Introduction About DEXOZEST 2MG TABLET

DEXOZEST 2MG TABLET contains Dexchlorpheniramine which belongs to the group of medicines called Antihistamines. It is used to manage perennial, seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, mild uncomplicated allergic skin manifestations of urticaria and angioedema (swelling underneath skin).

Allergic rhinitis is a diagnosis associated with a group of symptoms affecting the nose caused by irritation and inflammation of the nasal membrane. These symptoms occur when you breathe in something you are allergic to, such as dust, pollen or animal dander. Symptoms are sneezing, itchiness and a blocked or runny nose.

DEXOZEST 2MG TABLET may provide relief from itching caused by skin conditions such as allergic eczema, pruritus ani, pruritus vulvae, atopic dermatitis, contact dermatitis, insect bites, dermographism and medication reactions (serum sickness).

Before taking this medicine DEXOZEST 2MG TABLET inform your doctor if you have liver, kidney or heart disease, glaucoma (increased pressure in the eye), enlargement of prostrate, hyperthyroidism or seizures.

DEXOZEST 2MG TABLET should be used in pregnant women only if clearly needed and should not be taken during last 3 months of pregnancy. It should be used with caution in breastfeeding women as it passes through breast milk. Consult with your doctor before taking DEXOZEST 2MG TABLET.

DEXOZEST 2MG TABLET is not recommended for use in children below 2 years of age. It should be used with caution in elderly patients above 60 years of age. Ask for your doctor’s advice before taking DEXOZEST 2MG TABLET.

The common side effects of taking DEXOZEST 2MG TABLET are drowsiness, headache, blurred vision and dry mouth. Consult with your doctor if any of these worsen or doesn’t improve.

Uses Of DEXOZEST 2MG TABLET

Manage:

• perennial, seasonal allergic rhinitis
• vasomotor rhinitis
• allergic conjunctivitis
• mild uncomplicated allergic skin manifestations of urticaria and angioedema

How DEXOZEST 2MG TABLET Works

DEXOZEST 2MG TABLET acts by inhibiting the effects of histamine, a naturally occurring chemical in the body which is responsible for causing the allergic symptoms.

How to use DEXOZEST 2MG TABLET

Always take this DEXOZEST 2MG TABLET as prescribed by the doctor. Swallow the medicine as a whole, do not crush or chew. Your doctor will prescribe the right dose and frequency depending on your age, body weight and severity of infection.

Side Effects Of DEXOZEST 2MG TABLET

How To Manage Side Effects

Nausea:

Take this medicine with or after meals. Stick to simple meals while taking this medicine. Avoid eating rich or spicy food. Do not take any medication on your own. Ask for your doctor’s advice if nausea doesn’t improve.

Headache:

Try to take rest and don’t involve yourself in exertive activities. Rest in a quiet and dark room. Apply a pain-relieving balm on your forehead. Ask for your doctor’s advice if headache doesn’t improve

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, oily or sweet foods. Avoid carbonated drinks. Ask for your doctor’s advice if vomiting doesn’t improve.

Dizziness:

Lie or sit down immediately when you feel dizzy. If you're feeling severe episode of spinning(vertigo), lie in a dark and quite place with eyes closed. Try to avoid vehicle driving. Discuss with your doctor if the symptom worsens.

Dry mouth:

Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your physician for advice.

Warning & Precautions

Pregnancy

DEXOZEST 2MG TABLET should be used in pregnant women only if clearly needed and should not be taken during last 3 months of pregnancy. Consult your doctor for advice.

Breastfeeding

DEXOZEST 2MG TABLET it should be used with caution during breastfeeding as it passes through the breast milk. Consult your doctor for advice.

Driving and Using Machines

Do not drive or handle any machines if you experience drowsiness after taking DEXOZEST 2MG TABLET.

Alcohol

Do not consume alcohol while taking DEXOZEST 2MG TABLET as it may cause drowsiness.

Kidney

DEXOZEST 2MG TABLET should be used with caution in patients with kidney disease. Consult your doctor for advice.

Liver

DEXOZEST 2MG TABLET should be used with caution in patients with liver disease. Consult your doctor for advice.

