Introduction About DOMI BABY ORAL DROPS

DOMI BABY ORAL DROPS contains Domperidone which belongs to the group of medicines called Dopamine antagonists. It is used to manage nausea (feeling sick) and vomiting (being sick).

Nausea and vomiting are not a disease but symptoms of different conditions such as infections, food poisoning, motion sickness, overeating, blocked intestine, migraine, indigestion and many more.

DOMI BABY ORAL DROPS is not recommended for use in patients having heart or moderate to severe liver diseases, bleeding in the stomach or intestines, blockage or tear in your intestines, and tumors in the pituitary gland (prolactinoma). DOMI BABY ORAL DROPS should be used with caution in patients having kidney diseases.

DOMI BABY ORAL DROPS should be used with caution in pregnant women and should be used in breastfeeding women only if considered clearly necessary by the doctor. Ask for your doctor’s advice before taking. DOMI BABY ORAL DROPS should be used with caution in elderly patients (above 60 years of age).

DOMI BABY ORAL DROPS should not be used in children below 12 years or weighing less than 35kgs. Consult with your child’s doctor. The common side effect of taking DOMI BABY ORAL DROPS includes dry mouth. Consult with your doctor if this worsens or doesn’t improve.

Uses Of DOMI BABY ORAL DROPS

• manages nausea and vomiting

How DOMI BABY ORAL DROPS Works

DOMI BABY ORAL DROPS has an anti-emetic property which acts by blocking a chemical messenger in the brain called dopamine, that transfers information through nerve endings. DOMI BABY ORAL DROPS functions by inhibiting the muscle contraction that occurs naturally in the digestive system and enhances the peristaltic movement in the food pipe which helps in facilitating the digestion time faster, this causes calming down effect, thereby relieving nausea or vomiting sensation.

How to use DOMI BABY ORAL DROPS

Take DOMI BABY ORAL DROPS as advised by your physician. Shake well before use. Your doctor will decide the appropriate dose and duration of DOMI BABY ORAL DROPS for you depending on your age, body weight and disease condition.

Side Effects Of DOMI BABY ORAL DROPS

How To Manage Side Effects

Dry mouth:

Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your physician for advice.

Diarrhoea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Ask for your doctor’s advice if diarrhoea doesn’t improve.

Headache:

Try to take rest and don’t involve yourself in exertive activities. Rest in a quiet and dark room. Apply a pain-relieving balm on your forehead. Ask for your doctor’s advice if the headache doesn’t improve

Drowsiness:

Take adequate sleep. Do not involve in rigorous activities. Do not interfere with your sleep cycle. Talk to your doctor if the drowsiness doesn’t improve.

Itchy skin:

Hot water makes your skin irritated, so avoid taking hot showers. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. To soothe and hydrate the irritated skin, apply moisturizers. Contact your doctor if itching worsens.

Warning & Precautions

Pregnancy

DOMI BABY ORAL DROPS should be used with caution in pregnant women. Consult your doctor before taking it.

Breastfeeding

DOMI BABY ORAL DROPS is not recommended for use in breastfeeding women as it may pass through breast milk. DOMI BABY ORAL DROPS may cause unwanted side effects affecting the heart in a breastfed baby. It should only be used only if considered clearly necessary by the doctor. Consult your doctor before taking DOMI BABY ORAL DROPS.

Driving and Using Machines

DOMI BABY ORAL DROPS does not affect the ability to drive or use machines.

Kidney

DOMI BABY ORAL DROPS should be taken with caution in patients with kidney problems such as kidney impairment or kidney failure. Your doctor might consider adjusting your dose. Consult your doctor before taking it.

Liver

DOMI BABY ORAL DROPS is not recommended for use in patients having moderate to severe liver diseases such as liver function impairment or liver failure. Consult your doctor before taking it.

Allergy

Do not take DOMI BABY ORAL DROPS if you are allergic to Domperidone or any other ingredients present in it.

Heart Disease

DOMI BABY ORAL DROPS is not recommended in patients suffering from heart problems such as prolonged QT corrected interval (reading in eco cardiogram (ECG) machine) or heart failure (heart cannot pump blood properly). Kindly consult a doctor before taking DOMI BABY ORAL DROPS.

