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Introduction About COXO 120 TABLET
COXO 120 TABLET is used to reduce pain and swelling associated with inflammatory bone conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (inflammation of the spine), and gout (joint pain caused by excessive accumulation of uric acid in between the joints). It can also be used to reduce pain following a dental surgery. It contains Etoricoxib, which belongs to the group of medicines called Non-Steroidal Anti-Inflammatory Drugs. It works by blocking the release of certain chemicals (prostaglandins) in the body that cause pain, swelling, and inflammation, thereby reducing pain and inflammation associated with inflammatory conditions.
Before taking COXO 120 TABLET, inform your doctor if you have any history of heart, liver, or kidney problems. You must also inform your doctor if you have diabetes, high blood cholesterol levels, uncontrollable high blood pressure, or severe dehydration. COXO 120 TABLET is strictly not recommended for use in patients with stomach problems (such as stomach ulcers, bleeding in the gut, or inflammatory bowel diseases). It is also not suitable for use in patients with stroke or any severe form of heart problems, liver problems, or kidney problems.
It is suitable for use in adults and adolescents (aged 16 years or older). Do not take COXO 120 TABLET if you are pregnant or breastfeeding without consulting your doctor. The most common side effects of taking COXO 120 TABLET are stomach pain, bloating, constipation, mouth ulcers. Consult your doctor immediately if any of these side effects worsen.
Uses Of COXO 120 TABLET
It is used in adults and in adolescents (aged 16 years or older) to:
- Manage pain and swelling caused by inflammation of bones and joints
- Manage pain following dental surgery
How COXO 120 TABLET Works
COXO 120 TABLET is a pain-relieving medicine. It works by blocking the release of certain chemicals (prostaglandins) in the body that cause pain, swelling, and inflammation, thereby reducing pain and inflammation associated with inflammatory conditions.
How to use COXO 120 TABLET
- Take COXO 120 TABLET as advised by your physician
- Swallow the medicine with a glass of water. Do not crush or chew the medicine
- COXO 120 TABLET can be taken with or without food
- Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and disease condition
Side Effects Of COXO 120 TABLET
Common side effects of COXO 120 TABLET:
- stomach pain
- constipation, flatulence, heartburn, indigestion, diarrhea
- mouth ulcer
- feeling weak or tired
- infections of the respiratory or urinary tract
- tingling and numbness in the body
- changes in bowel habits, dry mouth, stomach ulcers
Stop taking COXO 120 TABLET and contact your doctor immediately if you experience any of the following side effects:
- chest pain, shortness of breath, swollen ankles
- severe stomach pain with dark stools
- jaundice (yellow colouration of the skin and the eyes)
- signs of an allergic reaction (such as skin rash, itching, blistering, and peeling of the skin, swelling of the face, lips, mouth, and throat, which may lead to breathing difficulties)
Warning & Precautions
Pregnancy
ContraindicatedCOXO 120 TABLET should not be used during pregnancy. Therefore, inform your doctor before taking the medicine if you are pregnant, think you may be pregnant, or are planning to have a baby.
Breastfeeding
Consult your doctorIt is not known whether COXO 120 TABLET can pass through breast milk or not. Therefore, consult your doctor before taking the medicine if you are breastfeeding or planning to breastfeed.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if you feel dizzy or sleepy after taking the medicine.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking COXO 120 TABLET, as it may increase the risk of stomach discomfort.
Kidney
ContraindicatedCOXO 120 TABLET is not recommended for use in patients with serious kidney diseases.
Liver
ContraindicatedCOXO 120 TABLET is not recommended for use in patients with serious liver diseases.
Allergy
ContraindicatedDo not take COXO 120 TABLET if you are allergic to Etoricoxib or any ingredients of this medicine.
Heart Disease
ContraindicatedCOXO 120 TABLET is not recommended for use in patients who have or had heart failure, angina, heart attack, bypass surgery, blocked blood vessels, or poor blood circulation in the body.
Use In Pediatrics
Monitoring requiredCOXO 120 TABLET should be used in adolescents aged 16 years or above only if prescribed by the physician. It should not be used in children and adolescents (aged below 16 years).
Use In Geriatrics
Use with CautionCOXO 120 TABLET should be used with caution in elderly patients (aged above 65 years).
Others
COXO 120 TABLET is not recommended for use if you:
- currently have ulcers or bleeding in stomach or intestines
- have inflammatory bowel diseases (crohn’s disease or ulcerative colitis)
- have uncontrollably high blood pressure
- had stroke (including mini-stroke, transient ischemic attack)
Before taking COXO 120 TABLET, inform your doctor if you
- have a previous history of stomach ulcers
- are dehydrated due to prolonged vomiting or diarrhea
- have a history of high blood pressure
- have edema (swelling of body parts)
- are being managed for an infection
- have diabetes
- have high cholesterol
- are a smoker
Interactions
A. Drug-Drug interactions:
Before taking COXO 120 TABLET, inform your doctor if you are taking any of the following medicines, such as:
- Anticoagulant (Ex. Warfarin)
- Antibiotics (Ex. Rifampicin)
- Antimetabolites (Ex. Methotrexate)
- Immunosuppressants (Ex. Cyclosporin, Tacrolimus)
- Anti-maniac agents (Ex. Lithium)
- ACE inhibitors (Ex. enalapril, ramipril)
- Angiotensin receptor blockers (Ex. losartan, valsartan)
- Diuretics (Ex. bumetanide, ethacrynic acid)
- Cardiac glycosides (Ex. Digoxin)
- Vasodilators (Ex. Minoxidil)
- Bronchodilators (Ex. Salbutamol)
- Antiprogestational steroids (Ex. mifepristone, drospirenone, ethinylestradiol)
- Hormone replacement therapy (Ex. estradiol, dydrogesterone)
- Nonsteroidal anti-inflammatory drug (NSAID) (Ex. Aspirin)
Overdosage:
If you or anyone else accidentally took more of COXO 120 TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Etoricoxib |
| Pharmacological Category | : | Selective COX-2 Inhibitor |
| Therapeutic Indication | : | Pain relief |
| Dosage Forms | : | Tablet, Capsule, Injection |
FAQs About COXO 120 TABLET
Q: Is COXO 120 TABLET safe to use in diabetic patients?