Allergy

Tell your doctor if you are allergic (hypersensitive) to Dexchlorpheniramine or any other ingredients of this medicine.

Heart Disease

DEXOZEST 2MG TABLET should be used with caution in patients with heart problems. Consult your doctor for advice.

Interactions

A. Drug - Drug interactions:

Before taking DEXOZEST 2MG TABLET, inform your physician if you are taking any of the following medicines:

• zolpidem, triazolam, midazolam, phenobarbital (used to induce sleep)
• opioid analgesics such as tramadol, fentanyl (used to manage severe pain)
• amitriptyline, imipramine, isocarboxazid (used to manage depression)
• oral anticoagulants such as heparin (used to manage blood clot)

Overdosage:

If you or anyone else accidentally take too much of DEXOZEST 2MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage include central nervous system depression, apnoea, arrhythmias, cardiovascular problem, cyanosis, diminished mental alertness, sedation, convulsions, hallucinations, insomnia, tremors, ataxia, blurred vision, dizziness, hypotension and tinnitus. Symptoms of overdose in children are dry mouth, fixed dilated pupils, flushing, gastrointestinal symptoms and hyperthermia.

Synopsis

More Information

• Keep DEXOZEST 2MG TABLET out of reach of children
• Store DEXOZEST 2MG TABLET at a temperature below 25°C

FAQs About DEXOZEST 2MG TABLET

What is DEXOZEST 2MG TABLET and why is it prescribed?

DEXOZEST 2MG TABLET contains Dexchlorpheniramine which belongs to the group of medicines called Antihistamines. It is used to manage perennial, seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, mild uncomplicated allergic skin manifestations of urticaria and angioedema (swelling underneath skin).

Can DEXOZEST 2MG TABLET make me feel drowsy?

DEXOZEST 2MG TABLET may cause dizziness or drowsiness in some individuals. Do not drive or handle any machines if you experience drowsiness after taking DEXOZEST 2MG TABLET.

Is it safe to use DEXOZEST 2MG TABLET in pregnant women?

DEXOZEST 2MG TABLET should be used during the first two trimesters of pregnancy only if clearly needed. DEXOZEST 2MG TABLET is not recommended for use in the third trimester of pregnancy because newborn and premature infants may have severe reactions to antihistamines.

Should DEXOZEST 2MG TABLET be taken with food?

Take DEXOZEST 2MG TABLET as advised by your doctor. It can be taken before or after food. Try to take your dose of DEXOZEST 2MG TABLET at same time each day as it will make it easier for you to remember taking your medicine.

Can DEXOZEST 2MG TABLET be given to children?

DEXOZEST 2MG TABLET is not recommended to use in children under 2 years of age due to the risk of respiratory depression. Caution should be exercised when administering DEXOZEST 2MG TABLET to paediatric patients 2 years of age and older. Consult with your child’s doctor before giving DEXOZEST 2MG TABLET to your child.

References

1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Schwinghammer, Cecily V. DiPiro. Allergic rhinitis. Pharmacotherapy Handbook. Eighth Edition. 2011. 1655.

2. Dexchlorpheniramine. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubchem. [Accessed on 3rd December 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Dexchlorpheniramine

3. J.K. Aronson. Dexchlorpheniramine. Science Direct. [Accessed on 3rd December 2022]. https://www.sciencedirect.com/topics/neuroscience/dexchlorpheniramine

4. Bayer New Zealand Limited. [Revised in February 2020] [Accessed on 3rd December 2022]. https://www.medsafe.govt.nz/profs/datasheet/p/Polaraminetabreptabsyrup.pdf

5. Bayer Australia Limited. NPS medicine wise. [Revised in November 2019] [Accessed on 3rd December 2022]. https://www.nps.org.au/medicine-finder/polaramine-tablets#full-pi

6. Yash Pharma Laboratories Pvt. Ltd. DexCPM-SR (Dexchlorpheniramine). [Accessed on 3rd December 2022]. http://yashpharma.com/product-details/dexcpm-sr/

Useful Diagnostic Tests

• Absolute Eosinophil Count
• Peripheral Smear Examination
• Total IgE