Introduction About DERMOTREX GEL

Psoriasis is a skin condition characterized by itchy scales that is not responsive to conventional managements such as phototherapy and retinoids. Vitiligo is a skin condition characterized by a loss of pigmentation, resulting in the appearance of discoloured patches on the skin.

Before using DERMOTREX GEL, it is recommended to inform the doctor about your medical and family history, including the list of medicines (prescription, non-prescription medicines, and herbal medicines) that are being used or taken.

DERMOTREX GEL is not recommended to be used by children less than 3 years of age, pregnant women, nursing women, or women planning to get pregnant. Consult your doctor before using the medicine.

• psoriasis
• active rheumatoid arthritis in adults (a complex auto-immune disorder resulting in the inflammation of the bones leading to swelling and pain)

Inform your doctor if you are using or taking any prescription, non-prescription medicines, ayurvedic, or herbal supplements.

Overdosage:

If you use too much of this medicine, consult your doctor immediately and visit any nearby hospital.

A: DERMOTREX GEL is used to manage psoriasis. It is a skin condition characterized by itchy scales that is not responsive to conventional managements such as phototherapy and retinoids. It is also used to manage active rheumatoid arthritis in adults, which is a complex auto-immune disorder resulting in the inflammation of the bones, leading to swelling and pain.

Q: Can I use DERMOTREX GEL in pregnancy?

A: DERMOTREX GEL is not recommended for use in pregnant women and/or in women who are planning pregnancy because it can be harmful for the fetus (growing baby in the womb). Consult your doctor before using it.

Q: Can I use DERMOTREX GEL if I am breastfeeding a baby?

A: DERMOTREX GEL is not recommended for use during breastfeeding due to a lack of safety data. Consult your doctor before applying it.

Q: Can DERMOTREX GEL be used by children?

A: DERMOTREX GEL is not recommended for children less than 3 years of age. For children above the age of 3, it is recommended to closely monitor for side effects. It is recommended to consult a doctor before giving DERMOTREX GEL to your child.

2. Eskicirak, B., Zemheri, E. and Cerkezoglu, A., 2006. The treatment of psoriasis vulgaris: 1% topical methotrexate gel. International journal of dermatology. [Published in August 2006] [Accessed on 3rd February 2024] https://pubmed.ncbi.nlm.nih.gov/16911386/

3. Abdelmaksoud, A., Dave, D.D., Lotti, T. and Vestita, M., 2019. Topical methotrexate 1% gel for treatment of vitiligo: A case report and review of the literature. Dermatologic Therapy. [Published on 1st September 2019] [Accessed on 3rd February 2024] https://www.semanticscholar.org/paper/Topical-methotrexate-1-gel-for-treatment-of-A-case-Abdelmaksoud-Dave/0e38f07bfca67bdba9d7cbfe927122d0f136e134

4. DAS, S., Sharadha, M., Venkatesh, M.P., SAHOO, S., TRIPATHY, J. and Gowda, D.V., 2021. Formulation and evaluation of topical nanoemulgel of methotrexate for rheumatoid arthritis. International Journal of Applied Pharmaceutics. [Revised on 22nd June 2021] [Accessed on 3rd February 2024] https://innovareacademics.in/journals/index.php/ijap/article/view/41026/25364

5. Liver Tox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Methotrexate. [Updated on 19th February 2020] [Accessed on 3rd February 2024] https://www.ncbi.nlm.nih.gov/books/NBK548219/#:~:text=Methotrexate%20can%20lead%20to%20serious,regimens%20and%20in%20higher%20doses.

6. Drugs.com Methotrexate Pregnancy and Breastfeeding Warnings. [Updated on 8th June 2022] [Accessed on 3rd February 2024] https://www.drugs.com/pregnancy/methotrexate.html

7. Journal of the Turkish Academy of dermatology. Methotrexate in Psoriasis: From A to Z. Abdulla Saleh, Mohn’d Abuhilal, Bernard Cheung, MBChB, MRCP (UK), MSc Derm. [Published in 2010] [Accessed on 3rd February 2024] https://cms.galenos.com.tr/Uploads/Article_32345/jtad-4-0-En.pdf

8. Meth Gel. West Coast Pharmaceutical Works Ltd. [Accessed on 3rd February 2024] https://westcoastin.com/cosmetic/meth-gel/1642