A: It may alter the blood sugar levels in the body. Therefore, it is necessary to inform your doctor if you have diabetes before taking the medicine as a precaution.
Q: Is COXO 120 TABLET an anti-inflammatory medicine?
A: Yes. It is an anti-inflammatory medicine used to reduce pain and inflammation. It acts by blocking the release of certain chemicals (Ex. prostaglandins) in the body that cause pain and inflammation.
Q: Who should not take COXO 120 TABLET?
A: Generally, patients who have stomach problems like stomach ulcers or other inflammatory stomach conditions such as ulcerative colitis, Crohn’s disease, or perforations or bleeding in the gut should not take the medicine. Consult your doctor before taking this medicine if you are pregnant or trying to become pregnant. COXO 120 TABLET is also not suitable for use in patients with stroke or severe liver, kidney, or heart disease and in children aged below 16 years.
Q: Is COXO 120 TABLET safe to use for the long term?
A: Research shows that prolonged use of COXO 120 TABLET can increase the risk of heart attack or stroke in some patients. Your doctor will regularly monitor health condition while taking the medicine to avoid these side effects.
Q: Can I take other painkillers along with COXO 120 TABLET?
A: No, it is not advisable to take other painkillers along with COXO 120 TABLET without consulting your doctor, as it may increase the risk of ulcers and bleedings in the digestive system.
Q: Is it safe to have COXO 120 TABLET with alcohol?
A: No. Avoid consumption of alcohol while taking COXO 120 TABLET, as it increases the risk of unwanted gastrointestinal side effects.
Q: Can COXO 120 TABLET cause dizziness?
A: Yes. COXO 120 TABLET may make you feel dizzy. If you experience dizziness, try to rest and relax. Get enough sleep. Avoid driving or operating any heavy tools or machines while you are feeling dizzy. Avoid consumption of alcohol, as it can aggravate your dizziness. Consult your doctor if you continue to feel dizzy for a prolonged period.
Q: Can I take a higher dose of COXO 120 TABLET?
A: It is not safe to take a higher dose of COXO 120 TABLET without consulting your doctor. If the prescribed dose is less effective for you, kindly consult your doctor for a suitable high dose or for alternative therapy.
Q: How long will it take for COXO 120 TABLET to reduce pain?
A: It may take around 20-30 minutes for COXO 120 TABLET to start working. The maximum benefits can be achieved after 2 hours of taking COXO 120 TABLET. However, this period may vary from person to person depending upon the dose of etoricoxib that is administered.
Q: What happens if I accidentally take more COXO 120 TABLET?
A: If you or anyone else accidentally take more COXO 120 TABLET, contact your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include severe stomach problems such as stomach pain, bleeding in the gut, and a fast heartbeat.
Q: Can I take COXO 120 TABLET daily?
A: Your doctor will evaluate the health condition and suggest whether you can take COXO 120 TABLET every day or not.
Q: Can I stop taking COXO 120 TABLET once my pain reduces?
A: Take COXO 120 TABLET for the stipulated duration recommended by your doctor to achieve maximum results. Do not stop therapy with COXO 120 TABLET without consulting your doctor in between the therapy.
Q: What are the uses of COXO 120 TABLET?
A: COXO 120 TABLET is used to reduce pain and swelling associated with inflammatory bone conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout. It can also be used to reduce pain following dental surgery.
Q: Can COXO 120 TABLET be used in children?
A: Yes. COXO 120 TABLET should be used in adolescents aged 16 years or above only if prescribed by the physician.
Q: How does COXO 120 TABLET work?
A: COXO 120 TABLET is a pain-relieving medicine. It works by blocking the release of certain chemicals (prostaglandins) in the body that cause pain, swelling, and inflammation, thereby reducing pain and inflammation associated with inflammatory conditions.
Q: What are the side effects of COXO 120 TABLET?
A: The most common side effects of taking COXO 120 TABLET are stomach pain, bloating, constipation, mouth ulcers, headache, and dizziness. Consult your doctor immediately if any of these side effects worsen.
Q: What is the best time to take COXO 120 TABLET?
A: COXO 120 TABLET can be taken with or without meals. Your doctor will decide the best time for you to take COXO 120 TABLET based on your age, body weight, and disease condition.
Q: What to do if I forgot to take a dose of COXO 120 TABLET?
A: If you forgot to take a dose of COXO 120 TABLET, take it as soon as you remember. However, if it is time for the next dose of COXO 120 TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of COXO 120 TABLET to compensate for the missed ones.
Q: Will COXO 120 TABLET alter the effects of birth control pills?
A: COXO 120 TABLET may reduce the effects of birth control pills. Therefore, try to avoid taking birth control pills along with this medicine.
References
1. KD. Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 206.
2. Wen-Nan Huang and Tim K. Tso. Etoricoxib improves osteoarthritis pain relief, joint function, and quality of life in the extreme elderly. NIH National Library of Medicine, National Center for Biotechnology Information. PMC PubMed Central. [Revised in February 2018] [Accessed on 30th July 2024] click here
3. Merck Sharp & Dohme B.V. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 30th July 2024] click here
4. Teva UK Limited. Etoricoxib. [Revised in August 2022] [Accessed on 30th July 2024] click here
Author Details
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