Interactions

A. Drug-Drug interactions:

Before taking DOMI BABY ORAL DROPS, inform your doctor if you are taking any of the following medicines:

• medicines to manage fungal infections (Ex. ketoconazole, fluconazole, and voriconazole)
• medicines to manage bacterial infections (Ex. erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine)
• medicine to manage heart problems or high blood pressure (Ex. amiodarone, dronedarone, quinidine, disopyramide, bepridil, dofetilide, sotalol, diltiazem, verapamil)
• medicines to manage psychoses (Ex. haloperidol, pimozide, sertindole), medicine to manage depression (Ex. citalopram, escitalopram)
• medicines to manage gastrointestinal disorders (such as cisapride, diphemanil, dolasetron, prucalopride)
• medicines to manage allergies (Ex. mequitazine, mizolastine)
• medicine to manage malaria (specifically halofantrine)
• medicines to manage AIDS/HIV (Ex. ritonavir, atazanavir)
• medicine to manage cancer (Ex. toremifene, vandetanib, vincamine)
• medicine used to manage drug addiction (Ex. methadone)

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. The symptoms might include feeling sleepy, confused, uncontrolled movements of the eye and tongue and abnormal posture (like a twisted neck).

Synopsis

More Information

• Keep DOMI BABY ORAL DROPS out of reach of children
• Store DOMI BABY ORAL DROPS at room temperature below 30°C

FAQs About DOMI BABY ORAL DROPS

What is DOMI BABY ORAL DROPS and why is it prescribed?

DOMI BABY ORAL DROPS contains Domperidone which belongs to the group of medicines called Dopamine antagonists. It is used in managing nausea and vomiting.

How long can I take DOMI BABY ORAL DROPS?

It is recommended that DOMI BABY ORAL DROPS be taken for the shortest period and at the lowest dose. This is because DOMI BABY ORAL DROPS can cause an irregular heartbeat when taken for a longer period or at a high dose. Ask for your doctor’s advice.

Can I take DOMI BABY ORAL DROPS with antibiotics?

Use of DOMI BABY ORAL DROPS with antibiotics like erythromycin, levofloxacin, and some antifungals is not recommended as this can cause interaction. Please consult your doctor for advice before using any antibiotics with DOMI BABY ORAL DROPS.

Does DOMI BABY ORAL DROPS increase milk secretion?

Yes, DOMI BABY ORAL DROPS can increase milk secretion also known as galactorrhoea. This is an uncommon side effect of using DOMI BABY ORAL DROPS. Talk to your doctor if you are experiencing this side effect while taking this medicine.

Does DOMI BABY ORAL DROPS cause heart problems?

DOMI BABY ORAL DROPS may be associated with an increased risk of heart problems (like an irregular heartbeat) and heart attacks. The risk also increases when DOMI BABY ORAL DROPS is given together with other medicines.  Inform the doctor of your medication history when taking DOMI BABY ORAL DROPS.

Does DOMI BABY ORAL DROPS cause dry mouth?

Yes, DOMI BABY ORAL DROPS can cause dry mouth. Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your physician for advice.

What is the best time to take DOMI BABY ORAL DROPS?

It is recommended to take DOMI BABY ORAL DROPS before meals. If taken after meals, absorption of the medicine is somewhat delayed. Patients should try to take each dose of DOMI BABY ORAL DROPS at a scheduled time to avoid missing a dose.

References

1. KD Tripathi. Antiemetics. Essentials of Medical Pharmacology. Eighth edition. 2019. Page - 414.

2. Rhew K, Han N, Oh JM. Impact of Safety Warning on Domperidone Prescribing for Geriatric Patients in South Korea: Analysis of National Insurance Claim Data. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed Central. August 2019. [Accessed on 3rd November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719182/

3. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubchem. Domperidone. [Accessed on 3rd November 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Domperidone

4. Savio C Reddymasu, Irfan Soykan, Richard W McCallum. Domperidone: review of pharmacology and clinical applications in gastroenterology. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed.gov. September 2007. [Accessed on 3rd November 2022] https://pubmed.ncbi.nlm.nih.gov/17488253/

5. Sofarimex - Industria Quimica e Farmacêutica Lda. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed on 03rd November 2022] https://www.medicines.org.uk/emc/files/pil.3188.pdf                                                          

6. Torrent Pharmaceuticals Ltd. Domstal Baby (Domperidone). [Revised in February 2022] [Accessed on 3rd November 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2518.pdf

7. Medley Pharmaceuticals Ltd. Motinorm drops (Domperidone). [Accessed on 3rd November 2022] https://www.medleylab.com/product/suprakare/anti-emetic.html

8. Torque Pharmaceuticals Pvt. Ltd. Peridon Drops (Domperidone). [Accessed on 3rd November 2022] https://www.torquepharma.com/peridon-drops/

9. Aristo Pharma Ltd. Apuldon (Domperidone). [Accessed on 3rd November 2022]. https://aristopharma.com/upload/product_pdf/1649581141.pdf