CRISNUO Ointment 20g
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Introduction About CRISNUO OINTMENT
CRISNUO Ointment is a steroid-free topical medicine indicated in the management of signs associated with mild to moderate atopic dermatitis/eczema (such as skin dryness, itchiness, rashes, raised bumps on the skin, skin redness and inflammation). It is suitable for use both in adults and in children aged 3 months or older. It contains a medicine called Crisaborole which is a phosphodiesterase 4 inhibitor that is thought to exerts its effects by blocking the release of certain chemicals that triggers allergic reactions of the skin.
CRISNUO Ointment is for external use only. Wash your hands before and after application. Apply a thin layer of CRISNUO Ointment over the affected skin areas. Avoid contact of CRISNUO Ointment with your eyes, ears, nose, mouth, vagina or other mucosal areas.
Before using CRISNUO Ointment inform your doctor if you are pregnant, think you may be pregnant or breastfeeding, as it is not known whether CRISNUO Ointment could harm the unborn baby or pass through breast milk. Do not use CRISNUO Ointment if you are allergic to Crisaborole or other ingredients of this medicine.
CRISNUO Ointment may cause Application site reactions or burning or stinging sensation following application in some individuals. Consult your doctor if it troubles you.
Uses Of CRISNUO OINTMENT
- Management of signs associated with mild to moderate atopic dermatitis/eczema (such as skin dryness, itchiness, rashes, raised bumps on the skin, skin redness and inflammation)
How CRISNUO OINTMENT Works
CRISNUO Ointment is a phosphodiesterase 4 inhibitor that penetrates the skin cells and targets and blocks the release of phosphodiesterase 4, an enzyme whose overactivity is thought to trigger allergic response in the skin. This action is believed to subside the allergic skin reactions associated with eczema.
How to use CRISNUO OINTMENT
Use CRISNUO Ointment under medical supervision. It is for external use only. Wash your hands before and after application. Apply a thin layer of CRISNUO Ointment over the affected skin areas. Do not apply too much of this medicine or use more than the required duration without consulting your doctor.
Avoid contact of CRISNUO Ointment with your eyes, ears, nose, mouth, vagina or other mucosal areas. Your doctor will decide the correct dose and duration of therapy for your based on your age, and severity of the skin condition.
Side Effects Of CRISNUO OINTMENT
Common
- Application site reactions
- Burning or stinging sensation
Stop using CRISNUO Ointment and inform your doctor immediately if you experience any:
- severe allergic reactions (such as severe skin rashes, itching, swelling of eyes, eyelids, lips, nose, throat, difficulty in breathing or swallowing, feeling faint)
How To Manage Side Effects

Application Site Reactions
Gently wash the affected area with mild soap and cool water to remove any residual ointment. Apply a cold compress to reduce inflammation and soothe irritation. Over-the-counter hydrocortisone cream can help alleviate redness and itching but avoid using any new products without consulting a healthcare provider. If symptoms persist or worsen, seek medical advice promptly to rule out allergic reactions or other underlying conditions. Additionally, keeping a record of the reaction and the product used can help in future consultations.
Warning & Precautions

Pregnancy
Consult your doctorIt is not known whether CRISNUO Ointment will harm the unborn baby. Therefore, use this medicine only if prescribed by your physician if you are pregnant or think you may be pregnant.

Breastfeeding
Consult your doctorIt is not known whether CRISNUO Ointment can pass through breast milk. Therefore, use this medicine only if prescribed by your physician if you are a nursing woman.

Allergy
ContraindicatedDo not use CRISNUO Ointment if you are allergic to Crisaborole or any other ingredients of this medicine.

Use In Pediatrics
Consult your doctorCRISNUO Ointment can be used in children and adolescents (aged 3 months or older) if prescribed by the physician. The safety and effectiveness of CRISNUO Ointment in children aged below 3 months have not been established.

