & Precautions

Pregnancy

Consult your doctor

DUPATHY 30 TABLET should be used in pregnant women only after discussing the potential benefits and risks to your unborn child with your doctor.

Breastfeeding

Contraindicated

DUPATHY 30 TABLET is not recommended for use in breastfeeding mothers.

Driving and Using Machines

Use with Caution

Do not drive or use machineries if you feel dizzy or sleepy after taking DUPATHY 30 TABLET.

Alcohol

Use with Caution

Alcohol should be consumed with caution while taking DUPATHY 30 TABLET.

Kidney

Consult your doctor

DUPATHY 30 TABLET is not recommended for use in patients with severe kidney disease. DUPATHY 30 TABLET should be used with caution in other kidney diseases.

Liver

Contraindicated

DUPATHY 30 TABLET is not recommended for use in patients with liver disease.

Allergy

Contraindicated

Do not take DUPATHY 30 TABLET if you are allergic to Duloxetine or any of the other ingredients of this medicine.

Heart Disease

Use with Caution

DUPATHY 30 TABLET should be used with caution in patients with high blood pressure or other heart diseases.

Use In Pediatrics

Contraindicated

DUPATHY 30 TABLET is generally not recommended for use in children (below 18 years of age). 

Use In Geriatrics

Use with Caution

DUPATHY 30 TABLET should be used with caution in elderly patients as they are more prone to certain side effects. 

Interactions

A. Drug - Drug interactions:

Before taking DUPATHY 30 TABLET, inform your doctor if you are taking any of the following medicines:

• medicines used as antidepressants (Ex. moclobemide, paroxetine, fluoxetine, venlafaxine, clomipramine, amitriptyline, pethidine, St John’s Wort)
• linezolid (used to manage bacterial infections)
• Anxiolytics (Ex. alprazolam, clonazepam)
• Pain killers (Ex. tramadol, buprenorphine)
• Antipsychotic agents (Ex. olanzapine, quetiapine, phenobarbital)
• medicines used to manage allergic conditions (Ex. loratadine, cetirizine)
• medicines used to manage migraine (Ex. sumatriptan, naratriptan)
• tryptophan (used for protein synthesis in the body)
• medicines used to manage blood clots (Ex. warfarin, rivaroxaban)

Overdosage:

If you or anyone else accidentally take too much of DUPATHY 30 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of DUPATHY 30 TABLET overdosage are sleepiness, serotonin syndrome (a rare reaction causing feelings of great happiness, drowsiness, clumsiness, restlessness, feeling drunk, fever, sweating, rigid muscles), fits, vomiting and fast heartrate.

Synopsis

More Information

For more information on Duloxetine:

FAQs About DUPATHY 30 TABLET

Q: What if I miss a dose of DUPATHY 30 TABLET?

A: If you forget a dose of DUPATHY 30 TABLET, take it as soon as you remember. However, if it is time for your next dose, skip the forgotten one and take only a single dose as usual. Leave out the missed dose if it's almost time for the next one. Do not take more than the daily amount of DUPATHY 30 TABLET that has been prescribed for you in a day.

Q: Can I stop taking DUPATHY 30 TABLET on my own?

A: No. Do not stop taking DUPATHY 30 TABLET without your doctor’s advice even if you feel better. Your doctor may gradually reduce the dose before stopping management altogether. If you stop taking DUPATHY 30 TABLET suddenly, you may have symptoms such as dizziness, tingling feelings or electric shock-like feelings, sleep disturbances, extreme tiredness, sleepiness, restlessness, agitation, anxiety, nausea, vomiting, shaking, headaches, muscle pain, irritability, diarrhoea, excessive sweating or spinning sensation.

Q: How soon can I see the effects of DUPATHY 30 TABLET?

A: DUPATHY 30 TABLET starts to work in most people with depression or anxiety within two weeks of starting management, but it may take 2-4 weeks before you feel better. Your doctor may continue to give you DUPATHY 30 TABLET when you are feeling better to manage your depression or anxiety from returning. In people with diabetic neuropathic pain, it can take a few weeks before you feel better.

Q: Can DUPATHY 30 TABLET be given to children?

A: No. DUPATHY 30 TABLET is used for adults and generally not recommended for children and adolescents below 18 years of age. Your doctor may prescribe DUPATHY 30 TABLET for patients under 18 if decided that this is in their best interests. If your doctor has prescribed DUPATHY 30 TABLET for your child and you want to discuss this, please go back to your doctor. Inform your doctor if you see your child experiencing any symptoms like suicide attempt or ideas, aggression, oppositional behaviour and anger.

Q: Can DUPATHY 30 TABLET make me have suicidal thoughts?

A: During initial management with DUPATHY 30 TABLET, you might have suicidal thoughts. In such case, call your doctor or go to a hospital straight away. You may find it helpful to confront a relative or close friend and ask them to tell you if they think your depression or anxiety is worsening or if they are concerned about changes in your behaviour.

Q: Can I take DUPATHY 30 TABLET on an empty stomach?

A: Take DUPATHY 30 TABLET as advised by your doctor. You can take DUPATHY 30 TABLET with or without food. Try taking DUPATHY 30 TABLET at same time each day which will help you in remembering your dose.

References

1. KD Tripathi. Drugs Used in Mental Illness. Essentials of Medical Pharmacology. Eighth Edition. 2019. Page – 490.

2. David J Goldstein. Duloxetine in the treatment of major depressive disorder. NIH National Library of Medicine. National center for biotechnology information. Pubmed.gov. April 2007. [Accessed on 6th June 2024] click here

3. Trevor R Norman, James S Olver. Duloxetine in the treatment of generalized anxiety disorder. NIH National Library of Medicine. National center for biotechnology information. Pubmed Central. December 2009. [Accessed on 6th June 2024] click here

4. Wolfgang Jost, Parvaneh Marsalek. Duloxetine: mechanism of action at the lower urinary tract and Onuf's nucleus. NIH National Library of Medicine. National center for biotechnology information. Pubmed.gov. August 2004. [Accessed on 6th June 2024] click here

5. Dr. Reddy’s Laboratories (UK) Ltd. Electronic Medicines Compendium (EMC). [Revised in April 2024] [Accessed on 6th June 2022] click here

6. Pharmadox Healthcare Ltd. Electronic Medicines Compendium (EMC). [Revised in May 2021] [Accessed on 6th June 2024] click here

7. Icon Lifesciences. Dulotin (Duloxetin 10mg). [Accessed on 6th June 2024] click here

Useful Diagnostic Tests

• Frequent Pain Check Package
• Healthians Special Full Body Checkup – Male
• Healthians Diamond Senior Male Package
• Healthians Special Full Body Checkup – Female
• Culture And Sensitivity, Urine

Author Details

Written By Srilekha. R - B.Pharm

Reviewed By Dr. Sankara Babu Gorle - MBBS, MD(Pharmacology) View profile

Last updated on 18 Nov 2024 | 03:34 PM(IST)