Use In Geriatrics
Consult your doctorThere is no proper research information regarding the use of CRISNUO Ointment in elderly patients. Therefore, consult your doctor for advice.
Interactions
Drug-Drug interactions:
Before using CRISNUO Ointment inform your doctor about all the medicines, including prescription medicines, non-prescription medicines and herbal preparations that you take orally as well as topically as a precaution.
Overdosage:
If you applied too much of CRISNUO Ointment, you might experience burning sensation in your skin. In such cases, rinse your skin with plenty of water. If irritation persists, consult your doctor.
Synopsis
| Drug | : | Crisaborole | 
| Pharmacological Category | : | Phosphodiesterase 4 inhibitor | 
| Therapeutic Indication | : | Atopic dermatitis | 
| Dosage Forms | : | Ointment | 
More Information
Storage
- Keep CRISNUO Ointment out of reach of children
- Store CRISNUO Ointment at room temperature
FAQs About CRISNUO OINTMENT
Q: What is CRISNUO Ointment used for?
A: CRISNUO Ointment is a steroid-free topical medicine indicated in the management of signs associated with mild to moderate atopic dermatitis/eczema (such as skin dryness, itchiness, rashes, raised bumps on the skin, skin redness and inflammation).
Q: How to use CRISNUO Ointment?
A: Wash your hands before and after application. Apply a thin layer of CRISNUO Ointment over the affected skin areas. It is for external use only. Avoid contact of CRISNUO Ointment with your eyes, ears, nose, mouth, vagina or other mucosal areas.
Q: How CRISNUO Ointment works?
A: CRISNUO Ointment is a phosphodiesterase 4 inhibitor that penetrates the skin cells and targets and blocks the release of phosphodiesterase 4, an enzyme whose overactivity is thought to trigger allergic response in the skin. This action is believed to subside the allergic skin reactions associated with eczema.
Q: Is CRISNUO Ointment a steroid medicine?
A: CRISNUO Ointment is a steroid-free topical medicine used for managing atopic dermatitis. It contains a medicine called Crisaborole which is a phosphodiesterase 4 inhibitor that is thought to exerts its effects by blocking the release of certain chemicals that triggers allergic reactions of the skin.
Q: Can we apply CRISNUO Ointment to children?
A: CRISNUO Ointment is suitable for use both in adults and in children aged 3 months or older. However, consult your doctor for advice before use.
Q: Can we use CRISNUO Ointment during pregnancy?
A: It is not known whether CRISNUO Ointment will harm the unborn baby. Therefore, use this medicine only if prescribed by your physician if you are pregnant or think you may be pregnant.
Q: What is the price of CRISNUO Ointment in India?
A: CRISNUO Ointment is available at Rs. 545 in India. You can purchase this medicine in online stores as well with best discounts.
Q: What precautions must be followed while using CRISNUO Ointment?
A: CRISNUO Ointment is for external use only. Wash your hands before and after application. Apply a thin layer of CRISNUO Ointment over the affected skin areas. Avoid contact of CRISNUO Ointment with your eyes, ears, nose, mouth, vagina or other mucosal areas. Before using CRISNUO Ointment inform your doctor if you are pregnant, think you may be pregnant or breastfeeding, as it is not known whether CRISNUO Ointment could harm the unborn baby or pass through breast milk. Do not use CRISNUO Ointment if you are allergic to Crisaborole or other ingredients of this medicine.
Q: Is CRISNUO Ointment safe?
A: Post-marketing experience shows that CRISNUO Ointment may cause Application site reactions or burning or stinging sensation in some individuals. Consult your doctor if it troubles you.
References
- Crisaborole: A Novel Nonsteroidal Topical Treatment for Atopic Dermatitis. NCBI. National Center for Biotechnology information. National Library of Medicine. August 2019. [Accessed on 17th June 2024]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600556/
- Once-Daily Crisaborole Ointment, 2%, as a Long-Term Maintenance Treatment in Patients Aged ≥ 3 Months with Mild-to-Moderate Atopic Dermatitis: A 52-Week Clinical Study. Springer Link. May 2023. [Accessed on 17th June 2024]. https://link.springer.com/article/10.1007/s40257-023-00780-w
- EUCRISA® (crisaborole) ointment, for topical use. Pfizer Laboratories Div Pfizer Inc. [Revised in April 2023]. [Accessed on 17th June 2024]. https://labeling.pfizer.com/ShowLabeling.aspx?id=5331
- EUCRISA Full Patient Information. Pfizer. Revised in April 2023]. [Accessed on 17th June 2024]. https://www.pfizermedicalinformation.com/patient/eucrisa/full-patient-information
- Eucrisa Ointment. December 2023. [Accessed on 17th June 2024]. https://www.eucrisa.com/learn-about-eucrisa
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